Lefmaa-20Mg Tablet 10'S belongs to the group of medicines called 'anti-rheumatic agents' used to relieve symptoms of rheumatoid arthritis and psoriatic arthritis. Rheumatoid arthritis is an auto-immune disease (the body's immune system attacks its tissue) which leads to joint pain and damage. Psoriatic arthritis is a kind of inflammatory arthritis which occurs in patients with psoriasis (red patches of skin with silvery scales).
Lefmaa-20Mg Tablet 10'S contains 'Leflunomide' an isoxazole immunomodulatory agent which works by blocking the formation of genetic material, i.e. DNA required for survival of replicating (dividing) cells of the immune system. As a result, it suppresses the activated immune system to reduce pain, inflammation and swelling.
Take Lefmaa-20Mg Tablet 10'S at the same time every day as prescribed by your doctor. In some cases, Lefmaa-20Mg Tablet 10'S may cause common side-effects such as diarrhoea, nausea, stomach pain, indigestion, rash, and hair loss. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Do not take Lefmaa-20Mg Tablet 10'S if you are pregnant or planning for pregnancy as Lefmaa-20Mg Tablet 10'S may cause serious congenital disabilities. Lefmaa-20Mg Tablet 10'S should not be taken by breastfeeding mothers as it passes into breast milk. Lefmaa-20Mg Tablet 10'S may cause dizziness, so drive with caution. Avoid consuming alcohol along with Lefmaa-20Mg Tablet 10'S as it could lead to increased dizziness and liver damage. Lefmaa-20Mg Tablet 10'S may make you more susceptible to infections; consult your doctor if you develop any signs of infections such as fever, sore throat, breathlessness, jaundice, unexplained bleeding or bruising.
Uses of Lefmaa-20Mg Tablet 10'S
Rheumatoid arthritis, Psoriatic arthritis
Lefmaa-20Mg Tablet 10'S belongs to the group of medicines called anti-rheumatic agents used to relieve symptoms of rheumatoid arthritis and psoriatic arthritis. Lefmaa-20Mg Tablet 10'S is a disease-modifying antirheumatic drug (DMARDs) which inhibits an enzyme called dihydroorotate dehydrogenase and has antiproliferative activity (suppresses the cell growth). Thereby, helps in treating inflammation, redness, and swelling.
Directions for Use
Take Lefmaa-20Mg Tablet 10'S with or without food. Swallow Lefmaa-20Mg Tablet 10'S as a whole with water; do not crush or chew it.
Store in a cool and dry place away from sunlight
Side Effects of Lefmaa-20Mg Tablet 10'S
Do not take Lefmaa-20Mg Tablet 10'S if you are allergic to leflunomide, have severe liverkidney problems, low levels of protein in the blood, immune system problems, bone marrow problems, or serious infections. Lefmaa-20Mg Tablet 10'S is not recommended to be used in pregnant women, lactating mothers and people below 18 years of age. Talk to your doctor before taking Lefmaa-20Mg Tablet 10'S if you have/had serious infections like interstitial lung disease (inflammation of lungs), tuberculosis (TB), or pneumonia. Lefmaa-20Mg Tablet 10'S may cause dizziness, so drive with caution. Lefmaa-20Mg Tablet 10'S may make you more susceptible to infections; notify the doctor if you develop infections, sore throat, breathlessness, jaundice, unexplained bleeding or bruising.
Drug-Drug Interactions: Lefmaa-20Mg Tablet 10'S may interact with pain killers (ibuprofen, naproxen, acetaminophen, aspirin), anti-depressant (duloxetine), corticosteroids (prednisone), drugs used to treat arthritis (celecoxib, azathioprine, etanercept, adalimumab, meloxicam, methotrexate, abatacept, infliximab), and anti-malarial (hydroxychloroquine).
Drug-Food Interactions: Avoid consuming alcohol along with Lefmaa-20Mg Tablet 10'S as it could lead to liver damage.
Drug-Disease Interactions: Inform your doctor if you have low immunity, pneumonia, tuberculosis (TB), hypertension (high blood pressure), lung toxicity, peripheral neuropathy (nerve damage), liver and kidney dysfunction.
Drug-Drug Interactions Checker List
Diet & Lifestyle Advise
Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
Performing yoga may also help in improving joint flexibility and pain management.
Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
Acupuncture, massage and physical therapy may also be helpful.
Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
Avoid smoking and alcohol consumption.
Regular blood tests to monitor your liver function after starting Lefmaa-20Mg Tablet 10'S, and for every 6-8 weeks are advised.
Rheumatoid arthritis: It is an auto-immune disease (where the body's immune system attacks its tissue) which leads to joint pain and damage. Symptoms of rheumatoid arthritis include pain, inflammation of joints, difficulty in moving and swelling. Patients with rheumatoid arthritis have intense joint pain (especially knee joint) with stiffness.
Psoriatic arthritis: Psoriatic arthritis is an autoimmune disease characterized by inflammation of the skin (psoriasis) and joints (inflammatory arthritis). It mainly affects large joints in the lower extremities, distal joints of toes and fingers, back and pelvis. Symptoms include inflammation of joints, difficulty moving, swelling, patches of red, scaly skin and pain.
You are recommended to avoid alcohol consumption while taking Lefmaa-20Mg Tablet 10'S. Alcohol intake, along with Lefmaa-20Mg Tablet 10'S, may cause liver disease.
It is not recommended to take Lefmaa-20Mg Tablet 10'S while you are pregnant. Lefmaa-20Mg Tablet 10'S may cause serious birth defects.
It is not recommended to take Lefmaa-20Mg Tablet 10'S while you are breastfeeding. Lefmaa-20Mg Tablet 10'S passes into breast milk.
Lefmaa-20Mg Tablet 10'S may cause dizziness and tiredness; do not drive or operate heavy machinery if you feel dizzy.
Please consult your doctor if you have liver impairment before taking Lefmaa-20Mg Tablet 10'S.
Please consult your doctor if you have kidney impairment before taking Lefmaa-20Mg Tablet 10'S.
Lefmaa-20Mg Tablet 10'S is not approved for children under the age of 18 years.
How does Lefmaa-20Mg Tablet 10'S work?
Lefmaa-20Mg Tablet 10'S is a disease-modifying antirheumatic drug (DMARD) which stops DNA (genetic material) of the provoked immune system cells required for its survival. Thereby, helps in treating inflammation, redness, and swelling at the damaged site (especially joint).
Does Lefmaa-20Mg Tablet 10'S cause diarrhoea?
Lefmaa-20Mg Tablet 10'S may cause diarrhoea. Drink plenty of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea consult your doctor. Do not take anti-diarrheal medicine on your own.
How long does Lefmaa-20Mg Tablet 10'S take to work?
It might take 4-6 weeks before you notice any benefit. In some cases, it might also take 6 months for you to feel the full effect of Lefmaa-20Mg Tablet 10'S. Take Lefmaa-20Mg Tablet 10'S for as long as your doctor has prescribed to treat your condition effectually.
In which conditions should I avoid taking Lefmaa-20Mg Tablet 10'S?
Inform your doctor if you have liver disease, kidney disease, weak immune system and serious infections like pneumonia, or tuberculosis (TB).
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