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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Macpod-O Tablet

Macpod-O Tablet is a combination prescription antibiotic used to treat a wide variety of bacterial infections. It is commonly used to clear up respiratory infections, urinary tract issues, and certain types of infectious fevers. By targeting the bacteria causing the illness, this medicine helps your body overcome the infection quickly and completely.

For this medicine to work effectively, you must take it consistently at the exact times your doctor prescribes. It is generally best to take this tablet with food, as this helps your body absorb the medicine properly and prevents stomach upset. During your recovery, drinking plenty of water and getting extra rest will support your immune system as the medicine clears the infection.

While taking Macpod-O Tablet , some people may experience mild side effects like a temporary upset stomach or loose stools. However, if you develop severe watery diarrhoea, intense stomach cramps, or a sudden skin rash, you should stop taking the medicine and consult your doctor immediately. These symptoms can be signs of a more serious reaction that needs prompt medical attention.

Do not take Macpod-O Tablet if you have a history of severe allergic reactions to similar antibiotics. It is also important to talk to your doctor before starting this medicine if you have a history of tendon problems, nerve disorders, or kidney issues, as it contains ofloxacin, which may rarely cause serious tendon injury, nerve damage, or nervous system side effects. Your doctor will determine if this is the safest treatment option for your specific medical background.

Certain medications, such as antacids, can stop your body from absorbing this antibiotic, so you should space them out. It is also highly recommended to avoid alcohol and smoking while taking this medicine, as they can worsen dizziness and strain your immune system. If you are pregnant, breastfeeding, or managing health conditions as an older adult, talk to your doctor to ensure this medicine is safe for you.

Uses of Macpod-O Tablet

Macpod-O Tablet is used to treat a wide range of bacterial infections. The detailed uses of Macpod-O Tablet are as follows:

  • Respiratory Tract Infections: It treats infections in the lungs, throat, sinuses, or airways by stopping the bacteria from multiplying.
  • Urinary Tract Infections (UTIs): It eliminates harmful bacteria in the bladder and kidneys, resolving painful or frequent urination.
  • Skin and Soft Tissue Infections: It targets bacteria causing painful skin swelling, redness, and localised infections.
  • Otitis media: It may also be used to treat bacterial ear infections.
  • Sexually transmitted infections (STIs): It helps treat gonorrhoea and other bacterial STIs.
  • Typhoid Fever: It helps clear severe systemic bacterial infections that cause prolonged high fevers and digestive issues.

Key Benefits

Macpod-O Tablet helps treat bacterial infections and supports a faster return to everyday health and comfort. By helping eliminate infection-causing bacteria, it can reduce symptoms such as fever, pain, and discomfort.

Benefits may include:

  • Helps eliminate bacteria responsible for a wide range of infections.
  • Provides broad protection against susceptible bacteria through a combination of two antibiotics.
  • Helps relieve fever, pain, swelling, and discomfort associated with bacterial infections.
  • Helps reduce the risk of the infection spreading to nearby tissues or deeper parts of the body.
  • Supports complete clearance of infection when the full treatment course is completed.
Side effects of Macpod-O Tablet
  • Rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
  • Wear cotton underwear and loose pants to facilitate better airflow.
  • Try meditation and yoga to reduce stress and improve balance hormones.
  • Eat foods like yogurt or kefir to support vaginal health.
  • Gently clean the genital area with soap and lukewarm water.
  • Avoid fragrant soap, bubble baths, and douches; these can also irritate.
  • Tell your doctor about any medications or supplements you’re taking, as they may affect vaginal discharge treatments.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Directions for Use

  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this can affect how the medicine is absorbed.
  • Take the medicine with food to help your body absorb it better and to protect your stomach from irritation.
  • Space your doses evenly throughout the day to keep a constant level of the medicine in your bloodstream.
  • Always complete the entire course of treatment prescribed by your doctor, even if you feel completely better after a few days. Stopping early can allow the remaining bacteria to multiply and return stronger.

How Macpod-O Tablet Works

Macpod-O Tablet contains Cefpodoxime and Ofloxacin, which work together to destroy harmful bacteria. • Cefpodoxime: It works by preventing the bacteria from building their protective outer cell wall. Without this wall, the bacterial cells cannot hold themselves together; they rupture and die. This action stops the active infection from maintaining its hold in your body. • Ofloxacin: It works by blocking a vital enzyme that bacteria need to repair and copy their genetic material (DNA). Without the ability to copy their DNA, the bacteria cannot reproduce or spread. • Together, these two mechanisms quickly clear the infection from your system.
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Alcohol

Unsafe

Avoid consuming alcohol while taking Macpod-O Tablet as it may cause increased dizziness.

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Pregnancy

Caution

Please consult your doctor if you are pregnant, your doctor will prescribe Macpod-O Tablet only if the benefits outweigh the risks.

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Breast Feeding

Caution

It is unknown if Macpod-O Tablet passes into breastmilk. Consult your doctor before taking Macpod-O Tablet if you are breastfeeding.

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Driving

Caution

Macpod-O Tablet may cause dizziness and vision problems. So, drive only if you are alert.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor before taking Macpod-O Tablet if you have liver impairment/liver disease.

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Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or kidney impairment/kidney disease before taking Macpod-O Tablet .

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Children

Unsafe

Macpod-O Tablet should not be given to children below 18 years.

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Heart

Caution

Macpod-O Tablet should be taken with extreme caution in patients with heart disease. Please consult your physician.

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Geriatrics

Caution

Macpod-O Tablet can be used in geriatric patients, but with caution due to increased sensitivity to side effects like muscle pain, liver enzyme changes, or drug interactions. Medical supervision is essential to ensure safe and effective cholesterol management in older adults.

What if I have taken an overdose of Macpod-O Tablet

If you suspect an overdose or if someone has accidentally swallowed multiple tablets, seek immediate medical attention or contact a local poison control centre. Symptoms of an overdose may include severe dizziness, nausea, or confusion.

Diet & Lifestyle Advise

  • Avoid dairy near your dose: Do not consume milk, cheese, yoghurt, or calcium-fortified juices within 2 hours before or 2 hours after taking your medicine. Calcium can bind to the ofloxacin component and reduce how much of the antibiotic your body absorbs.
  • Stay well hydrated: Drink plenty of water throughout the day to help your kidneys flush out the medication safely and to recover from fluid loss if you have a fever or mild diarrhoea.
  • Protect your skin from the sun: This medicine can make your skin highly sensitive to sunlight. Wear protective clothing, sunglasses, and a broad-spectrum sunscreen when spending time outdoors.
  • Support your gut: Consider eating probiotic-rich foods like kefir or taking a probiotic supplement to support your gut health. Make sure to space probiotics at least 2 hours apart from your antibiotic dose so the medicine doesn't destroy the beneficial bacteria.

Have a query?

How Soon It Starts Working

  • The time required for Macpod-O Tablet to start to work: The time required for Macpod-O Tablet to show its action is unknown.
  • The time for which the effects of Macpod-O Tablet last: The duration of action for Macpod-O Tablet is unknown.

What if you forget to take Macpod-O Tablet

If you miss a dose, take it as soon as you remember. However, if your next scheduled dose is only a few hours away, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a forgotten one.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Finish the course: Never stop taking Macpod-O Tablet early just because your symptoms disappear. Stopping too soon can cause the infection to return and make the bacteria resistant to future treatments.
  • Space your antacids: Do not take antacids, multivitamins, or supplements containing iron, zinc, or magnesium within 2 hours before or after taking this medicine, as they will block its absorption.
  • Avoid alcohol: Refrain from drinking alcohol during your treatment to minimise the risk of severe headaches, dizziness, and stomach discomfort.
  • Report nerve changes: Alert your doctor immediately if you notice any unusual burning, tingling, or loss of sensation in your hands or feet.
  • Important Safety Warning: The ofloxacin component of Macpod-O Tablet may rarely cause serious tendon injury, nerve damage, or central nervous system effects. Stop taking the medicine and seek immediate medical attention if you develop tendon pain, numbness, tingling, weakness, confusion, hallucinations, or seizures.

Drug-Drug Interactions

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Drug-Drug Interactions:

  • Antacids and Minerals (e.g., calcium carbonate, magnesium hydroxide, iron, zinc): Taking these medicines alongside this antibiotic may reduce its absorption and make it less effective.
  • Blood Thinners (e.g., warfarin): This combination may increase the blood-thinning effects, raising the risk of bleeding. Your doctor may need to monitor your blood clotting times.
  • Pain Relievers (e.g., ibuprofen, naproxen): Taking certain pain medicines like ibuprofen alongside this antibiotic may increase the risk of central nervous system irritation or seizures.

Drug-Food Interactions: 

  • Calcium-Rich Foods: Dairy products and calcium-fortified drinks can bind with the medicine in your digestive tract, reducing how much of the dose gets into your system.

Drug-Disease Interactions:

  • Tendon Disorders: This medicine can increase the risk of tendon inflammation and rupture, especially in patients with a history of tendon problems.
  • Kidney Disease: If your kidneys do not filter waste efficiently, the medicine can build up in your body, requiring your doctor to lower your dose.
  • Myasthenia Gravis: This medicine can worsen muscle weakness in people diagnosed with this muscle disorder.

Drug-Drug Interactions

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How does the drug interact with Macpod-O Tablet:
Coadministration of Ofloxacin with Ziprasidone can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Ofloxacin with Ziprasidone together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Macpod-O Tablet:
The combination of Amiodarone and Ofloxacin may significantly increase the risk of an abnormal heart rhythm.

How to manage the interaction:
Taking Amiodarone and Ofloxacin is not recommended as it can lead to an interaction.It can be taken if prescribed by a doctor. If you get dizziness, lightheadedness, fainting, or fast or racing heartbeats, consult a doctor. Do not stop taking any medications without consulting a doctor.
Critical
How does the drug interact with Macpod-O Tablet:
Coadministration of Ofloxacin with Saquinavir can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Ofloxacin with Saquinavir together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Macpod-O Tablet:
Coadministration of Ofloxacin with Sotalol can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Ofloxacin with Sotalol together is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. If you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, contact a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Macpod-O Tablet:
Coadministration of Ofloxacin with Thioridazine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Ofloxacin with Thioridazine together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Critical
How does the drug interact with Macpod-O Tablet:
Using halofantrine together with ofloxacin can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Ofloxacin with Halofantrine together is not recommended as it can cause an interaction, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
How does the drug interact with Macpod-O Tablet:
Coadministration of Ofloxacin with Disopyramide can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Ofloxacin with Disopyramide together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Macpod-O Tablet:
Coadministration of Ofloxacin with Pimozide can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Ofloxacin with Pimozide together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Critical
How does the drug interact with Macpod-O Tablet:
Using Mesoridazine together with Ofloxacin can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Mesoridazine with Ofloxacin is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
How does the drug interact with Macpod-O Tablet:
Coadministration of Ofloxacin with Cisapride can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Ofloxacin with Cisapride together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTI- BACTERIALS]

FAQs

Macpod-O Tablet is used to treat bacterial infections of the lungs (pneumonia), sinus (sinusitis), bladder (cystitis), ear infections, etc.

Macpod-O Tablet is a combination of two antibiotic drugs: Ofloxacin and Cefpodoxime. Ofloxacin inhibits DNA gyrase, which is required to produce DNA replication, transcription, and repair. Cefpodoxime inhibits protein synthesis and leads to cell death, thereby killing the bacteria. Together, Macpod-O Tablet helps in treating bacterial infections.

Avoid taking magnesium and aluminium-containing antacids along with Macpod-O Tablet . Maintain a minimum gap of two hours between both.

Do not take Macpod-O Tablet on your own, as self-medication may lead to antibiotic resistance, which means antibiotics fail to act against specific bacterial infections.

Diarrhoea is the most reported common side effect of Macpod-O Tablet . So, it is advisable to drink lots of water and fluids and eat fibre-rich food if you experience diarrhoea. If you observe blood in stools (tarry stools) or experience excess diarrhoea (vomiting or watery stool), immediately consult your doctor. Do not take anti-diarrheal medicine on your own.

Macpod-O Tablet may cause stomach upset as a side effect. To avoid this, take Macpod-O Tablet , preferably with food. Taking Macpod-O Tablet with food helps in increasing its absorption in the body.

Macpod-O Tablet is a broad-spectrum antibiotic used to treat bacterial infections, and it is not used for viral infections.

No, there is no evidence that Macpod-O Tablet is addictive.

Macpod-O Tablet should be taken for as long as it has been prescribed by the doctor. The duration of treatment will be determined by the doctor based on your medical condition.

Macpod-O Tablet should be taken orally. Swallow it as a whole with water; do not chew, break or crush.

Macpod-O Tablet should be stored in a cool and dry place away from sunlight. Keep it out of sight and reach of children.

You should not stop taking Macpod-O Tablet even though you feel better as it may cause the infection to recur. Complete the duration of treatment as prescribed by the doctor to get its full benefits.

Take the missed dose of Macpod-O Tablet as soon as you remember. But, if it is time for your next dose take your regular dose and skip the missed dose. Do not take a double dose to make up for the missed dose.

Consult the doctor if you don't feel better even after completing the duration of treatment with Macpod-O Tablet . Also, let your doctor know if any symptoms are worsening while taking Macpod-O Tablet .

The side effects of Macpod-O Tablet include dizziness, pain in the lower legs, loss of appetite, neck pain, headache, and stomach pain. Consult the doctor if any of these side effects persist or worsen.

You should avoid consuming large amounts of dairy products like milk or yoghurt close to your dose. Try to avoid dairy products for at least 2 hours before and 2 hours after taking your medicine, as calcium can reduce absorption of the ofloxacin component and make the treatment less effective. Talk to your doctor if you need help planning your meals.

This medicine can cause some people to feel dizzy, sleepy, or less alert. If you experience these side effects, do not drive, ride a bicycle, or operate heavy machinery until you feel fully alert. Talk to your doctor if these symptoms persist.

If you stop taking the medicine early, some of the strongest bacteria may survive. This can cause your infection to return and make the bacteria resistant to antibiotics in the future. Always finish the full course prescribed.

This medicine is generally not recommended during pregnancy or breastfeeding unless your doctor decides it is absolutely necessary. If you are pregnant, planning to become pregnant, or breastfeeding, talk to your doctor before starting this medication.

Yes. In rare cases, certain ingredients in this medicine can cause tendon swelling or rupture, particularly in the Achilles tendon. If you experience sudden joint pain, swelling, or stiffness, stop taking the medicine and talk to your doctor immediately.

The medicine begins fighting susceptible bacteria shortly after your first dose. However, the time needed for noticeable symptom improvement varies depending on the type and severity of the infection. Some people feel better within a few days, while others may take longer. If your symptoms worsen or do not improve after 48 to 72 hours, contact your doctor for further evaluation.

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Country of origin

India

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.
Other Info - MAC0163
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