apollo
logo
0

Welcome User

Login/Sign Up

Home
Buy Medicines
Lab Tests
Doctor Consult
Circle Membership
insurance
Blogs
Contact Us
Privacy Policy
Return & Refunds
Need Help
Terms and Conditions
Select Delivery Location
compositionComposition:ADALIMUMAB-40MG
prescriptionPrescription Medicine
Mabvinra 40 mg Injection 0.4 ml

Mabvinra 40 mg Injection is used to help reduce signs and symptoms of autoimmune disorders such as Rheumatoid arthritis, Ankylosing spondylitis, Psoriatic arthritis, Plaque psoriasis, Crohn's disease, Uveitis and Ulcerative colitis. It consists of Adalimumab, which works by inhibiting the TNF-α and TNF-β binding to the cell surface, thereby making the TNF cytokine inactive. This helps reduce inflammation and pain caused by various autoimmune diseases.

Read more
Written By Lakshmithulasi Yarragunta ,
Reviewed By Santoshini Reddy G , M Pharmacy
OffersOffers & Discounts

Get Free delivery (₹99) with circle icon

Join Circle
coupon
Get Extra 18% Off with Coupons
coupon
coupon
coupon
Extra 10% Off with Bank Offers

More about the Product

Composition :

ADALIMUMAB-40MG

Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

Mabvinra 40 mg Injection  belongs to the class of monoclonal TNF (Tumor necrosis factor) inhibitors that help reduce signs and symptoms of autoimmune disorders. It is primarily used in the treatment of rheumatoid arthritis, ankylosing spondylitis, juvenile idiopathic arthritis, plaque psoriasis, and psoriatic arthritis. This medicine is also used in the treatment of Crohn’s disease, ulcerative colitis, hidradenitis suppurativa, and uveitis.

Mabvinra 40 mg Injection consists of Adalimumab, which works by inhibiting the TNF-α and TNF-β binding to the cell surface, thereby making the TNF cytokine inactive. This helps reduce inflammation and pain caused by various autoimmune diseases.

Mabvinra 40 mg Injection may cause certain side effects such as nausea, headache, back pain, upper respiratory tract infections, vision problems, dizziness, pale skin, numbness, chest pain, rash, and injection site reactions. Most of these side effects do not require medical attention or resolve over time. However, if these side effects persist for longer, please consult your doctor on priority. Mabvinra 40 mg Injection is a parenteral medicine. It will be administered by a trained healthcare doctor. Hence, do not self-administer. Your physician will decide the dose and duration of the medicine based on the type and severity of the condition.

Mabvinra 40 mg Injection should be avoided if you are allergic to any of its components.  Inform your doctor if you have any history of serious infections, tuberculosis, optimistic infections, cancer, alcoholic hepatitis, hepatitis B virus infection, heart failure, liver, heart, or kidney diseases, or a weak immune system, as it can worsen your health condition. Mabvinra 40 mg Injection may cause dizziness, so drive only if you are alert and focused. Mabvinra 40 mg Injection should not be given to children under two years of age as safety has not been established. Consult the doctor if you are pregnant or breastfeeding.

Uses of Mabvinra 40 mg Injection

Mabvinra 40 mg Injection is used in the treatment of autoimmune inflammatory diseases. The detailed uses of Mabvinra 40 mg Injection are as follows:

  • Treatment of Rheumatoid arthritis (RA): Mabvinra 40 mg Injection reduces inflammation, joint pain, and stiffness in adults with moderate to severe RA, improving mobility and quality of life.
  • Treatment of Juvenile idiopathic arthritis (JIA): Mabvinra 40 mg Injection is used in children to control inflammation, relieve joint symptoms, and support normal growth and development.
  • Treatment of Crohn’s disease: Mabvinra 40 mg Injection treats moderate to severe Crohn’s disease in adults and children by reducing intestinal inflammation when other treatments fail.
  • Treatment of Ulcerative colitis: Mabvinra 40 mg Injection is indicated for adults and children with moderate to severe ulcerative colitis who are unresponsive to conventional therapy.
  • Treatment of Ankylosing spondylitis: Mabvinra 40 mg Injection helps manage chronic back pain and stiffness by reducing spinal inflammation in adults.
  • Treatment of Psoriatic arthritis: Mabvinra 40 mg Injection improves joint and skin symptoms in adults by decreasing swelling, pain, and the formation of psoriatic skin lesions.
  • Treatment of Hidradenitis suppurativa: Mabvinra 40 mg Injection is used in adults and adolescents to reduce painful lumps and inflammation in areas like the armpits and groin.
  • Treatment of Uveitis: Mabvinra 40 mg Injection treats non-infectious uveitis in adults and children by lowering eye inflammation and helping preserve vision.
  • Treatment of Chronic plaque psoriasis: Mabvinra 40 mg Injection is used in adults with moderate to severe plaque psoriasis to reduce red, scaly patches and improve skin appearance.

Key Benefits

Mabvinra 40 mg Injection consists of Adalimumab, which belongs to the class of monoclonal TNF (Tumor necrosis factor) inhibitors. It works by inhibiting the TNF-α and TNF-β binding to the cell surface, thereby making the TNF cytokine inactive. This helps reduce inflammation and pain, redness, and inflammation (swelling) caused by various autoimmune diseases.

Side effects of Mabvinra 40 mg Injection 0.4 ml
Here are the steps to manage the medication-triggered Sinusitis (Sinus infection or Inflammation Of Sinuses):
  • Consult your doctor if you experience symptoms of sinusitis, such as nasal congestion, facial pain, or headaches, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your sinusitis symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • If your doctor advises, you can use nasal decongestants or saline nasal sprays to help relieve nasal congestion and sinus pressure.
  • To help your body recover, get plenty of rest, stay hydrated, and engage in stress-reducing activities. If your symptoms persist or worsen, consult your doctor for further guidance.
  • Drink warm fluids such as warm water with honey, broth, soup or herbal tea to soothe sore throat.
  • Gargle with warm salt water.
  • Suck on lozenges to increase the production of saliva and soothe your throat.
  • Use a humidifier to soothe sore throat as it adds moisture to the air and makes breathing easier.
Here are the steps to manage the medication-triggered Common Cold:
  • Inform your doctor about the common cold symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Drink plenty of fluids, such as warm water or soup, to help thin out mucus.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
  • Talk to your doctor about medicines to manage neutropenia based on the underlying cause.
  • Avoid contact with people who are sick.
  • Wash your hands regularly with soap and water.
  • Avoid unpasteurized dairy products.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Get plenty of rest and avoid activities that tire you out to allow your body fight the infection.
  • Drink lots of fluids to help loosen mucus in the lungs.
  • Use over-the-counter medications like paracetamol or ibuprofen to manage fever.
  • Use a humidifier as it helps soothe irritated airways.
  • Do not make changes to your medication schedule or take over-the-counter medicines without consulting your doctor.
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safety.
  • Mabvinra 40 mg Injection will be administered by the doctor or healthcare professional.
  • Do not self-administer.
Mabvinra 40 mg Injection consists of Adalimumab, which works by inhibiting the TNF-α and TNF-β binding to the cell surface, thereby making the TNF cytokine inactive. This helps reduce inflammation and pain caused by various autoimmune diseases.
bannner image

Alcohol

Consult your doctor

It is not known if alcohol interacts with Mabvinra 40 mg Injection . Please consult the doctor.

bannner image

Pregnancy

Caution

If you are pregnant or planning pregnancy, inform your doctor before receiving Mabvinra 40 mg Injection . Your doctor may prescribe this medicine if the benefits outweigh the risks.

bannner image

Breast Feeding

Caution

If you are breastfeeding, inform your doctor before receiving Mabvinra 40 mg Injection .

bannner image

Driving

Caution

Mabvinra 40 mg Injection will be administered in the hospital setting. Hence, driving is not recommended.

bannner image

Liver

Caution

Mabvinra 40 mg Injection should be used with caution if you have liver disease. Dose adjustment may be needed in patients with liver impairment.

bannner image

Kidney

Caution

Mabvinra 40 mg Injection should be used with caution if you have kidney disease. Dose adjustment may be needed in patients with liver impairment.

bannner image

Children

Caution

Mabvinra 40 mg Injection is not recommended in children below two years of age as safety and efficacy are not established. In children above two years of age, it will be administered by the pediatrician. Mabvinra 40 mg Injection is used in children only for the treatment of juvenile idiopathic arthritis, paediatric Crohn’s disease, and uveitis.

bannner image

Heart

Caution

Mabvinra 40 mg Injection may not be safe for heart patients. Therefore, please inform your doctor if you have any pre-existing heart conditions.

bannner image

Geriatrics

Consult your doctor

Limited information available about the use of Mabvinra 40 mg Injection in geriatric patients. Please consult your physician.

Since Mabvinra 40 mg Injection is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly.

Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching that is less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
  • Massages can also be helpful.
  • Avoid freezing and hot temperatures.
  • Avoid wearing tight-fitting clothes; instead, wear loose garments.
  • Rest well and get plenty of sleep.
  • Stay hydrated; drink plenty of water.

Have a query?

Drug Warnings

Mabvinra 40 mg Injection should be avoided if allergic to it or any other components present. Inform your doctor if you have any history of serious infections, tuberculosis, optimistic infections, cancer, alcoholic hepatitis, hepatitis B virus infection, heart failure, liver, heart or kidney diseases, weak immune system, multiple sclerosis (nerve and muscle disease), or diabetes as it can worsen your health condition. Do not take live vaccines while being treated with Mabvinra 40 mg Injection to prevent any serious consequences. Mabvinra 40 mg Injection is not recommended for use in children below two years of age as safety and efficacy are not established. This medicine is not recommended for patients suffering from sepsis as it can worsen the condition.

Drug-Drug Interactions

verifiedApollotooltip
AdalimumabInfliximab
Severe
AdalimumabMitoxantrone
Severe

Drug-Drug Interactions

Login/Sign Up

AdalimumabInfliximab
Severe
How does the drug interact with Mabvinra 40 mg Injection 0.4 ml:
Taking Infliximab with Mabvinra 40 mg Injection 0.4 ml can increase the risk or severity of developing an infection.

How to manage the interaction:
Taking Infliximab with Mabvinra 40 mg Injection 0.4 ml together can result in an interaction, but it can be taken if your doctor has advised it. If you have any symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you pee, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice.
AdalimumabMitoxantrone
Severe
How does the drug interact with Mabvinra 40 mg Injection 0.4 ml:
Using Mabvinra 40 mg Injection 0.4 ml together with mitoxantrone may increase the risk of serious infections.

How to manage the interaction:
There may be a possibility of interaction between Mitoxantrone and Mabvinra 40 mg Injection 0.4 ml, but it can be taken if prescribed by a doctor. However, if you experience symptoms like stomach pain, ongoing fever, excessive sweating at night, unexplained weight loss, infection, fever, chills, diarrhoea, a sore throat, muscle pain, difficulty breathing, or pain or discomfort when urinating. Do not discontinue any medications without first consulting a doctor.
AdalimumabMercaptopurine
Severe
How does the drug interact with Mabvinra 40 mg Injection 0.4 ml:
When Mabvinra 40 mg Injection 0.4 ml is taken with Mercaptopurine, the effect of Mercaptopurine in the blood may decrease which may increase risk of infection.

How to manage the interaction:
Taking Mercaptopurine with Mabvinra 40 mg Injection 0.4 ml together can possibly result in an interaction, but it can be taken if a doctor has advised it. However contact a doctor immediately, if you experience any symptoms such as infections, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, or pain or burning during urination. Do not discontinue any medications without consulting a doctor.
AdalimumabBaricitinib
Severe
How does the drug interact with Mabvinra 40 mg Injection 0.4 ml:
Coadministration of baricitinib and Mabvinra 40 mg Injection 0.4 ml can raise your risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Mabvinra 40 mg Injection 0.4 ml if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.
AdalimumabGemcitabine
Severe
How does the drug interact with Mabvinra 40 mg Injection 0.4 ml:
Combining Mabvinra 40 mg Injection 0.4 ml with Gemcitabine can increase the risk of side effects like developing serious infections.

How to manage the interaction:
Although taking Gemcitabine and Mabvinra 40 mg Injection 0.4 ml together can cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms like feeling sick, having a fever, diarrhea, a sore throat, muscle aches, weight loss, pain when you pee, or having trouble breathing it's important to call a doctor right away. Do not stop using any medications without talking to a doctor.
AdalimumabAbemaciclib
Severe
How does the drug interact with Mabvinra 40 mg Injection 0.4 ml:
Using Mabvinra 40 mg Injection 0.4 ml together with abemaciclib may increase the risk of serious infections.

How to manage the interaction:
Taking Abemaciclib with Mabvinra 40 mg Injection 0.4 ml together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms of fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AdalimumabCyclophosphamide
Severe
How does the drug interact with Mabvinra 40 mg Injection 0.4 ml:
When Mabvinra 40 mg Injection 0.4 ml is taken with Cyclophosphamide, may increase the risk of serious infections.

How to manage the interaction:
Although taking Cyclophosphamide and Mabvinra 40 mg Injection 0.4 ml together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
AdalimumabNilotinib
Severe
How does the drug interact with Mabvinra 40 mg Injection 0.4 ml:
Using Mabvinra 40 mg Injection 0.4 ml and nilotinib together can increase the risk of developing infections.

How to manage the interaction:
Combining Mabvinra 40 mg Injection 0.4 ml and nilotinib can lead to an interaction, but it can be taken when advised by your doctor. However, if you experience any symptoms like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, body sores, and pain or burning during urination, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
AdalimumabHydrocortisone
Severe
How does the drug interact with Mabvinra 40 mg Injection 0.4 ml:
Co-administration of Mabvinra 40 mg Injection 0.4 ml and hydrocortisone together can increase the risk of developing serious infections.

How to manage the interaction:
Co-administration of Mabvinra 40 mg Injection 0.4 ml and hydrocortisone can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
AdalimumabIdarubicin
Severe
How does the drug interact with Mabvinra 40 mg Injection 0.4 ml:
Combining Idarubicin and Mabvinra 40 mg Injection 0.4 ml can increase the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, Idarubicin can be taken with Mabvinra 40 mg Injection 0.4 ml if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

All Substitutes & Brand Comparisons

No
[IMMUNOSUPPRESSANTS]

FAQs

Mabvinra 40 mg Injection is used to treat Rheumatoid arthritis, Ankylosing spondylitis, Psoriatic arthritis, Plaque psoriasis, Crohn’s disease, Uveitis and Ulcerative colitis.

Mabvinra 40 mg Injection contains Adalimumab, which works by inhibiting the TNF-α and TNF-β binding to the cell surface, thereby making the TNF cytokine inactive.

Mabvinra 40 mg Injection affects your immune system and makes you more susceptible to infections. Hence, it is not recommended in people with active infections like tuberculosis or abnormal liver enzymes. Mabvinra 40 mg Injection can also increase the risk of developing cancers; hence, informing your doctor if you have a history of any cancer is essential.

Mabvinra 40 mg Injection is an antirheumatic medicine that belongs to the TNF (tumor necrosis factor) inhibitor class. It contains the active ingredient Adalimumab.

Treatment with Mabvinra 40 mg Injection can help reduce inflammation, pain, redness, and swelling associated with various autoimmune disorders.

Mabvinra 40 mg Injection which contains Adalimumab, can weaken your immune system. Since it affects the immune system, it may increase your risk of developing infections. It is important to follow your doctor's advice and inform them if you have any existing infections or health concerns before starting treatment.

Mabvinra 40 mg Injection can be used alongside other arthritis medicines such as methotrexate, prednisolone, naproxen, ibuprofen, and paracetamol. However, Mabvinra 40 mg Injection should not be used with other biological disease-modifying antirheumatic drugs (bDMARDs).

Mabvinra 40 mg Injection should be stopped before surgery. It can be resumed after the operation, once the wound has healed and there is no infection, as determined by your surgeon and rheumatologist.

Mabvinra 40 mg Injection causes side effects such as rash, headache, sinusitis, upper respiratory infections, fever, and application site reactions. Therefore, please contact a doctor if these do not reduce and persist for longer durations.

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Author Details

Santoshini Reddy GDoctor badge

Reviewed By

  • Santoshini Reddy G

    M Pharmacy

Last Updated

Doctor imageWe provide you with authentic, trustworthy and relevant information

India
Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - MAB0028

Buy best Immuno Modulators products by

whatsapp Floating Button
Buy Now
Add to Cart