Medfate O Syrup is used to treat peptic ulcers or gastrointestinal ulcers. It also treats hyperacidity, heartburn, indigestion, and gastritis (inflammation of the stomach). The stomach is usually protected from acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets eroded, which leads to complications like acidity and heartburn. A peptic ulcer is a sore on the stomach's lining or the first part of the small intestine (duodenum). Ulcers or sores of the stomach region are called gastric ulcers, while the duodenum ulcer is known as a duodenal ulcer.

Medfate O Syrup is a combination of two medicines: Sucralfate and Oxetacaine. Sucralfate is a gastrointestinal protectant that works by forming a protective barrier or coat over the ulcer so that digestive enzymes, acid and bile salts cannot further irritate the lining of the stomach duodenum. This protects the ulcer from the acid of the stomach, allowing it to heal. Besides this, Oxetacaine is a local anaesthetic that exerts a numbing effect, thereby providing relief from pain due to ulcers or acidic injury in the stomach.

It is better to take Medfate O Syrup an hour before a meal or without a meal for its best results. Your doctor will advise you on how often you take Medfate O Syrup based on your medical condition. Some people may experience common side effects like constipation, dizziness, sleepiness, dry mouth, blurred vision, and diarrhoea. Most of these side effects of Medfate O Syrup do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Medfate O Syrup or active and inactive ingredients present on it, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Medfate O Syrup. Medfate O Syrup should not be given to children as safety has not been established. Try not to stop taking Medfate O Syrup of your own. Stopping a sudden intake of Medfate O Syrup will not influence the frequency or severity of future ulceration. Avoid taking aluminium and magnesium-containing antacids with Medfate O Syrup. Aluminium-containing antacids and Medfate O Syrup could lead to constipation and intestinal obstruction, whereas magnesium-containing antacids might cause diarrhoea.  Avoid consuming alcohol along with Medfate O Syrup as it could lead to increased acidity.

Medfate O Syrup belongs to a group of anti-ulcerants used to treat acidity, heartburn, gas and stomach ulcers. Medfate O Syrup is a combination of two medicines: Sucralfate (anti-ulcer) and Oxetacaine (Local anaesthetic). Sucralfate works by forming a protective barrier or coat over the ulcer to pepsin and bile and inhibiting gastric acid diffusion. This protects the ulcer from the acid of the stomach, allowing it to heal. It exhibits a cytoprotective effect and forms a viscous, adhesive barrier on the intact intestinal mucosa and stomach surface. It also stimulates the synthesis and release of gastric mucosal prostaglandins and bicarbonate and the epidermal growth factor that stimulates healing and formation of new healthy skin. On the other hand, Oxetacaine exerts a numbing effect, thereby providing relief from pain due to ulcers or acidic injury in the stomach. It does not lose its activity even in strongly acidic conditions and provides prolonged anaesthetic action.

You should avoid taking Medfate O Syrup if you are allergic to Medfate O Syrup or other ingredients present in it.  Inform your doctor before taking Medfate O Syrup if you have a history of appendicitis, blockage of the bowel, rectal bleeding, kidney problems, low-magnesium diet, or if you have undergone recent bowel surgery. Caution is required before giving Medfate O Syrup to elderly patients. Sucralfate in Medfate O Syrup contains aluminium, which is normally removed by your kidney. Therefore, older adults and people who have kidney problems may be at greater risk for developing high aluminium levels while using this drug with other products that contain aluminium (e.g. antacids). Do not take Medfate O Syrup if you are pregnant or breastfeeding unless prescribed by the doctor. The safety and effectiveness in children are not established, please consult your doctor before giving them Medfate O Syrup. Avoid consuming alcohol along with Medfate O Syrup as it could lead to increased acidity.