Leucorin Tablet 10's
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About Leucorin Tablet
Leucorin Tablet is used in cancer treatment as an antidote to reduce the toxic effects of certain cancer drugs, such as methotrexate. It can also be used in combination with 5-fluorouracil in cancer treatment (cytotoxic therapy).
Leucorin Tablet contains calcium folinate, also known as Leucovorin, which is a form of vitamin B. It is folic acid in its active form. Leucorin Tablet works by preventing healthy cells from the toxic effects of methotrexate (cancer medicines) while accepting it to enter and kill the cancer cells. It should be administered as soon as possible after taking methotrexate.
Use Leucorin Tablet as advised by a qualified healthcare professional. You may experience nausea, diarrhoea, rash, vomiting, itching, urticaria or hives and stomatitis (oral mucositis). Most of these side effects of Leucorin Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist, contact your doctor.
Before taking the Leucorin Tablet , let your doctor know if you are allergic to any ingredient in it. Inform your doctor about your medical history and other medications you are currently taking to rule out any potential negative effects. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding or if you have pernicious anaemia or other forms of megaloblastic anaemia caused by vitamin B12 deficiency, GI toxicity, renal impairment and seizures.
Uses of Leucorin Tablet
Leucorin Tablet is used to prevent the harmful effects of methotrexate. The detailed uses of Leucorin Tablet are as follows:
- Protects healthy cells: Leucorin Tablet reduces the toxic side effects of methotrexate on normal, healthy tissues.
- Prevents folate deficiency: Leucorin Tablet restores folate levels that can be depleted by methotrexate treatment.
- Lowers risk of complications: Leucorin Tablet helps prevent mouth sores, low blood counts, and other side effects linked to methotrexate therapy.
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Directions for Use
- Leucorin Tablet can be taken with or without food as advised by the doctor.
- Follow your doctor’s instructions on the dosage and timing of this medication to ensure safety.
- Swallow Leucorin Tablet as a whole with a glass of water.
- Do not chew, crush, or break it.
Key Benefits
Leucorin Tablet belongs to the class of medicines known as detoxifying agents or folic acid analogues used in cytotoxic therapy as an antidote to reduce the toxicity and effect of certain cancer drugs such as methotrexate. Leucorin Tablet works by preventing healthy cells from the toxic effects of methotrexate (or other cancer medicines) while accepting it to enter and kill the cancer cells. Besides this, it can also use in combination with the drug 5-fluorouracil in cancer treatment (cytotoxic therapy).
How Leucorin Tablet Works
Storage
What if I have taken an overdose of Leucorin Tablet
Drug Warnings
Before taking the Leucorin Tablet , inform your doctor if you are allergic to any of its ingredients. If you are pregnant, planning to become pregnant, or breastfeeding, or if you have pernicious anaemia or other kinds of megaloblastic anaemia caused by vitamin B12 deficiency, GI toxicity, renal impairment, or seizures, please notify your doctor. Inform your doctor about your medical history and current drugs to rule out potential side effects.
Drug-Drug Interactions
Drug-Drug Interactions
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Co-administration of Leucorin Tablet with Trimethoprim may increase rates of treatment failure.
How to manage the interaction:
Although there is an interaction between Leucorin Tablet and trimethoprim, but it can be taken together if prescribed by the doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to your doctor.
Drug-Food Interactions
Drug-Food Interactions
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Diet & Lifestyle Advise
- Cancer can take a toll on anyone. Make sure you regularly see a therapist and take care of your mental health.
- Meditation and yoga have also proven very effective in helping cancer patients maintain a healthy attitude and body.
- Eat lean meats, healthy fats, fruits, vegetables and whole-grain foods to give you more energy.
- Stay hydrated by drinking plenty of water, as dehydration is often seen in cancers.
- Taking a stroll in the garden or spending 30 minutes doing some light physical activity can be very useful. However, do not overexert yourself if you feel too tired.
- Avoid taking Leucorin Tablet with alcohol as there may be an interaction.
- Avoid tobacco use.
Habit Forming
Therapeutic Class
Alcohol
Safe if prescribed
Avoid the consumption of alcohol as it may cause some side effects and make the effect of Leucorin Tablet less effective.
Pregnancy
Consult your doctor
Leucorin Tablet should not be used in pregnancy unless clearly necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Leucorin Tablet .
Breast Feeding
Consult your doctor
Leucorin Tablet should not be used in nursing mothers unless clearly necessary. So, inform your doctor if you are breastfeeding. Your doctor will weigh the benefits and potential risks before prescribing Leucorin Tablet .
Driving
Safe if prescribed
Leucorin Tablet does not affect your ability to drive or operate machinery.
Liver
Consult your doctor
If you have liver problems, inform your doctor before taking Leucorin Tablet . Your doctor may adjust the dose of this medicine based on your condition.
Kidney
Consult your doctor
If you have a pre-existing or a history of kidney condition, inform your doctor before taking Leucorin Tablet . Your doctor may adjust the dose of this medicine based on your condition.
Children
Safe if prescribed
Your doctor will weigh the benefits and potential risks before prescribing Leucorin Tablet .
Heart
If you have a heart disease or any related concerns, Please consult your doctor before using Leucorin Tablet .
Geriatrics
Consult your doctor
Leucorin Tablet should be given to geriatrics only when prescribed by a doctor. If you have any concerns about using Leucorin Tablet for geriatrics, please consult a doctor.
FAQs
Leucorin Tablet is used to prevent harmful effects of methotrexate.
Leucorin Tablet contains calcium folinate, also known as Leucovorin. Leucorin Tablet works by preventing healthy cells from the toxic effects of methotrexate (cancer medicines) while accepting it to enter and kill the cancer cells.
Leucorin Tablet is an antidote to the side effects of various chemotherapy medications, such as methotrexate.
Leucorin Tablet is contraindicated to use in populations with pernicious anaemia or other forms of megaloblastic anaemia caused by vitamin B12 deficiency.
It is contraindicated to use if you are known for hypersensitivity to any components present in Leucorin Tablet or if you have Pernicious anaemia or other anaemias due to vitamin B12 deficiency.
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Reference
- https://file.wuxuwang.com/hma/DE_H_2620_001_FinalPI_2of3.pdf
- https://medlineplus.gov/druginfo/meds/a682336.html
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/040347s010lbl.pdf
- https://news.cancerconnect.com/treatment-care/frequently-asked-questions-about-calcium-leucovorin-leucovorin
- https://www.drugs.com/drug-interactions/leucovorin.html
Recommended for a 30-day course: 2 Strips