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Megazine Syrup is used to treat acidity, heartburn, gas, and stomach ulcers. It works by neutralising excess stomach acid. It decreases gas bubbles surface tension, thereby facilitating gas expulsion through flatus or belching (burping). It also prevents the accumulation and formation of gas in the digestive tract. Also, it exerts a numbing effect, thereby provides relief from pain due to ulcers or acidic injury in the stomach. In some cases, it may cause common side effects such as constipation, diarrhoea, and intestinal pain. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Megazine Syrup

Megazine Syrup is an oral suspension prescribed to relieve painful symptoms of stomach ulcers, acid reflux, and excess gas. It works by quickly lowering the acid levels in your stomach, numbing the irritated areas of your digestive tract, and breaking down trapped gas. This combined approach provides fast, soothing relief from stomach burning and abdominal bloating.

For the best results, you should take Megazine Syrup consistently at the times recommended by your doctor, which is typically after meals and right before bedtime. It is usually taken about one hour after meals and at bedtime, and you should avoid drinking water immediately after taking your dose so the medicine can coat your stomach lining effectively. Simple lifestyle changes, such as eating smaller portions and staying upright after eating, can also support your treatment.

Most patients tolerate this medicine very well, though some may experience mild and temporary side effects like constipation or diarrhoea. These symptoms usually resolve on their own as your body adapts to the medicine. However, if you develop severe abdominal pain, persistent vomiting, or signs of a serious allergic reaction, you must consult your doctor immediately.

Before you begin taking Megazine Syrup, you should talk to your doctor if you have kidney problems or are on a magnesium-restricted diet. Do not take this medicine if you have severe kidney failure or if you have a known allergy to any of its ingredients. Your doctor will evaluate your medical history to ensure this is the safest treatment for you.

This suspension can interfere with how your body absorbs other medicines, meaning you may need to space out your doses. Avoid drinking alcohol or smoking while using Megazine Syrup, as both can irritate your stomach lining and make your symptoms worse. If you are pregnant, breastfeeding, or managing health conditions as an older adult, consult your doctor or pharmacist before starting this medicine.

Uses of Megazine Syrup

Megazine Syrup is used to relieve conditions associated with excess stomach acid, irritation of the digestive tract, and gas-related discomfort. The following are some of the common conditions for which this medicine may be recommended:

  • Heartburn and Acid Reflux: Megazine Syrup helps by neutralising excess stomach acid and protecting the food pipe from acid irritation, relieving the burning sensation in your chest.
  • Stomach and Duodenal Ulcers: It provides relief from ulcer pain by temporarily numbing the stomach lining and lowering acid levels, allowing the tissues to heal.
  • Gas and Bloating: It breaks down gas bubbles in the stomach and gut, making them easier to pass and reducing painful abdominal pressure.
  • Oesophagitis: It helps soothe inflammation in the food pipe by preventing stomach acid from rising and irritating the sensitive tissues.
     

Key Benefits

By reducing stomach acid, soothing irritated tissues, relieving pain, and helping eliminate trapped gas, Megazine Syrup offers several important benefits, including:

  • Rapid Pain Relief: The local anaesthetic component in Megazine Syrup quickly numbs the sensitive, irritated lining of your stomach and food pipe, providing fast relief from intense burning and ulcer pain.
  • Effective Acid Balancing: It works as an antacid shield, neutralising high acid levels in the stomach almost immediately to prevent heartburn from worsening.
  • Gas Pressure Reduction: By merging small, trapped gas bubbles into larger ones, the medicine allows your body to eliminate gas naturally, relieving uncomfortable bloating and stretching in your abdomen.
  • Protective Coating: The thick suspension directly coats the irritated walls of your digestive tract, acting as a physical barrier that protects raw areas and promotes natural healing.
     

Directions for Use

  • Megazine Syrup can be taken with or without food as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Measure the advised dose using the measuring cup/dosing syringe and take it orally.
  • Shake the bottle well before use.

How Megazine Syrup Works

Megazine Syrup utilises a combination of three ingredients that work together to target acid, pain, and gas simultaneously. Magaldrate acts as a fast-acting antacid. It reacts with excess hydrochloric acid in the stomach and helps buffer stomach acidity, maintaining the stomach's pH within a comfortable range without completely eliminating acid or causing a sudden rebound in acid production. Oxetacaine is a strong local anaesthetic. Unlike many other numbing agents, it remains highly effective even in the highly acidic environment of the stomach. It numbs the raw, irritated lining of the stomach and oesophagus, which rapidly quietens severe burning sensations and ulcer pain. Simethicone is an anti-foaming agent that targets gas. It works by changing the surface tension of tiny gas bubbles trapped in your stomach and intestines. This causes them to come together into larger bubbles, which can be passed more easily as a burp or flatus, quickly relieving abdominal pressure.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Megazine Syrup. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.

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Pregnancy

Caution

Please consult your doctor before taking Megazine Syrup if you are pregnant.

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Breast Feeding

Caution

Consult your doctor before taking Megazine Syrup; your doctor will decide whether Megazine Syrup can be taken by breastfeeding mothers or not.

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Driving

Caution

Megazine Syrup does not affect your ability to drive.

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Liver

Caution

Consult your doctor before taking Megazine Syrup if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Consult your doctor before taking Megazine Syrup if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Megazine Syrup should not be given to children as safety and effectiveness were not established.

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Heart

Caution

Megazine Syrup can generally be used in patients with heart problems, but only under close medical supervision.

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Geriatrics

Caution

Megazine Syrup should be taken with caution in geriatric patients. Please inform your doctor before using Megazine Syrup.

What if I have taken an overdose of Megazine Syrup

If you suspect an overdose, seek immediate medical attention or contact a local poison control centre. Symptoms of an overdose may include severe diarrhoea, muscle weakness, or extreme sleepiness due to mineral imbalances.

Diet & Lifestyle Advise

  • Eat Smaller Meals: Eat smaller, more frequent meals throughout the day rather than three large meals to avoid overloading your stomach and triggering acid production.
  • Avoid Trigger Foods: Identify and limit trigger foods that aggravate reflux and gas, such as spicy, fried, or highly acidic foods, chocolate, caffeine, and carbonated drinks.
  • Stay Upright After Eating: Avoid lying down, bending over, or doing heavy physical activity for at least two to three hours after eating.
  • Elevate the Head of Your Bed: Elevate the head of your bed by 6 to 9 inches using blocks or a wedge pillow to prevent stomach acid from travelling up into your throat while you sleep.
  • Wear Loose-Fitting Clothing: Wear loose-fitting clothes around your midsection to reduce pressure on your abdomen, which can force acid upward.
     

Have a query?

How Soon It Starts Working

The time required for Megazine Syrup to start to work: The time required for Megazine Syrup to show its action is not clinically established. The time for which the effects of Megazine Syrup last: The duration of action for Megazine Syrup is not clinically established.

What if you forget to take Megazine Syrup

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and return to your regular timing. Do not take a double dose to make up for a missed one.

Storage

•Store Megazine Syrup at room temperature, ideally between 15°C and 30°C (59°F to 86°F). . •Keep the bottle tightly closed when not in use to protect the liquid from air and moisture.

Drug Warnings

  • Inspect Before Use: Always visually inspect the liquid before taking it; do not use the medicine if you notice clumps, discolouration, or foreign particles that do not disappear after shaking.
  • Avoid Prolonged Self-Treatment: Never take this medicine continuously for more than two weeks unless your doctor has specifically instructed you to do so, as it may mask more serious stomach conditions.
  • Separate From Other Medicines: Avoid taking other oral medicines within 2 hours of taking Megazine Syrup, because the antacid can block your body from properly absorbing those medications.
  • Monitor Kidney Health: If you have a history of kidney disease, monitor your health closely and attend all follow-up appointments to have your blood mineral levels checked.
  • Do Not Share Medication: Do not share this medicine with anyone else, even if they have identical symptoms of heartburn or stomach pain.
     

verifiedApollotooltip

Megazine Syrup can affect the absorption of several medicines, particularly antibiotics, iron products, heart medications, and thyroid treatments, including:

  • Antibiotics (such as tetracyclines and fluoroquinolones): Megazine Syrup can bind to these antibiotics in your stomach, preventing them from being absorbed. Take your antibiotic at least 2 hours before or 4 to 6 hours after taking this suspension.
  • Iron Supplements: This medicine can reduce how much iron your body absorbs. Space these treatments several hours apart.
  • Heart Medications (such as digoxin): This suspension may lower the absorption and effectiveness of digoxin. Consult your doctor to monitor your medication levels closely.
  • Thyroid Hormones (such as levothyroxine): Antacids can interfere with your thyroid medication. Ensure you space these doses at least 4 hours apart.
     

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verifiedApollotooltip

Certain foods and beverages may affect the way the ingredients in this medicine are absorbed and processed by the body, including:

  • Citrus Fruits and Juices: Consuming citrus fruits or juices at the same time as, or shortly after, taking this medicine may increase the absorption of aluminium from the antacid component. This is primarily a concern for people with kidney disease or those using the medicine frequently. It does not mean citrus foods must be avoided completely at other times of the day.

 

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTACIDS, ANTIULCERANTS]

FAQs

Megazine Syrup is used to treat acidity, heartburn, gas, and stomach ulcers.
Megazine Syrup is a combination of three drugs: Magaldrate, Simethicone, and Oxetacaine. Magaldrate works by neutralising excess stomach acid. Simethicone works by decreasing gas bubbles' surface tension, thereby facilitating gas expulsion through flatus or belching (burping). It also prevents accumulation and formation of gas in the digestive tract. Oxetacaine exerts a numbing effect, thereby provides relief from pain due to ulcers or acidic injury in the stomach.
Avoid lying down immediately after meals to prevent acidity. Raise the head of the bed 10-20cm by putting a pillow so that the head and chest are above the waist. This prevents acid reflux.
Avoid taking aluminium and magnesium-containing antacids with Megazine Syrup. Aluminium containing antacids and Megazine Syrup could lead to constipation and intestinal obstruction, whereas magnesium-containing antacids might cause diarrhoea.
Taking higher than the recommended dose of Megazine Syrup will not be more effective rather it may cause side effects. Always take the dose as prescribed by the doctor based on your medical condition.
If you miss a dose of Megazine Syrup, take it as soon as possible. However, if it is almost time for your next dose, skip the missed one and take the scheduled dose. Do not double the dose.
Yes, the use of Megazine Syrup may cause constipation as a side effect. If you experience constipation, you can manage it by drinking plenty of water, exercising regularly and eating fibre-rich food.
Megazine Syrup should be stored in a cool and dry place away from sunlight. Keep it out of sight and reach of children.
The side effects of Megazine Syrup include diarrhoea, intestinal pain and constipation. Consult the doctor if any of these side effects persist or worsen.
Yes, you can take Megazine Syrup on an empty stomach to get fast relief from sudden pain or burning. However, for continuous symptom management, it is typically recommended to take it about one hour after meals and at bedtime. Talk to your doctor about the best schedule for your needs.
It is best to avoid drinking water or eating food for at least 15 to 30 minutes after taking Megazine Syrup. This allows the liquid suspension to coat your esophagus and stomach lining properly, ensuring the local anaesthetic and protective ingredients can work effectively.
You should not take Megazine Syrup during pregnancy unless your doctor specifically advises it. While some mild antacids are considered safe, the active anaesthetic ingredient in this product requires a professional medical evaluation to ensure safety for you and your baby.
You must shake the bottle because Megazine Syrup is a suspension, meaning the active ingredients can settle to the bottom over time. Shaking the bottle ensures the ingredients are evenly mixed so that every dose you measure contains the correct, safe, and effective amount of medicine.
Yes, Megazine Syrup can interact with several medications, including certain antibiotics, thyroid hormones, and iron supplements, by reducing how well your body absorbs them. To avoid this, take your other oral medicines at least 2 hours before or after taking this suspension.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India
Other Info - ME33932
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