Knogle 200 Nasal Spray 60Md 6Ml is primarily indicated for the treatment of postmenopausal osteoporosis in women more than five years postmenopause when alternative therapies are unsuitable. Post-menopausal osteoporosis is a medical condition that causes thinning and weakening of the bones during/after a menopausal period.

Knogle 200 Nasal Spray 60Md 6Ml contains Calcitonin, a human hormone that prevents bone breakdown and increases bone density (thickness). Thus, it helps treat osteoporosis in postmenopausal women.

Use Knogle 200 Nasal Spray 60Md 6Ml as prescribed by the doctor. Knogle 200 Nasal Spray 60Md 6Ml may cause certain side effects such as hypocalcemia, runny nose, nosebleed, sinus pain, application site reactions such as rhinitis (stuffy nose), epistaxis (nose bleeds) and other nasal symptoms, back pain, arthralgia (Joint pain) and headache. Most of these side effects do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.

Knogle 200 Nasal Spray 60Md 6Ml is for intranasal use only; do not inject or take it orally. Before using Knogle 200 Nasal Spray 60Md 6Ml, inform your doctor of all your medical conditions, sensitivities, and medications. Knogle 200 Nasal Spray 60Md 6Ml is intended for post-menopausal women; therefore, it should not be recommended for other populations. Avoid drinking alcohol because it affects how the body absorbs calcium and vitamin D, which are essential for good bone formation.

Knogle 200 Nasal Spray 60Md 6Ml is used in the treatment of Postmenopausal osteoporosis. The detailed uses of Knogle 200 Nasal Spray 60Md 6Ml are as follows:

• Treat postmenopausal osteoporosis: Knogle 200 Nasal Spray 60Md 6Ml helps slow bone loss and increase bone density in women who are at least five years past menopause. It reduces the risk of vertebral fractures by mimicking the natural hormone calcitonin, which regulates calcium levels and inhibits bone breakdown.
• Manage bone pain in Paget’s disease: Knogle 200 Nasal Spray 60Md 6Ml alleviates bone discomfort associated with abnormal bone remodeling in Paget’s disease by suppressing osteoclast activity and stabilizing bone turnover.

• Follow your doctor’s instructions on the dosage and timing of this medication to ensure safety.
• Remove the cap of the bottle, insert the tip into a nostril while closing the other nostril, and spray towards the sides of the nostril. Keep your head straight and breathe gently. Repeat the same process for another nostril.
• Wipe the nozzle with a clean tissue and replace the cap after each use.

Knogle 200 Nasal Spray 60Md 6Ml contains Calcitonin, a calcitonin receptor agonist that prevents the loss of bones that happens after menopause and helps to rebuild bones. Calcitonin is a hormone that the C-cells in the thyroid gland produce and release. It opposes the parathyroid hormone's action, helping regulate the blood’s calcium and phosphate levels. Knogle 200 Nasal Spray 60Md 6Ml works by suppressing the activity of the osteoclasts (cells that break down bone). When the osteoclasts break down bone tissue, the calcium enters the bloodstream. Knogle 200 Nasal Spray 60Md 6Ml lessens the amount of calcium in the blood by preventing the breakdown of bone. Thereby, Knogle 200 Nasal Spray 60Md 6Ml strengthens the bones and minimizes the risk of fractures. Knogle 200 Nasal Spray 60Md 6Ml also seems to decrease the amount of calcium the kidneys can re-absorb, lowering calcium levels further.

Before using Knogle 200 Nasal Spray 60Md 6Ml, Inform your doctor about all your medical conditions, sensitivities, and all medications you are using. Knogle 200 Nasal Spray 60Md 6Ml is intended for post-menopausal women; therefore, Knogle 200 Nasal Spray 60Md 6Ml should not be recommended for other populations. In rare situations, individuals using Knogle 200 Nasal Spray 60Md 6Ml may be affected with anaphylactic shock (a sudden, severe, life-threatening allergic reaction leading to difficulty breathing); if you encounter it, stop using Knogle 200 Nasal Spray 60Md 6Ml and contact your doctor immediately.