Leucovis 7.5 mg Injection 2 ml

Prescription drug

MRP ₹150

(Inclusive of all Taxes)

₹22.5 Cashback (15%)

Written By Bayyarapu Mahesh Kumar , M Pharmacy

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Leucovis 7.5 mg Injection 2 ml is used in cancer treatment as an antidote to reduce the toxic effects of certain cancer drugs, such as methotrexate. It contains calcium folinate, also known as Leucovorin, which is a form of vitamin B. It is folic acid in its active form. It works by preventing healthy cells from the toxic effects of methotrexate (cancer medicines) while accepting it to enter and kill the cancer cells. It should be administered as soon as possible after taking methotrexate.

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About Leucovis 7.5 mg Injection 2 ml

Leucovis 7.5 mg Injection 2 ml is used in cancer treatment as an antidote to reduce the toxic effects of certain cancer drugs, such as methotrexate. It can also be used in combination with 5-fluorouracil in cancer treatment (cytotoxic therapy).

Leucovis 7.5 mg Injection 2 ml contains calcium folinate, also known as Leucovorin, which is a form of vitamin B. It is folic acid in its active form. Leucovis 7.5 mg Injection 2 ml works by preventing healthy cells from the toxic effects of methotrexate (cancer medicines) while accepting it to enter and kill the cancer cells. It should be administered as soon as possible after taking methotrexate.

Leucovis 7.5 mg Injection 2 ml will be administered by a qualified healthcare professional. You may experience nausea, diarrhoea, rash, vomiting, itching, urticaria or hives and stomatitis (oral mucositis). Most of these side effects of Leucovis 7.5 mg Injection 2 ml do not require medical attention and gradually resolve over time. However, if the side effects persist, contact your doctor.

Before taking the Leucovis 7.5 mg Injection 2 ml, let your doctor know if you are allergic to any ingredient in it. Inform your doctor about your medical history and other medications you are currently taking to rule out any potential negative effects. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding or if you have pernicious anaemia or other forms of megaloblastic anaemia caused by vitamin B12 deficiency, GI toxicity, renal impairment and seizures.

Uses of Leucovis 7.5 mg Injection 2 ml

Leucovis 7.5 mg Injection 2 ml is used for the prevention of harmful effects of methotrexate

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Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.• Leucovis 7.5 mg Injection 2 ml will be administered by the doctor or healthcare professional.• Do not self-administer.

Medicinal Benefits

Leucovis 7.5 mg Injection 2 ml belongs to the class of medicines known as detoxifying agents or folic acid analogues used in cytotoxic therapy as an antidote to reduce the toxicity and effect of certain cancer drugs such as methotrexate. Leucovis 7.5 mg Injection 2 ml works by preventing healthy cells from the toxic effects of methotrexate (or other cancer medicines) while accepting it to enter and kill the cancer cells. Besides this, it can also be used in combination with the drug 5-fluorouracil in cancer treatment (cytotoxic therapy).

How Leucovis 7.5 mg Injection 2 ml Works

Leucovis 7.5 mg Injection 2 ml contains calcium folinate, also known as Leucovorin, which is a form of vitamin B. It is folic acid in its active form. Leucovis 7.5 mg Injection 2 ml works by preventing healthy cells from the toxic effects of methotrexate (cancer medicines) while accepting it to enter and kill the cancer cells. It should be administered as soon as possible after taking methotrexate.

Storage

• Store in a cool and dry place away from sunlight.
• Keep Leucovis 7.5 mg Injection 2 ml out of the sight and reach of children.
• Non cold chain - To be stored in cool places at 10ÂºC to 25ÂºC or below 30ÂºC.

What if I have taken an overdose of Leucovis 7.5 mg Injection 2 ml

Since Leucovis 7.5 mg Injection 2 ml is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly.

Drug Warnings

Before taking the Leucovis 7.5 mg Injection 2 ml, inform your doctor if you are allergic to any of its ingredients. Also, if you are pregnant, planning to become pregnant, or breastfeeding, or if you have pernicious anaemia or other kinds of megaloblastic anaemia caused by vitamin B12 deficiency, GI toxicity, renal impairment, or seizures, please notify your doctor. Also, inform your doctor about your medical history and current drugs to rule out potential side effects.

Drug-Drug Interactions

Calcium folinateTrimethoprim

Severe

Drug-Drug Interactions

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Calcium folinateTrimethoprim

Severe

How does the drug interact with Leucovis 7.5 mg Injection 2 ml:
Co-administration of Leucovis 7.5 mg Injection 2 ml with Trimethoprim may increase rates of treatment failure.

How to manage the interaction:
Although there is an interaction between Leucovis 7.5 mg Injection 2 ml and trimethoprim, but it can be taken together if prescribed by the doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to your doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Cancer can take a toll on anyone. Make sure you regularly see a therapist and take care of your mental health.
Meditation and yoga have also proven very effective in helping cancer patients maintain a healthy attitude and body.
Eat lean meats, healthy fats, fruits, vegetables and whole-grain foods to give you more energy.
Stay hydrated by drinking plenty of water, as dehydration is often seen in cancers.
Taking a stroll in the garden or spending 30 minutes doing some light physical activity can be very useful. However, do not overexert yourself if you feel too tired.
Avoid taking Leucovis 7.5 mg Injection 2 ml with alcohol as there may be an interaction.
Avoid tobacco use.

Habit Forming

No

Therapeutic Class

DETOXIFYING AGENTS

Alcohol

Caution

Avoid the consumption of alcohol as it may cause some side effects and make the impact of Leucovis 7.5 mg Injection 2 ml less effective.

Pregnancy

Caution

Leucovis 7.5 mg Injection 2 ml should not be used when pregnancy unless clearly necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Leucovis 7.5 mg Injection 2 ml.

Breast Feeding

Caution

Leucovis 7.5 mg Injection 2 ml should not be used in nursing mothers unless clearly necessary. So, inform your doctor if you are a nursing mother. Your doctor will weigh the benefits and potential risks before prescribing Leucovis 7.5 mg Injection 2 ml.

Driving

Safe

Leucovis 7.5 mg Injection 2 ml does not affect the ability to drive or operate machinery.

Liver

Caution

Inform your doctor before receiving the Leucovis 7.5 mg Injection 2 ml if you have had a liver impairment/disorder history. Your doctor may adjust the dose of this medicine based on your condition.

Kidney

Caution

Inform your doctor before receiving the Leucovis 7.5 mg Injection 2 ml if you have had a kidney impairment/disorder history. Your doctor may adjust the dose of this medicine based on your condition.

Children

Safe if prescribed

Your doctor will weigh the benefits and potential risks before prescribing Leucovis 7.5 mg Injection 2 ml.

FAQs

What is the use of Leucovis 7.5 mg Injection 2 ml?

Leucovis 7.5 mg Injection 2 ml is used to prevent the harmful effects of methotrexate.

How does Leucovis 7.5 mg Injection 2 ml works?

Leucovis 7.5 mg Injection 2 ml contains calcium folinate, also known as Leucovorin. This compound prevents healthy cells from the toxic effects of methotrexate (cancer medicine) while accepting it to enter and kill cancer cells.

Is Leucovis 7.5 mg Injection 2 ml an antidote medication?

Leucovis 7.5 mg Injection 2 ml is an antidote to the side effects of various chemotherapy medications, such as methotrexate.

Is ideal to use Leucovis 7.5 mg Injection 2 ml in patients with vitamin B12 deficiency?

Leucovis 7.5 mg Injection 2 ml is contraindicated to use in populations with pernicious anaemia or other forms of megaloblastic anaemia caused by vitamin B12 deficiency.

In which conditions Leucovis 7.5 mg Injection 2 ml is not recommended not to use?

It is contraindicated to use if you are known for hypersensitivity to any components present in Leucovis 7.5 mg Injection 2 ml or if you have Pernicious anaemia or other anaemias due to vitamin B12 deficiency.

What is megaloblastic anemia?

Megaloblastic anemia is a condition where abnormal, oversized red blood cells form due to defective DNA production, typically from a lack of vitamin B12 or folate (folic acid). Symptoms include fatigue, pale skin, and sometimes neurological issues.

How long does it take for Leucovis 7.5 mg Injection 2 ml to work?

Leucovis 7.5 mg Injection 2 ml starts to act on the body within a few minutes of administration. It is not the same for everyone. It differs based on your health conditions, the dosage received, and the treatment recommended by your doctor.

What are some of the laboratory tests conducted before or during the treatment with Leucovis 7.5 mg Injection 2 ml?

Your doctor may recommend specific blood tests during your treatment with Leucovis 7.5 mg Injection 2 ml to check methotrexate levels especially if you are undergoing chemotherapy or in cases of overdose. A complete blood count (CBC) will also be done to check red blood cell levels if you are being treated for anemia and also calcium levels (to avoid hypercalcemia due to calcium in Leucovis 7.5 mg Injection 2 ml). These tests are essential for ensuring the treatment is both safe and effective.

What measures should be taken to ensure the prompt excretion of methotrexate during treatment with Leucovis 7.5 mg Injection 2 ml?

To promote the excretion of methotrexate during treatment with Leucovis 7.5 mg Injection 2 ml, increase fluid intake to maintain urine output above 2,500 mL/day for 12 hours before and 36 hours after methotrexate infusion. Ensure urine pH is above 7.0 before the infusion and avoid acidic substances. Measure blood methotrexate levels at 24, 48 and 72 hours after infusion.

Country of origin

India

Manufacturer/Marketer address

2, Mahakant, Ellisbridge, Ashram Road, Ahmedabad, Gujarat 380006

Other Info - LEU0145

Keep Refrigerated. Do not freeze.Prepaid payment required.

Author Details

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 9:23 AM IST

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Drug-Drug Interactions

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FAQs

What is the use of Leucovis 7.5 mg Injection 2 ml?

How does Leucovis 7.5 mg Injection 2 ml works?

Is Leucovis 7.5 mg Injection 2 ml an antidote medication?

Is ideal to use Leucovis 7.5 mg Injection 2 ml in patients with vitamin B12 deficiency?

In which conditions Leucovis 7.5 mg Injection 2 ml is not recommended not to use?

What is megaloblastic anemia?

How long does it take for Leucovis 7.5 mg Injection 2 ml to work?

What are some of the laboratory tests conducted before or during the treatment with Leucovis 7.5 mg Injection 2 ml?

What measures should be taken to ensure the prompt excretion of methotrexate during treatment with Leucovis 7.5 mg Injection 2 ml?

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