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  3. LYXUMIA 20 PRE FILLED PEN INJECTION

LYXUMIA 20 PRE FILLED PEN INJECTION , Pack of 1 INJECTION
LYXUMIA 20 PRE FILLED PEN INJECTION , Pack of 1 INJECTION
LYXUMIA 20 PRE FILLED PEN INJECTION , Pack of 1 INJECTION
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

LYXUMIA 20 PRE FILLED PEN INJECTION is used to treat type 2 diabetes mellitus (non-insulin-dependent diabetes). It contains Lixisenatide, which works by increasing insulin release from the pancreas during high blood sugar levels and decreasing the hormones that raise the concentration of blood glucose levels. Some common side effects of LYXUMIA 20 PRE FILLED PEN INJECTION include headache, nausea, vomiting, diarrhoea, dizziness, upset stomach, constipation, and injection site reactions like pain/swelling/itching.

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Composition :

LIXISENATIDE-20MCG

Manufacturer/Marketer :

Saf Fermion Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About LYXUMIA 20 PRE FILLED PEN INJECTION

LYXUMIA 20 PRE FILLED PEN INJECTION belongs to the class of 'anti-diabetic medicines' primarily used to improve blood sugar control in adults with type 2 diabetes mellitus (non-insulin-dependent diabetes). Diabetes mellitus is a metabolic disease that causes high blood sugar levels. It occurs when the insulin (a hormone produced by the beta cells of the pancreas) is resistant in breaking the glucose to produce energy (insulin resistance), or the pancreas (an organ behind the stomach) produces little or no insulin at all.

LYXUMIA 20 PRE FILLED PEN INJECTION contains 'Lixisenatide' that belongs to the class of 'incretin mimetics'. Lixisenatide works by increasing insulin release from the pancreas during high blood sugar levels and decreasing the hormones that raise the concentration of blood glucose levels. 

Your doctor will decide the dose and duration based on your medical condition. Some common side effects of LYXUMIA 20 PRE FILLED PEN INJECTION include headache, nausea, vomiting, diarrhoea, dizziness, upset stomach, constipation, and injection site reactions like pain/swelling/itching. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor. 

Before starting LYXUMIA 20 PRE FILLED PEN INJECTION , let your doctor know if you have a history of heart, kidney or liver diseases. Do not take or stop this medicine if the doctor did not advise you. It is advised to limit your alcohol intake while using LYXUMIA 20 PRE FILLED PEN INJECTION to avoid low blood sugar levels further. Pregnant and breastfeeding women should consult their doctor before starting LYXUMIA 20 PRE FILLED PEN INJECTION . LYXUMIA 20 PRE FILLED PEN INJECTION may cause hypoglycaemia (low blood sugar levels) and dizziness affecting your driving ability; hence drive or operate machinery only when you feel better. LYXUMIA 20 PRE FILLED PEN INJECTION is not recommended for children and adolescents under 18 years of age.

Uses of LYXUMIA 20 PRE FILLED PEN INJECTION

Treatment of Type 2 Diabetes mellitus

Directions for Use

• LYXUMIA 20 PRE FILLED PEN INJECTION should be administered subcutaneously (under the skin) in the abdomen, thigh or upper arm as advised by the doctor.• Your doctor will guide you on how to properly self-administer LYXUMIA 20 PRE FILLED PEN INJECTION to ensure safety. Check the label for directions and use it as advised by the doctor.• To avoid irritation, rotate the injection site with each administration. Always ensure that the needle, syringe, or injector pen is sterile before use to avoid infection.

Medicinal Benefits

LYXUMIA 20 PRE FILLED PEN INJECTION comprises 'Lixisenatide.' It is an incretin mimetic that mimics the action of a natural hormone called Incretin (metabolic hormone, which stimulates a decrease in blood glucose levels). It works by increasing insulin release from the pancreas during high blood sugar levels (after meals) and decreases the amount of sugar the liver makes. LYXUMIA 20 PRE FILLED PEN INJECTION is used as an adjunct to diet and exercise to improve glycaemic control.

How LYXUMIA 20 PRE FILLED PEN INJECTION Works

LYXUMIA 20 PRE FILLED PEN INJECTION contains 'Lixisenatide' that belongs to the class of 'incretin mimetics'. Lixisenatide works by increasing insulin release from the pancreas during high blood sugar levels and decreasing the hormones that raise the concentration of blood glucose levels.

Storage

• Store in a cool and dry place away from sunlight.• Keep out of sight and reach of children.• Cold chain - To be stored in cold places at 2ºC to 8ºC.
Side effects of Lyxumia 20 Pre Filled Pen Injection
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If you experience low blood sugar levels, inform your doctor. They will assess the severity and make recommendations for the next actions.
  • Your doctor will assess your symptoms, blood sugar levels, and overall health before recommending the best course of action, which may include treatment, lifestyle modifications, or prescription adjustments.
  • Follow your doctor's instructions carefully to manage the episode and adjust your treatment plan.
  • Make medication adjustments as recommended by your doctor to prevent future episodes.
  • Implement diet and lifestyle modifications as your doctor advises to manage low blood sugar levels.
  • Monitor your blood sugar levels closely for patterns and changes.
  • Track your progress by recording your blood sugar levels, food intake, and physical activity.
  • Seek further guidance from your doctor if symptoms persist or worsen so that your treatment plan can be revised.
  • Injection site reaction can include numbness or redness.
  • Get a physical examination, follow your doctor's instructions, if it worsens or gets swollen.
  • Apply cold compress for pain relief.
  • Practice good hygiene and keep the injection site away from heat and pressure.

What if I have taken an overdose of LYXUMIA 20 PRE FILLED PEN INJECTION

Since LYXUMIA 20 PRE FILLED PEN INJECTION is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly. Overdose of LYXUMIA 20 PRE FILLED PEN INJECTION may cause diarrhoea, loss of appetite, nausea, vomiting, stomach pain, fullness, discomfort, indigestion, and passing of gas.

Drug Warnings

Brief your medical history to the doctor if you have any heart, kidney or liver diseases, pancreatitis (inflammation of the pancreas), dehydration, digestion problems, gall stones, gastroparesis (delayed gastric emptying), hypoglycaemia (low blood sugar levels), or type 1 diabetes before starting LYXUMIA 20 PRE FILLED PEN INJECTION . Do not share an injection pen, cartridge, or syringe with another person, even if the needle is changed. It is advised to limit your alcohol intake while using LYXUMIA 20 PRE FILLED PEN INJECTION to avoid low blood sugar levels further. Pregnant and breastfeeding women should consult their doctor before starting this medication. LYXUMIA 20 PRE FILLED PEN INJECTION may make you feel dizzy, hence drive and operate machinery only when you feel better. LYXUMIA 20 PRE FILLED PEN INJECTION is not recommended for children and adolescents under 18 years of age.

Drug-Drug Interactions

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LixisenatideGatifloxacin
Critical

Drug-Drug Interactions

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LixisenatideGatifloxacin
Critical
How does the drug interact with Lyxumia 20 Pre Filled Pen Injection:
Coadministration of Lyxumia 20 Pre Filled Pen Injection with Gatifloxacin may sometimes affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.

How to manage the interaction:
Although there is a possible interaction, Lyxumia 20 Pre Filled Pen Injection can be taken with Gatifloxacin if prescribed by the doctor. Consult the prescriber if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a fibre-rich diet and include healthy carbohydrates from fruits, vegetables and whole grains to maintain blood glucose levels.
  • Eat at regular intervals.
  • Monitor your weight and exercise regularly to keep your heart healthy.
  • Your doctor also guides you on noticing and managing the early symptoms of high/low blood sugar levels.
  • Gastrointestinal side effects can be managed with simple modifications in your lifestyle. These include cutting down on sugars and fatty foods and avoiding carbonated drinks and foods that cause gas. 

Habit Forming

No

Therapeutic Class

ANTIDIABETICS
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Alcohol

Caution

It is advised to limit alcohol intake since it may worsen the side effects and increase the risk of developing low blood sugar levels.

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Pregnancy

Caution

If you are pregnant, consult your doctor before taking LYXUMIA 20 PRE FILLED PEN INJECTION . Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

There is no sufficient data on how LYXUMIA 20 PRE FILLED PEN INJECTION affects breastfeeding. If you are a nursing mother, please seek medical advice before using LYXUMIA 20 PRE FILLED PEN INJECTION .

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Driving

Caution

LYXUMIA 20 PRE FILLED PEN INJECTION may cause hypoglycaemia (low blood sugar levels) and dizziness affecting your driving ability; hence drive or operate machinery only when you feel better.

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Liver

Caution

Inform your doctor if you have a pre-existing or a history of liver disease before taking LYXUMIA 20 PRE FILLED PEN INJECTION .

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Kidney

Caution

Inform your doctor if you have a pre-existing or a history of kidney disease before taking LYXUMIA 20 PRE FILLED PEN INJECTION .

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Children

Unsafe

LYXUMIA 20 PRE FILLED PEN INJECTION is not recommended for children and adolescents under 18 years of age.

Have a query?

FAQs

LYXUMIA 20 PRE FILLED PEN INJECTION is used to treat Type 2 Diabetes mellitus.

LYXUMIA 20 PRE FILLED PEN INJECTION contains Lixisenatide, which increases the insulin release from the pancreas when your body has high blood glucose levels. Thus, LYXUMIA 20 PRE FILLED PEN INJECTION helps lower the blood sugar levels in type 2 diabetes mellitus.

LYXUMIA 20 PRE FILLED PEN INJECTION may cause low blood sugar levels (hypoglycaemia), making you hungry, dizzy, irritable, confused, anxious, or shaky. To immediately treat hypoglycaemia, eating or drinking fast-acting sugar sources like fruit juices, hard candy, raisins, or non-diet soda is advised.

Your doctor may advise LYXUMIA 20 PRE FILLED PEN INJECTION with or without other anti-diabetic medications based on your blood sugar levels.

Country of origin

Germany

Manufacturer/Marketer address

Millennium City Information Technology Park, Tower-II, Plot No. 62, Block-DN, Sector V, 8th floor, Salt Lake, Kolkata: 700 091
Other Info - LYX0004

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:21 PM IST

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Reference

  1. https://www.medicines.org.uk/emc/product/2966/pil
  2. https://www.webmd.com/drugs/2/drug-165976/lixisenatide-subcutaneous/details
  3. https://www.drugs.com/mtm/lixisenatide.html

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