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compositionComposition:MEFENAMIC ACID-100MG
prescription
Prescription Medicine
info
Mef-100 Oral Suspension 60 ml

Mef-100 Oral Suspension 60 ml is used to provide relief from mild to moderate pain and inflammation associated with muscular, rheumatic, and arthritic disorders, headache, trauma, dental pain, and pain after surgery or childbirth. Additionally, it is used to relieve period pain and premenstrual syndrome symptoms (PMS) and manage excessively heavy periods. It contains Mefenamic acid, which works by blocking the effect of chemical messengers that cause pain and inflammation. In some cases, you may experience certain common side effects such as abdominal pain, nausea, vomiting, diarrhoea, heartburn and indigestion. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

MEFENAMIC ACID-100MG

Manufacturer/Marketer :

Capital Pharma

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Mef-100 Oral Suspension 60 ml

Mef-100 Oral Suspension 60 ml is an oral medication widely prescribed to provide short-term relief from mild to moderate pain. It is clinically used to manage short-term pain such as dental pain, muscle aches, headaches, and menstrual cramps. By targeting the source of discomfort, this medicine helps you manage physical pain and restore normal daily function.

This medication is typically taken up to three times a day, but it should only be used consistently for the exact duration recommended by your doctor. It is highly recommended to take each dose with food or a glass of milk to protect your stomach lining from irritation. Making minor adjustments, such as using warm compresses for menstrual pain or avoiding excessive physical strain during recovery, can further support your progress.

While taking Mef-100 Oral Suspension 60 ml, you may experience mild side effects like heartburn, nausea, or mild indigestion. However, if you experience rare but serious signs such as severe stomach pain, black stools, or unusual bleeding, you must stop taking the medication and consult your doctor immediately.

Before starting this medication, talk to your doctor if you have a history of high blood pressure, heart conditions, asthma, or kidney disease. Do not take this if you have active stomach ulcers, severe heart failure or if you have previously experienced severe allergic reactions like asthma or rashes after taking aspirin or similar pain relievers.

This medication can interact with other substances, such as blood thinners or alcohol, which may significantly increase your risk of stomach bleeding. If you are pregnant, breastfeeding, or an elderly individual, it is crucial to consult your doctor or pharmacist before using this medicine, as special precautions or alternative options may be required.

Uses of Mef-100 Oral Suspension 60 ml

Mef-100 Oral Suspension 60 ml is used to provide short-term relief from mild to moderate pain. The detailed uses of Mef-100 Oral Suspension 60 ml are as follows:

  • Menstrual pain and heavy bleeding: Mef-100 Oral Suspension 60 ml helps reduce severe pelvic cramping and manages heavy blood flow during your menstrual cycle.
  • Mild to moderate pain: It provides effective relief from short-term painful conditions, including toothaches, muscle strains, headaches, and pain after minor surgical procedures.
  • Joint and muscle inflammation: It helps ease discomfort, swelling, and stiffness caused by temporary inflammation in the joints or soft tissues.
     

Key Benefits

Mef-100 Oral Suspension 60 ml helps relieve pain and inflammation, improving comfort and supporting recovery from a variety of painful conditions. In certain conditions, it may also help reduce excessive menstrual bleeding, providing comprehensive symptom relief.

  • Helps Relieve Pain and Inflammation: By reducing the production of substances that cause pain and inflammation, Mef-100 Oral Suspension 60 ml helps relieve discomfort associated with injuries, dental procedures, musculoskeletal conditions, and other painful disorders.
  • Supports Comfort During Menstrual Periods: Mef-100 Oral Suspension 60 ml helps reduce menstrual cramps and, where indicated, may also help decrease excessive menstrual bleeding, making periods more comfortable and manageable.
  • Improves Daily Comfort and Recovery: By effectively controlling pain, Mef-100 Oral Suspension 60 ml helps improve mobility, supports better sleep, and allows you to carry out daily activities more comfortably while recovering from pain or inflammation.
     
Side effects of Mef-100 Oral Suspension 60 ml
  • High levels of liver enzymes need immediate medical attention.
  • Watch your diet and consume low-fat foods, like green leafy vegetables, fish, whole grains, nuts, etc.
  • Regularly do strengthening exercises to control your cholesterol levels.
  • Avoid drinking alcohol as it can affect your liver.
  • Focus on losing weight as it can help control cholesterol and maintain liver enzymes.
  • Practice yoga and meditation to improve liver functioning and overall health.

Directions for Use

  • Mef-100 Oral Suspension 60 ml can be taken with food or as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Tablet/capsule: Swallow it as a whole with a glass of water.
  • Dispersible tablet: Dissolve the tablet in a glass of water and consume it immediately.
  • Do not break, chew, or crush it.

How Mef-100 Oral Suspension 60 ml Works

Mef-100 Oral Suspension 60 ml contains mefenamic acid. It belongs to a class of medications known as non-steroidal anti-inflammatory drugs (NSAIDs). It works by blocking the action of specific enzymes in your body called cyclooxygenase (COX) enzymes. These enzymes are responsible for producing prostaglandins, which are natural chemicals that trigger pain, swelling, and inflammation at injury sites or during menstruation. By stopping the production of these chemicals, the medication effectively reduces both the pain signal and the swelling in the affected tissues.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Mef-100 Oral Suspension 60 ml as it may increase drowsiness. It can also increase the risk of stomach bleeding.

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Pregnancy

Caution

Mef-100 Oral Suspension 60 ml belongs to pregnancy category C. Please consult your doctor if you are pregnant or planning to become pregnant. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Mef-100 Oral Suspension 60 ml may pass into breastmilk. Consult your doctor if you are breastfeeding.

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Driving

Caution

Mef-100 Oral Suspension 60 ml may cause dizziness and drowsiness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Please consult your doctor. Your doctor will recommend it based on your child's condition.

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Heart

Unsafe

Mef-100 Oral Suspension 60 ml is not recommended for use in cardiac patients due to the cardiovascular effects.

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Geriatrics

Caution

Elderly patients may require caution and dose adjustments, as Mef-100 Oral Suspension 60 ml may increase the risk of side effects.

What if I have taken an overdose of Mef-100 Oral Suspension 60 ml

If you suspect an overdose, seek immediate emergency medical attention. Overdose symptoms may include severe stomach pain, extreme drowsiness, nausea, vomiting, or slowed breathing.

Diet & Lifestyle Advise

  • Drink plenty of fluids, especially water, throughout the day to support your kidneys and maintain optimal hydration while taking this medication.
  • Avoid drinking alcohol, as it can significantly increase the risk of stomach irritation, ulcers, and bleeding when combined with this medicine.
  • If you are taking this for menstrual pain, applying a warm heating pad to your lower abdomen can help relax your muscles and work alongside the medication to ease discomfort.
  • Eat small, frequent, and bland meals to protect your digestive tract and reduce the likelihood of experiencing an upset stomach or acid reflux.
     

Have a query?

How Soon It Starts Working

The time required for Mef-100 Oral Suspension 60 ml to start to work: The time required for Mef-100 Oral Suspension 60 ml to start to work is 20 to 30 minutes after administration. The time for which the effects of Mef-100 Oral Suspension 60 ml last: The effect of Mef-100 Oral Suspension 60 ml lasts for 4 to 6 hours.

What if you forget to take Mef-100 Oral Suspension 60 ml

If you miss a dose, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and continue with your normal schedule. Do not take a double dose to make up for a missed one.

Storage

•Store Mef-100 Oral Suspension 60 ml tablets or capsules at room temperature, ideally between 20°C and 25°C (68°F to 77°F). •Keep the medication inside its original blister pack or container to protect it from moisture and direct light.

Drug Warnings

  • Avoid taking this medication alongside other non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen, naproxen, or high-dose aspirin, as this increases your risk of severe stomach issues.
  • Remain upright for at least 15 to 30 minutes after taking your dose to prevent oesophageal irritation or difficulty swallowing.
  • If you are scheduled for any surgical or dental procedures, inform your healthcare provider that you are taking this medication, as it may affect blood clotting.
  • If your doctor prescribes this medicine for more than a few days, attend all scheduled appointments for blood tests to monitor your kidney and liver function.
  • Stop taking the medication immediately at the first sign of a skin rash, skin peeling, or mouth sores, and contact your doctor right away.
     

Drug-Drug Interactions

verifiedApollotooltip
  • Blood thinners (such as warfarin): May significantly increase the risk of serious stomach and intestinal bleeding.
  • Other NSAIDs or aspirin: Increases the likelihood of developing painful stomach ulcers or gastrointestinal bleeding.
  • Blood pressure medications (such as ACE inhibitors or beta-blockers): Mef-100 Oral Suspension 60 ml can make these blood pressure drugs less effective and may increase the risk of kidney damage.
  • Lithium: May raise the levels of lithium in your blood to toxic levels, requiring close monitoring.
  • Diuretics (water pills): Can reduce their effectiveness and increase the strain on your kidneys.
     
Mefenamic acidMeloxicam
Critical
Mefenamic acidKetorolac
Critical

Drug-Drug Interactions

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Mefenamic acidMeloxicam
Critical
How does the drug interact with Mef-100 Oral Suspension 60 ml:
Co-administration of Mef-100 Oral Suspension 60 ml with Meloxicam together can increase the risk or severity of bleeding.

How to manage the interaction:
Taking Mef-100 Oral Suspension 60 ml with Meloxicam together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking a doctor.
Mefenamic acidKetorolac
Critical
How does the drug interact with Mef-100 Oral Suspension 60 ml:
Coadministration of Mef-100 Oral Suspension 60 ml with Ketorolac can increase the risk or severity of gastric bleeding and ulcers.

How to manage the interaction:
Taking Mef-100 Oral Suspension 60 ml with Ketorolac together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidPrasugrel
Severe
How does the drug interact with Mef-100 Oral Suspension 60 ml:
Co-administration of Mef-100 Oral Suspension 60 ml with Prasugrel can increase the risk or severity of gastric bleeding, ulceration, and rarely, perforation leading to serious blood loss.

How to manage the interaction:
Taking Mef-100 Oral Suspension 60 ml with Prasugrel together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidCabozantinib
Severe
How does the drug interact with Mef-100 Oral Suspension 60 ml:
Using cabozantinib together with Mef-100 Oral Suspension 60 ml may increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Mef-100 Oral Suspension 60 ml and Cabozantinib, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms like blood clotting problems, excessive bleeding, or severe headaches, it's best to contact a doctor right away. They can help address any complications and provide the necessary support. Do not stop using any medications without talking to a doctor.
Mefenamic acidLeflunomide
Severe
How does the drug interact with Mef-100 Oral Suspension 60 ml:
Coadministration of Mef-100 Oral Suspension 60 ml with Leflunomide can increase the risk or severity of liver disease.

How to manage the interaction:
Taking Mef-100 Oral Suspension 60 ml with Leflunomide together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Mefenamic acidDanaparoid
Severe
How does the drug interact with Mef-100 Oral Suspension 60 ml:
Using danaparoid together with Mef-100 Oral Suspension 60 ml can increase the risk of bleeding complications.

How to manage the interaction:
There may be a possibility of interaction between Mef-100 Oral Suspension 60 ml and Danaparoid, but it can be taken if prescribed by a doctor. If you notice any of these signs - bruising, swelling, vomiting, headache, dizziness, weakness, bleeding, or blood in your urine or stools, it's important to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
Mefenamic acidEdoxaban
Severe
How does the drug interact with Mef-100 Oral Suspension 60 ml:
Using Edoxaban together with Mef-100 Oral Suspension 60 ml may increase the risk of bleeding and hemorrhage.

How to manage the interaction:
Although taking Mef-100 Oral Suspension 60 ml and Edoxaban together can cause an interaction, it can be taken if your doctor has suggested it. If you notice any of these signs, it's important to contact a doctor right away - problems with bleeding, dizziness, black or tarry stools, severe headache, weakness, or vomiting. Do not stop using any medications without talking to a doctor.
Mefenamic acidWarfarin
Severe
How does the drug interact with Mef-100 Oral Suspension 60 ml:
Coadministration of Mef-100 Oral Suspension 60 ml with Warfarin can increase the risk of bleeding.

How to manage the interaction:
Taking Mef-100 Oral Suspension 60 ml with Warfarin together can result in an interaction, it can be taken if a doctor has advised it. However, if you notice unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor immediately. Do not stop using any medications without consulting a doctor.
Mefenamic acidHuman immunoglobulin
Severe
How does the drug interact with Mef-100 Oral Suspension 60 ml:
Taking Human immunoglobulin with Mef-100 Oral Suspension 60 ml, may raise the risk of kidney problems.

How to manage the interaction:
There may be a possibility of interaction between Human immunoglobulin and Mef-100 Oral Suspension 60 ml, but it can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
Mefenamic acidDeferasirox
Severe
How does the drug interact with Mef-100 Oral Suspension 60 ml:
Coadministration of Mef-100 Oral Suspension 60 ml with Deferasirox can increase the risk or severity of gastric bleeding.

How to manage the interaction:
Taking Mef-100 Oral Suspension 60 ml with Deferasirox together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of increased or decreased urination, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Combined use greatly increases the risk of stomach bleeding and irritation of the stomach lining.
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANALGESICS]

FAQs

Mef-100 Oral Suspension 60 ml is used to provide relief from mild to moderate pain and inflammation associated with muscular, rheumatic, and arthritic disorders, headache, trauma, dental pain, and pain after surgery or childbirth. Additionally, it is used to relieve period pain and premenstrual syndrome symptoms (PMS) and manage excessively heavy periods.
Mef-100 Oral Suspension 60 ml works by blocking the chemical messengers that are responsible for pain and inflammation. Thereby, Mef-100 Oral Suspension 60 ml provides relief from pain and inflammation.
Mef-100 Oral Suspension 60 ml is generally prescribed for short-term use. Do not take Mef-100 Oral Suspension 60 ml for longer durations as it might increase the risk of heart problems and stomach bleeding.
Mef-100 Oral Suspension 60 ml is used to relieve menstrual (period) pain, symptoms of premenstrual syndrome (PMS), and management of excessively heavy periods. Take only as prescribed by the doctor.
Avoid taking Mef-100 Oral Suspension 60 ml if you have stomach ulcers. Mef-100 Oral Suspension 60 ml might increase the risk of stomach ulcers, perforation of the stomach and intestinal bleeding with higher doses.
Diarrhoea might be a side-effect of Mef-100 Oral Suspension 60 ml. Drink plenty of fluids and eat food rich in fibre. Consult your doctor if you experience excessive diarrhoea or if you find blood in stools.
It is considered harmful for patients with severe kidney problems and those experiencing active intravascular clotting, which obstructs blood flow due to blood clots.
Store Mef-100 Oral Suspension 60 ml at room temperature, away from sunlight. Keep the Mef-100 Oral Suspension 60 ml out of reach of children.
No, Mef-100 Oral Suspension 60 ml doesn’t act as a contraceptive; it is used to relieve mild to moderate pain and inflammation.
Mef-100 Oral Suspension 60 ml should be taken only as it is prescribed by the doctor. Do not self-medicate and do not recommend Mef-100 Oral Suspension 60 ml to others with the same condition.
If the dose of Mef-100 Oral Suspension 60 ml is missed, take the missed dose as soon as you remember. If it is time for the next dose, skip the missed dose and continue taking the regular dose. Avoid taking a double dose to make up for the missed one.
Mef-100 Oral Suspension 60 ml is used for a short time, not more than 3-5 days of your menstrual cycle. However, the duration for your use will be advised by the doctor. Do not self-medicate.
It is highly recommended to take Mef-100 Oral Suspension 60 ml with food or a glass of milk. Taking it on an empty stomach can increase the risk of stomach upset, indigestion, or irritation. If you still experience discomfort, talk to your doctor.
You should avoid taking Mef-100 Oral Suspension 60 ml during pregnancy, particularly in the third trimester, as it can harm the unborn baby or cause complications during delivery. If you are pregnant or planning to become pregnant, talk to your doctor.
Taking Mef-100 Oral Suspension 60 ml with paracetamol may occasionally be recommended by a doctor for short-term pain management, as they work differently. However, you should never combine pain relievers without professional advice. Talk to your doctor or pharmacist.
Yes, some people may experience drowsiness, dizziness, or lightheadedness while taking Mef-100 Oral Suspension 60 ml. Avoid driving or operating machinery until you know how this medication affects you. If these symptoms persist, talk to your doctor.
It is highly advised to avoid drinking alcohol while taking Mef-100 Oral Suspension 60 ml. Alcohol can significantly increase your risk of developing stomach ulcers or severe digestive tract bleeding. If you have concerns, talk to your doctor.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. U.S. Food and Drug Administration (FDA). 015034S040Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026] Check here
  2. MedlinePlus. A681028 Patient Information Monograph. Bethesda, MD: U.S. National Library of Medicine (NLM); 2025. [Accessed on 02 Jun. 2026] Check here
  3. Drugs.com Clinical Review Team. Mefenamic Acid Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  4. Ema. Mefenamic Acid . [[Accessed on 20 Nov].2025] : Check here
  5. Webmd. Mefenamic Acid. [[Accessed on 20 Nov].2025] : Check here
  6. mayoclinic. mefennamic acid . [[Accessed on 20 Nov].2025]: Check here
  7. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Mefenamic Acid. [Updated 2025 Nov 20]:Check here

Country of origin

India

Manufacturer/Marketer address

No 28, Lakshmipuram Main Road, Poombukar Nagar, Edayarpalayam, Coimbatore - 641038
Other Info - MEF0291

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