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compositionComposition:MEDROXYPROGESTERONE ACETATE-10MG
prescriptionPrescription Medicine
Medache Tablet 10's

Medache Tablet is used in the treatment of amenorrhea (absence of menstruation), irregular periods, uterine bleeding, endometrial hyperplasia (thickening of the uterus), and endometriosis. It works by replacing or supplementing the naturally produced female sex hormone called progesterone. This medicine may cause common side effects like headache, nausea, dizziness, hair loss, acne, unusual vaginal bleeding or spotting.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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More about the Product

Composition :

MEDROXYPROGESTERONE ACETATE-10MG

Manufacturer/Marketer :

Medpat Pharma Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Medache Tablet

Medache Tablet is used to treat heavy, painful, irregular or missed periods, absence of periods, and uterine bleeding. It is also used to treat mild to moderate endometriosis and to decrease the risk of endometrial hyperplasia (a condition that may lead to uterine cancer) while taking estrogens. Medache Tablet may also be used to prevent pregnancy.

Medache Tablet contains medroxyprogesterone acetate that works by replacing or supplementing the naturally produced female sex hormone called progesterone. Medache Tablet treats endometriosis by thinning the uterine lining, thereby preventing the spread of tissues from the uterus to other body parts. It helps prevent pregnancy by stopping the release of eggs from the ovaries (ovulation). 

Take Medache Tablet as prescribed. In some cases, you may have headache, nausea, dizziness, hair loss, acne, unusual vaginal bleeding or spotting. Most of these side effects of Medache Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Avoid taking Medache Tablet if you are pregnant, think you may be pregnant, or if you are breastfeeding. Inform your doctor if you have/had breast cancer, unusual bleeding in the vagina, liver disease, or any other health problems. Avoid smoking and alcohol consumption to prevent any unpleasant side effects. Medache Tablet may cause dizziness, so drive only if you are alert after taking Medache Tablet .

Uses of Medache Tablet

Medache Tablet is used to treat Amenorrhea, irregular periods, uterine bleeding, endometrial hyperplasia, and endometriosis. The detailed uses of Medache Tablet are as follows:

  • Menstrual Cycle Regulation: Medache Tablet helps to regulate irregular menstrual cycles, treating conditions like amenorrhea by stabilising hormonal imbalances and promoting a regular menstrual cycle.
  • Hormonal Replacement Therapy: Medache Tablet may be used for hormone replacement therapy (HRT) to alleviate symptoms of menopause, such as hot flashes and mood changes, by regulating estrogen levels.
  • Endometriosis Treatment: Medache Tablet is also used to treat endometriosis symptoms, such as painful periods and irregular cycles, by regulating hormones and reducing discomfort.
  • Treatment of Abnormal Uterine Bleeding: By controlling hormone levels and possibly lowering excessive bleeding during menstruation, Medache Tablet can help manage abnormal uterine bleeding.

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Directions for Use

  • Medache Tablet can be taken with or without food, but taking it with food helps reduce stomach upset.
  • Follow the recommended dosage and duration advised by the doctor to achieve optimal results.
  • Swallow Medache Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

Key Benefits

Medache Tablet belongs to a group of medicines called progestogens used to treat heavy, painful, irregular or missed periods, absence of periods, and uterine bleeding. It is also used to treat mild to moderate endometriosis and to decrease the risk of endometrial hyperplasia (a condition that may lead to uterine cancer) while taking estrogens. Medache Tablet may also be used to prevent pregnancy. Medache Tablet contains medroxyprogesterone acetate that works by replacing or supplementing the naturally produced female sex hormone called progesterone. Medache Tablet treats endometriosis by thinning the uterine lining, thereby preventing the spread of tissues from the uterus to other body parts. It helps prevent pregnancy by stopping the release of eggs from the ovaries (ovulation). 

How Medache Tablet Works

Medache Tablet contains medroxyprogesterone acetate that works by replacing or supplementing the naturally produced female sex hormone called progesterone. Medache Tablet treats endometriosis by thinning the uterine lining, thereby preventing the spread of tissues from the uterus to other body parts. It helps prevent pregnancy by stopping the release of eggs from the ovaries (ovulation).

Storage

Store in a cool and dry place away from sunlight
Side effects of Medache Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Use hot or cold packs on your breasts to help alleviate discomfort.
  • Choose a supportive, well-fitting bra, preferably one that has been professionally fitted.
  • Practice relaxation techniques to manage stress and anxiety that may accompany severe breast pain.
  • Limit or avoid caffeine consumption.
  • Eat a low-fat diet and focus on foods rich in complex carbohydrates.
  • Rubbing evening primrose oil on your breasts may help balance fatty acids in the cells and reduce pain.
  • Keep track of when your breast pain occurs and any other symptoms to determine if the pain is regular or not.
  • Vitamin E supplements may help reduce pain for women who experience pain linked to their menstrual cycle.
  • Over-the-counter pain relievers like acetaminophen or ibuprofen can provide relief, but be sure to consult your doctor for the correct dosage, as prolonged use may cause side effects.
Managing Medication-Triggered Thrombophlebitis (Inflammation of a vein): A Step-by-Step Guide:
  • If you have symptoms such as pain, swelling, redness, or warmth in your veins after taking medication, contact your doctor right once. Share information about your symptoms, medication regimen, and medical history.
  • Your doctor will then assess your medication regimen to determine if it's contributing to the thrombophlebitis. This assessment will help identify the best course of action to manage your condition and prevent further complications.
  • Your doctor may suggest certain diet and lifestyle changes to help manage your condition. This may include increasing your intake of foods rich in omega-3 fatty acids, staying hydrated, exercising regularly, and maintaining a healthy weight. Your doctor may also advise medications to reduce inflammation, prevent blood clots, or manage pain if necessary.
  • If your condition does not improve or persists, consult your doctor and report your condition. Your doctor will assess your progress, adjust your treatment plan if necessary, and provide appropriate advice to ensure the best possible outcome.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Keep your skin clean by gently washing your face two times daily and after sweating. Choose a mild and non-abrasive cleanser.
  • Use gentle alcohol-free skin care products. Avoid products that might irritate your skin such as exfoliants, astringents and toners.
  • Acne may also occur due to oil in the hair. Thus, if you have oily hair, shampoo more frequently than you do now and keep your hair away from face.
  • Keep your hands off your face as touching face throughout the day might worsen acne. Also, do not pick, squeeze or pop acne as it will prolong the healing process and increase the risk of dark spots and scarring.
  • Avoid tanning by applying a broad spectrum sunscreen and wearing sun-protective clothing when outdoors.

What if I have taken an overdose of Medache Tablet

Do not take more than the prescribed dose of Medache Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not use Medache Tablet if you are allergic to medroxyprogesterone acetate, or any other similar hormonal medicines, if you have/had breast cancer, venous/arterial thrombosis, liver problems, porphyria, if you are pregnant or think you may be pregnant. Tell your doctor before using Medache Tablet if you have had a heart attack, stroke, blood clot, liver problems, kidney problems, asthma (wheezing), epilepsy (seizures), diabetes, migraine, endometriosis, lupus, heart problems, thyroid, or have high calcium levels in your blood. Be cautious while driving as Medache Tablet may cause dizziness.

Drug-Drug Interactions

verifiedApollotooltip
MedroxyprogesteroneAcitretin
Critical
MedroxyprogesteroneEtretinate
Critical

Drug-Drug Interactions

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MedroxyprogesteroneAcitretin
Critical
How does the drug interact with Medache Tablet:
Coadministration of Acitretin with Medache Tablet can increase the risk and severity of birth defects when taken by a pregnant woman.

How to manage the interaction:
Taking Acitretin with Medache Tablet together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. Consult a doctor if you get pregnant while taking these medications. Do not discontinue any medications without consulting a doctor.
MedroxyprogesteroneEtretinate
Critical
How does the drug interact with Medache Tablet:
Taking Medache Tablet and Etretinate may cause severe birth defects if the mother takes the medication during pregnancy.

How to manage the interaction:
Using etretinate and Medache Tablet together is not recommended, but can be taken if prescribed by a doctor. However, if you experience unusual symptoms contact your doctor. Do not discontinue any medications without consulting a doctor.
MedroxyprogesteroneTranexamic acid
Critical
How does the drug interact with Medache Tablet:
Taking Medache Tablet acetate with Tranexamic acid may increase the risk of blood clots.

How to manage the interaction:
Taking Medache Tablet with Tranexamic acid is not recommended but can be taken if prescribed by a doctor. Consult your doctor immediately if you experience symptoms such as chest pain, shortness of breath, coughing up blood, blood in the urine, sudden loss of vision, and pain, redness, or swelling in your arm or leg. Do not stop using any medications without talking to your doctor.
MedroxyprogesteroneFosamprenavir
Severe
How does the drug interact with Medache Tablet:
Taking Medache Tablet together with fosamprenavir may decrease the effects of fosamprenavir.

How to manage the interaction:
Although there is a possible interaction between Medache Tablet and Fosamprenavir, you can take these medicines together if prescribed by your doctor. However, if you experience any unusual symptoms contact your doctor right away. Do not stop using any medications without a doctor's advice.
MedroxyprogesteroneAmprenavir
Severe
How does the drug interact with Medache Tablet:
Taking Medache Tablet with amprenavir may make amprenavir less effective.

How to manage the interaction:
There may be a possibility of interaction between Medache Tablet and Amprenavir, but it can be taken if prescribed by a doctor. If you're having any unusual symptoms, it's important to contact your doctor right away. Do not discontinue any medications without first consulting your doctor.
MedroxyprogesteroneDabrafenib
Severe
How does the drug interact with Medache Tablet:
When Dabrafenib is taken with Medache Tablet acetate, the amount of Medache Tablet acetate in the blood may decrease.

How to manage the interaction:
Co-administration of Dabrafenib with Medache Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience hot flashes(feeling of heat in the body), dryness, or unusual bleeding, don't hesitate to reach out to your doctor. Do not stop using any medications without a doctor's advice.
MedroxyprogesteroneTopiramate
Severe
How does the drug interact with Medache Tablet:
When Medache Tablet acetate is taken with Topiramate, it reduces the blood levels and effects of Medache Tablet.

How to manage the interaction:
Co-administration of Medache Tablet with Topiramate can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're taking birth control and experiencing symptoms like hot flashes, vaginal dryness, or abnormal bleeding, contact your doctor. Do not stop using any medications without talking to your doctor.
MedroxyprogesteroneGriseofulvin
Severe
How does the drug interact with Medache Tablet:
Taking griseofulvin with Medache Tablet may reduce blood levels and the effects of Medache Tablet.

How to manage the interaction:
There may be a possibility of interaction between Griseofulvin and Medache Tablet, but it can be taken if prescribed by a doctor. However, if you experience any of these symptoms like unexpected bleeding or abnormal bleeding, or if you think you might be pregnant while using birth control, it's important to contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MedroxyprogesteroneBosentan
Severe
How does the drug interact with Medache Tablet:
Taking Bosentan and Medache Tablet may, reduce the blood levels and effects of Medache Tablet.

How to manage the interaction:
Although there is a interaction between bosentan and Medache Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience hot flashes(feeling of heat in the body), dryness, or unusual bleeding, don't hesitate to reach out to your doctor. Do not stop using any medications without a doctor's advice.
MedroxyprogesteroneSugammadex
Severe
How does the drug interact with Medache Tablet:
When Medache Tablet is taken with sugammadex, the effect of Medache Tablet in the blood may decrease.

How to manage the interaction:
Taking Sugammadex with Medache Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any unusual symptoms consult your doctor immediately. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do regular exercise and physical activity to minimize hot flushes and improve sleep. Besides this, weight-bearing exercises can help in making your bone strong. Aerobic exercise, yoga, and activities like tai chi may help relax the body and mind.
  • Try to wear loose clothes before going to bed and sleep in a cool, well-ventilated room. Doing this can prevent symptoms of hot flushes and night sweats. Take minimum sleep of 8 hours. 
  • Avoid or limit intake of caffeine-containing beverages, alcohol, and spicy food, as these are known triggering agents for hot flushes.
  • Try to be stress-free to improve your mood swings due to hormonal fluctuations. 
  • Quit smoking as it will help to reduce hot flushes and your risk of developing chronic conditions like heart disease, stroke, and cancer.

Habit Forming

No

Therapeutic Class

[HORMONES]

All Substitutes & Brand Comparisons

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Alcohol

Caution

There is not enough scientific data available for Medache Tablet interaction with alcohol. Hence it is best to consult a doctor.

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Pregnancy

Unsafe

Avoid taking Medache Tablet if you are pregnant or think you may be pregnant as Medache Tablet might affect the developing baby.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Medache Tablet . Consult your doctor if you have any concerns.

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Driving

Caution

It is advised to drive with caution after taking Medache Tablet as it may cause dizziness.

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Liver

Unsafe

Medache Tablet is not recommended for people with liver problems. Consult a doctor if you have any concerns.

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Kidney

Caution

There is not enough scientific data available regarding the use of Medache Tablet in people with kidney problems. Hence it is best to consult a doctor.

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Children

Unsafe

Medache Tablet is not recommended for children below 12 years of age.

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Heart

Medache Tablet should be taken with caution in patients with heart conditions. Please inform your doctor about any existing heart problems before starting Medache Tablet .

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Geriatrics

Caution

Medache Tablet should be given with caution in elderly patients due to an increased risk of side effects. It is important to inform a healthcare professional before use.

FAQs

Medache Tablet is used to treat heavy, painful, irregular or missed periods, absence of periods, and uterine bleeding. It is also used to treat mild to moderate endometriosis and to decrease the risk of endometrial hyperplasia (a condition that may lead to uterine cancer) while taking estrogens. Medache Tablet may also be used to prevent pregnancy.

Medache Tablet contains medroxyprogesterone acetate that works by replacing or supplementing the naturally produced female sex hormone called progesterone.

Abnormal uterine bleeding, irregular or missed periods (amenorrhea), abdominal pain during pregnancy, and frequent miscarriages are the signs of low progesterone. Additionally, low progesterone levels lead to high estrogen levels, and women can have decreased sex drive, weight gain, or gallbladder problems.

Yes, Medache Tablet may cause weight gain. Eat healthy food and exercise regularly. If you feel that you are gaining a lot of weight while taking Medache Tablet , please consult your doctor.

Do not use Medache Tablet if you are allergic to medroxyprogesterone acetate, or any other similar hormonal medicines, if you have/had breast cancer, venous/arterial thrombosis, liver problems, porphyria, if you are pregnant or think you may be pregnant.

Continue taking Medache Tablet for as long as it has been prescribed by the doctor. If you experience any difficulty while taking Medache Tablet , consult a doctor.

Country of origin

India

Manufacturer/Marketer address

JWALAPUR HARIDWAR Haridwar, IN
Other Info - MED0957

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Veda MaddalaDoctor badge

Reviewed By

Veda Maddala

M Pharmacy

Last Updated

Oct 31, 2025 | 7:30 AM IST

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