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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Melleril 100mg Tablet is used to treat schizophrenia and bipolar disorder (manic depression). It contains Thioridazine which works by decreasing abnormal excitement in the brain. In some cases, this medicine may cause side effects such as sleepiness, dry mouth, abnormal voluntary movements, weight gain, urinary retention, constipation, muscle stiffness, and tremor. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Whats That

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Composition :

THIORIDAZINE-100MG

Manufacturer/Marketer :

Novartis India Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Melleril 100mg Tablet

Melleril 100mg Tablet is used to treat schizophrenia or psychosis and bipolar disorder (manic depression). Schizophrenia is characterized by hallucinations symptoms (seeing or hearing things that are not real) and delusions (wrong beliefs). Manic episodes of excitement or depression characterize bipolar disorder. Melleril 100mg Tablet prevents the occurrence of these symptoms. 

Melleril 100mg Tablet contains ‘Thioridazine,’ which is an antipsychotic drug. It acts by blocking dopamine, a neurotransmitter in the brain responsible for developing schizophrenia and bipolar disorder symptoms. Melleril 100mg Tablet rebalances dopamine to improve thinking, mood and behaviour. It also blocks the other natural substance receptors in the brain, such as histamine and muscarinic, thereby preventing nausea and vomiting.

Take Melleril 100mg Tablet as prescribed by your doctor. You are advised to take Melleril 100mg Tablet as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience common side effects such as sleepiness, orthostatic hypotension (sudden lowering of blood pressure on standing), dry mouth, abnormality of voluntary movements, weight gain, urinary retention, constipation, muscle stiffness, and tremor. Most of these side effects of Melleril 100mg Tablet do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.

Do not take Melleril 100mg Tablet if you are allergic to Thioridazine or any other ingredients present in it. Before taking Melleril 100mg Tablet, talk to your doctor if you or your family have a history of blood clots, stroke or heart diseases and if you are above 65 years old and have a history of dementia (memory loss). Melleril 100mg Tablet is not recommended during pregnancy as it may affect the unborn baby. Tell your doctor if you are breastfeeding before taking Melleril 100mg Tablet. It is not recommended for use in children under 1 year of age. Melleril 100mg Tablet contains lactose, so it should not be given to people who are intolerant to some sugars. Please do not stop taking Melleril 100mg Tablet without your doctor’s advice, as it may lead to withdrawal symptoms.

Uses of Melleril 100mg Tablet

Treatment of Schizophrenia (mental illness), Bipolar disorder (manic depression).

Directions for Use

Take a Melleril 100mg Tablet with a meal. You are advised to take Melleril 100mg Tablet for as long as your doctor has prescribed, depending on your medical condition.

Medicinal Benefits

Melleril 100mg Tablet works by helping to restore the balance of certain natural substances in the brain. The key action of Melleril 100mg Tablet is to block the dopamine receptors (D2) in the brain and correct dopamine's overactivity. Altogether, Melleril 100mg Tablet may help decrease hallucinations and help you think more clearly and positively about yourself, feel less agitated and take a more active part in everyday life. On the other hand, it also blocks histamine H1 and muscarinic M1 receptors in the vomiting centre, thereby preventing nausea and vomiting.

How Melleril 100mg Tablet Works

Melleril 100mg Tablet contains ‘Thioridazine,’ which is an antipsychotic drug. It acts by blocking dopamine, a neurotransmitter in the brain responsible for developing schizophrenia and bipolar disorder symptoms. Melleril 100mg Tablet rebalances dopamine to improve thinking, mood and behaviour. It also blocks the other natural substance receptors in the brain, such as histamine and muscarinic, thereby preventing nausea and vomiting.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Melleril 100mg Tablet

Take Melleril 100mg Tablet only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include blurred vision, drooling, nasal congestion, dry mouth, yellow eyes, vision colour changes, rapid/irregular/slow heart rate, high/low blood pressure, difficulty breathing, constipation, nausea, loss of appetite, dizziness, drowsiness, seizures, tremors, weakness, fever, muscle spasms/stiffness, low body temperature and difficulty walking. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take Melleril 100mg Tablet if you are allergic (hypersensitive) to Melleril 100mg Tablet or any ingredients present in it. Please consult your doctor before taking Melleril 100mg Tablet if you are pregnant or planning to conceive and breastfeed. Elderly patients (above 65 years) with dementia-related psychosis (memory loss) treated with antipsychotic drugs are at increased risk of death. Melleril 100mg Tablet injection is not recommended for treating patients with dementia-related psychosis. Do not abruptly stop taking the medication, as it may cause withdrawal symptoms, especially suicidal thoughts in young adults. If you are an asthmatic patient, please inform your doctor before taking a Melleril 100mg Tablet injection, as it may cause life-threatening allergic-type reactions, including anaphylactic symptoms. Before taking Melleril 100mg Tablet, talk to your doctor if you have a history of blood clots, alcohol or drug abuse, fits (seizures), Parkinson's disease, hypothyroidism (reduced activity of the thyroid gland), stroke or heart diseases and glaucoma (increased pressure in the eye).

Diet & Lifestyle Advise

  • Monitor your mood. Keep track of your mood regularly, including factors such as sleep, medicine and activities that can impact your mood. Exercise daily.
  • Exercise is nice to relieve tension. It can also avoid the weight gain that can be a side effect of your bipolar medication.
  • You may also practice calming techniques such as meditation and deep breathing exercises.
  • Get some normal sleep. Having enough sleep will help to stabilize your mood.
  • Eat a healthy diet. Certain foods may affect your mood more than others. Consider keeping a food log to track what you eat and how certain foods make you feel. Talk to your doctor or nutritionist about foods that may help stabilize your mood.
  • Stay optimistic. It will take time for your symptoms to improve after you start bipolar therapy, but you will feel relaxed knowing that you will get better and that the worst is most definitely behind you.
  • A person should take a healthy diet that includes lots of fruits and vegetables, lean meats, skinless poultry, nuts, fish, whole grains, plant-based oils and low-fat dairy products will help to keep a person in good health.

Habit Forming

No

Therapeutic Class

ANTIPSYCHOTICS

Melleril 100mg Tablet Substitute

Substitutes safety advice
  • Ornida 100mg Tablet

    by Others

    10.29per tablet
  • Sychozine 100mg Tablet

    by Others

    5.98per tablet
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Alcohol

Unsafe

Alcohol may worsen the condition and increase the risk of side effects while using Melleril 100mg Tablet.

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Pregnancy

Caution

Melleril 100mg Tablet is a category C pregnancy drug; using Melleril 100mg Tablet during pregnancy may affect your unborn baby. Please consult your doctor before taking Melleril 100mg Tablet if you are pregnant or planning to conceive.

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Breast Feeding

Caution

Melleril 100mg Tablet is known to pass through the breast milk. So, it is recommended not to be taken during breastfeeding. However, your doctor may prescribe it for you during breastfeeding if he/she feels that the benefits to you outweighs the risk.

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Driving

Unsafe

Melleril 100mg Tablet may cause drowsiness, and dizziness in some cases, especially in elderly patients. If you are affected, do not drive or operate dangerous machinery after taking Melleril 100mg Tablet.

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Liver

Caution

Melleril 100mg Tablet should be used with caution if you have liver disease. Your doctor may adjust the dose of this medicine based on your condition.

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Kidney

Caution

Melleril 100mg Tablet should be used with caution if you have kidney disease. Your doctor may adjust the dose of this medicine based on your condition.

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Children

Caution

Melleril 100mg Tablet is not recommended for children below 1 year of age. Children aged 1 and above can be given Melleril 100mg Tablet but take it only in dose and duration prescribed by your doctor.

Have a query?

FAQs

Melleril 100mg Tablet is used to treat schizophrenia or psychosis and bipolar disorder (manic depression).

Melleril 100mg Tablet contains ‘Thioridazine,’ an antipsychotic drug that blocks dopamine, a neurotransmitter in the brain responsible for developing schizophrenia and bipolar disorder symptoms. Melleril 100mg Tablet rebalances dopamine to improve thinking, mood, and behaviour.

You are not recommended to stop taking Melleril 100mg Tablet without consulting your doctor. It may cause withdrawal symptoms such as palpitations (the sensation that the heart skipped a beat or extra beat), anxiety, confusion, difficulty sleeping and tremors. Therefore, take Melleril 100mg Tablet for as long as your doctor has prescribed it, and if you experience any difficulty while taking Melleril 100mg Tablet, please consult your doctor so that the dose may be gradually reduced.

Melleril 100mg Tablet is not recommended for patients suffering from myasthenia gravis (severe muscle weakness) as it may worsen the condition. Therefore, inform your doctor if you have myasthenia gravis before taking Melleril 100mg Tablet.

Melleril 100mg Tablet may increase your body weight. So, while taking Melleril 100mg Tablet keep a check on your body weight. Also, monitor your blood sugar and cholesterol levels.

Melleril 100mg Tablet can decrease anxiety, irritability or agitation. However, you should consult a doctor before using Melleril 100mg Tablet for any condition.

No, Melleril 100mg Tablet should be taken with caution, especially in elderly patients with dementia, as Melleril 100mg Tablet is known to cause an increased death rate in such patients.

Melleril 100mg Tablet is known to cause changes in blood sugar levels. If you have diabetes and are taking Melleril 100mg Tablet, please regularly monitor your blood sugar level to avoid any unpleasant side effects of Melleril 100mg Tablet.

Other Info - ME85976

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