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  3. Kephazon 1gm I.V

Kephazon 1gm I.V, Pack of 1 INJECTION
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Composition :

CEFOPERAZONE-1GM

Manufacturer/Marketer :

Galcare Pharmaceuticals Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Kephazon 1gm I.V

Kephazon 1gm I.V belongs to the group of medicines called antibiotics used to treat various bacterial infections such as respiratory tract (lungs) infection, urine infection, blood infection, meningitis (inflammation of the brain and spinal cord), gonorrhoea (sexually transmitted disease), skin, abdominal, bone, and joint infections. Bacterial infections are caused due to the multiplication of harmful bacteria inside or on the body. Infectious or harmful bacteria can make you sick and reproduce quickly in your body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you ill. Kephazon 1gm I.V does not work against infections caused by the virus, including cold and flu.

Kephazon 1gm I.V is an antibiotic that contains Cefoperazone (cephalosporin antibiotic). Kephazon 1gm I.V works by preventing the formation of bacterial cell covering, which is necessary for their survival by binding to the penicillin-binding proteins (PBPs), thus preventing cross-linking of nascent peptidoglycan and killing the bacteria. Thereby, Kephazon 1gm I.V helps to treat bacterial infections.

You may experience diarrhoea, allergic reactions, abnormal liver function tests, and anaemia (a low number of red blood cells). Most of these side effects of Kephazon 1gm I.V do not require medical attention and gradually resolve over time. However, if they persist, consult your doctor.

Before starting Kephazon 1gm I.V, please inform your doctor if you have any allergy (against any antibiotic), kidney or liver problems. Do not take Kephazon 1gm I.V on your own as self-medication may lead to antibiotic-resistance in which antibiotics fail to act against specific bacterial infections. Inform your doctor before taking Kephazon 1gm I.V if you are pregnant or planning for pregnancy. Avoid taking Kephazon 1gm I.V if you are breastfeeding as Kephazon 1gm I.V may pass into breast milk. Avoid alcohol consumption while taking Kephazon 1gm I.V to prevent unpleasant side effects.

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication.• Kephazon 1gm I.V is administered by the doctor or nurse.• Do not self-administer.

Medicinal Benefits

Kephazon 1gm I.V belongs to the group of medicines called antibiotics used to treat various bacterial infections such as respiratory tract (lungs) infection, urine infection, blood infection, meningitis (inflammation of the brain and spinal cord), gonorrhoea (sexually transmitted disease), skin, abdominal, bone, and joint infections. Kephazon 1gm I.V contains Cefoperazone (cephalosporin antibiotic). It works by preventing the formation of bacterial cell covering, which is necessary for their survival by binding to the penicillin-binding proteins (PBPs), thus preventing cross-linking of nascent peptidoglycan and killing the bacteria. Thus, Kephazon 1gm I.V helps to treat bacterial infections.

How Kephazon 1gm I.V Works

Kephazon 1gm I.V is an antibiotic that contains Cefoperazone (cephalosporin antibiotic). Kephazon 1gm I.V works by preventing the formation of bacterial cell covering, which is necessary for their survival by binding to the penicillin-binding proteins (PBPs), thus preventing cross-linking of nascent peptidoglycan and kills the bacteria. Thereby, Kephazon 1gm I.V helps to treat bacterial infections.

Storage

Store in a cool and dry place away from sunlight
Side effects of Kephazon 1gm I.V
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.
  • Maintain a healthy diet with fruits, whole grains, and vegetables.
  • Include easy-to-digest and antioxidant-rich food in your diet.
  • Drink plenty of water and unsweetened liquids.
  • Limit sugary foods, alcohol, refined carbs and fried foods.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.

What if I have taken an overdose of Kephazon 1gm I.V

Kephazon 1gm I.V is administered by a health care professional in a hospital setting. Hence, the chances of overdose are less. However, if you suspect any adverse reactions or unusual symptoms while on treatment with Kephazon 1gm I.V, please inform your doctor immediately.

Drug Warnings

After taking Kephazon 1gm I.V if you have allergy-like symptoms including rash, swelling of the face/lips/throat, difficulty in breathing, or tightness in the chest, immediately contact your doctor. Do not take Kephazon 1gm I.V if you have an allergy to Kephazon 1gm I.V, cephalosporins penicillin class of antibiotics as it may cause a skin rash, itching, and difficulty in breathing. People having liver disease or jaundice (yellowing of skin/eye) should not take Kephazon 1gm I.V, as it can damage your liver severely. You may have diarrhoea in some cases as a common side effect which can be managed by taking it with any probiotics and plenty of fluids. Do not take antacids along with Kephazon 1gm I.V; maintain a gap of 2-3 hours between both. Avoid alcohol consumption while taking Kephazon 1gm I.V to prevent unpleasant side-effects. Kephazon 1gm I.V may cause dizziness, so be cautious while driving. Inform your doctor about all the medicines you are taking and about your health condition to rule out any unpleasant side-effects.

Drug-Drug Interactions

verifiedApollotooltip
CefoperazoneBCG vaccine
Critical
CefoperazoneRifampicin
Severe

Drug-Drug Interactions

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CefoperazoneBCG vaccine
Critical
How does the drug interact with Kephazon 1gm I.V:
When BCG vaccine is used with Kephazon 1gm I.V, its effectiveness may be reduced.

How to manage the interaction:
Taking Kephazon 1gm I.V with BCG vaccine is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor
CefoperazoneRifampicin
Severe
How does the drug interact with Kephazon 1gm I.V:
Taking Kephazon 1gm I.V and Rifampicin together may increase the risk of bleeding.

How to manage the interaction:
Although there is an interaction between Kephazon 1gm I.V and rifampicin, they can be taken together if prescribed by a doctor. However, if you experience vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Probiotics should be taken after taking the entire course of Kephazon 1gm I.V to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut, kombucha, and kimchi can help to restore the good bacteria of the intestine.
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria, which helps stimulate their growth. Thus, fibre-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains like whole-grain bread and brown rice should be included in your diet.
  • Avoid intake of alcoholic beverages with Kephazon 1gm I.V as it can make you dehydrated and may affect your sleep. This can make it harder for your body to aid the Kephazon 1gm I.V in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTI- BACTERIALS

Kephazon 1gm I.V Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Avoid consuming alcohol while taking Kephazon 1gm I.V as it causes increased side effects.

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Pregnancy

Consult your doctor

Please consult your doctor if you are pregnant, your doctor will prescribe Kephazon 1gm I.V only if the benefits outweigh the risks.

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Breast Feeding

Caution

A small amount of Kephazon 1gm I.V may pass into breast milk. Avoid taking Kephazon 1gm I.V if you are breastfeeding unless prescribed.

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Driving

Caution

Kephazon 1gm I.V may cause dizziness in some people, so it may affect your ability to drive.

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Liver

Consult your doctor

Dose adjustment may be needed. Please consult your doctor before taking Kephazon 1gm I.V if you have liver impairment/liver disease.

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Kidney

Consult your doctor

Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease before taking Kephazon 1gm I.V.

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Children

Safe if prescribed

For children, Kephazon 1gm I.V is safe if prescribed by the doctor. Consult your doctor for more infoemation.

Have a query?

FAQs

Kephazon 1gm I.V is used to treat various bacterial infections, such as respiratory tract (lungs) infections, urine infections, blood infections, meningitis (inflammation of the brain and spinal cord), gonorrhoea (sexually transmitted disease), and skin, abdominal, bone, and joint infections.

Kephazon 1gm I.V is an antibiotic that contains Cefoperazone (cephalosporin antibiotic). Kephazon 1gm I.V works by preventing the formation of bacterial cell covering, which is necessary for their survival by binding to the penicillin-binding proteins (PBPs), thus preventing cross-linking of nascent peptidoglycan and kills the bacteria. Thereby, Kephazon 1gm I.V helps to treat bacterial infections.

Inform your doctor if you do not feel better even after finishing the full course of treatment. You must also inform your doctor if the symptoms get worse while using this medicine.

Usually, Kephazon 1gm I.V starts working soon after taking it. It may take a few days to kill all the dangerous bacteria and make you feel better.

Kephazon 1gm I.V may cause Clostridium difficile-associated diarrhoea (CDAD). Treatment with antibiotics alters the normal flora, leading to overgrowth of Clostridium difficile; this causes diarrhoea. Drink lots of fluids and eat fibre-rich food if you experience diarrhoea. If you find blood in your stools (tarry stools) or if you experience prolonged diarrhoea with abdominal pain, stop taking Kephazon 1gm I.V and consult your doctor. Do not take anti-diarrhoeal medicine on your own.

It's generally not recommended to consume alcohol while taking Kephazon 1gm I.V, as it can increase gastrointestinal issues, enhance sedative effects, and interfere with the antibiotic's effectiveness. Consult your doctor for personalized advice.

As Kephazon 1gm I.V is administered in a hospital by a healthcare provider, Therefore, the chances of missing a dose is less. However, if you have any concerns, contact your doctor. Do not self-administer.

Common side effects of Kephazon 1gm I.V include diarrhoea, allergic reactions, abnormal liver function tests, and anemia. Most of these side effects are temporary and resolve on their own. However, if they persist, consult your doctor for proper evaluation and guidance.

Country of origin

India

Manufacturer/Marketer address

Galcare Pharmaceuetical Pvt. Ltd, 53 – 54 Basement, Devi Nagar, Jaipur
Other Info - KEP0005

Disclaimer

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Reference

  1. https://go.drugbank.com/drugs/DB01329
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/050551s043lbl.pdf
  3. https://labeling.pfizer.com/ShowLabeling.aspx?id=14801#:~:text=Cefoperazone%20contains%2034%20mg%20sodium,The%20empirical%20formula%20is%20C25H26N9NaO8S2.
  4. https://www.mayoclinic.org/drugs-supplements/cefoperazone-intramuscular-route-intravenous-route/description/drg-20406573
  5. https://www.drugs.com/drug-interactions/cefoperazone-with-lasix-548-0-1146-676.html#:~:text=Interactions%20between%20your%20drugs&text=Cephalosporin%20antibiotics%20like%20cefoperazone%20can,furosemide%20may%20increase%20that%20risk.

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