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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Kombina Suspension is used to treat bacterial infections of the urinary tract, respiratory tract (bronchitis), ear (otitis media), lungs (pneumonia), skin, brain and toxoplasmosis (infection caused by a bacteria called toxoplasma). It contains Trimethoprim and Sulfamethoxazole, which stop the growth of bacteria and kill them. Therefore, it helps treat bacterial infections. In some cases, you may experience specific common side effects, such as high levels of potassium in the blood, palpitations (abnormal heartbeats), thrush or candidiasis (fungal infection), headache, nausea, diarrhoea, and skin rashes. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Consume Type :

ORAL

Return Policy :

Not Returnable

About Kombina Suspension

Kombina Suspension is used to treat bacterial infections of the urinary tract, respiratory tract (bronchitis), ear (otitis media), lungs (pneumonia), skin, brain and toxoplasmosis (infection caused by a bacteria called toxoplasma). Bacterial infections are caused by the multiplication of harmful bacteria inside or on the body. Kombina Suspension does not work against infections caused by the virus, including cold and flu. 

Kombina Suspension combines two antibiotics: Trimethoprim (folic acid inhibitors) and Sulfamethoxazole (sulfonamides). Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. Tetrahydrofolic acid and dihydrofolic acid are essential for forming proteins and nucleic acids, which are necessary for the survival of the bacteria. By inhibiting these, Kombina Suspension stops the growth of bacteria and kills them. Therefore, it helps treat bacterial infections.

Your doctor will decide the dose and duration of Kombina Suspension based on your condition and the severity of the infection. In some cases, you may experience specific common side effects, such as high levels of potassium in the blood, palpitations (abnormal heartbeats), thrush or candidiasis (fungal infection), headache, nausea, diarrhoea, and skin rashes. Most of these side effects do not require medical attention and resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Before starting Kombina Suspension, please inform your doctor if you have any allergy (against any antibiotic), kidney or liver problems. Do not take Kombina Suspension on your own as self-medication may lead to antibiotic resistance in which antibiotics fail to act against specific bacterial infections. Consult your doctor before taking Kombina Suspension if you are pregnant or breastfeeding. Avoid alcohol consumption to prevent unpleasant side effects such as fast heartbeats, warmth or redness under your skin, tingly feeling, nausea, and vomiting. Kombina Suspension is not recommended for children below 12 years.

Uses of Kombina Suspension

Kombina Suspension is used to treat bacterial infections. The detailed uses of Kombina Suspension are as follows:<br/>•Urinary Tract Infections (UTIs): Kombina Suspension is often utilized to treat urinary tract infections caused by susceptible bacteria. It prevents bacterial growth and allows the immune system to eliminate the disease.<br/>•Respiratory Tract Infection: Kombina Suspension can be used to treat specific respiratory infections, including bronchitis and pneumonia, and prevent breathing difficulties caused by bacterial infection.<br/>•Gastrointestinal infections: Kombina Suspension is often helpful against gastrointestinal infections, especially those caused by Shigella or Salmonella strains. It reduces symptoms like diarrhea and abdominal pain.<br/>•Skin and Soft Tissue Infections: Kombina Suspension effectively treats bacterial skin infections such as infected cuts, burns, or surgical wounds.<br/>•Pneumocystis Pneumonia (PCP): Kombina Suspension prevents a potentially life-threatening condition in those with weakened immune systems.

Directions for Use

• Kombina Suspension can be taken with or without food as advised by your doctor.• Follow your doctor's instructions on the dosage and timing of this medication.• Swallow Kombina Suspension as a whole with a glass of water.• Do not crush, break, or chew it.

Medicinal Benefits

Kombina Suspension belongs to the group of medicines called ‘antibiotics’ used to treat various bacterial infections of the urinary tract, respiratory tract (bronchitis), ear (otitis media), lungs (pneumonia), skin, brain and toxoplasmosis (infection caused by a bacteria called toxoplasma). Kombina Suspension is a combination of two antibiotics: Trimethoprim (folic acid inhibitors) and Sulfamethoxazole (sulfonamides). Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. Tetrahydrofolic acid and dihydrofolic acid are essential for the formation of proteins and nucleic acids, which are necessary for the survival of the bacteria. By inhibiting these, Kombina Suspension kills the bacteria and stops their growth. Therefore, it helps treat bacterial infections. Kombina Suspension is a broad-spectrum antibiotic which is active against a wide range of gram-positive and gram-negative bacteria such as Streptococcus pneumonia, Escherichia coli, Klebsiella species, Enterobacter species, Haemophilus influenzae, etc.

How Kombina Suspension Works

Kombina Suspension is a combination of two antibiotics: Trimethoprim (folic acid inhibitors) and Sulfamethoxazole (sulfonamides). Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. Tetrahydrofolic acid and dihydrofolic acid are essential for the formation of proteins and nucleic acids, which are necessary for the survival of the bacteria. By inhibiting these, Kombina Suspension stops the growth of bacteria and kills them. Thereby, it helps to treat bacterial infections.

Storage

Keep Kombina Suspension out of reach and sight of children.

What if I have taken an overdose of Kombina Suspension

Do not take more than the prescribed dose of Kombina Suspension as it may cause overdose. The symptoms of overdose include headache, dizziness, nausea, vomiting, confusion, loss of appetite, drowsiness, or mental depression. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Kombina Suspension if you are allergic to any of its contents; if you have severe liver or kidney problems, thrombocytopenia (low levels of platelets in the blood), or porphyria (rare blood problem). Consult your doctor immediately if you experience skin rash or prolonged, significant diarrhoea with abdominal pain. Talk to your doctor before taking Kombina Suspension if you have severe allergies, asthma, ulcers, blood disorders, thyroid dysfunction, diabetes, are elderly, underweight or malnourished; if you have a folic acid deficiency, glucose-6-phosphate dehydrogenase deficiency, or high levels of potassium in the blood. Consult your doctor if you are pregnant or breastfeeding. Avoid alcohol consumption while taking Kombina Suspension to prevent unpleasant side-effects such as fast heartbeats, warmth or redness under your skin, tingly feeling, nausea, and vomiting.

Diet & Lifestyle Advise

  • Antibiotics can alter the useful bacteria in the stomach, which help in digestion. Therefore, you are advised to take foods rich in probiotics such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.
  • Eat fibre rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.
  • Avoid foods rich in calcium, grapefruit and grapefruit juice as they might hinder the absorption of antibiotics.
  • Avoid consumption of alcohol and usage of tobacco.

Habit Forming

No

Therapeutic Class

ANTIBIOTIC COMBINATION
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Alcohol

Unsafe

Avoid alcohol consumption while taking Kombina Suspension to prevent unpleasant side-effects such as fast heartbeats, warmth or redness under your skin, tingly feeling, nausea, and vomiting.

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Pregnancy

Caution

Please consult your doctor before taking Kombina Suspension if you are pregnant. Your doctor will prescribe Kombina Suspension only if the benefits outweigh the risks.

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Breast Feeding

Caution

Please consult your doctor if you are breastfeeding, your doctor will prescribe Kombina Suspension only if the benefits outweigh the risks.

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Driving

Caution

It is unknown whether Kombina Suspension affects your ability to drive and operating machinery. Drive only if you are physically stable and mentally focussed.

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Liver

Caution

Please consult your doctor before taking Kombina Suspension if you have liver impairment/liver disease. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Kidney

Caution

Kombina Suspension to be taken with caution, especially if you have a history of kidney impairment/kidney disease. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Kombina Suspension is not recommended for children below 12 years.

Have a query?

FAQs

Kombina Suspension is used to treat bacterial infections of the urinary tract, respiratory tract (bronchitis), ear (otitis media), lungs (pneumonia), skin, brain and toxoplasmosis (infection caused by a bacteria called toxoplasma).

Kombina Suspension is a combination of two antibiotics, namely: Trimethoprim (folic acid inhibitors) and Sulfamethoxazole (sulfonamides). Trimethoprim prevents the formation of tetrahydrofolic acid, and sulfamethoxazole stops the bacteria from making dihydrofolic acid. By inhibiting these, Kombina Suspension kills the bacteria and stops their growth. Thereby, helps to treat bacterial infections.

Kombina Suspension causes thrush or candidiasis, which is a fungal infection occurring due to the overgrowth of yeast-like fungus in the mouth or throat. Regularly rinse your mouth with water to prevent the growth of fungus.

Diarrhoea might be a side-effect of Kombina Suspension. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience prolonged diarrhoea with abdominal pain, stop taking Kombina Suspension and consult your doctor. Do not take anti-diarrheal medicine on your own.

It is recommended to complete the course of Kombina Suspension even if you feel better as it is an antibiotic, and leaving it in between may lead to recurring infections. Continue taking Kombina Suspension for as long as your doctor has prescribed to treat your condition effectually.

Do not take Kombina Suspension on your own as self-medication may lead to antibiotic-resistance in which antibiotics fail to act against specific bacterial infections.

Kombina Suspension may affect certain laboratory test results. Inform the person doing the tests that you are taking Kombina Suspension.

Kombina Suspension may cause high levels of potassium in the blood, which could lead to abnormal heartbeats (palpitations). Regular monitoring of potassium levels and heart rate is advised while taking Kombina Suspension.

You can take Kombina Suspension with or without as advised by your doctor. Take Kombina Suspension preferably with food to avoid nausea or diarrhoea.

No, Kombina Suspension is not an addiction causing medicine. But the dose and duration should be followed as prescribed by your doctor.

Yes, Kombina Suspension can be used for urinary tract infection as Kombina Suspension is used to prevent infections caused by bacteria.

Pimples are caused due to various reasons. Therefore, please consult your doctor before taking Kombina Suspension. If you have any concerns regarding acne, discuss with your doctor.

Yes, Kombina Suspension is a stronger antibiotic. It contains two antibiotics namely, Sulfamethoxazole and Trimethoprim.

Kombina Suspension can cause side effects such as high levels of potassium in your blood, which can cause abnormal heart beats. Also, it may cause fungal infections like thrush or candidiasis which can affect mouth or vagina and other common side effects like headache, nausea, diarrhoea and skin rashes. If these effects worsen or persist, consult your doctor.

Yes, Kombina Suspension is safe to use in most patients. However consult your doctor if you experience any side effects like nausea, vomiting, skin rash, allergic reaction.

Yes, Kombina Suspension can cause nausea and vomiting. If these persist or worsen, consult your doctor.

Kombina Suspension is contraindicated in patients who have a history of drug-induced immune thrombocytopenia from using trimethoprim and/or sulfonamides, who have a known hypersensitivity to these medications, or who have megaloblastic anemia from a folate deficiencies and in patients with severe renal insufficiency or obvious liver impairment.

Avoid spicy, acidic, and greasy foods while taking Kombina Suspension as they may increase your risk of side effects such upset stomach and diarrhoea. Also, Kombina Suspension can interact with alcohol. It's best to avoid drinking alcohol while taking Kombina Suspension.

Yes, Kombina Suspension expires. The expiry date can be found on the packaging.

No, do not stop taking Kombina Suspension without first consulting your doctor. Complete the full course of treatment even if you feel better as you may notice an improvement in your symptoms before the infection is cured completely.

If you miss a dose of Kombina Suspension, do not worry. Take it as soon as you remember. But, if it is time for your next dose, skip the missed dose and take your regular dose. Do not take a double dose to make up for the missed dose.

If you don't feel better after completing the full course of treatment with Kombina Suspension, inform your doctor. Also, let your doctor know if your symptoms are worsening while taking Kombina Suspension.

Kombina Suspension should be used in children above 12 years of age if advised by a doctor.

Avoid taking Kombina Suspension if you are allergic to Sulfamethoxazole, Trimethoprim or any other ingredients of Kombina Suspension. If you have severe liver or kidney problems, or have ever had thrombocytopenia (blood problem causing bleeding or bruises) or have porphyria (a rare blood problem), inform your doctor before taking Kombina Suspension.

Take Kombina Suspension as advised by your doctor. It should be taken with food and it must be taken at a fixed time to ensure better efficacy. Do not consume more than the recommended dose. Swallow it as whole with a glass of water. Do not crush or chew it.

Store the Kombina Suspension in the original package at room temperature. Keep it out of the reach and sight of children.

Country of origin

India

Manufacturer/Marketer address

no. 28 a- 1, 46th street, ashok nagar, chennai-600083, tamil nadu, india
Other Info - KO95729

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