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compositionComposition:CYPROTERONE-2MG+ETHINYLESTRADIOL-0.035MG
prescription
Prescription Medicine
info
Krimson 35 mg Tablet 21's
Krimson 35 mg Tablet 21's
Krimson 35 mg Tablet 21's

Krimson 35 mg Tablet contains Ethylestradiol and Cyproterone. It is used to treat moderate to severe acne related to androgen sensitivity and/or hirsutism (excess hair growth) in women of reproductive age. It works by blocking the production of androgens (male hormones) in the ovaries, thereby helping reduce acne and hair growth. In some cases, this medication may cause nausea, abdominal pain, headache, weight gain and mood changes. Before starting this medicine, inform your doctor if you are pregnant, breastfeeding, taking any other medicines or have pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CYPROTERONE-2MG+ETHINYLESTRADIOL-0.035MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Krimson 35 mg Tablet

Krimson 35 mg Tablet is an oral prescription medicine used primarily to treat skin and systemic conditions linked to hormone sensitivity, such as moderate to severe acne and excessive facial or body hair growth (hirsutism) in women. It is typically prescribed when other treatments, such as topical creams or oral antibiotics, have not worked. Because of how it works in the body, it also functions as an oral contraceptive, meaning you should not take other hormonal birth control pills alongside it.

For this medicine to work effectively, you must take it consistently at the same time every day. You can take Krimson 35 mg Tablet with or without food, though taking it with food or at bedtime may help if you experience mild nausea. Making simple lifestyle adjustments, such as maintaining a gentle skincare routine and eating a balanced diet, can support your treatment results.

Some women may experience mild side effects, including nausea, stomach ache, breast tenderness, or slight changes in body weight. While these are often temporary, you must contact your doctor immediately if you experience signs of serious conditions, such as severe leg pain, sudden chest pain, or difficulty breathing, which could indicate a blood clot.

Before taking Krimson 35 mg Tablet , tell your doctor if you have high blood pressure, diabetes, migraines, or a family history of blood clots. Do not take this medicine if you are pregnant, breastfeeding, or have a history of liver damage, unexplained vaginal bleeding, or blood circulation disorders.

This medication can interact with certain epilepsy drugs, tuberculosis treatments, and herbal remedies, which can make it less effective. Smoking while taking Krimson 35 mg Tablet significantly increases your risk of serious cardiovascular side effects, so avoiding tobacco is highly recommended. It is not intended for use in males, pregnant or breastfeeding individuals, or postmenopausal elderly women.

Uses of Krimson 35 mg Tablet

Krimson 35 mg Tablet is used to treat skin and systemic conditions due to hormone sensitivity. The detailed uses of Krimson 35 mg Tablet are as follows:

  • Severe Acne: Krimson 35 mg Tablet helps treat painful, deep, or inflammatory acne in women by lowering the level of male hormones (androgens) in the body, which reduces excess skin oil production.
  • Hirsutism (Excessive Hair Growth): Krimson 35 mg Tablet helps reduce coarse, dark, and unwanted facial or body hair growth in women by blocking the action of androgens at the hair follicles.
  • Polycystic Ovary Syndrome (PCOS) Symptoms: Krimson 35 mg Tablet helps manage symptoms of PCOS, such as irregular periods, acne, and excessive hair growth, by restoring a more balanced hormonal state.
     

Key Benefits

Krimson 35 mg Tablet helps manage hormone-related conditions by addressing the effects of excess androgen activity in the body. By helping restore hormonal balance, it can improve skin health, reduce unwanted hair growth, and support more regular menstrual cycles. This medicine offers several key benefits:

  • Supports Clearer and Healthier Skin: By targeting hormonal factors that contribute to acne, Krimson 35 mg Tablet helps reduce the formation of pimples, inflammatory lesions, and deep acne breakouts. This can improve skin appearance while reducing discomfort associated with acne-related inflammation.
  • Helps Reduce Unwanted Hair Growth: Krimson 35 mg Tablet may help decrease excessive facial and body hair growth associated with hormonal imbalances. With continued treatment, hair may become finer, softer, and less noticeable, reducing the need for frequent hair removal.
  • Promotes More Regular Menstrual Cycles: For individuals experiencing irregular periods due to hormonal disturbances, Krimson 35 mg Tablet can help establish a more predictable menstrual cycle. It may also contribute to lighter periods and reduced menstrual discomfort in some patients.
     

Directions for Use

To get the full benefit of Krimson 35 mg Tablet and minimise side effects, follow these simple guidelines:

  • Take Krimson 35 mg Tablet exactly as directed by your doctor.
  • Swallow the tablet whole with a glass of water. Do not chew, crush, or break the tablet.
  • Take this medicine at the same time each day to maintain a steady level of hormones in your body and ensure its effectiveness.
  • You can take Krimson 35 mg Tablet with or without food. If you experience mild nausea, taking it after a meal or before bed can help.
  • Always follow the specific instructions on your prescription pack, and do not stop taking this medication without consulting your doctor.
     

How Krimson 35 mg Tablet Works

Krimson 35 mg Tablet works through the combined action of two different hormonal components that target the root causes of hormone-related skin and hair issues. The first component is an anti-androgen. It works by blocking the effects of male hormones (androgens), which women naturally produce in small amounts. When these hormones are overactive, they overstimulate the oil glands in the skin and cause abnormal hair growth. By blocking them, this component reduces oiliness and slows down excess hair growth. The second component is a synthetic oestrogen. It supports this process by increasing the levels of a specific protein in the blood that binds to excess male hormones, making them inactive. Together, these two components regulate your hormone balance to clear your skin and manage unwanted hair.
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Alcohol

Consult your doctor

It is not known whether Krimson 35 mg Tablet interacts with alcohol. Please consult your doctor.

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Pregnancy

Unsafe

Krimson 35 mg Tablet is not recommended during pregnancy. Please consult the doctor if you are pregnant or think you may be pregnant.

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Breast Feeding

Unsafe

Krimson 35 mg Tablet is not recommended during lactation. Please consult the doctor if you are breastfeeding.

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Driving

Safe if prescribed

Krimson 35 mg Tablet is unlikely to affect your ability to drive.

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Liver

Caution

Krimson 35 mg Tablet may not be recommended for patients with severe liver disease. Please consult the doctor if you have liver problems.

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Kidney

Consult your doctor

Please consult the doctor if you have kidney problems.

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Children

Caution

Krimson 35 mg Tablet is not recommended for children. It is only indicated after menarche.

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Heart

Caution

Please inform your doctor if you have heart problems before taking Krimson 35 mg Tablet , as it may increase the risk of blood clots, stroke, or heart attack.

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Geriatrics

Caution

Please inform your doctor if you are geriatric before taking Krimson 35 mg Tablet , as age increases the risk of blood clots, stroke, or heart complications. A medical evaluation can help determine safer alternatives based on your health profile.

What if I have taken an overdose of Krimson 35 mg Tablet

Do not take more than the prescribed dose. It is unlikely that taking more than one pill will do you any harm, but you may feel sick, vomit or have some vaginal bleeding. Talk to your doctor if you have any of these symptoms.

Diet & Lifestyle Advise

  • Maintain a gentle skincare routine: Avoid harsh scrubs or squeezing acne lesions, as this can worsen inflammation. Use non-comedogenic (won't clog pores) skincare and makeup products.
  • Focus on a low-glycaemic diet: Eating whole grains, lean proteins, and plenty of vegetables can help regulate insulin levels, which is highly beneficial if you are managing PCOS-related symptoms.
  • Stay active: Regular physical activity helps improve insulin sensitivity, manage weight, and support overall hormonal balance.
  • Limit dairy and processed sugars: Some clinical evidence suggests that reducing high-glycaemic foods and excessive dairy intake can help reduce the frequency and severity of hormonal acne breakouts.
  • Protect your skin from the sun: Hormonal therapies can sometimes make your skin more sensitive to sunlight, increasing the risk of dark patches (chloasma). Apply a broad-spectrum sunscreen daily.
     

Health Queries

I have pcos in Jan 2026 after I got my period after 10 days I saw some light bleeding so I went to my gynac he prescribed krimson tablet and myo inositol after taking for a month i experience sleep disturbances there are many nights where I can't sleep at night bt during day I can sleep so I stopped after taking for a month bt again I saw some blood and large clots this time so I went to my gynac he again prescribed me krimson and told this is hormonal pill so there will be some disruption if my sleep disturbances persist for 2nd month too what should I do??

Bayyarapu Mahesh Kumar

Bayyarapu Mahesh Kumar

M Pharmacy

You have PCOS and were prescribed Krimson (a hormonal pill) and myo-inositol for irregular bleeding. It’s not uncommon for Krimson to cause hormonal changes that can affect sleep. Since you experienced night-time sleep disturbances during the first month, do not stop or restart the medication on your own. Continue taking it as prescribed, but contact your gynaecologist before starting the second month to discuss your sleep issues; they may adjust the treatment or suggest ways to manage your sleep. Keep a simple record of your bleeding and sleep patterns, and try to maintain a regular sleep schedule and healthy lifestyle to support your overall treatment.

Have a query?

How Soon It Starts Working

The time required for Krimson 35 mg Tablet to start to work: The time required for Krimson 35 mg Tablet to show its action is not clinically established.

The time for which the effects of Krimson 35 mg Tablet last: The duration of action for Krimson 35 mg Tablet is not clinically established.

What if you forget to take Krimson 35 mg Tablet

If you miss a dose of Krimson 35 mg Tablet , take it within the next 12 hours. If it has been more than 12 hours, skip the missed dose and take the next dose at the scheduled time.

Storage

•Store Krimson 35 mg Tablet at room temperature, ideally between 20°C and 25°C (68°F to 77°F). •Keep the tablets in their original blister packaging to protect them from moisture and direct light.

Drug Warnings

  • Watch for blood clot symptoms: This medication carries a small but serious risk of blood clots. Seek immediate medical care if you experience sudden chest pain, shortness of breath, or painful swelling in one leg.
  • Plan ahead for surgeries: If you are scheduled for a major surgery or will be immobilized for a long period, tell your doctor. You may need to stop taking Krimson 35 mg Tablet temporarily to reduce your risk of blood clots.
  • Do not use duplicate contraception: Krimson 35 mg Tablet acts as an oral contraceptive. Do not take other hormonal birth control pills, patches, or vaginal rings at the same time.
  • Attend regular health checkups: Your doctor will likely want to check your blood pressure, weight, and perform regular physical exams while you are taking this medication.
  • Do not share this medicine: This medication has been prescribed specifically for you based on your hormonal profile. Sharing it with others can be highly dangerous.
     

Drug-Drug Interactions

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Drug-Drug Interactions

  • Epilepsy and seizure medications (such as carbamazepine, phenytoin, or phenobarbital): These can speed up the removal of Krimson 35 mg Tablet from your body, making it less effective.
  • Certain antibiotics and tuberculosis medications (such as rifampicin): These can reduce the therapeutic effect and contraceptive protection of Krimson 35 mg Tablet .
  • Herbal supplements: Taking them can significantly lower the effectiveness of this medicine and lead to breakthrough bleeding.

Drug-Food Interactions

  • Grapefruit juice: Consuming large amounts of grapefruit juice may increase the concentration of hormones in your blood, potentially increasing the risk of side effects.

Drug-Disease Interactions

  • Circulatory and blood vessel disorders: Krimson 35 mg Tablet must not be used if you have a history of deep vein thrombosis, pulmonary embolism, heart attack, or stroke, as it can increase the risk of these conditions.
  • Liver disease: If you have active liver damage or a history of liver tumours, taking this medicine can worsen your condition.
  • Severe diabetes: If you have diabetes with damaged blood vessels, this medication can worsen circulation issues.
     
Ethinylestradiol + CyproteroneTranexamic acid
Critical
Ethinylestradiol + CyproteroneLetrozole
Severe

Drug-Drug Interactions

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Ethinylestradiol + CyproteroneTranexamic acid
Critical
How does the drug interact with Krimson 35 mg Tablet:
Coadministration of Tranexamic acid with Ethinylestradiol and Cyproterone may increase the risk of blood clot formation.

How to manage the interaction:
Taking Tranexamic acid with Ethinylestradiol and Cyproterone is avoided, as it can lead to an interaction, but can be taken if a doctor has prescribed it. However, if you suffer from chest discomfort, shortness of breath, blood in the urine, or swelling in your arms and legs, consult a doctor immediately. Do not stop using any medications without talking to a doctor.
Ethinylestradiol + CyproteroneLetrozole
Severe
How does the drug interact with Krimson 35 mg Tablet:
Coadministration of Letrozole with ethinyl estradiol + Cyproterone may reduce the levels of letrozole and make it less effective.

How to manage the interaction:
Although taking Letrozole with Krimson 35 mg Tablet can result in an interaction, it can be taken if a doctor has prescribed it. Do not stop using any medications without a doctor's advice.
Ethinylestradiol + CyproteroneOxcarbazepine
Severe
How does the drug interact with Krimson 35 mg Tablet:
Coadministration of Oxcarbazepine with Krimson 35 mg Tablet can reduce the blood levels of ethinylestradiol.

How to manage the interaction:
Although taking Oxcarbazepine with Krimson 35 mg Tablet can result in an interaction, it can be taken if a doctor has prescribed it. Contact your doctor if you experience any hot flashes, vaginal dryness, or irregular bleeding. Do not discontinue any medications without consulting a doctor.
Ethinylestradiol + CyproteroneTopiramate
Severe
How does the drug interact with Krimson 35 mg Tablet:
Co-administration of Topiramate with Ethinylestradiol and Cyproterone can reduce the levels and effects of Ethinylestradiol

How to manage the interaction:
Co-administration of Topiramate with Ethinylestradiol and Cyproterone can result in an interaction, it can be taken if a doctor has advised it. Contact your doctor if you experience any hot flashes, vaginal dryness, or irregular bleeding. Do not stop using any medications without a doctor's advice.
Ethinylestradiol + CyproteroneClindamycin
Severe
How does the drug interact with Krimson 35 mg Tablet:
Coadministration of Clindamycin with Ethinylestradiol and Cyproterone can reduce the effects of Clindamycin.

How to manage the interaction:
There may be a possibility of interaction between Clindamycin with Ethinylestradiol and Cyproterone, but it can be taken if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
Ethinylestradiol + CyproteroneMycophenolic acid
Severe
How does the drug interact with Krimson 35 mg Tablet:
Coadministration of Ethinylestradiol with Mycophenolic acid may lower the blood levels and effects of Ethinylestradiol, making it less effective as a form of birth control.

How to manage the interaction:
There could be a possible interaction between Mycophenolic acid and Ethinylestradiol, but they can be taken together if a doctor has prescribed them. Contact your doctor if you experience any hot flashes, vaginal dryness, or irregular bleeding. Do not discontinue any medications without a doctor's advice.
Ethinylestradiol + CyproteroneFosphenytoin
Severe
How does the drug interact with Krimson 35 mg Tablet:
Co-administration of Fosphenytoin with Krimson 35 mg Tablet may lower the blood levels and effects of Ethinylestradiol.

How to manage the interaction:
There may be a possibility of interaction of Fosphenytoin with Krimson 35 mg Tablet, it can be taken when prescribed by a doctor. If you use hormone replacement therapy for menopause, inform a doctor if your symptoms are no longer controlled or if you experience unusual bleeding. Do not stop using any medications without a doctor's advice.
Ethinylestradiol + CyproteronePrimidone
Severe
How does the drug interact with Krimson 35 mg Tablet:
Coadministration of Primidone with Krimson 35 mg Tablet may decrease the blood levels and effects of ethinylestradiol.

How to manage the interaction:
Although there is an interaction of Primidone with Krimson 35 mg Tablet, it can be taken if prescribed by a doctor. Contact your doctor if you experience any hot flashes, vaginal dryness, or irregular bleeding. Do not discontinue any medications without consulting a doctor.
Ethinylestradiol + CyproteroneCarfilzomib
Severe
How does the drug interact with Krimson 35 mg Tablet:
Coadministration of Carfilzomib with Ethinylestradiol and Cyproterone can increase the risk of developing blood clots.

How to manage the interaction:
There may be a possible interaction of Carfilzomib with Ethinylestradiol and Cyproterone but it can be taken if prescribed by a doctor. However, if you experience chest pain, shortness of breath, coughing up blood, swelling in arms and legs, or weakness, you should consult a doctor. Do not stop using any medications without a doctor's advice.
Ethinylestradiol + CyproteronePhenobarbital
Severe
How does the drug interact with Krimson 35 mg Tablet:
Coadministration of Phenobarbital with Krimson 35 mg Tablet can reduce the levels and effects of ethinylestradiol.

How to manage the interaction:
Although taking Phenobarbital with Krimson 35 mg Tablet can result in an interaction, it can be taken if a doctor has prescribed it. Contact your doctor if you experience any hot flashes, vaginal dryness, or irregular bleeding. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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FAQs

Krimson 35 mg Tablet is used to treat moderate to severe symptoms of PCOS, particularly androgen-sensitive acne and hirsutism (excess hair growth) in women of reproductive age. It works by reducing the effects of male hormones (androgens), which contribute to these symptoms.
Krimson 35 mg Tablet works by blocking the production of androgens (male hormones) in the ovaries.
Krimson 35 mg Tablet is also a hormonal contraceptive; it should not be used in combination with other hormonal contraceptives, as this will expose the patient to an excessive dose of hormones and is not necessary for effective contraception.
Krimson 35 mg Tablet does not protect against sexually transmitted diseases like HIV or Chlamydia. Only condoms can help do this.
Avoid using sunbeds or sunlamps and prolonged sunbathing whilst on treatment with Krimson 35 mg Tablet as it might increase the chance of chloasma (patchy discolouration of the skin).
Krimson 35 mg Tablet should be swallowed as a whole with water; do not crush or chew it. The dose will be determined by the doctor based on your condition.
If you miss a dose of Krimson 35 mg Tablet , take it within the next 12 hours. If it has been more than 12 hours, skip the missed dose and take the next dose at the scheduled time.
Repeat the dose if you have vomited within 3-4 hours of taking Krimson 35 mg Tablet . If it has been more than 4 hours, take the next dose at the scheduled time.
Yes, Krimson 35 mg Tablet works as an oral contraceptive by preventing ovulation and reducing the likelihood of pregnancy. However, it is prescribed primarily for women with PCOS who require treatment for androgen-related symptoms such as acne or excess hair growth, rather than solely for contraception.
Krimson 35 mg Tablet may cause nausea, abdominal pain, headache, weight gain and mood changes. Most of these side effects may not require medical attention and resolve gradually over time. However, you are advised to consult the doctor if the side effects persist or worsen.
Improvement in acne may begin within a few weeks of starting treatment. However, hormonal treatments generally require consistent use for several months, and it may take 3 to 6 months to experience the full benefits. Continue taking the medicine as prescribed and consult your doctor if you do not notice improvement after several months.
Some women may experience minor weight changes or fluid retention when they start taking Krimson 35 mg Tablet . This is usually temporary as your body adjusts to the hormones. If you notice rapid or significant weight gain, talk to your doctor.
Spotting or breakthrough bleeding between periods is common during the first few months of taking Krimson 35 mg Tablet . If the bleeding is heavy, lasts for more than a few days, or occurs after you have been taking the medicine for several months, talk to your doctor.
You should highly avoid smoking while taking Krimson 35 mg Tablet . Smoking significantly increases the risk of serious cardiovascular side effects, including blood clots, heart attacks, and strokes, particularly in women over the age of 35. Talk to your doctor for support with smoking cessation.
No, you must not take Krimson 35 mg Tablet if you are pregnant or planning to become pregnant. If you suspect you might be pregnant while taking this medication, stop taking it immediately and talk to your doctor.
While there is no direct interaction between alcohol and Krimson 35 mg Tablet , excessive alcohol intake can affect your liver function and may increase some side effects like headaches or nausea. It is always best to consume alcohol in moderation. Talk to your doctor if you have concerns about alcohol use.
You must inform your surgeon or doctor that you are taking Krimson 35 mg Tablet well in advance of any planned surgery. Because of the risk of blood clots during periods of inactivity, you may need to stop taking the medication several weeks before and after the procedure. Talk to your doctor to plan this safely.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Sun Pharmaceutical Industries Ltd., SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - KRI0001

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