KOLIGESIC MF TABLET
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About KOLIGESIC MF TABLET
KOLIGESIC MF TABLET is a prescription oral medication primarily used to treat painful muscle spasms in the stomach and abdomen, as well as menstrual cramps. It works by targeting both the sudden muscle contractions in your digestive tract and the pain pathways in your body. It is highly effective for relieving discomfort associated with heavy cramping and abdominal spasms.
KOLIGESIC MF TABLET is typically taken only when you experience symptoms or as a short-term course prescribed by your doctor. It is highly recommended to take KOLIGESIC MF TABLET with or immediately after a meal to protect your stomach lining from irritation. Making small adjustments like eating smaller, frequent meals, staying hydrated, and applying gentle heat to your abdomen can further support muscle relaxation and improve your overall comfort during treatment.
While taking KOLIGESIC MF TABLET, you may experience mild and temporary side effects like dry mouth, sleepiness, or mild dizziness. If you notice any serious issues, such as severe stomach pain, black or tarry stools, or signs of an allergic reaction, stop taking the medicine immediately and consult your doctor. Your safety is paramount, and these serious symptoms require prompt medical evaluation.
Talk to your doctor before taking KOLIGESIC MF TABLET if you have a history of stomach ulcers, asthma, glaucoma, or severe kidney or liver issues. Do not take KOLIGESIC MF TABLET if you have a complete blockage of your urinary tract or bowels, or if you have severe inflammatory bowel disease. Sharing your complete medical history ensures this treatment is safe for your body.
It is important to avoid alcohol while taking KOLIGESIC MF TABLET, as alcohol can significantly increase your risk of stomach bleeding and make you feel more drowsy. Always discuss with your healthcare provider if you are taking blood thinners, other pain relievers, or if you are pregnant, breastfeeding, or managing health conditions as an older adult.
Uses of KOLIGESIC MF TABLET
KOLIGESIC MF TABLET is used in the treatment of abdominal pain, dysmenorrhea (period pain), and colicky pain. The detailed uses of KOLIGESIC MF TABLET are as follows:
- Stomach and abdominal cramps: KOLIGESIC MF TABLET helps by relaxing the tight, spasming muscles in your stomach and intestines, providing quick relief from sharp pain.
- Menstrual period pain: It reduces the severe cramping and pain that occurs during your menstrual cycle by targeting the chemicals that cause uterine contractions.
- Irritable bowel syndrome (IBS) spasms: It calms the overactive gut muscles associated with IBS, helping to normalize digestion and reduce sudden, painful cramping.
Key Benefits
KOLIGESIC MF TABLET helps relieve abdominal and menstrual pain by reducing muscle spasms and easing discomfort. Addressing both cramping and pain at the same time, it helps improve comfort and supports normal daily activities. Benefits may include:
- Helps relieve abdominal cramps and spasm-related pain.
- Reduces menstrual cramps and associated discomfort.
- Helps relax smooth muscles and reduce painful contractions.
- Provides relief from aching, cramping, and abdominal discomfort.
- Supports comfortable movement and participation in daily activities.
- Helps improve overall comfort and quality of life during episodes of cramping pain.
- Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
- Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
- Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
- Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
- Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
- Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
- Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
- Divide your daily food intake into smaller, more frequent meals to reduce nausea.
- Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
- Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
- Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
- Use ginger (tea, ale, or candies) to help relieve nausea.
- Get adequate rest and also avoid strenuous activities that can worsen nausea.
- Talk to your doctor about taking anti-nausea medication if your nausea is severe.
- Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
- Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
- Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
- When standing up, do so slowly and carefully to avoid sudden dizziness.
- Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
- Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
- If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
- Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
- Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
- Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
- Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
- Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
- Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
- Rest well; get enough sleep.
- Eat a balanced diet and drink enough water.
- Manage stress with yoga and meditation.
- Limit alcohol and caffeine.
- Physical activities like walking or jogging might help boost energy and make you feel less tired.
- Tell your doctor immediately if you experience symptoms of Nervousness, such as anxiety, jitteriness, or an increased heart rate, after taking medication or adjusting your medication regimen.
- Your doctor may adjust your medication regimen to alleviate symptoms of Nervousness. This can include switching to a different medication, reducing the dosage, or temporarily stopping the medication. Your doctor may also recommend alternative techniques like relaxation, mindfulness meditation, or journaling. These techniques can help reduce anxiety and Nervousness.
- Practice stress-reducing techniques, such as deep breathing exercises, yoga, or journaling, to help manage Nervousness.
- Engage in regular physical activity, such as walking or jogging, to help reduce anxiety and improve mood.
- Your doctor may advise considering cognitive-behavioural therapy (CBT) or other forms of talk therapy to address underlying anxiety or Nervousness.
- You should maintain regular follow-up appointments with your doctor to monitor nervousness symptoms, adjust treatment plans as needed, and discuss any concerns or questions.
Directions for Use
- Take KOLIGESIC MF TABLET with food to avoid any stomach upset.
- It is advised to take KOLIGESIC MF TABLET once daily, or as directed by your doctor.
- Swallow KOLIGESIC MF TABLET as a whole with a glass of water.
- Do not crush, chew, or break it.
How KOLIGESIC MF TABLET Works
Alcohol
Unsafe
Avoid consumption of alcohol while taking KOLIGESIC MF TABLET as it may cause increased drowsiness. It can also increase the risk of stomach bleeding.
Pregnancy
Caution
Please consult your doctor if you are pregnant or if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.
Breast Feeding
Unsafe
It is not recommended to breastfeed while taking KOLIGESIC MF TABLET. Consult your doctor before taking KOLIGESIC MF TABLET if you are breastfeeding.
Driving
Caution
KOLIGESIC MF TABLET may cause drowsiness and dizziness. Do not drive or operate machinery unless you are alert.
Liver
Caution
Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.
Kidney
Unsafe
KOLIGESIC MF TABLET should not be used in patients with renal disease. Please consult your doctor if you have kidney impairment or any concerns regarding this.
Children
Unsafe
KOLIGESIC MF TABLET is not recommended for children as safety and effectiveness have not been established.
Heart
Unsafe
This medicine is contraindicated in cardiac patients due to its adverse effects.
Geriatrics
Caution
KOLIGESIC MF TABLET can be given in elderly patients with extreme caution and only if prescribed by the doctor.
What if I have taken an overdose of KOLIGESIC MF TABLET
Diet & Lifestyle Advise
- Stay hydrated: Drink plenty of water throughout the day to support normal digestion and prevent constipation, which can make abdominal cramps worse.
- Eat smaller meals: Opt for small, frequent meals rather than large, heavy ones to avoid putting excess pressure on your digestive system.
- Avoid trigger foods: Limit your intake of spicy, fatty, or highly processed foods, as well as caffeine and carbonated drinks, which can trigger painful muscle spasms in your gut.
- Use gentle heat therapy: Applying a warm hot-water bottle or heating pad to your lower abdomen can help relax tight uterine and abdominal muscles naturally.
- Engage in light movement: Gentle stretching or short, slow walks can help stimulate healthy digestion and reduce the severity of pelvic and menstrual cramps.

Have a query?
How Soon It Starts Working
The time required for KOLIGESIC MF TABLET to start to work: The time required for KOLIGESIC MF TABLET to start to work is 60 minutes after administration.
The time for which the effects of KOLIGESIC MF TABLET last: The effect of KOLIGESIC MF TABLET lasts for 6 to 8 hours.
What if you forget to take KOLIGESIC MF TABLET
Storage
Drug Warnings
- Inspect the medicine before use: Do not take KOLIGESIC MF TABLET if the blister pack is torn, damaged, or shows signs of tampering.
- Use caution during activities requiring alertness: KOLIGESIC MF TABLET may cause drowsiness, dizziness, or blurred vision. Avoid driving, operating machinery, or performing tasks that require clear vision until you know how the medicine affects you.
- Avoid taking other NSAIDs without medical advice: Do not use medicines such as ibuprofen, naproxen, or other NSAIDs while taking KOLIGESIC MF TABLET unless specifically advised by your doctor, as this may increase the risk of stomach irritation, ulcers, and bleeding.
- Monitor breathing if you have asthma: If you have a history of asthma, pay close attention to any changes in breathing and seek medical advice if you experience wheezing, shortness of breath, or worsening respiratory symptoms.
- Inform healthcare providers before procedures: Tell your doctor, dentist, or other healthcare professionals that you are taking KOLIGESIC MF TABLET before undergoing any medical, surgical, or dental procedure.
Drug-Drug Interactions
Drug-Drug Interaction Summary:
- Blood thinners (e.g., warfarin): Taking these medicines alongside KOLIGESIC MF TABLET may increase the risk of bleeding and bruising.
Other pain relievers (e.g., aspirin, ibuprofen): Combining these with KOLIGESIC MF TABLET may increase the risk of severe stomach irritation, ulcers, and bleeding. - Blood pressure medicines: KOLIGESIC MF TABLET may reduce the effectiveness of certain blood pressure-lowering medicines.
- Antacids: Taking antacids at the same time as KOLIGESIC MF TABLET may reduce its absorption and effectiveness. Follow your doctor's advice regarding dose timing.
Drug-Drug Interactions
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Co-administration of Potassium chloride with Koligesic Mf Tablet can increase the risk of stomach inflammation.
How to manage the interaction:
Taking Potassium chloride with Koligesic Mf Tablet is avoided as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden dizziness, vomiting (especially with blood), or tarry stools, consult the doctor immediately. Do not discontinue the medication without consulting a doctor.
Co-administration of Pramlintide with Koligesic Mf Tablet can increase the risk of stomach inflammation.
How to manage the interaction:
Taking Pramlintide with Koligesic Mf Tablet is avoided, please consult your doctor before taking it. Contact your doctor if you experience stomach pain, vomiting, tarry stools, or weakness. Do not discontinue the medication without consulting a doctor.
Coadministration of Ketorolac with Koligesic Mf Tablet can increase the risk or severity of stomach inflammation and ulcers.
How to manage the interaction:
Taking Ketorolac with Koligesic Mf Tablet is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, black tarry stools, coughing up or vomiting blood, stomach pain, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Co-administration of Meloxicamc with Koligesic Mf Tablet can increase the risk or severity of stomach inflammation.
How to manage the interaction:
Taking Meloxicamc with Koligesic Mf Tablet is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unusual bleeding or bruising, black tarry stools, coughing up or vomiting blood, stomach pain, and weakness, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Taking Potassium citrate with Koligesic Mf Tablet can increase the risk of stomach inflammation.
How to manage the interaction:
Taking Potassium citrate with Koligesic Mf Tablet is avoided, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, sudden dizziness, vomiting with blood, or tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
Co-administration of Flurbiprofen with Koligesic Mf Tablet can increase the risk or severity of gastric bleeding, ulceration, and rarely, perforation leading to serious blood loss.
How to manage the interaction:
Taking Flurbiprofen with Koligesic Mf Tablet can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of dizziness, unusual bleeding or bruising, tarry stools, coughing up or vomiting blood, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Coadministration of Rivaroxaban with Koligesic Mf Tablet can increase the risk or severity of gastric bleeding, ulceration, and rarely, perforation leading to serious blood loss.
How to manage the interaction:
Taking Rivaroxaban with Koligesic Mf Tablet can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Coadministration of Methotrexate with Koligesic Mf Tablet may increase the blood levels and side effects of Methotrexate.
How to manage the interaction:
Although there is a possible interaction between Methotrexate with Koligesic Mf Tablet, it can be taken if prescribed by your doctor. However, if you experience any symptoms such as appetite loss, joint pain or swelling, yellowing of the skin or eyes, dark urine, dizziness, or unusual bruising or bleeding, consult a doctor immediately. Do not stop using medications without a doctor's advice.
Coadministration of Deferasirox with Koligesic Mf Tablet can increase the risk or severity of gastric bleeding.
How to manage the interaction:
Taking Deferasirox with Koligesic Mf Tablet can result in an interaction, it can be taken if your doctor has advised it. However, if you experience increased or decreased urination, swelling, shortness of breath, muscle cramps, or weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Combining Dalteparin with Dicyclomine and mefenamic acid can increase the risk of bleeding complications.
How to manage the interaction:
Although Dalteparin with Dicyclomine and mefenamic acid can lead to an interaction, it can be taken if your doctor has suggested it. If you notice any signs like bleeding, swelling, weakness, or blood in your urine or stool, make sure to contact your doctor right away. Do not stop using any medications without talking to a doctor.
Drug-Food Interactions
Drug-Food Interaction Summary:
- Alcohol: Avoid consuming alcohol while taking KOLIGESIC MF TABLET, as it can increase the risk of stomach ulcers, bleeding, dizziness, and severe drowsiness.
Drug-Food Interactions
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Reference
- Drugs.com Clinical Review Team. Dicyclomine Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
- Drugs.com Clinical Review Team. Mefenamic Acid Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
- Mefenamic Acid and Dicyclomine Hydrochloride [Package Insert]. 2024. [Accessed on 24 Mar. 2024]Check here
- Mefenamic Acid and Dicyclomine Hydrochloride [Package Insert]. 2015. [Accessed on 14 Aug. 2024]Check here
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- Lelypharma B.V. Electronic Medicines Compendium (EMC). [Revised in April 2020] [Accessed on 25th February 2026]Check here



















