Buy Loette Tablet online | Uses, Side Effects, Price and substitutes

Select Delivery Location

Composition:ETHINYLESTRADIOL-0.02MG+LEVONORGESTREL-0.1MG

Prescription Medicine

Loette Tablet is used for contraception and treating dysmenorrhea (irregular and painful periods). It contains Ethinylestradiol and Levonorgestrel, which maintains a normal menstrual cycle (periods) in women. It works by fulfilling the deficiency of estrogen hormone, thereby preventing symptoms like night sweats, hot flashes, and mood swings. Also, it prevents the release of an egg from the ovary (female reproductive cells) or prevents fertilization of an egg by sperm (male reproductive cells). It may also change the lining of the uterus to prevent the development of a pregnancy. It may cause side effects such as stomach pain, headache, nausea, breast pain, weight gain, and irregular uterine bleeding. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

Written By Lakshmithulasi Yarragunta , PharmD (PB)

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Offers & Discounts

Get Free delivery (₹99) with

Join Circle

Get Extra 18% Off with Coupons

Extra 10% Off with Bank Offers

More about the Product

Composition :

ETHINYLESTRADIOL-0.02MG+LEVONORGESTREL-0.1MG

Manufacturer/Marketer :

Pfizer Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Loette Tablet

Loette Tablet is an oral prescription medication primarily used to prevent pregnancy. It is a combined hormonal pill that helps women manage family planning reliably. Additionally, healthcare providers may prescribe it to regulate menstrual cycles and manage heavy or painful periods.

For maximum effectiveness, you must take this tablet once daily at the exact same time every day without fail. You can take it with or without food, though taking it with your evening meal or at bedtime may help reduce mild stomach upset. Maintaining a consistent routine is crucial to ensuring its protective effects.

While taking Loette Tablet , you may notice mild side effects like temporary nausea, breast tenderness, or light spotting between your periods. These usually resolve as your body adjusts to the hormones. However, you should contact your doctor immediately if you experience severe symptoms, such as sudden chest pain, severe headaches, or swelling and warmth in one of your legs.

Do not take this if you have a history of blood clots, active liver damage, uncontrolled high blood pressure, or breast cancer. It is also not recommended for women over the age of 35 who smoke, as this combination greatly increases the risk of serious cardiovascular complications. Talk to your doctor to ensure this option is safe for your specific medical history.

Certain medications, including some anti-seizure drugs and specific antibiotics, can make Loette Tablet less effective, increasing the risk of unexpected pregnancy. Avoid smoking while using this treatment, as it raises your risk of heart problems and blood clots. If you are pregnant, planning to become pregnant, or breastfeeding, consult your healthcare provider before starting this treatment.

Uses of Loette Tablet

Loette Tablet is used to treat contraception and dysmenorrhea (irregular menstrual periods). The detailed uses of Loette Tablet are as follows:

Pregnancy Prevention (Contraception): Loette Tablet is highly effective at preventing unwanted pregnancy by stopping the release of an egg from the ovaries, thickening cervical mucus to block sperm, and altering the womb lining.
Irregular Menstrual Cycles: This medication regulates your hormone levels, helping to establish a highly predictable and consistent monthly period cycle.
Painful or Heavy Periods: Loette Tablet lightens blood flow and reduces painful uterine cramping, making your monthly cycles much more manageable.

Key Benefits

Loette Tablet helps provide reliable contraception while supporting better menstrual cycle control and reproductive health. Regulating hormone levels can help improve menstrual symptoms and offer greater predictability in your monthly cycle. Benefits may include:

• Provides effective and reliable pregnancy prevention when used as directed.
• Helps regulate menstrual cycles and improve cycle predictability.
• Reduces menstrual cramps and discomfort during periods.
• Helps decrease heavy menstrual bleeding and associated symptoms.
• May improve acne and other hormone-related skin concerns in some women.
• May help manage symptoms associated with conditions such as endometriosis and provide certain long-term reproductive health benefits.

Directions for Use

Swallow the tablet whole with a full glass of water. Do not chew, crush, or break the tablet.
Take one tablet every day at the exact same time. Setting a daily alarm on your phone can help you stay consistent.
You can take this medication with or without food. If you experience mild nausea, taking it after your evening meal or right before bed may help.
Follow the arrows and days printed on the blister pack to keep track of your daily doses.

How Loette Tablet Works

Loette Tablet contains Ethinylestradiol and Levonorgestrel. • Ethinylestradiol: It helps prevent pregnancy by stopping the release of an egg from the ovaries. It also helps regulate the menstrual cycle and reduce irregular bleeding. • Levonorgestrel: It helps prevent pregnancy by thickening the fluid at the entrance of the womb, making it difficult for sperm to reach an egg. It also helps make the lining of the womb less suitable for implantation.

Alcohol

Unsafe

You are recommended not to consume alcohol along with Loette Tablet to avoid unpleasant side effects.

Pregnancy

Unsafe

Caution should be exercised. Hormonal medicines can affect the developing baby. It is advisable to consult a doctor before using it.

Breast Feeding

Unsafe

Not safe; this Loette Tablet may pass into breast milk. They may harm the baby and also may affect the production of milk. So, this Loette Tablet is unsafe for breastfeeding mothers.

Driving

Caution

Loette Tablet has no or negligible influence on the ability to drive or use machines.

Liver

Caution

Loette Tablet to be taken with caution, especially if you have a history of Liver diseases/conditions. The dose may have to be adjusted by your doctor.

Kidney

Caution

Loette Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

Children

Caution

Loette Tablet is not recommended for children. Safety and efficacy of Loette Tablet are established in women of reproductive age. But sufficient studies have not been performed on women less than 16 years of age. So, take Loette Tablet only when prescribed by a doctor.

Heart

Unsafe

Loette Tablet is not recommended for use in heart patients as it can lead to side effects like heart attack, blood clots, or stroke in some patients.

Geriatrics

Unsafe

Loette Tablet is not recommended for use in elderly patients and postmenopausal women.

What if I have taken an overdose of Loette Tablet

If you accidentally take more than your prescribed dose, seek emergency medical care immediately. While an overdose of this medication is unlikely to be life-threatening, it can cause symptoms such as severe nausea, vomiting, or unexpected vaginal bleeding. Contact a healthcare provider or your local poison control center right away.

Diet & Lifestyle Advise

Do not smoke: Smoking significantly increases your risk of serious cardiovascular complications, including blood clots, heart attacks, and strokes, especially if you are over 35.
Stay active on long journeys: If you are traveling for more than four hours, make sure to stretch your legs, walk around, or perform simple foot exercises to keep blood circulating and prevent blood clots.
Monitor your blood pressure: This medication can sometimes raise blood pressure. Check your blood pressure regularly at home or during routine doctor visits.
Limit alcohol intake: Excessive drinking can place extra strain on your liver, which is responsible for processing this medication.
Maintain a balanced diet: Eating foods rich in calcium and vitamin D can help support bone health, which is important for overall hormonal wellness.

Health Queries

Is it safe to use the Loette tablet for seven years, how much longer can I safely continue taking it, and what should I do to manage my loss of sex drive?

Vikas Singh

M Pharmacy

Loette Tablet can be used safely for several years in many women if regular medical checkups are normal and there are no major risk factors such as smoking, uncontrolled high blood pressure, migraine with aura, blood clot history, liver disease, or certain heart conditions. Many women continue combined birth control pills safely until their late 30s or 40s under medical supervision, but long-term use should be reviewed periodically by a gynaecologist to monitor blood pressure, weight, and overall health. Reduced sex drive can sometimes occur with hormonal contraceptive pills, stress, relationship factors, anxiety, poor sleep, hormonal changes, or other medical conditions. Doctors may consider changing the pill type, adjusting hormone dose, or suggesting another contraceptive method if the symptoms are significant. Regular exercise, stress reduction, proper sleep, open communication with your partner, and management of anxiety or depression may also help improve libido. Please consult a gynaecologist for proper evaluation if the low sex drive is persistent, affecting your relationship, or associated with pain, mood changes, or vaginal dryness.

I am taking Loette Tablet for ovarian cysts. I started the 21-day pack on day 4 of my period, but I missed 2 tablets after 5 days. Now I am having bleeding again. Should I continue the remaining tablets in this cycle, or stop and restart on day 5 of my next period?

Chandrakanta Jena

Pharm D

You should continue taking the remaining tablets in your current pack as scheduled, as stopping midway may further disturb your hormone balance and worsen cycle irregularity. The bleeding you are experiencing is likely breakthrough bleeding due to missed doses. However, your contraceptive protection may be reduced, so you should use an additional barrier method like condoms for the next 7 days. If you had unprotected intercourse after missing the tablets, consider taking a pregnancy test or consulting your doctor for further guidance.

My doctor has advised me to start taking Loette Tablet from the third day of my period to manage the thickness of my uterine lining. I am concerned about whether this medicine may cause any serious side effects. Please tell me what side effects I should watch for.

Dr. S Aneela

M. Pharm (Pharmacology)., PhD

Loette Tablet (Ethinylestradiol and Levonorgestrel) is commonly prescribed to regulate menstrual cycles by balancing hormones and to reduce excessive uterine lining thickness. Most people tolerate it well, but some may experience mild side effects such as headache, nausea, stomach pain, breast pain, weight gain, or light vaginal bleeding. These effects usually improve as your body adjusts to the medicine. However, if you develop severe headaches, unusual swelling, heavy bleeding, chest pain, or breathlessness, please contact your doctor promptly. Always take the medicine exactly as prescribed and inform your doctor if any side effects persist or worsen.

if I am starting Loette tablets for the first time, on which day of my period should I begin taking them?

Bayyarapu Mahesh Kumar

M Pharmacy

Before starting Loette tablets for the first time, consult your doctor to ensure they are suitable for you. Based on your health and medical history, your doctor will advise the most appropriate way to begin. It is generally safest to start on the first day of your period, as this provides immediate contraceptive protection.

I have been taking Loette for the last three months, and this is my third month. I saw spotting when one tablet was left, and I want to start the new pack on the ninth day because I am going out of the station and I do not want my period to come on those days, so what should I do?

Bayyarapu Mahesh Kumar

M Pharmacy

It is essential to discuss this with a doctor who can guide you on the safest way to adjust your pill timing based on your medical history and travel plans, as this depends on various factors, including your overall health.

Have a query?

How Soon It Starts Working

The time required for Loette Tablet to start to work: Loette Tablet ideally shows its action within 7 days of consistent use.

The time for which the effects of Loette Tablet last: The effect of Loette Tablet lasts for 7.7 to 15 hours.

What if you forget to take Loette Tablet

If you miss a dose, take it as soon as you remember, even if that means taking two tablets in one day. Continue taking your subsequent tablets at your regular scheduled time. Depending on when and how many tablets you missed, you may need to use a backup barrier method of contraception (such as condoms) for the next 7 days. Please consult the patient leaflet that came with your pack or talk to your doctor or pharmacist for precise guidance based on your specific cycle week.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

Inspect the medicine before use: Always check the expiration date and ensure the blister pack is intact before taking your tablet.
Take your tablet at the same time every day: Consistent daily dosing helps maintain reliable contraceptive protection. Consider using an alarm or reminder app to avoid missed doses.
Use backup contraception when needed: If you experience severe vomiting or diarrhea within 3 to 4 hours of taking a tablet, treat it as a missed dose and use a backup contraceptive method, such as condoms, for the next 7 days.
Inform healthcare providers before surgery: Tell your surgeon or doctor if you have a planned surgery or expect prolonged immobility. You may need to stop Loette Tablet several weeks before the procedure to help reduce the risk of blood clots.
Remember the limitations of protection: Loette Tablet helps prevent pregnancy but does not protect against HIV or other sexually transmitted infections. Use condoms if protection against sexually transmitted infections is needed.
Follow the correct starting instructions: Contraceptive protection usually begins immediately if the medicine is started on the first day of your menstrual period. If started on any other day, use a reliable backup contraceptive method for the first 7 days.
Seek advice when changing contraceptive methods: Consult your doctor or pharmacist for guidance when switching from another birth control pill, injection, implant, IUD, or patch to help maintain continuous contraceptive protection.
Use with special care after childbirth or abortion: The appropriate time to start Loette Tablet after childbirth, abortion, or during breastfeeding depends on your individual situation. Follow your healthcare provider’s instructions carefully.

Drug-Drug Interactions

Drug-Drug Interactions

Anti-seizure medicines (e.g., carbamazepine, phenytoin, phenobarbital): These medicines can reduce the effectiveness of Loette Tablet and increase the risk of unintended pregnancy.
Tuberculosis medicines (e.g., rifampin): Taking these alongside Loette Tablet can significantly lower hormone levels in the body, making the contraceptive less reliable.
Herbal supplements (e.g., St. John's Wort): These supplements may speed up the breakdown of hormones in Loette Tablet , increasing the risk of breakthrough bleeding and contraceptive failure.

Drug-Food Interactions

Grapefruit and grapefruit juice: Consuming grapefruit products while taking Loette Tablet may increase hormone levels in the bloodstream and raise the risk of side effects.

Drug-Disease Interactions

Blood clotting disorders: Loette Tablet can significantly increase the risk of dangerous blood clots in people with existing clotting disorders.
Severe liver disease: Do not take Loette Tablet if you have active liver disease or liver tumors, as it may worsen liver function.
Uncontrolled high blood pressure: Loette Tablet may further increase blood pressure and raise the risk of serious complications such as stroke or heart attack.
Migraines with aura: Loette Tablet may increase the risk of stroke in people who experience migraines accompanied by visual disturbances or other neurological symptoms

Ethinylestradiol + LevonorgestrelEtretinate

Critical

Ethinylestradiol + LevonorgestrelAcitretin

Critical

Drug-Drug Interactions

Ethinylestradiol + LevonorgestrelEtretinate

Critical

How does the drug interact with Loette Tablet:
Using Etretinate with Ethinylestradiol, Levonorgestrel can increase the risk of side effects during pregnancy.

How to manage the interaction:
Taking Etretinate with Ethinylestradiol, Levonorgestrel can cause an interaction, consult a doctor before taking it. In case you experience any unusual symptoms, consult a doctor. Do not stop using any medications without talking to a doctor.

Ethinylestradiol + LevonorgestrelAcitretin

Critical

How does the drug interact with Loette Tablet:
Co-administration of Acitretin with Ethinylestradiol, Levonorgestrel can increase the risk of side effects during pregnancy.

How to manage the interaction:
Taking Acitretin with Ethinylestradiol, Levonorgestrel together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. Consult a doctor if you get pregnant while taking these medications. Do not stop using any medications without talking to a doctor.

Ethinylestradiol + LevonorgestrelTranexamic acid

Critical

How does the drug interact with Loette Tablet:
Taking Ethinylestradiol, Levonorgestrel with Tranexamic acid may increase the risk of blood clots.

How to manage the interaction:
Taking Ethinylestradiol, Levonorgestrel with Tranexamic acid can lead to an interaction, but can be taken if a doctor has prescribed it. However, if you experience any symptoms like chest tightness, shortness of breath, blood in the urine, blood in the cough, disturbances in eye sight or swelling in the arms or legs, consult a doctor. Do not stop using any medications without talking to a doctor.

Ethinylestradiol + LevonorgestrelBoceprevir

Severe

How does the drug interact with Loette Tablet:
Co-administration of Ethinylestradiol, Levonorgestrel with Boceprevir together may decrease the blood levels of Ethinylestradiol, Levonorgestrel.

How to manage the interaction:
Although there is a possibility of interaction between Ethinylestradiol, Levonorgestrel with Boceprevir, they can be taken if prescribed by a doctor. In case you experience any unusual symptoms like menstrual irregularities, dryness in the vaginal region or feeling of warmth in the upper part of the body, consult a doctor. Do not stop taking any medications without consulting a doctor.

Ethinylestradiol + LevonorgestrelPhenytoin

Severe

How does the drug interact with Loette Tablet:
Co-administration of Ethinylestradiol, Levonorgestrel with Phenytoin together may decrease the blood levels of Ethinylestradiol, Levonorgestrel.

How to manage the interaction:
Although there is a possibility of interaction between Ethinylestradiol, Levonorgestrel with Phenytoin, they can be taken if prescribed by a doctor. In case you experience any unusual symptoms, consult a doctor. Do not stop taking any medications without consulting a doctor.

Ethinylestradiol + LevonorgestrelAnastrozole

Severe

How does the drug interact with Loette Tablet:
Co-administration of Ethinylestradiol, Levonorgestrel with Anastrozole together may decrease the blood levels of anastrozole.

How to manage the interaction:
Although there is a possibility of interaction between Ethinylestradiol, Levonorgestrel with Anastrozole, they can be taken if prescribed by a doctor. In case you experience any unusual side effects, consult a doctor. Do not stop taking any medications without consulting a doctor.

Ethinylestradiol + LevonorgestrelPrimidone

Severe

How does the drug interact with Loette Tablet:
Co-administration of Ethinylestradiol, Levonorgestrel with Primidone together may decrease the blood levels of Ethinylestradiol, Levonorgestrel.

How to manage the interaction:
Although there is a possibility of interaction between Ethinylestradiol, Levonorgestrel with Primidone, they can be taken if prescribed by a doctor. In case you experience any unusual symptoms like menstrual irregularities, dryness in the vaginal region or feeling of warmth in the upper part of the body, consult a doctor. Do not stop taking any medications without consulting a doctor.

Ethinylestradiol + LevonorgestrelRifampicin

Severe

How does the drug interact with Loette Tablet:
Co-administration of Ethinylestradiol, Levonorgestrel with Rifampicin together may decrease the blood levels of Rifampicin.

How to manage the interaction:
Although there is a possibility of interaction between Ethinylestradiol, Levonorgestrel with Rifampicin, they can be taken if prescribed by a doctor. In case you experience any unusual side effects, consult a doctor. Do not stop taking any medications without consulting a doctor.

Ethinylestradiol + LevonorgestrelBexarotene

Severe

How does the drug interact with Loette Tablet:
Co-administration of Ethinylestradiol, Levonorgestrel with Bexarotene together may decrease the blood levels of Ethinylestradiol, Levonorgestrel.

How to manage the interaction:
Although there is a possibility of interaction between Ethinylestradiol, Levonorgestrel with Bexarotene, they can be taken if prescribed by a doctor. In case you experience any unusual symptoms like menstrual irregularities, dryness in the vaginal region or feeling of warmth in the upper part of the body, consult a doctor. Do not stop taking any medications without consulting a doctor.

Ethinylestradiol + LevonorgestrelRifapentine

Severe

How does the drug interact with Loette Tablet:
Co-administration of Ethinylestradiol, Levonorgestrel with Rifapentine together may decrease the blood levels of Ethinylestradiol, Levonorgestrel.

How to manage the interaction:
Although there is a possibility of interaction between Ethinylestradiol, Levonorgestrel with Rifapentine, they can be taken if prescribed by a doctor. In case you experience any unusual symptoms like menstrual irregularities, dryness in the vaginal region or feeling of warmth in the upper part of the body, consult a doctor. Do not stop taking any medications without consulting a doctor.

Drug-Food Interactions

ETHINYLESTRADIOL-0.02MG+LEVONORGESTREL-0.1MGGrapefruit and Grapefruit Juice

Moderate

Drug-Food Interactions

ETHINYLESTRADIOL-0.02MG+LEVONORGESTREL-0.1MGGrapefruit and Grapefruit Juice

Moderate

Common Foods to Avoid:
Grapefruit, Grapefruit Juice

How to manage the interaction:
Taking Grapefruit or Grapefruit juice while on the treatment with Ethinylestradiol, Levonorgestrel can lead to increase in blood levels of Ethinylestradiol, Levonorgestrel. Avoid or limit the consumption of grapefruit and grapefruit juice during treatment with Ethinylestradiol, Levonorgestrel.

All Substitutes & Brand Comparisons

RX
Florina L Tablet 21's
Unicure India Pvt Ltd
₹182.5
(₹8.69 per unit)
56% CHEAPER
RX
OVILOW TABLET 21'S
Svizera Healthcare
₹269.5
(₹12.83 per unit)
35% CHEAPER

Habit Forming

Therapeutic Class

[CONTRACEPTIVES]

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Author Details

Written By

Lakshmithulasi Yarragunta
PharmD (PB)

Reviewed By

Dr Aneela Siddabathuni
MPharma., PhD

Last Updated

Jun 30, 2026 | 6:18 PM IST

We provide you with authentic, trustworthy and relevant information.

See our editorial policy

Reference

Country of origin

INDIA

Manufacturer/Marketer address

The Capital, 1802, 18th Floor , Plot No. C-70, ?G? Block , Bandra Kurla Complex, Bandra East , Mumbai ? 400051.

Other Info - LOE0001

Buy Now

Add to Cart

Welcome User

Loette Tablet 21's

Delivery Information

More about the Product

Composition :

Manufacturer/Marketer :

Consume Type :

Expires on or after :

Return Policy :

About Loette Tablet

Uses of Loette Tablet

Key Benefits

Directions for Use

How Loette Tablet Works

Alcohol

Pregnancy

Breast Feeding

Driving

Liver

Kidney

Children

Heart

Geriatrics

What if I have taken an overdose of Loette Tablet

Diet & Lifestyle Advise

Health Queries

Is it safe to use the Loette tablet for seven years, how much longer can I safely continue taking it, and what should I do to manage my loss of sex drive?

I am taking Loette Tablet for ovarian cysts. I started the 21-day pack on day 4 of my period, but I missed 2 tablets after 5 days. Now I am having bleeding again. Should I continue the remaining tablets in this cycle, or stop and restart on day 5 of my next period?

My doctor has advised me to start taking Loette Tablet from the third day of my period to manage the thickness of my uterine lining. I am concerned about whether this medicine may cause any serious side effects. Please tell me what side effects I should watch for.

if I am starting Loette tablets for the first time, on which day of my period should I begin taking them?

I have been taking Loette for the last three months, and this is my third month. I saw spotting when one tablet was left, and I want to start the new pack on the ninth day because I am going out of the station and I do not want my period to come on those days, so what should I do?

How Soon It Starts Working

What if you forget to take Loette Tablet

Storage

Drug Warnings

Drug-Drug Interactions

Drug-Drug Interactions

Drug-Food Interactions

Drug-Food Interactions

All Substitutes & Brand Comparisons

Florina L Tablet 21's

OVILOW TABLET 21'S

Customers Also Bought

Apollo Life Giloy Tulsi Plus Juice, 500 ml

Apollo Pharmacy Vitamin C Effervescent, 20 Tablets

Habit Forming

Therapeutic Class

FAQs

What is the use of Loette Tablet ?

Can Loette Tablet cause spotting in between the regular periods?

Can Loette Tablet cause weight gain?

Does Loette Tablet also protect from sexually transmitted disease (STDs) and AIDS?

When will I get my menstrual periods after taking the last pill?

In which conditions should I avoid taking Loette Tablet ?

What if I forget to take Loette Tablet ?

Is Loette Tablet safe for women with a history of breast cancer?

Is Loette Tablet a 21-day pill used for regulating periods?

How and in what dose should I take Loette Tablet ?

Is Loette Tablet safe for smokers?

What if I vomit after taking Loette Tablet ?

What are the common side effects of Loette Tablet ?

Can I take Loette Tablet while I am breastfeeding?

How long does Loette Tablet take to start preventing pregnancy?

Can I take Loette Tablet with other everyday pain relievers?

Author Details

Reference

Country of origin

Manufacturer/Marketer address

Buy best Obstetrics And Gynaecology products by

Category

Sub-Category

Brand

Manufacturer

Product-Type