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  3. Larinate-200 Kit

Larinate-200 Kit, Pack of 1 TABLET
Larinate-200 Kit, Pack of 1 TABLET
Larinate-200 Kit, Pack of 1 TABLET
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Composition :

ARTESUNATE-200MG + PYRIMETHAMINE-25MG + SULPHADOXINE-500MG

Manufacturer/Marketer :

Ipca Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Larinate-200 Kit

Larinate-200 Kit belongs to a group of anti-malarial drugs used to treat uncomplicated falciparum malaria. Malaria is a mosquito-borne disease caused by the female anopheles mosquito. Malaria is transmitted through the bite of infected mosquitoes, which carry the Plasmodium parasite. The symptoms usually develop within 10 days to 4 weeks after the infection.
 
Larinate-200 Kit is a combination medicine that contains Artesunate, Pyrimethamine, and Sulphadoxine. Artesunate generates free radicals, thereby inhibiting nucleic acid and protein synthesis of the Plasmodium parasites during erythrocytic stages. Pyrimethamine binds to haem and forms a complex which is toxic to the malarial parasite. Sulphadoxine prevents the parasite from producing folinic acid, which is necessary for their multiplication. Together, Larinate-200 Kit helps in treating malaria.
 
Take Larinate-200 Kit with food. It is advised to take Larinate-200 Kit for as long as your doctor has prescribed, depending on your medical condition. In some cases, Larinate-200 Kit may cause nausea, vomiting, dizziness, abdominal pain, headache, diarrhoea, and fatigue. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Consult your doctor before taking Larinate-200 Kit if you are pregnant. Avoid breastfeeding while taking Larinate-200 Kit. Larinate-200 Kit may cause dizziness, so drive only if you are alert. Larinate-200 Kit should be given to children only if prescribed by the doctor. Avoid consuming alcohol along with Larinate-200 Kit as it could lead to increased dizziness. Keep your doctor informed about the medicines you take and your health condition to rule out any side effects.

Uses of Larinate-200 Kit

Treatment of Malaria

Directions for Use

• Take Larinate-200 Kit with food or as advised by your doctor.• It is advised to take Larinate-200 Kit once daily; however, follow your doctor's recommendation regarding the dosage and duration.• Swallow the medicine as a whole with a glass of water.• Do not crush, chew or break it.

Medicinal Benefits

Larinate-200 Kit is a combination medicine that contains Artesunate, Pyrimethamine, and Sulphadoxine. Larinate-200 Kit belongs to a group of medicines called anti-malarial drugs used to treat uncomplicated Plasmodium falciparum malaria. Artesunate is an anti-parasitic agent that generates free radicals, inhibiting nucleic acid and protein synthesis of the Plasmodium parasites during the erythrocytic stages. Pyrimethamine is an antiparasitic agent that binds to haem and forms a complex toxic to the malarial parasite. Sulphadoxine is an antibiotic that prevents the parasite from producing folinic acid, which is necessary for their multiplication. Together, Larinate-200 Kit helps in treating malaria.

How Larinate-200 Kit Works

Larinate-200 Kit is a combination medicine that contains Artesunate, Pyrimethamine, and Sulphadoxine. Artesunate generates free radicals, thereby inhibiting nucleic acid and protein synthesis of the Plasmodium parasites during erythrocytic stages. Pyrimethamine binds to haem and forms a complex which is toxic to the malarial parasite. Sulphadoxine prevents the parasite from producing folinic acid, which is necessary for their multiplication. Together, Larinate-200 Kit helps in treating malaria.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Larinate-200 Kit

Do not take more than the prescribed dose of Larinate-200 Kit as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Larinate-200 Kit if you are allergic to any of its contents. Inform your doctor before taking Larinate-200 Kit if you have epilepsy, asthma, blood problems, depression, schizophrenia, bipolar disorder, severe anxiety, glucose-6-phosphate dehydrogenase deficiency, stomach or intestinal infection, heart, kidney, or liver problems. Consult your doctor before taking Larinate-200 Kit if you are pregnant. Avoid breastfeeding while taking Larinate-200 Kit. Larinate-200 Kit may cause dizziness, so drive only if you are alert. Larinate-200 Kit should be given to children only if prescribed by the doctor. Avoid consuming alcohol along with Larinate-200 Kit as it could lead to increased dizziness. Consult your doctor immediately if you notice signs of infection, unusual tiredness, skin rash, unusual bleeding or bruising, red, swollen, or blistered skin.

Drug-Drug Interactions

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ArtesunateCabozantinib
Severe
ArtesunateEluxadoline
Severe

Drug-Drug Interactions

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ArtesunateCabozantinib
Severe
How does the drug interact with Larinate-200 Kit:
Taking Larinate-200 Kit with Cabozantinib may increase blood levels and effects of Larinate-200 Kit and increase the risk of side effects.

How to manage the interaction:
Although taking Larinate-200 Kit with cabozantinib together can result in an interaction, they can be taken if a doctor has prescribed it. Do not discontinue any medication without consulting a doctor.
ArtesunateEluxadoline
Severe
How does the drug interact with Larinate-200 Kit:
Taking Larinate-200 Kit with Eluxadoline may significantly increase the blood levels of eluxadoline. This may increase the risk and/or severity of side effects.

How to manage the interaction:
Although there is a possible interaction between Larinate-200 Kit and Eluxadoline, you can take these medicines together if prescribed by a doctor. However, if you experience persistent nausea, vomiting, drowsiness, constipation, stomach tenderness, and upper stomach pain, especially that which worsens after eating or radiates to the back or shoulders, contact a doctor immediately. Do not discontinue any medication without consulting a doctor.
ArtesunateAtazanavir
Moderate
How does the drug interact with Larinate-200 Kit:
Atazanavir may increase blood levels of Larinate-200 Kit and increase the risk of side effects such as liver damage, kidney failure, excess bilirubin in the blood, low red blood cell/platelet count and high white blood cell count.

How to manage the interaction:
If you are supposed to take Larinate-200 Kit and Atazanavir together, your doctor may adjust the dose or monitor more frequently to safely use both medications.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat nutritious food containing proteins and vitamins.
  • Consume light and digestible foods such as soups, gruel, khichadi, and rice.
  • Drink plenty of fluids. It helps in preventing the formation of kidney stones.
  • Consume fruits rich in vitamin A and C, such as lemon, grapes, beetroot, and carrot.
  • Avoid high-fiber foods, fatty foods, junk foods, and caffeine.
  • Spray insecticides at home and outside to prevent mosquito breeding.
  • Cover your skin in areas that are abundant with mosquitoes. Use insect-repellent creams/spray.
  • Avoid pickles, alcohol, coffee, tea, carbonated beverages, and spicy food.

Habit Forming

No

Therapeutic Class

ANTI- MALARIALS

Larinate-200 Kit Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Avoid consumption of alcohol while taking Larinate-200 Kit as it may lead to increased dizziness.

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Pregnancy

Caution

Consult your doctor before taking Larinate-200 Kit if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Larinate-200 Kit passes into breastmilk. Avoid breastfeeding while taking Larinate-200 Kit.

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Driving

Caution

Larinate-200 Kit may cause dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Larinate-200 Kit should be used with caution in patients with liver problems. Consult your doctor before taking Larinate-200 Kit if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Consult your doctor before taking Larinate-200 Kit if you have kidney impairment or any concerns regarding this.

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Children

Caution

Larinate-200 Kit should be given to children aged 6 months and older only if advised by the doctor.

Have a query?

FAQs

Larinate-200 Kit belongs to a group of anti-malarial drugs used to treat uncomplicated falciparum malaria.

Larinate-200 Kit contains Artesunate, Pyrimethamine, and Sulphadoxine. Artesunate generates free radicals, inhibiting nucleic acid and protein synthesis of the Plasmodium parasites during erythrocytic stages. Pyrimethamine binds to haem and forms a complex which is toxic to the malarial parasite. Sulphadoxine prevents the parasite from producing folinic acid, which is necessary for their multiplication. Together, Larinate-200 Kit helps in treating malaria.

Larinate-200 Kit might lower the number of platelets in the blood. This could lead to an increased risk of bleeding. Therefore, be cautious while using sharp objects. Inform your doctor if you notice blood in stools, black/tarry stools, or unusual bleeding or bruising.

Larinate-200 Kit might lower blood glucose levels. Therefore, consult your doctor before taking Larinate-200 Kit if you are diabetic. To prevent any hypoglycaemic events, carry glucose, sugar, honey or candy. Regular monitoring of blood sugar levels whilst taking Larinate-200 Kit is advised.

Larinate-200 Kit might cause increased sensitivity to the sun. Avoid exposure to sunlight and tanning beds. Wear a protective covering and SPF whilst going outside.

Do not discontinue Larinate-200 Kit on your own as it might cause a relapse of the infection. To treat your condition effectually, continue taking Larinate-200 Kit for as long as your doctor has prescribed it. Do not be reluctant to speak with your doctor if your symptoms do not improve or if they become worse.

Anticonvulsant drugs such as Carbamazepine and Phenytoin might lower the anti-malarial activity of Larinate-200 Kit. Therefore, consult a doctor before taking Larinate-200 Kit along with anticonvulsant drugs.

The common side effects of Larinate-200 Kit include nausea, vomiting, dizziness, abdominal pain, headache, diarrhoea, and fatigue. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

If you don't get better after using Larinate-200 Kit for the prescribed treatment period, please contact your doctor. They may need to adjust your treatment plan or check for other possible causes of your symptoms. Always follow your doctor's instructions and seek help if your symptoms get worse while using this medicine.

If you miss your dose, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and take your next dose at the regular time. Never take two doses at once to make up for a missed dose. If you are unsure, consult your doctor for guidance.

Country of origin

India

Manufacturer/Marketer address

142 AB, Kandivli Industrial Estate, Kandivli (West), Mumbai - 400 067, Maharashtra.
Other Info - LAR0028

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Veda MaddalaDoctor badge

Reviewed By

Veda Maddala

M Pharmacy

Last Updated

Jul 18, 2025 | 7:00 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://extranet.who.int/pqweb/sites/default/files/MA044part3v1.pdf
  2. https://www.drugs.com/mtm/pyrimethamine-and-sulfadoxine.html
  3. https://www.drugs.com/cdi/pyrimethamine-sulfadoxine.htm

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