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  3. Lupithral 250mg Tablet

Lupithral 250mg Tablet, Pack of 1 Tablet
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Composition :

AZITHROMYCIN-250MG

Consume Type :

ORAL

Return Policy :

Not Returnable

About Lupithral 250mg Tablet

Lupithral 250mg Tablet is an antibiotic used to treat various bacterial infections such as pneumonia, bronchitis, tonsillitis, pharyngitis and sinusitis, acne, ear infections, and sexually transmitted infections. A bacterial infection is a condition in which bacteria grow in the body and cause infection. 

Lupithral 250mg Tablet contains azithromycin, which slows the growth or sometimes kills the harmful bacteria by preventing the production of proteins required by the bacteria for its survival. Lupithral 250mg Tablet does not treat a viral infection like the flu or a common cold.

Not everyone who is taking Lupithral 250mg Tablet will get these side effects. Some common side effects of Lupithral 250mg Tablet are diarrhoea, nausea, vomiting, and indigestion. These side effects are temporary and may resolve on their own over time. However, if these side effects persist, don't hesitate to contact your doctor.

Lupithral 250mg Tablet should only be taken if advised by your doctor. It can be taken with or without food but should be consumed at a fixed time for the best results. The Lupithral 250mg Tablet should not be consumed in a dose exceeding the recommended amount to avoid unpleasant side effects. Also, the course should be completed even if you feel better.

Inform your physician if you are allergic to Lupithral 250mg Tablet, or have any history of liver problems, muscle problems, arrhythmia, or low potassium or magnesium levels.  Avoid too much exposure to sunlight as Lupithral 250mg Tablet can make your skin sensitive to sunburn. In this case, it is advisable to wear protective clothing or apply sunscreen (SPF 30 or higher) when you are outdoors. Let your doctor know if you are pregnant or breastfeeding before taking Lupithral 250mg Tablet.

Uses of Lupithral 250mg Tablet

Lupithral 250mg Tablet is used in the treatment of bacterial infections. The detailed uses of Lupithral 250mg Tablet are as follows:<br/> 

  • Treatment of Bacterial Infections: Lupithral 250mg Tablet is commonly prescribed for managing bacterial infections, including respiratory tract infections such as pneumonia and bronchitis.<br/> 
  • Skin and Soft Tissue Infections: Lupithral 250mg Tablet effectively treats skin conditions like cellulitis and other soft tissue infections caused by bacteria that respond to this medication.<br/> 
  • Sexually Transmitted Infections (STIs): Lupithral 250mg Tablet is widely used in the treatment of STIs such as Chlamydia and gonorrhea, due to its efficacy against the bacteria responsible for these diseases.<br/> 
  • Ear Infections (Otitis Media): Lupithral 250mg Tablet is also employed in the treatment of otitis media, a middle ear infection often seen in children, to alleviate symptoms and combat the infection.<br/>

Directions for Use

  • Lupithral 250mg Tablet can be taken with or without food or as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Lupithral 250mg Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

  • Lupithral 250mg Tablet slows the growth or sometimes kills the harmful bacteria by preventing the production of proteins required by the bacteria for its survival.
  • It is better tolerated and has more effective tissue penetration than other similar antibiotics like erythromycin.
  • Doctors prescribe Lupithral 250mg Tablet for people who are intolerant to penicillin antibiotics. 

How Lupithral 250mg Tablet Works

Lupithral 250mg Tablet contains azithromycin, which slows the growth or sometimes kills the harmful bacteria by preventing the production of proteins required by the bacteria for its survival.

Storage

Store in a cool and dry place away from sunlight
Side effects of Lupithral 250mg Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
  • Avoid taking raw fruits, nuts and vegetables.
  • Do not share your personal things with others like toothbrushes.
  • Clean the wounds and cuts using soap and water.
  • Wash your hands thoroughly and frequently and maintain hygiene.
  • Get a good quality of sleep.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

What if I have taken an overdose of Lupithral 250mg Tablet

Do not take more than the prescribed dose of Lupithral 250mg Tablet as it may cause overdose. Please consult a doctor immediately if you notice any symptoms like dizziness, chest pian, blurred visin, irregular heartbeat, weakness or difficulty breathing.

Drug Warnings

  • Avoid taking Lupithral 250mg Tablet if you are allergic to it or other macrolide antibiotics.
  • Tell your doctor if you have any history of liver problems, jaundice, myasthenia gravis, heart rhythm disorder (arrhythmia), or electrolyte imbalance (low potassium or magnesium level).
  • In rare cases, the use of Lupithral 250mg Tablet can cause diarrhoea, so if you have watery or bloody diarrhoea, stop taking Lupithral 250mg Tablet and call your doctor. However, do not take any anti-diarrheal medication until your doctor advises you to do so.
  • Consult your doctor if you are pregnant, planning for pregnancy or breastfeeding before using Lupithral 250mg Tablet.
  • Inform the doctor if you are using cholesterol-lowering drugs (like simvastatin, lovastatin, etc.), anti-gout drugs (colchicine) and medicine for treating overactive bladder (tolterodine).
  • Lupithral 250mg Tablet is not recommended for patients with pneumonia (a lung disease) who are judged to be inappropriate for oral therapy due to moderate to severe illness or risk factors.
  • It is always important to check the expiry date of the medicine. Discard the medicine if it reaches the expiry date.

Drug-Drug Interactions

verifiedApollotooltip
AzithromycinZiprasidone
Critical
AzithromycinIloperidone
Severe

Drug-Drug Interactions

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AzithromycinZiprasidone
Critical
How does the drug interact with Lupithral 250mg Tablet:
Co-administration of Lupithral 250mg Tablet with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Ziprasidone and Lupithral 250mg Tablet but can be taken together if prescribed by a doctor. Contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
AzithromycinIloperidone
Severe
How does the drug interact with Lupithral 250mg Tablet:
Taking Lupithral 250mg Tablet with iloperidone increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Though administration of Lupithral 250mg Tablet alongside iloperidone can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, get medical treatment immediately. Do not discontinue any medications without consulting a doctor.
AzithromycinMifepristone
Severe
How does the drug interact with Lupithral 250mg Tablet:
Taking Lupithral 250mg Tablet with mifepristone increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Although Lupithral 250mg Tablet with mifepristone can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, weakness, tiredness, drowsiness, confusion, painful muscle cramping, nausea, or vomiting, constipation, abdominal cramping, chest pain, and/or swelling in the legs or feet, get medical attention. Do not discontinue any medications without consulting a doctor.
AzithromycinVemurafenib
Severe
How does the drug interact with Lupithral 250mg Tablet:
Taking Lupithral 250mg Tablet with vemurafenib increases the risk of an abnormal heart rhythm. If you're dealing with other cardiac illnesses, electrolyte imbalances (for example, magnesium or potassium loss likely due to serious or prolonged diarrhoea or vomiting), you may be at greater risk.

How to manage the interaction:
Although administration of Lupithral 250mg Tablet alongside vemurafenib can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
AzithromycinBisacodyl
Severe
How does the drug interact with Lupithral 250mg Tablet:
Co-administration of Bisacodyl and Lupithral 250mg Tablet together can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Although there is an interaction, Bisacodyl can be taken with Lupithral 250mg Tablet if prescribed by the doctor. Consult the doctor if you develop sudden dizziness, lightheadedness, fainting, breathing difficulty, or heart palpitations, weakness, tiredness, drowsiness, confusion, tingling, numbness, muscle pain, cramps, nausea, or vomiting. Do not discontinue the medications without consulting a doctor.
AzithromycinColchicine
Severe
How does the drug interact with Lupithral 250mg Tablet:
Coadministration of Lupithral 250mg Tablet with colchicine may raise colchicine levels in the blood to undesirable levels.

How to manage the interaction:
Concomitant administration of Lupithral 250mg Tablet alongside colchicine can result in an interaction, but it can be taken if a doctor has advised it. Inform your doctor if you have any of the following symptoms: stomach discomfort, nausea, vomiting, diarrhea, fever, muscular pain, weakness, exhaustion, and/or numbness or tingling in your hands and feet. Do not discontinue any medications without consulting a doctor.
AzithromycinEfavirenz
Severe
How does the drug interact with Lupithral 250mg Tablet:
Taking Lupithral 250mg Tablet with efavirenz increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Though administration of Lupithral 250mg Tablet alongside efavirenz can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, get medical treatment immediately. Do not discontinue any medications without consulting a doctor.
AzithromycinBedaquiline
Severe
How does the drug interact with Lupithral 250mg Tablet:
Taking Lupithral 250mg Tablet with bedaquiline may increase the risk of an abnormal heart rhythm.

How to manage the interaction:
Although using Lupithral 250mg Tablet alongside bedaquiline can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
AzithromycinLeflunomide
Severe
How does the drug interact with Lupithral 250mg Tablet:
Taking Lupithral 250mg Tablet with leflunomide can cause liver problems.

How to manage the interaction:
Although there is an interaction between Lupithral 250mg Tablet and leflunomide, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
AzithromycinPapaverine
Severe
How does the drug interact with Lupithral 250mg Tablet:
Taking Lupithral 250mg Tablet with papaverine increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Although administration of Lupithral 250mg Tablet alongside papaverine can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • It would be best to take probiotics after completing the full course of Lupithral 250mg Tablet to replenish healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria, which helps stimulate their growth. Thus fibre foods may help restore healthy gut bacteria after taking a course of antibiotics. Whole grains like whole-grain bread and brown rice should be included in your diet.
  • Avoid consuming too many calcium-enriched foods and drinks, as it may affect the functioning of Lupithral 250mg Tablet.
  • Avoid intake of alcoholic beverages with Lupithral 250mg Tablet as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the Lupithral 250mg Tablet in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTI- BACTERIALS

Lupithral 250mg Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Consult your doctor

It is unknown whether Lupithral 250mg Tablet interacts with alcohol or not. Therefore, inform your doctor if you are alcoholic before taking Lupithral 250mg Tablet.

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Pregnancy

Consult your doctor

There is insufficient information available about the use of Lupithral 250mg Tablet during pregnancy. Therefore you should not use Lupithral 250mg Tablet during pregnancy unless explicitly advised by your doctor.

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Breast Feeding

Consult your doctor

Lupithral 250mg Tablet is partially passed through the mother’s milk, therefore it should not be used if you are breastfeeding.

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Driving

Caution

There are no data available about the influence of Lupithral 250mg Tablet on the ability to drive or operate machines. However, Lupithral 250mg Tablet may cause dizziness and seizures so make sure you are not affected before driving or operating machinery.

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Liver

Consult your doctor

You should tell your doctor if you have liver problems as your doctor may need to alter the normal dose.

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Kidney

Consult your doctor

You should tell your doctor if you have kidney problems as your doctor may need to alter the normal dose.

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Children

Caution

Lupithral 250mg Tablet is not recommended for children less than 6 months of age as the safety and efficacy are not established. For children above 6 months of age, Lupithral 250mg Tablet can be used if the doctor has prescribed it.

Have a query?

FAQs

Lupithral 250mg Tablet is used to treat bacterial infections such as respiratory tract infections (like pneumonia, bronchitis, tonsillitis, pharyngitis and sinusitis), skin infections (like acne and rosacea), ear infections, and sexually transmitted infections. It works by killing the harmful bacteria.

Do not take antacids that contain aluminium or magnesium hydroxide within 2 hours before or after you take Lupithral 250mg Tablet. These antacids can interact with Lupithral 250mg Tablet and make them less effective when taken at the same time.

Never stop the treatment with Lupithral 250mg Tablet on your own as the infection may come back again (relapse) if the prescribed treatment is not completely taken. Before stopping Lupithral 250mg Tablet once discuss this with your doctor.

If you forget to take Lupithral 250mg Tablet, take your dose as soon as possible. If it is almost time for the next dose, just skip that dose and take the next one when it is due. If in doubt, please contact your doctor. Do not take a double dose to make up for a forgotten dose

Lupithral 250mg Tablet can cause diarrhoea, which may be a sign of a new infection. If you have diarrhoea that is watery or bloody, call your doctor. Do not use anti-diarrhoea medicine unless your doctor tells you to.

You should avoid taking Lupithral 250mg Tablet if you have colitis (intestine inflammation), heart rhythm disorder, liver disease (like jaundice), and muscle problem (like myasthenia gravis). Contact your doctor if you have these conditions before taking Lupithral 250mg Tablet.

No, it is a Schedule H drug that can be taken only if your doctor has prescribed it. Taking it on your own or self-medication can cause unwanted side-effects and lead to antibiotic resistance thereby lowering its efficiency.

Yes in some cases, people using Lupithral 250mg Tablet may get a fungal skin infection known as thrush. It happens because Lupithral 250mg Tablet also kills harmless bacteria that protects against thrush.

Lupithral 250mg Tablet is an effective antibiotic that helps treat bacterial infections. It has a broad spectrum of anti-bacterial activity and is effective against gram-positive and gram-negative bacteria.

Lupithral 250mg Tablet can be taken with or without food.

Lupithral 250mg Tablet should be used with caution in patients with liver problems. In some cases, the use of Lupithral 250mg Tablet can cause diarrhoea, so if you have watery or bloody diarrhoea, stop taking Lupithral 250mg Tablet and call your doctor.

Lupithral 250mg Tablet may interact with anti-emetics, neuroleptics, migraine medicines, statins, anticholinergics and anti-gout medicines. Before starting Lupithral 250mg Tablet, let the doctor know if you are taking any other medicines to prevent interactions.

Store Lupithral 250mg Tablet at room temperature, in a cool and dry place. Keep it out of sight and reach of children.

Side effects of Lupithral 250mg Tablet include diarrhoea, nausea, vomiting, and indigestion. Please consult the doctor if any of the side effects persist or worsen.

Lupithral 250mg Tablet slows the growth or sometimes kills the harmful bacteria by preventing the production of proteins required by the bacteria for its survival.

Country of origin

India

Manufacturer/Marketer address

514 - 515 Ild Tower Sohna Road Sec- 47 , Gurgaon, India
Other Info - LU18537

Disclaimer

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Author Details

Veda MaddalaDoctor badge

Reviewed By

Veda Maddala

M Pharmacy

Last Updated

Jul 19, 2025 | 5:50 PM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.2276.pdf
  2. https://www.drugs.com/disease-interactions/azithromycin.html
  3. https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/050670s036,050710s051,050711s050,050784s037lbl.pdf
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