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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Levo-Anawin 0.25% Inj is used to reduce pain and discomfort during labour, surgery, dental treatment and other medical procedures. It contains Bupivacaine, which works by blocking the transmission of pain signals and numbing the area. In some cases, this medicine may cause side effects such as weakness, numbness or tingling, restlessness, drowsiness, headache, nausea and vomiting. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Whats That

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Synonym :

BUPIVACAINE HYDROCHLORIDE

Composition :

BUPIVACAINE-0.25%

Manufacturer/Marketer :

Neon Laboratories Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Levo-Anawin 0.25% Inj

Levo-Anawin 0.25% Inj belongs to the class of 'local anaesthetics', primarily used to reduce pain and discomfort during labour, surgery, dental treatment and other medical procedures. It produces local numbness and relieves pain. Levo-Anawin 0.25% Inj is given in the form of an epidural injection at the spinal cord to prevent pain during labour and Caesarean section. Pain is a symptom triggered by the nervous system, which causes uncomfortable sensations in the body. Pain may be dull or sharp, and it might be constant or intermittent. The tolerance level of pain might vary from person to person.

Levo-Anawin 0.25% Inj contains 'Bupivacaine' that belongs to the group of medicines called 'amide-type anaesthetics'. Bupivacaine is a numbing medication that blocks the transmission of pain signals in the pain area by acting on the nervous system and nerves. This blockage causes the loss of pain sensation and promotes temperature, touch, deep pressure and muscle control. Thus, Levo-Anawin 0.25% Inj helps in numbing the area and provides relief from pain.

Your doctor will decide the dose and duration based on the severity of your pain and response to treatment. Common side effects of Levo-Anawin 0.25% Inj include weakness, numbness or tingling, restlessness, drowsiness, tremors or shakiness, headache, blurred vision, irregular heartbeat, chills or shivering, back pain, nausea and vomiting. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Inform your doctor if you have liver, kidney or heart diseases, high or low blood pressure, excess fat in the body and breathing problems before starting Levo-Anawin 0.25% Inj. It is essential to let your doctor know if you are pregnant, planning to conceive or a breastfeeding mother before using Levo-Anawin 0.25% Inj. Levo-Anawin 0.25% Inj causes drowsiness, so do not drive until you are mentally alert. Avoid alcohol to further prevent the worsening of side effects like drowsiness. Levo-Anawin 0.25% Inj is not recommended for children less than one year of age.

Uses of Levo-Anawin 0.25% Inj

Levo-Anawin 0.25% Inj is used to relieve pain. The detailed uses of Levo-Anawin 0.25% Inj are as follows:<br/> • Surgical anaesthesia: Effectively numbs the surgical area, helping prevent pain during major or minor operations.<br/> • Labour pain relief: Administered as an epidural injection to ease pain during childbirth without affecting consciousness.<br/> • Dental procedures: Used to numb the mouth, gums, or jaw to ensure a pain-free dental treatment.<br/> • Minor surgeries: Provides localised numbness aiding minor surgeries.<br/>

Directions for Use

  • Levo-Anawin 0.25% Inj will be administered by the doctor or nurse in a healthcare setting.
  • Do not self-administer it.

Medicinal Benefits

Levo-Anawin 0.25% Inj contains 'Bupivacaine,' a local anaesthetic used to relieve pain and discomfort during labour, surgery, dental treatment and other medical procedures. It works by blocking the transmission of pain signals in the pain area by acting on the nervous system and nerves. This blockage causes the loss of pain sensation and promotes temperature, touch, deep pressure and muscle control. Thus, Levo-Anawin 0.25% Inj helps in numbing the localised area and provides relief from pain. Levo-Anawin 0.25% Inj, when injected as an epidural injection at the spinal cord, it prevents pain during labour and Caesarean section.

How Levo-Anawin 0.25% Inj Works

Levo-Anawin 0.25% Inj contains 'Bupivacaine' that belongs to the group of medicines called 'amide-type anaesthetics'. Bupivacaine is a numbing medication that blocks the transmission of pain signals in the pain area by acting on the nervous system and nerves. This blockage causes the loss of pain sensation and promotes temperature, touch, deep pressure and muscle control. Thus, Levo-Anawin 0.25% Inj helps in numbing the area and provides relief from pain.

Storage

• Store in a cool and dry place away from sunlight.• Keep Levo-Anawin 0.25% Inj out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Levo-Anawin 0.25% Inj

Since Levo-Anawin 0.25% Inj is administered by a healthcare professional, an overdose is unlikely to occur. However, seek medical attention if you experience any unusual symptoms.

Drug Warnings

Brief your medical history to the doctor if you have any liver, kidney or heart diseases, high or low blood pressure, excess fat in the body, breathing problems, excess fluid in womb during pregnancy (a condition called hydramnios), a tumour of the ovary, blood poisoning (septicaemia) and fluid around lungs before starting Levo-Anawin 0.25% Inj. Let your doctor know if you use any prescription and non-prescription medications, including vitamins and herbal supplements, before starting Levo-Anawin 0.25% Inj. Levo-Anawin 0.25% Inj may affect the foetus when used by a pregnant mother. It is also released into breast milk during breastfeeding. Please consult your doctor if you are pregnant, planning to conceive or a breastfeeding mother. Levo-Anawin 0.25% Inj causes dizziness and drowsiness, so do not drive until you are mentally alert. Avoid alcohol to prevent the worsening of side effects further. Levo-Anawin 0.25% Inj is not recommended in children younger than one year of age.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Levo-Anawin 0.25% Inj 20Ml:
Co-administration of Cyclophosphamide with Levo-Anawin 0.25% Inj 20Ml can increase the risk of methemoglobinemia (low level of oxygen in the blood).

How to manage the interaction:
Co-administration of Levo-Anawin 0.25% Inj 20Ml with Cyclophosphamide can possibly result in an interaction, but it can be taken if a doctor has advised it. Keep a close eye on any signs or symptoms of Methemoglobinemia. If you notice any of these symptoms like gray skin, feeling sick, headaches, dizziness, tiredness, or trouble breathing, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Levo-Anawin 0.25% Inj 20Ml:
Taking phenazopyridine with Levo-Anawin 0.25% Inj 20Ml can increase the risk of methemoglobinemia(a blood disorder in which too little oxygen is delivered to the cells).

How to manage the interaction:
Although there is a drug interaction between phenazopyridine and Levo-Anawin 0.25% Inj 20Ml but can be taken together if advised by a doctor. If experience nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, fast breathing, fast heartbeat, anxiety and confusion contact doctor immediately. Do not discontinue medications without consulting a doctor.
How does the drug interact with Levo-Anawin 0.25% Inj 20Ml:
Taking Rasburicase with Levo-Anawin 0.25% Inj 20Ml may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Co-administration of Rasburicase with Levo-Anawin 0.25% Inj 20Ml can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, tiredness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
How does the drug interact with Levo-Anawin 0.25% Inj 20Ml:
Taking Phenobarbital with Levo-Anawin 0.25% Inj 20Ml can increase the risk of methemoglobinemia (a condition in which the iron in the hemoglobin molecule is defective, making it unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although there is a possible interaction between Levo-Anawin 0.25% Inj 20Ml and Phenobarbital, you can take these medicines together if prescribed by a doctor. Seek immediate medical attention if they develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without talking to a doctor.
How does the drug interact with Levo-Anawin 0.25% Inj 20Ml:
Taking Chloroquine with Levo-Anawin 0.25% Inj 20Ml can increase the risk of methemoglobinemia( blood disorder that affects how red blood cells deliver oxygen throughout your body).

How to manage the interaction:
Co-administration of Levo-Anawin 0.25% Inj 20Ml with Chloroquine can possibly result in an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Levo-Anawin 0.25% Inj 20Ml:
Combining Nitrofurantoin with Levo-Anawin 0.25% Inj 20Ml can increase the risk of methemoglobinemia (a condition in which the iron in the hemoglobin molecule (the red blood pigment) is defective, making it unable to carry oxygen effectively to the tissues).

How to manage the interaction:
There may be a possibility of interaction between Nitrofurantoin and Levo-Anawin 0.25% Inj 20Ml, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact a doctor right away. These symptoms include a condition called methemoglobinemia, problems with your heart or lungs, your skin turning gray, feeling sick to your stomach, having a headache, feeling dizzy or lightheaded, being very tired, having trouble breathing, breathing quickly or not deeply enough, a fast heartbeat, feeling your heart pounding, feeling anxious or confused. Do not stop using any medications without a doctor's advice.
How does the drug interact with Levo-Anawin 0.25% Inj 20Ml:
Levo-Anawin 0.25% Inj 20Ml has the potential to cause methemoglobinemia (a rare disorder in which the iron in the haemoglobin molecule (the red blood pigment) is defective, preventing it from carrying oxygen to the tissues adequately). This risk increases when used with hydroxycarbamide, which may lead to methemoglobinemia. When taking these drugs, those who are extremely young (particularly newborns and babies), have heart or lung conditions, certain genetic predispositions, or have a glucose-6-phosphate dehydrogenase deficit may be more likely to develop methemoglobinemia.

How to manage the interaction:
Although taking hydroxycarbamide and Levo-Anawin 0.25% Inj 20Ml together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as grey discolouration of the skin, abnormal blood colouration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Levo-Anawin 0.25% Inj 20Ml:
Coadministration of Levo-Anawin 0.25% Inj 20Ml with Sulfasalazine can increase the risk of methemoglobinemia (a rare red blood cell disorder).

How to manage the interaction:
Taking Levo-Anawin 0.25% Inj 20Ml with Sulfasalazine together can result in an interaction, but it can be taken if your doctor has advised it. It is important to keep a close eye on any signs or symptoms of Methemoglobinemia. If you notice any of these symptoms like gray discoloration, nausea, headache, dizziness, fatigue, or shortness of breath, it's best to contact a doctor right away. They can help determine the cause and provide appropriate treatment. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Levo-Anawin 0.25% Inj 20Ml:
Coadministration of Levo-Anawin 0.25% Inj 20Ml and glyceryl trinitrate can increase the risk of developing methemoglobinemia (a rare condition where red blood cells are unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking Levo-Anawin 0.25% Inj 20Ml and glyceryl trinitrate together can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as grey discolouration of the skin, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Levo-Anawin 0.25% Inj 20Ml:
Taking Trimethoprim with Levo-Anawin 0.25% Inj 20Ml may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although there is a possible interaction between Levo-Anawin 0.25% Inj 20Ml and Trimethoprim, you can take these medicines together if prescribed by your doctor. However, if you experience nausea, headache, dizziness, fatigue, or difficulty breathing, it's best to contact your doctor right away. Do not stop using any medications without talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep, as resting the muscles can help in reducing inflammation and swelling.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

LOCAL ANESTHETICS
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Alcohol

Caution

You are recommended to limit or avoid alcohol consumption while taking Levo-Anawin 0.25% Inj. Alcohol intake, along with Levo-Anawin 0.25% Inj, may cause increased drowsiness.

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Pregnancy

Caution

Levo-Anawin 0.25% Inj is a pregnancy category C drug. Please consult your doctor before taking Levo-Anawin 0.25% Inj if you are pregnant or planning to conceive.

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Breast Feeding

Caution

Levo-Anawin 0.25% Inj is excreted into the breast milk. Please consult your doctor before taking Levo-Anawin 0.25% Inj if you are a nursing mother.

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Driving

Unsafe

Levo-Anawin 0.25% Inj may make you feel dizzy and drowsy that can affect your ability to drive. Do not drive or operate machinery if you experience these side effects.

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Liver

Caution

Please consult your doctor since Levo-Anawin 0.25% Inj should be used with caution in patients with liver impairment/liver disease.

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Kidney

Caution

Please consult your doctor since Levo-Anawin 0.25% Inj should be used with caution in patients with kidney impairment/kidney disease.

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Children

Caution

Levo-Anawin 0.25% Inj is not recommended in children, unless prescribed by a doctor.

Have a query?

FAQs

Levo-Anawin 0.25% Inj is used to induce anaesthesia to reduce pain and discomfort during labour, surgery, dental treatment and other medical procedures.

Levo-Anawin 0.25% Inj temporarily blocks the pain signals from the nerves of the painful area to the brain, thereby causing numbness at the affected site and providing relief from pain.

Levo-Anawin 0.25% Inj may affect your blood pressure. It is advised to inform your doctor before using Levo-Anawin 0.25% Inj if you have high blood pressure during pregnancy or low blood pressure.

You are recommended to consult your doctor to know the after-effects of Levo-Anawin 0.25% Inj if you are using an epidural injection of Levo-Anawin 0.25% Inj. Some epidural numbing medications may have long-lasting or permanent effects on body functions like bowel movement or bladder control, sexual function and movement in your legs. Please discuss the risks and benefits thoroughly with your doctor.

After using Levo-Anawin 0.25% Inj, you may not be able to move your body or the localised part for a certain time. You may feel numbness in the injected area. When you are injected with an epidural, you may not be able to move the lower part of your body for a certain period. It is advised to stay careful during such times to avoid any injuries. After a dental procedure with the usage of Levo-Anawin 0.25% Inj, please don't eat, chew gum or drink hot beverages until your mouth is completely free of numbness.

Levo-Anawin 0.25% Inj should be used with caution and only under doctor's supervision if you have any liver, kidney or heart diseases, high or low blood pressure, excess fat in the body, breathing problems, excess fluid in womb during pregnancy (a condition called hydramnios), a tumour of the ovary, blood poisoning (septicaemia) and fluid around lungs. Please let your doctor know if you suffer from any medical issues before using Levo-Anawin 0.25% Inj.

The common side effects of the Levo-Anawin 0.25% Inj may include weakness, numbness or tingling, restlessness, drowsiness, tremors or shakiness, headache, blurred vision, chills or shivering, back pain, nausea, and vomiting. However, these symptoms vanish as your body adjusts to the medication. If these symptoms become worse, please consult a doctor for relief.

Levo-Anawin 0.25% Inj contains Bupivacaine, which belongs to the group of medicines called amide-type anesthetics.

Pregnancy Category C means that animal studies have shown potential risks, but there are no good studies in pregnant women. As a result, the medication should only be used during pregnancy if the potential benefits justify the possible risks. Always consult your healthcare provider for personalized guidance.

Levo-Anawin 0.25% Inj is not an opioid or narcotic. It belongs to the class of local anesthetics. It primarily reduces pain and discomfort during surgery, dental treatments, and other medical procedures.

Levo-Anawin 0.25% Inj is a local anesthetic for numbing a specific area during surgeries or medical procedures. Depending on your condition, pain extent, and overall health, your doctor may combine it with other medications for optimal pain relief. Following your doctor's advice is best to avoid any potential interactions.

Both Ropivacaine and Levo-Anawin 0.25% Inj are safe and effective local anesthetics. Your doctor will prescribe the one most suitable for you based on your health status and the severity of your condition.

Early signs of local anesthesia toxicity can include symptoms like perioral numbness (numbness around the mouth), tinnitus (ringing in the ears), agitation, difficulty speaking (dysarthria), and confusion. These may be followed by more severe central nervous system (CNS) derangements such as seizures and coma.

Country of origin

India

Manufacturer/Marketer address

140, Damji Samji Industrial Complex, Mahakali Caves Rd., Andheri(East), Mumbai-93.
Other Info - LEV0918

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