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Larinate-200 Kit

Manufacturer/Marketer

Ipca Laboratories Ltd

Consume Type

ORAL

In Stock

Prescription Required
Product Details

About Larinate-200 Kit

Larinate-200 Kit belongs to a group of anti-malarial drugs used to treat uncomplicated falciparum malaria. Malaria is a mosquito-borne disease caused by the female anopheles mosquito. Malaria is transmitted through the bite of infected mosquitoes, which carry the Plasmodium parasite. The symptoms usually develop within 10 days to 4 weeks after the infection.
 
Larinate-200 Kit is a combination medicine that contains Artesunate, Pyrimethamine, and Sulphadoxine. Artesunate generates free radicals, thereby inhibiting nucleic acid and protein synthesis of the Plasmodium parasites during erythrocytic stages. Pyrimethamine binds to haem and forms a complex which is toxic to the malarial parasite. Sulphadoxine prevents the parasite from producing folinic acid, which is necessary for their multiplication. Together, Larinate-200 Kit helps in treating malaria.
 
Take Larinate-200 Kit with food. It is advised to take Larinate-200 Kit for as long as your doctor has prescribed, depending on your medical condition. In some cases, Larinate-200 Kit may cause nausea, vomiting, dizziness, abdominal pain, headache, diarrhoea, and fatigue. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Consult your doctor before taking Larinate-200 Kit if you are pregnant. Avoid breastfeeding while taking Larinate-200 Kit. Larinate-200 Kit may cause dizziness, so drive only if you are alert. Larinate-200 Kit should be given to children only if prescribed by the doctor. Avoid consuming alcohol along with Larinate-200 Kit as it could lead to increased dizziness. Keep your doctor informed about the medicines you take and your health condition to rule out any side effects.

Uses of Larinate-200 Kit

Malaria

Medicinal Benefits

Larinate-200 Kit is a combination medicine that contains Artesunate, Pyrimethamine, and Sulphadoxine. Larinate-200 Kit belongs to a group of medicines called anti-malarial drugs used to treat uncomplicated Plasmodium falciparum malaria. Artesunate is an anti-parasitic agent that generates free radicals, inhibiting nucleic acid and protein synthesis of the Plasmodium parasites during the erythrocytic stages. Pyrimethamine is an antiparasitic agent that binds to haem and forms a complex toxic to the malarial parasite. Sulphadoxine is an antibiotic that prevents the parasite from producing folinic acid, which is necessary for their multiplication. Together, Larinate-200 Kit helps in treating malaria.

Directions for Use

Take Larinate-200 Kit with food. Swallow Larinate-200 Kit as a whole with a glass of water; do not chew or crush the tablet. Your doctor will decide how long you need to take Larinate-200 Kit depending on your medical condition.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Larinate-200 Kit

  • Nausea 
  • Vomiting
  • Dizziness
  • Abdominal pain
  • Diarrhoea
  • Headache
  • Fatigue

In-Depth Precautions and Warning

Drug Warnings

Do not take Larinate-200 Kit if you are allergic to any of its contents. Inform your doctor before taking Larinate-200 Kit if you have epilepsy, asthma, blood problems, depression, schizophrenia, bipolar disorder, severe anxiety, glucose-6-phosphate dehydrogenase deficiency, stomach or intestinal infection, heart, kidney, or liver problems. Consult your doctor before taking Larinate-200 Kit if you are pregnant. Avoid breastfeeding while taking Larinate-200 Kit. Larinate-200 Kit may cause dizziness, so drive only if you are alert. Larinate-200 Kit should be given to children only if prescribed by the doctor. Avoid consuming alcohol along with Larinate-200 Kit as it could lead to increased dizziness. Consult your doctor immediately if you notice signs of infection, unusual tiredness, skin rash, unusual bleeding or bruising, red, swollen, or blistered skin.

Drug Interactions

Drug-Drug Interactions: Larinate-200 Kit may have interaction with anticonvulsant (carbamazepine, phenytoin), antiretroviral (ritonavir, nevirapine), antibiotics (rifampin), anti-malarial (chloroquine), antimetabolite (methotrexate).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Larinate-200 Kit may interact with depression, schizophrenia, bipolar disorder, seizure, colitis, and porphyria.

Drug-Drug Interactions Checker List:

  • CARBAMAZEPINE
  • PHENYTOIN
  • RITONAVIR
  • NEVIRAPINE
  • RIFAMPIN
  • CHLOROQUINE
  • METHOTREXATE
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      Avoid consumption of alcohol while taking Larinate-200 Kit as it may lead to increased dizziness.

    • Safety Warning

      Pregnancy

      caution

      Consult your doctor before taking Larinate-200 Kit if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

    • Safety Warning

      Breast Feeding

      unsafe

      Larinate-200 Kit passes into breastmilk. Avoid breastfeeding while taking Larinate-200 Kit.

    • Safety Warning

      Driving

      caution

      Larinate-200 Kit may cause dizziness. Do not drive or operate machinery unless you are alert.

    • Safety Warning

      Liver

      caution

      Larinate-200 Kit should be used with caution in patients with liver problems. Consult your doctor before taking Larinate-200 Kit if you have a liver impairment or any concerns regarding this.

    • Safety Warning

      Kidney

      caution

      Consult your doctor before taking Larinate-200 Kit if you have kidney impairment or any concerns regarding this.

    • Safety Warning

      Children

      caution

      Larinate-200 Kit should be given to children aged 6 months and older only if advised by the doctor.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Eat nutritious food containing proteins and vitamins.
    • Consume light and digestible foods such as soups, gruel, khichadi, and rice.
    • Drink plenty of fluids. It helps in preventing the formation of kidney stones.
    • Consume fruits rich in vitamin A and C, such as lemon, grapes, beetroot, and carrot.
    • Avoid high-fiber foods, fatty foods, junk foods, and caffeine.
    • Spray insecticides at home and outside to prevent mosquito breeding.
    • Cover your skin in areas that are abundant with mosquitoes. Use insect-repellent creams/spray.
    • Avoid pickles, alcohol, coffee, tea, carbonated beverages, and spicy food.

    Special Advise

    • Regular laboratory tests such as blood tests, liver and kidney function tests while taking Larinate-200 Kit are advised.

    Other Information (LAR0028)

    This item is Not Returnable.

    Expires on or after - Sep-23

    Patients Concern

    Disease/Condition Glossary

    Malaria: Malaria is a blood disease spread by the female anopheles mosquito. Malaria is spread through the bite of an infected mosquito carrying the Plasmodium parasite. The parasite is released into the bloodstream when an infected mosquito bites a person. The parasite develops in the liver before infecting red blood cells. It then multiplies in red blood cells, resulting in malarial infection. Malaria symptoms include fever, headache, exhaustion, muscle pain, back pain, chills, sweating, nausea, vomiting, and a dry cough. Symptoms typically appear 10 days to 4 weeks after infection.

    FAQs

    Larinate-200 Kit contains Artesunate, Pyrimethamine, and Sulphadoxine. Artesunate generates free radicals, inhibiting nucleic acid and protein synthesis of the Plasmodium parasites during erythrocytic stages. Pyrimethamine binds to haem and forms a complex which is toxic to the malarial parasite. Sulphadoxine prevents the parasite from producing folinic acid, which is necessary for their multiplication. Together, Larinate-200 Kit helps in treating malaria.

    Larinate-200 Kit might lower the number of platelets in the blood. This could lead to an increased risk of bleeding. Therefore, be cautious while using sharp objects. Inform your doctor if you notice blood in stools, black/tarry stools, or unusual bleeding or bruising.

    Larinate-200 Kit might lower blood glucose levels. Therefore, consult your doctor before taking Larinate-200 Kit if you are diabetic. To prevent any hypoglycaemic events, carry glucose, sugar, honey or candy. Regular monitoring of blood sugar levels whilst taking Larinate-200 Kit is advised.

    Larinate-200 Kit might cause increased sensitivity to the sun. Avoid exposure to sunlight and tanning beds. Wear a protective covering and SPF whilst going outside.

    Do not discontinue Larinate-200 Kit on your own as it might cause a relapse of the infection. To treat your condition effectually, continue taking Larinate-200 Kit for as long as your doctor has prescribed it. Do not be reluctant to speak with your doctor if your symptoms do not improve or if they become worse.

    Anticonvulsant drugs such as Carbamazepine and Phenytoin might lower the anti-malarial activity of Larinate-200 Kit. Therefore, consult a doctor before taking Larinate-200 Kit along with anticonvulsant drugs.

    Country Of Origin

    India

    Manufacturer/Marketer address

    142 AB, Kandivli Industrial Estate, Kandivli (West), Mumbai - 400 067, Maharashtra.

    Disclaimer

    While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

    (Inclusive of all taxes)

    Provide Delivery Location

    Strip

    1

    6 Tablet in 1 Strip