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  3. Malirid 45 mg Tablet 1's

Malirid 45 mg Tablet 1's, Pack of 1 Tablet
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Composition :

PRIMAQUINE-45MG

Manufacturer/Marketer :

Ipca Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Malirid-45 Tablet

Malirid-45 Tablet belongs to the class 'anti-malarials' primarily used for the treatment of malaria. A disease caused by a plasmodium parasite, transmitted by the bite of infected mosquitoes. The severity of malaria varies based on the species of plasmodium. Symptoms are chills, fever and sweating, usually occurring a few weeks after being bitten. People travelling to areas where malaria is common typically take protective drugs before, during and after their trip. 

Malirid-45 Tablet contains 'primaquine'. It works by increasing the levels of haeme in the blood, a substance toxic to the malarial parasite. This kills the parasite and stops the infection from spreading. In this way Malirid-45 Tablet used for the prevention of relapse of malaria caused by plasmodium vivax and Plasmodium ovale strains of the parasite.

Malirid-45 Tablet should be taken as prescribed by your doctor, preferably with a meal to avoid stomach upset and at fixed intervals every day for best results. The dose of Malirid-45 Tablet can vary depending upon your condition and the severity of the infection. It is recommended to complete medicine and take this medicine as prescribed by your doctor before visiting a malaria-prone area. The common side effects of Malirid-45 Tablet include rash, vomiting, headache, dizziness, hives, stomach pain, nausea, abdominal pain, itching, heartburn, gastrointestinal discomfort, upper abdominal pain. Everyone need not experience the above side effects. In case of any discomfort, stop the medicine and speak with your doctor.

Before starting Malirid-45 Tablet, please inform your doctor if you are allergic to Malirid-45 Tablet. Do not take Malirid-45 Tablet on your own. Malirid-45 Tablet is used in caution with Pregnant/breast-feeding mother. Malirid-45 Tablet is not recommended in patients with heart disease, liver, kidney problems and rheumatoid-arthritis.

Directions for Use

• Take Malirid-45 Tablet with food to decrease the risk of stomach upset.• Follow your doctor’s recommendations on the dosage and timing of this medication to achieve optimal results.• Swallow it as a whole with a glass of water.• Do not crush, chew, or break it.

Medicinal Benefits

Malirid-45 Tablet belongs to the class 'anti-malarials' primarily used for the treatment of malaria. Malirid-45 Tablet contains 'primaquine'. It works by increasing the levels of haeme in the blood, a substance toxic to the malarial parasite. This kills the parasite and stops the infection from spreading. In this way Malirid-45 Tablet used for the prevention of relapse of malaria caused by plasmodium vivax and Plasmodium ovale strains of the parasite. Malirid-45 Tablet can also be given in combination with clindamycin for the treatment of Pneumocystis carinii pneumonia (PCP).

How Malirid-45 Tablet Works

Malirid-45 Tablet contains 'primaquine'. It works by increasing the levels of haeme in the blood, a substance toxic to the malarial parasite. This kills the parasite and stops the infection from spreading.

Storage

Store in a cool and dry place away from sunlight
Side effects of Malirid 45 mg Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

What if I have taken an overdose of Malirid-45 Tablet

Do not take more than the prescribed dose of Malirid-45 Tablet as it may cause overdose. The symptoms of overdose include vomiting, abdominal cramps, fast or irregular heartbeat, fits and extreme drowsiness. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Before starting Malirid-45 Tablet, please inform your doctor if you are allergic to Malirid-45 Tablet. Do not take Malirid-45 Tablet on your own. Malirid-45 Tablet is used in caution with Pregnant/breast-feeding mother. Malirid-45 Tablet is not recommended in patients of heart disease, liver, kidney problems and rheumatoid arthritis. Malirid-45 Tablet is not recommended in patients of diabetes. Malirid-45 Tablet is not recommended for use in acutely ill patients suffering from a systemic disease like rheumatoid arthritis and lupus erythematosus. There is a marked decrease in the number of granulocytes in such conditions. Malirid-45 Tablet is also not recommended for use if you are receiving a medication that can cause anaemia or suppression of the immune system by affecting bone marrow cells as a side effect. Medicine is not recommended for use if you are consuming Quinacrine or any other combination medicine containing quinacrine (anti-malarial drug). Patients should avoid pregnancy during treatment. It is recommended to take this medicine for the entire prescribed duration even when symptoms improve or resolve. Failure to do so might result in drug resistance. Sexually active women can take effective Contraceptive pills and men should use a condom during and 3months after stopping the treatment. Malirid-45 Tablet should be discontinued immediately when leukopenia (reduced white blood cells) occurs.

Drug-Drug Interactions

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PrimaquinePimozide
Critical
PrimaquineAuranofin
Critical

Drug-Drug Interactions

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PrimaquinePimozide
Critical
How does the drug interact with Malirid 45 mg Tablet:
When Pimozide and Malirid 45 mg Tablet are taken together, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Malirid 45 mg Tablet with Pimozide is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
PrimaquineAuranofin
Critical
How does the drug interact with Malirid 45 mg Tablet:
Taking Malirid 45 mg Tablet with Auranofin may cause blood disorders and other severe side effects.

How to manage the interaction:
Taking Malirid 45 mg Tablet with Auranofin is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. Do not discontinue any medications without a doctor's advice.
PrimaquineHalofantrine
Critical
How does the drug interact with Malirid 45 mg Tablet:
Taking Malirid 45 mg Tablet with Halofantrine can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Although taking Malirid 45 mg Tablet with Halofantrine is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
PrimaquineMesoridazine
Critical
How does the drug interact with Malirid 45 mg Tablet:
Using Malirid 45 mg Tablet with Mesoridazine can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Malirid 45 mg Tablet with Mesoridazine is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
PrimaquineCisapride
Critical
How does the drug interact with Malirid 45 mg Tablet:
Coadministration of Malirid 45 mg Tablet with Cisapride can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Malirid 45 mg Tablet with Cisapride is not advised generally as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
PrimaquineAurothioglucose
Critical
How does the drug interact with Malirid 45 mg Tablet:
Taking Malirid 45 mg Tablet with Aurothioglucose may cause blood disorders and other severe side effects.

How to manage the interaction:
Taking Malirid 45 mg Tablet with Aurothioglucose is not advised generally as it can cause an interaction, it can be taken if prescribed by the doctor. Do not discontinue any medications without a doctor's advice.
PrimaquineSaquinavir
Critical
How does the drug interact with Malirid 45 mg Tablet:
When Malirid 45 mg Tablet is taken with Saquinavir, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Malirid 45 mg Tablet with Saquinavir is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
PrimaquineThioridazine
Critical
How does the drug interact with Malirid 45 mg Tablet:
When Thioridazine and Malirid 45 mg Tablet are taken together, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Malirid 45 mg Tablet with Thioridazine is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
PrimaquineDronedarone
Critical
How does the drug interact with Malirid 45 mg Tablet:
When Malirid 45 mg Tablet is taken with Dronedarone, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Malirid 45 mg Tablet with Dronedarone is not advised generally as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
PrimaquineZiprasidone
Critical
How does the drug interact with Malirid 45 mg Tablet:
Taking Malirid 45 mg Tablet with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Ziprasidone with Malirid 45 mg Tablet is not recommended as it can cause an interaction, it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Adequate nutrition is the key to improvement in malaria induced weakness.
  • It is important to allow the patient to eat regularly in small amounts to tolerate the food. 
  • Increase fluid and protein intake for malaria induced weight loss.
  • Proper rest and mosquito-free premises is important for the patient to recover
  • Avoid eating fried and processed foods, junk oily and spicy foods can aggravate nausea and can disturb the digestion process in the body.
  • High fibre foods like whole-grain cereals must be avoided by malaria patients. Instead, the intake of fruits and pulses should be increased as they provide adequate nutrition

Habit Forming

No

Therapeutic Class

ANTI- MALARIALS
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Alcohol

Caution

Interaction of Malirid-45 Tablet with alcohol is unknown. It is advisable to consult your doctor before consumption.

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Pregnancy

Caution

Malirid-45 Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations, if the benefits are more than the potential risks. Please consult your doctor.

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Breast Feeding

Caution

Malirid-45 Tablet is recommended for use in breastfeeding women only after diagnostic tests are performed to confirm normal G6PD enzyme levels. Consult your doctor before using this medicine

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Driving

Caution

Malirid-45 Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

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Liver

Caution

Malirid-45 Tablet therapy is unlikely to cause liver injury in normal individuals but can trigger an acute worsening of porphyria in rare cases. Thus doctor's consultation is recommended before taking Malirid-45 Tablet

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Kidney

Caution

Malirid-45 Tablet administration impairs kidney function in a few cases, so a patient is recommended to consult a doctor before taking Malirid-45 Tablet.

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Children

Caution

Safe to use in children (<12) yet dose adjustment by a doctor will be done on the basis of age, weight and severity of the infection.

Have a query?

FAQs

Malirid-45 Tablet is used for the treatment of malaria.

No, as there may be a risk of hemolysis in patients with G6PD deficiency. Doctors consultation is mandatory.

Malirid-45 Tablet works by increasing the levels of haeme in the blood, a substance toxic to the malarial parasite. This kills the parasite and stops the infection from spreading. In this way Malirid-45 Tablet used for the prevention of relapse of malaria caused by plasmodium vivax and Plasmodium ovale strains of the parasite.

Common side effects of Malirid-45 Tablet include rash, vomiting, headache, dizziness, hives, stomach pain, nausea, abdominal pain, itching, heartburn, gastrointestinal discomfort, upper abdominal pain.

No, do not stop taking Malirid-45 Tablet. It is recommended to take this medicine for the entire prescribed duration even when symptoms improve or resolve. Failure to do so might result in drug resistance and treating any subsequent infection with the same medicine would be very difficult.

No, Malirid-45 Tablet is not safe to use in heart problems. The use of this medicine may increase the risk of irregular heart rhythms. Therefore, it should be used with caution in patients with arrhythmias or any other heart diseases. Any symptoms of palpitations, difficulty in breathing should be reported to the doctor.

Malirid-45 Tablet is contraindicated in patients taking medications that may cause haemolysis or depress the myeloid elements of the bone marrow. It should not be taken by pregnant women and acutely ill patients with conditions like granulocytopenia (rheumatoid arthritis or lupus), or those who have recently taken quinacrine, as it may increase the risk of toxicity.

You should tell your doctor if you are taking cephalosporins such as cefaclor, cephalexin, cefuroxime, penicillin, cefdinir, or cefpodoxime, levodopa, medications to treat cancer, methyldopa or quinidine, or if you are taking or planning to take vitamins, nutritional supplements, and herbal products. Let the doctor know if you have or have ever had haemolytic anaemia (a condition with an abnormally low number of RBC), rheumatoid arthritis, lupus erythematosus (a disease that occurs when the body's tissues are attacked by antibodies from its immune system), methemoglobinemia (a condition with defective red blood cells that are unable to carry oxygen to the tissues in the body), nicotinamide adenine dinucleotide (NADH) deficiency (a genetic condition), glucose-6-phosphate dehydrogenase (G6PD) deficiency (a genetic condition) and if you are pregnant or breastfeeding.

Yes, Malirid-45 Tablet is safe if it is taken in the dose and duration prescribed by the doctor. Therefore, take Malirid-45 Tablet exactly prescribed by the doctor based on your medical condition.

If you have missed the dose, take it as soon as you remember and if it's already time for the next dose, skip the missed one and take the scheduled dose. Do not double the dose.

Swallow Malirid-45 Tablet as a whole with water; do not crush or chew it. Malirid-45 Tablet should be taken with food to decrease the risk of stomach upset.

Malirid-45 Tablet should be taken exactly as prescribed by the doctor, preferably with a meal to minimize stomach discomfort. For best results, take it at the same time every day.

No, Malirid-45 Tablet is not an antibiotic. It belongs to the group of medications called antimalarials used to treat and prevent malaria caused by the Plasmodium parasite. It is also used to prevent relapse of malaria caused by Plasmodium vivax and Plasmodium ovale.

Malirid-45 Tablet may impair kidney function in a few cases. Therefore, consult the doctor before taking Malirid-45 Tablet if you have any kidney problems.

Yes, Malirid-45 Tablet may cause drowsiness as a side effect. Avoid driving and operating machinery if you feel drowsiness and there is no evidence suggesting that Malirid-45 Tablet has any effect on blood pressure.

Country of origin

India

Manufacturer/Marketer address

142 AB, Kandivli Industrial Estate, Kandivli (West), Mumbai - 400 067, Maharashtra.
Other Info - MAL0120

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

May 20, 2025 | 6:20 PM IST

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Reference

  1. https://www.webmd.com/drugs/2/drug-12232/primaquine-oral/details
  2. https://www.rxlist.com/primaquine-drug.htm#description
  3. https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/008316s023lbl.pdf
  4. https://www.drugs.com/cdi/primaquine.html
  5. https://www.medindia.net/drug-price/primaquine/primaquine-phosphate.htm

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