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compositionComposition:LEVOBUPIVACAINE-5MG
prescriptionPrescription Medicine
Levo-Anawin 0.5% Injection 20 ml

Levo-Anawin 0.5% Injection is used to reduce pain and discomfort during medical procedures. Levo-Anawin 0.5% Injection contains Levobupivacaine as an active ingredient, which belongs to the group of medicines called 'amide-type anaesthetics'. It works by acting on the nervous system and nerves to block the transmission of pain signals in the pain area, which results in the loss of pain. Occasionally Levo-Anawin 0.5% Injection may cause side effects such as weakness, tingling, restlessness, drowsiness, headache, blurred vision, difficulty speaking, irregular heartbeat, chills or shivering, back pain, nausea and vomiting.

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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

LEVOBUPIVACAINE-5MG

Manufacturer/Marketer :

Neon Laboratories Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

Levo-Anawin 0.5% Injection is a local anaesthetic medicine used to reduce pain and discomfort during medical procedures. It produces local numbness and relieves pain. Pain is a symptom triggered by the nervous system, which causes uncomfortable sensations in the body. The tolerance level of pain might vary from person to person.

Levo-Anawin 0.5% Injection contains Levobupivacaine as an active ingredient, which belongs to the group of medicines called 'amide-type anaesthetics'. It works by acting on the nervous system and nerves to block the transmission of pain signals in the pain area, which results in the loss of pain.

Levo-Anawin 0.5% Injection may cause certain side effects such as weakness, tingling, restlessness, drowsiness, headache, blurred vision, difficulty speaking, irregular heartbeat, chills or shivering, back pain, nausea and vomiting. These side effects may not be similar to everyone and vary individually. If any of these side effects bother you, inform your doctor. Levo-Anawin 0.5% Injection will be administered by the doctor or the nurse before the surgery.

Inform your doctor if you have liver, kidney or heart diseases, high or low blood pressure, excess fat in the body and breathing problems before administering Levo-Anawin 0.5% Injection. This medicine is contraindicated in patients with severe hypotension, cardiogenic or hypovolaemic shock, the paracervical block in obstetrics and intravenous regional anaesthesia. Levo-Anawin 0.5% Injection is recommended for infiltration analgesia (ilioinguinal/iliohypogastric blocks) in children older than six months.

Uses of Levo-Anawin 0.5% Injection

Levo-Anawin 0.5% Injection is used for Surgical Anaesthesia and Pain Management. The detailed uses of Levo-Anawin 0.5% Injection are as follows:

  • Local and regional anaesthesia: Levo-Anawin 0.5% Injection is used to produce numbness in a specific area of the body during surgical or diagnostic procedures. It blocks nerve signals, allowing for pain-free operations without affecting consciousness.
  • Epidural anaesthesia during labour and cesarean section: Levo-Anawin 0.5% Injection is administered as an epidural injection to relieve labour pain or provide anaesthesia during C-sections. It helps manage pain while allowing the mother to remain awake and alert.
  • Postoperative pain management:Levo-Anawin 0.5% Injection is used to control pain after surgery by providing long-lasting local anaesthesia, reducing the need for systemic painkillers.
  • Dental and minor surgical procedures: Levo-Anawin 0.5% Injection is used to numb the area during dental work or minor outpatient surgeries, ensuring patient comfort without general anaesthesia.
  • Peripheral nerve blocks: Levo-Anawin 0.5% Injection is used to block sensation in a specific limb or region by targeting peripheral nerves, often used in orthopaedic or trauma-related procedures.

Key Benefits

Levo-Anawin 0.5% Injection contains Levobupivacaine, used to relieve pain and discomfort during labour, surgery, dental treatment and other medical procedures. It works by blocking the transmission of pain signals in the pain area by acting on the nervous system and nerves. This blockage causes the loss of pain sensation helps in numbing the localized area, and provides relief from pain. Levo-Anawin 0.5% Injection is injected as an epidural injection at the spinal cord during labour and Caesarean section to prevent labour pain.

Side effects of Levo-Anawin 0.5% Injection 20 ml

Directions for Use

  • Levo-Anawin 0.5% Injection is administered the doctor or healthcare professional.
  • Do not self-administer it.
Levo-Anawin 0.5% Injection contains Levobupivacaine as an active ingredient, which belongs to the group of medicines called 'amide-type anaesthetics'. It works by acting on the nervous system and nerves to block the transmission of pain signals in the pain area, which results in the loss of pain.
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Alcohol

Unsafe

Avoid alcohol consumption as it may cause increased drowsiness.

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Pregnancy

Caution

Levo-Anawin 0.5% Injection may be unsafe to use during pregnancy as it may show harmful effects on the foetus. Please consult your doctor before receiving Levo-Anawin 0.5% Injection if you are pregnant or planning to conceive.

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Breast Feeding

Safe if prescribed

Levo-Anawin 0.5% Injection passes into breastmilk. Hence, if you are breastfeeding, inform your doctor before receiving Levo-Anawin 0.5% Injection. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Caution

Levo-Anawin 0.5% Injection will be administered before surgical procedures.

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Liver

Caution

Patients with hepatic disease should use Amide local anaesthetics, like levobupivacaine, with caution, as the liver metabolizes these drugs. Individuals who suffer from severe liver disease are more susceptible to toxic plasma concentrations due to their impaired ability to metabolize local anaesthetics safely.

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Kidney

Consult your doctor

Limited information is available on the use of Levo-Anawin 0.5% Injection in patients with kidney problems. Hence, If you have a pre-existing or a history of kidney disease, inform your doctor before receiving Levo-Anawin 0.5% Injection.

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Children

Consult your doctor

Levo-Anawin 0.5% Injection is recommended for infiltration analgesia (ilioinguinal/iliohypogastric blocks) in children older than six months. Consult your doctor for more information.

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Heart

Caution

Levo-Anawin 0.5% Injection should be used with caution in patients with heart problems, as it may cause bradycardia, hypotension, or even cardiac arrest in rare cases. Always consult your doctor to assess risks and determine if it's safe for your condition.

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Geriatrics

Caution

Levo-Anawin 0.5% Injection can be used in geriatric patients, but age-related changes in heart, liver, or kidney function may increase sensitivity to its effects. Doctors usually adjust the dose and monitor closely to minimize risks like low blood pressure or prolonged numbness.

Since Levo-Anawin 0.5% Injection is given in a controlled medical setting by an experienced healthcare professional, an overdose is not likely to occur. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away.

Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle exercises like 20-30 minutes of walking or swimming would be helpful.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep, as resting the muscles can help in reducing inflammation and swelling.
  • Follow heat or cold therapy, and apply a cold or hot compress on the painful areas for 15-20 minutes regularly.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

Have a query?

Drug Warnings

Inform your doctor if you have liver, kidney or heart diseases, high or low blood pressure, excess fat in the body and breathing problems before starting Levo-Anawin 0.5% Injection. This medicine is contraindicated in patients with severe hypotension, such as cardiogenic or hypovolemic shock, for use in the paracervical block in obstetrics and for intravenous regional anaesthesia. Levo-Anawin 0.5% Injection is not recommended for children 12 years of age. Let your doctor know about your complete medical and medication history, including prescription and non-prescription medications, vitamins and herbal supplements, before starting Levo-Anawin 0.5% Injection. Levo-Anawin 0.5% Injection released into breast milk during breastfeeding. Please inform your doctor if you are pregnant, planning to conceive or a breastfeeding mother. Avoid alcohol to prevent the worsening of side effects further.

Drug-Drug Interactions

verifiedApollotooltip
LevobupivacainePhenazopyridine
Severe
LevobupivacaineTrimethoprim
Severe

Drug-Drug Interactions

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LevobupivacainePhenazopyridine
Severe
How does the drug interact with Levo-Anawin 0.5% Injection 20 ml:
Taking phenazopyridine with Levo-Anawin 0.5% Injection 20 ml can increase the risk of methemoglobinemia(a blood disorder in which too little oxygen is delivered to the cells).

How to manage the interaction:
Although there is a drug interaction between phenazopyridine and Levo-Anawin 0.5% Injection 20 ml but can be taken together if advised by a doctor. If experience nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, fast breathing, fast heartbeat, anxiety and confusion contact doctor immediately. Do not discontinue medications without consulting a doctor.
LevobupivacaineTrimethoprim
Severe
How does the drug interact with Levo-Anawin 0.5% Injection 20 ml:
Taking Trimethoprim with Levo-Anawin 0.5% Injection 20 ml may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although there is a possible interaction between Levo-Anawin 0.5% Injection 20 ml and Trimethoprim, you can take these medicines together if prescribed by your doctor. However, if you experience nausea, headache, dizziness, fatigue, or difficulty breathing, it's best to contact your doctor right away. Do not stop using any medications without talking to your doctor.
LevobupivacaineCyclophosphamide
Severe
How does the drug interact with Levo-Anawin 0.5% Injection 20 ml:
Co-administration of Cyclophosphamide with Levo-Anawin 0.5% Injection 20 ml can increase the risk of methemoglobinemia (low level of oxygen in the blood).

How to manage the interaction:
Co-administration of Levo-Anawin 0.5% Injection 20 ml with Cyclophosphamide can possibly result in an interaction, but it can be taken if a doctor has advised it. Keep a close eye on any signs or symptoms of Methemoglobinemia. If you notice any of these symptoms like gray skin, feeling sick, headaches, dizziness, tiredness, or trouble breathing, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
LevobupivacaineNitrofurantoin
Severe
How does the drug interact with Levo-Anawin 0.5% Injection 20 ml:
Combining Nitrofurantoin with Levo-Anawin 0.5% Injection 20 ml can increase the risk of methemoglobinemia (a condition in which the iron in the hemoglobin molecule (the red blood pigment) is defective, making it unable to carry oxygen effectively to the tissues).

How to manage the interaction:
There may be a possibility of interaction between Nitrofurantoin and Levo-Anawin 0.5% Injection 20 ml, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact a doctor right away. These symptoms include a condition called methemoglobinemia, problems with your heart or lungs, your skin turning gray, feeling sick to your stomach, having a headache, feeling dizzy or lightheaded, being very tired, having trouble breathing, breathing quickly or not deeply enough, a fast heartbeat, feeling your heart pounding, feeling anxious or confused. Do not stop using any medications without a doctor's advice.
LevobupivacaineHydroxycarbamide
Severe
How does the drug interact with Levo-Anawin 0.5% Injection 20 ml:
Levo-Anawin 0.5% Injection 20 ml has the potential to cause methemoglobinemia (a rare disorder in which the iron in the haemoglobin molecule (the red blood pigment) is defective, preventing it from carrying oxygen to the tissues adequately). This risk increases when used with hydroxycarbamide, which may lead to methemoglobinemia. When taking these drugs, those who are extremely young (particularly newborns and babies), have heart or lung conditions, certain genetic predispositions, or have a glucose-6-phosphate dehydrogenase deficit may be more likely to develop methemoglobinemia.

How to manage the interaction:
Although taking hydroxycarbamide and Levo-Anawin 0.5% Injection 20 ml together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as grey discolouration of the skin, abnormal blood colouration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
LevobupivacaineNitroprusside
Severe
How does the drug interact with Levo-Anawin 0.5% Injection 20 ml:
Co-administration of Levo-Anawin 0.5% Injection 20 ml and Nitroprusside can rarely cause methemoglobinemia(a condition that can reduce oxygen-carrying capacity of the blood).

How to manage the interaction:
Co-administration of Levo-Anawin 0.5% Injection 20 ml and Nitroprusside can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like grey discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
LevobupivacaineDapsone
Severe
How does the drug interact with Levo-Anawin 0.5% Injection 20 ml:
Taking Dapsone with Levo-Anawin 0.5% Injection 20 ml can increase the risk of methemoglobinemia (A condition in which the iron in the hemoglobin molecule is defective, making it unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although there is a possible interaction between Dapsone and Levo-Anawin 0.5% Injection 20 ml, you can take these medicines together if prescribed by a doctor. However, contact a doctor immediately if you experience headache, dizziness, shortness of breath, or a rapid heartbeat. Do not stop using any medications without consulting a doctor.
LevobupivacaineChloroquine
Severe
How does the drug interact with Levo-Anawin 0.5% Injection 20 ml:
Taking Chloroquine with Levo-Anawin 0.5% Injection 20 ml can increase the risk of methemoglobinemia( blood disorder that affects how red blood cells deliver oxygen throughout your body).

How to manage the interaction:
Co-administration of Levo-Anawin 0.5% Injection 20 ml with Chloroquine can possibly result in an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not discontinue any medications without consulting a doctor.
LevobupivacaineIsosorbide dinitrate
Severe
How does the drug interact with Levo-Anawin 0.5% Injection 20 ml:
Taking isosorbide dinitrate with Levo-Anawin 0.5% Injection 20 ml may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking isosorbide dinitrate and Levo-Anawin 0.5% Injection 20 ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
LevobupivacaineRasburicase
Severe
How does the drug interact with Levo-Anawin 0.5% Injection 20 ml:
Taking Rasburicase with Levo-Anawin 0.5% Injection 20 ml may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Co-administration of Rasburicase with Levo-Anawin 0.5% Injection 20 ml can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, tiredness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

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[LOCAL ANESTHETICS]

FAQs

Levo-Anawin 0.5% Injection is used for Surgical Anaesthesia and Pain Management.

Levo-Anawin 0.5% Injection temporarily blocks the pain signals from the nerves of the painful area to the brain, causing numbness at the affected site and relieving pain.

Levo-Anawin 0.5% Injection may affect your blood pressure. It is advised to inform your doctor before using Levo-Anawin 0.5% Injection if you have high blood pressure during pregnancy or low blood pressure.

In addition to Levo-Anawin 0.5% Injection, your doctor may prescribe certain other medications to help with pain management. This may help you get quick results and make you less prone to the side effects of other pain-relieving medicines.

No, you should not take Levo-Anawin 0.5% Injection on your own; it should be used only if prescribed by the doctor. Levo-Anawin 0.5% Injection is a local anaesthetic that requires administration by a qualified healthcare professional. Do not self-administer Levo-Anawin 0.5% Injection.

Levo-Anawin 0.5% Injection contains levobupivacaine as an active ingredient, which belongs to the group of medicines called amide-type anaesthetics.

No, it is not an opioid or narcotic. Levo-Anawin 0.5% Injection is a local anaesthetic.

In some cases, your doctor may prescribe other medicines in addition to Levo-Anawin 0.5% Injection for pain relief. However, consult your doctor before taking other medicines in addition to Levo-Anawin 0.5% Injection.

Ropivacaine might be safer than Levo-Anawin 0.5% Injection as it is less toxic to the heart compared to levobupivacaine. However, the doctor will prescribe which drug is safe for you based on your condition.

Seizures, airway problems, cardiac arrhythmias, and hypotension are the symptoms of local anaesthesia toxicity. If you experience any of these symptoms, consult your doctor immediately.

The common side effects of Levo-Anawin 0.5% Injection include weakness, tingling, restlessness, drowsiness, headache, blurred vision, difficulty speaking, irregular heartbeat, chills or shivering, back pain, nausea and vomiting. These side effects may not be similar to everyone and vary individually. If any of these side effects bother you, inform your doctor.

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

  • Dr Aneela Siddabathuni

    MPharma., PhD

Last Updated

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