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Koate-DVI 500 IU Injection 5 ml belongs to the group of medications called hematologic agents used to prevent or reduce bleeding episodes in individuals with haemophilia A, a genetic disorder caused by a missing or defective blood clotting factor. Koate-DVI 500 IU Injection 5 ml works by replacing the missing or deficient clotting factor VIII in individuals with haemophilia A. This helps restore the ability of blood to clot, prevent or treat bleeding episodes, and reduces the risk of spontaneous bleeds or bleeding during physical activities. You may experience common side effects like chills, rash, flushing (sudden reddening of the skin), nausea and dizziness.
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About Koate-DVI 500 IU Injection 5 ml
Koate-DVI 500 IU Injection 5 ml is used in the treatment and prevention of bleeding in patients with haemophilia A. Hemophilia A is a genetic bleeding disorder caused by a deficiency or absence of clotting factor VIII that impairs the blood’s ability to clot. It leads to prolonged bleeding episodes, often following injuries or surgeries, and can cause spontaneous internal bleeding.
Koate-DVI 500 IU Injection 5 ml contains Dried human antihemophilic factor VIII fraction, which works by replacing the missing or deficient clotting factor VIII in individuals with haemophilia A. This helps restore the blood's clotting ability, preventing or treating bleeding episodes. As a result, it helps in managing bleeding and reducing the risk of spontaneous bleeds or bleeding during physical activities.
The dose and duration of treatment with Koate-DVI 500 IU Injection 5 ml may vary based on your medical condition being treated. The common side effects of Koate-DVI 500 IU Injection 5 ml include chills, rash, flushing (sudden reddening of the skin), nausea and dizziness. Most of these side effects may resolve gradually over time on their own. However, consult the doctor if any of these symptoms persist or worsen.
Inform your doctor if you are pregnant or planning to become pregnant or breastfeeding while treatment with Koate-DVI 500 IU Injection 5 ml to evaluate the potential risks and benefits. Koate-DVI 500 IU Injection 5 ml is safe for children if prescribed by the doctor. Koate-DVI 500 IU Injection 5 ml may cause dizziness; therefore, avoid driving or operating heavy machinery unless fully alert. Inform your doctor about all the medicines you are taking and about your pre-existing health conditions to rule out any unpleasant side effects/interactions.
Uses of Koate-DVI 500 IU Injection 5 ml
Koate-DVI 500 IU Injection 5 ml is used to treat and prevent bleeding in patients with hemophilia A, a genetic disorder caused by a deficiency of factor VIII. The detailed uses of Koate-DVI 500 IU Injection 5 ml are as follows:

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Directions for Use
Medicinal Benefits
Koate-DVI 500 IU Injection 5 ml belongs to the group of medications called hematologic agents. It contains dried human antihaemophilic factor VIII fraction, which replicates the function of factor VIII, a crucial protein for blood clotting. It connects activated factor IX and factor X, promoting effective clot formation in individuals with hemophilia A. This process helps prevent and minimize bleeding episodes, including in patients with factor VIII inhibitors. It is used for the treatment and prevention of bleeding in patients with haemophilia A, a genetic bleeding disorder caused by a deficiency of factor VIII.
How Koate-DVI 500 IU Injection 5 ml Works
Storage
What if I have taken an overdose of Koate-DVI 500 IU Injection 5 ml
Drug Warnings
Koate-DVI 500 IU Injection 5 ml may cause severe allergic reactions in some individuals, including anaphylaxis, which requires immediate discontinuation of treatment. Notify your doctor if you experience any symptoms, like difficulty breathing or dizziness. Inform your doctor if you have any risk factors, as thromboembolic events, including blood clots like pulmonary embolism, can occur, particularly in patients with immobility, surgery, or obesity. Since the product is derived from human plasma, there is a potential risk of transmitting infectious agents, even with viral inactivation and screening precautions. Therefore, Inform your doctor if you experience any symptoms or signs of infection. It is essential to regularly monitor your Factor VIII levels, especially during active bleeding or treatment, to ensure you are receiving the correct dosage.
Diet & Lifestyle Advise
Habit Forming
Therapeutic Class
Alcohol
Consult your doctor
The interaction of alcohol with Koate-DVI 500 IU Injection 5 ml is unknown. If you have any concerns, discuss with your doctor.
Pregnancy
Consult your doctor
Please inform your doctor if you are pregnant or planning to become pregnant; your doctor will administer Koate-DVI 500 IU Injection 5 ml only if the benefits outweigh the risks.
Breast Feeding
Consult your doctor
It is unknown if Koate-DVI 500 IU Injection 5 ml passes into breast milk. Therefore, please inform your doctor if you are breastfeeding. Your doctor decides based on the benefits and risks of Koate-DVI 500 IU Injection 5 ml to the mother and baby.
Driving
Caution
Koate-DVI 500 IU Injection 5 ml may cause dizziness. Therefore, do not drive or operate machinery unless you are fully alert.
Liver
Consult your doctor
Please inform your doctor if you have liver impairment/liver disease before receiving Koate-DVI 500 IU Injection 5 ml.
Kidney
Consult your doctor
Please inform your doctor if you have kidney impairment/kidney disease before receiving Koate-DVI 500 IU Injection 5 ml.
Children
Safe if prescribed
Koate-DVI 500 IU Injection 5 ml is safe for children if prescribed by a doctor. The dose and duration may vary depending on the child’s weight and the severity of the child's medical condition.
Heart
If you have heart problems, Koate-DVI 500 IU Injection 5 ml can be used, but with caution and under close medical supervision.
Geriatrics
Caution
Geriatric patients can receive Koate-DVI 500 IU Injection 5 ml, but it should be done with caution and close medical supervision.
Koate-DVI 500 IU Injection 5 ml belongs to the group of medications called hematologic agents used for the treatment and prevention of bleeding in patients with haemophilia A, a genetic bleeding disorder caused by a deficiency of factor VIII.
Koate-DVI 500 IU Injection 5 ml may cause dizziness. Therefore, avoid driving or operating heavy machinery if you feel dizzy after taking Koate-DVI 500 IU Injection 5 ml unless you are fully alert.
Nausea might be a side-effect caused by Koate-DVI 500 IU Injection 5 ml. If you experience this symptom, drink plenty of water, avoid strong odours, drink ginger or peppermint tea, get fresh air, and practise some breathing exercises or meditation.
Koate-DVI 500 IU Injection 5 ml is contraindicated in patients who are allergic to any of its ingredients and have experienced life-threatening immediate hypersensitivity reactions to any of its ingredients, including anaphylaxis symptoms like difficulty breathing, swelling of the throat or tongue, hives, a rash, wheezing, a drop in blood pressure (leading to dizziness or fainting), and a fast or weak heartbeat.
If you don't get better after receiving Koate-DVI 500 IU Injection 5 ml, contact your healthcare provider and they may need to check for Factor VIII inhibitors or adjust your treatment plan.
The common side effects of Koate-DVI 500 IU Injection 5 ml include chills, rash, flushing (sudden reddening of the skin), nausea and dizziness. Consult the doctor if any of these side effects persist or worsen.
Koate-DVI 500 IU Injection 5 ml works by replacing the missing or deficient clotting factor VIII in individuals with hemophilia A. This helps restore the blood's clotting ability, preventing or treating bleeding episodes. As a result, it helps in managing bleeding and reducing the risk of spontaneous bleeds or bleeding during physical activities.
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Keep Refrigerated. Do not freeze.