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  3. Mepan 40mg Tablet

Mepan 40mg Tablet, Pack of 1 Tablet
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Written By Lakshmithulasi Yarragunta ,
Reviewed By Praneetha Akunuri , M.Pharmacy

Mepan 40mg Tablet is used to treat gastroesophageal reflux disease (GERD), stomach ulcer, Zollinger Ellison syndrome (overproduction of acid due to pancreatic tumour), duodenal ulcer, gastric ulcer and Crohn's Disease-associated Ulcers. It contains Pantoprazole, which reduces the amount of acid your stomach makes. It prevents the release of stomach acid and relieves symptoms of food pipe lining inflammation (esophagitis), gastroesophageal reflux disease (GERD), or heartburn. It may cause common side effects like headache, diarrhoea, nausea, abdominal pain, vomiting, flatulence, dizziness, and arthralgia (joint pain). Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

PANTOPRAZOLE-40MG

Consume Type :

ORAL

Return Policy :

Not Returnable

About Mepan 40mg Tablet

Mepan 40mg Tablet belongs to the class of drugs known as Proton pump inhibitor, which reduces the amount of acid your stomach makes. It treats gastroesophageal reflux disease (GERD), stomach ulcers, Zollinger-Ellison syndrome (overproduction of acid due to a pancreatic tumour), duodenal ulcers, gastric ulcers, and Crohn’s disease-associated ulcers.

Mepan 40mg Tablet helps reduce stomach acid by blocking the action of an enzyme (H+/K+ ATPase, also known as the gastric proton pump), thus prevents the release of stomach acid and relieving symptoms of food pipe lining inflammation (esophagitis), gastroesophageal reflux disease (GERD), or heartburn.

Not everyone who is taking Mepan 40mg Tablet will get these side effects. Mepan 40mg Tablet may have common side effects, such as headache, diarrhoea, nausea, abdominal pain, vomiting, dizziness, and joint pain. These side effects are temporary and may resolve on their own over time. However, if these side effects persist, don't hesitate to contact your doctor.

Take Mepan 40mg Tablet as advised. Your physician will decide the dosage based on your medical condition. You should take Mepan 40mg Tablet 30 minutes before food. It is recommended not to exceed the recommended dose of Mepan 40mg Tablet. Do not chew, crush, or break the medicine.

Inform your physician if you are allergic to Mepan 40mg Tablet. Tell your doctor if you have stomach or intestinal cancer, liver problems, are allergic to Mepan 40mg Tablet or will have an endoscopy in the future. Prolonged intake of Mepan 40mg Tablet may cause a deficiency of Vitamin B12 and low levels of calcium, magnesium and Vitamin D, leading to osteoporosis. Mepan 40mg Tablet is not recommended for children below 5 years of age. Consult the doctor if you are pregnant or breastfeeding.

Uses of Mepan 40mg Tablet

Mepan 40mg Tablet is used to treat peptic ulcers, heartburn, and hyperacidity. The following are the specific applications of Mepan 40mg Tablet:
• Gastric reflux disease (GERD): Mepan 40mg Tablet is frequently used to treat GERD by decreasing the production of stomach acid, which lessens the symptoms of acid reflux and heartburn.
• Erosive Esophagitis: This medication efficiently promotes healing and symptom relief for this ailment, which is brought on by inflammation and damage to the esophagus as a result of acid reflux.
• Peptic Ulcers: By lowering stomach acid, Mepan 40mg Tablet can be used to treat peptic ulcers and promote the healing of the affected areas.
• Zollinger-Ellison Syndrome: This uncommon ailment results in an overabundance of stomach acid. Mepan 40mg Tablet considerably lowers acid secretion, which aids with symptom management.

Directions for Use

  • Mepan 40mg Tablet should be taken 30-60 minutes before a meal to enhance absorption and effectiveness.
  • It is usually taken once daily in the morning or as advised by your doctor. If prescribed twice daily, take the second dose before dinner.
  • Swallow Mepan 40mg Tablet as a whole with a glass of water.
  • Do not crush, chew, open, or break it.

Medicinal Benefits

  • Mepan 40mg Tablet is effective in healing erosive esophagitis (inflammation of the food pipe), heartburn, Zollinger-Ellison syndrome, duodenal ulcers, gastric ulcers, and Crohn’s disease-associated ulcers. 
  • Mepan 40mg Tablet works by irreversibly blocking the proton pump gate, which secretes stomach acid. It can be prescribed to all age groups, including special populations like the elderly, pregnant, lactating mothers, and patients with kidney and liver disease.
  • Mepan 40mg Tablet helps manage acidity-related conditions, promotes digestion, and provides relief from associated discomfort.

How Mepan 40mg Tablet Works

Mepan 40mg Tablet contains pantoprazole as an active ingredient. It helps reduce stomach acid by blocking the action of an enzyme (H+/K+ ATPase) that is located in the cells of the stomach wall and is responsible for releasing gastric acid, which can damage tissues in the food pipe, stomach, and duodenum. Mepan 40mg Tablet prevents the release of stomach acid and relieves symptoms of food pipe lining inflammation (esophagitis), gastroesophageal reflux disease (GERD), or heartburn.

Storage

Store in a cool and dry place away from sunlight
Side effects of Mepan 40mg Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Chest pain may last for a while and needs immediate medical attention as it is a significant health issue to be attended to.
  • Take rest and refrain from doing physical activity for a while, and restart after a few days.
  • Try applying an ice pack to the strained area for at least 20 minutes thrice a day. Ice pack thus helps reduce inflammation.
  • Sit upright and maintain proper posture if there is persistent chest pain. • Use extra pillows to elevate your position and prop your chest up while sleeping.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.

What if I have taken an overdose of Mepan 40mg Tablet

Do not take more than the prescribed dose of Mepan 40mg Tablet as it may cause an overdose. If you suspect you have taken an overdose, please consult a doctor immediately.

Drug Warnings

Avoid taking Mepan 40mg Tablet if you are allergic to Mepan 40mg Tablet or have any history of gastric cancer, liver disease, low magnesium levels, or low vitamin B1. Prolonged intake of Mepan 40mg Tablet may cause lupus erythematosus (an inflammatory condition in which the immune system attacks its own tissues), vitamin B12, and magnesium deficiency. Mepan 40mg Tablet may interact with blood thinners, antifungals, anti-HIV drugs, iron supplements, and anti-cancer medications. Please inform your doctor if you are taking any of these medications. Intake of Mepan 40mg Tablet may mask the symptoms of gastric cancer, so if you have any severe stomach pain or blood in stool, immediately consult the doctor.

It is advised to stop consuming alcohol and smoking, as it can cause serious side effects. This medicine is not recommended for use in children below 5 years of age. Although Mepan 40mg Tablet is safe for use during pregnancy or breastfeeding, inform your doctor if you are pregnant or breastfeeding before starting treatment with Mepan 40mg Tablet. Let your doctor know if you are taking any other medicines, including supplements and herbal products, to prevent any interactions.

Store Mepan 40mg Tablet at room temperature. You are advised not to chew, crush or break the medicine. Keep the medicine out of reach of children. Do not take more than the recommended dose of medicine, as it can cause undesirable effects. It is always important to check the expiry date of the medicine. Discard the medicine if it reaches the expiry date.

Drug-Drug Interactions

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PantoprazoleRilpivirine
Critical
PantoprazolePazopanib
Severe

Drug-Drug Interactions

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PantoprazoleRilpivirine
Critical
How does the drug interact with Mepan 40mg Tablet:
Co-administration of Rilpivirine is taken with Mepan 40mg Tablet, can decrease the absorption and blood levels of Rilpivirine and make the medication less effective.

How to manage the interaction:
Taking Mepan 40mg Tablet with Rilpivirine can lead to an interaction, please consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
PantoprazolePazopanib
Severe
How does the drug interact with Mepan 40mg Tablet:
Taking Mepan 40mg Tablet with Pazopanib may reduce the effectiveness of pazopanib.

How to manage the interaction:
If you are supposed to take Mepan 40mg Tablet and Pazopanib together, but can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
PantoprazoleNelfinavir
Severe
How does the drug interact with Mepan 40mg Tablet:
Taking Nelfinavir with Mepan 40mg Tablet may decrease the absorption and blood levels of Nelfinavir and reduce its effectiveness.

How to manage the interaction:
Taking Mepan 40mg Tablet with Nelfinavir together can possibly result in an interaction, but it can be taken if a doctor has advised it. A doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.
PantoprazoleGefitinib
Severe
How does the drug interact with Mepan 40mg Tablet:
Taking Gefitinib with Mepan 40mg Tablet reduces the acidity level in the stomach and may interfere with the absorption of Gefitinib and reduce its effectiveness.

How to manage the interaction:
Taking Mepan 40mg Tablet with Gefitinib together can possibly result in an interaction, it can be taken if your doctor has advised it. You are recommended to take gefitinib 12 hours before or 12 hours after Mepan 40mg Tablet to help minimize the impact of the interaction. Do not discontinue the medication without consulting a doctor.
PantoprazoleErlotinib
Severe
How does the drug interact with Mepan 40mg Tablet:
Taking Erlotinib with Mepan 40mg Tablet may interfere with the absorption of Erlotinib into the bloodstream, and reduce its effectiveness.

How to manage the interaction:
Taking Mepan 40mg Tablet with Erlotinib together can possibly result in an interaction, but it can be taken if a doctor has advised it. A doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.
PantoprazoleMethotrexate
Severe
How does the drug interact with Mepan 40mg Tablet:
Co-administration of Methotrexate with Mepan 40mg Tablet can increase the levels and side effects of Methotrexate.

How to manage the interaction:
Although there is a possible interaction between Mepan 40mg Tablet and methotrexate, you can take these medicines together if prescribed by a doctor. However, if you experience any symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, tiredness, weakness, or dizziness, consult a doctor. Do not stop using any medications without consulting a doctor.
PantoprazoleDacomitinib
Severe
How does the drug interact with Mepan 40mg Tablet:
Taking Mepan 40mg Tablet can make Dacomitinib less effective by reducing its absorption in the body.

How to manage the interaction:
Taking Mepan 40mg Tablet with Dacomitinib together can possibly result in an interaction, but it can be taken if a doctor has advised it. A doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.
PantoprazoleAtazanavir
Severe
How does the drug interact with Mepan 40mg Tablet:
Co-administration of Mepan 40mg Tablet reduces stomach acid, decreases the absorption and blood levels of Atazanavir, and reduces its effectiveness.

How to manage the interaction:
Taking Mepan 40mg Tablet with Atazanavir together can possibly result in an interaction, but it can be taken if a doctor has advised it. A doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.
PantoprazoleDasatinib
Severe
How does the drug interact with Mepan 40mg Tablet:
Taking Dasatinib with Mepan 40mg Tablet may decrease the blood levels of Dasatinib and reduce its effectiveness.

How to manage the interaction:
Taking Mepan 40mg Tablet with Dasatinib together can result in an interaction, but it can be taken if a doctor has advised it. In case of any unusual side effects, contact a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid consuming foods or drinks that trigger acid reflux or heartburn, such as onions, peppermint, chocolate, caffeinated beverages, citrus fruits or juices, tomatoes, high-fat foods, and spicy foods.
  • Before going to sleep, raise your bedhead so that your head and chest are higher than your feet. Do not use piles of pillows; one raised block is fine. This will prevent stomach acid from backing up into your food pipe.
  • Avoid taking alcohol and smoking cigarettes. Alcohol can raise the level of production of stomach acid, leading to heartburn and acid reflux. On the other hand, nicotine smoking damages the valve (sphincter), preventing the backflow of the stomach acid into the food pipe.
  • Include high-fibre-containing foods, such as berries, cherries, leafy green veggies (like kale and spinach), and black pepper in your meal. These foods are rich in antioxidants, calcium, and vitamin B12, which can help mitigate the long-term effects of the medicine. Fermented dairy products like miso, sauerkraut, and kimchi contain probiotics which help in the prevention of excess stomach acid production. Cranberry juice can be beneficial for peptic ulcers and H. pylori infection.
  • Avoid sitting for long periods, as it can increase stomach acid production. Try to take a 5-minute break every hour by going for a brisk walk or stretching.

Habit Forming

No

Therapeutic Class

ANTACIDS

Mepan 40mg Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Drinking alcohol with Mepan 40mg Tablet may cause dehydration and elevate the level of stomach acid thereby decreasing its efficiency. So try to avoid, limit alcohol or contact doctor before intake of Mepan 40mg Tablet.

bannner image

Pregnancy

Consult your doctor

Mepan 40mg Tablet is safe for use in pregnant women. However, please consult your physician before taking the medicine. Your doctor will weigh the benefits and potential risks before prescribing it.

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Breast Feeding

Consult your doctor

Mepan 40mg Tablet is safe for use in lactating mothers. However, please consult your physician before taking the medicine. Your doctor will weigh the benefits and potential risks before prescribing it.

bannner image

Driving

Caution

In some cases, Mepan 40mg Tablet may cause dizziness, sleepiness, or blur vision. If you observe these symptoms, do not drive or operate heavy machinery until you feel better.

bannner image

Liver

Caution

Mepan 40mg Tablet should be taken with caution if you have liver problems.

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Kidney

Consult your doctor

Patients with kidney disease should consult a doctor before taking Mepan 40mg Tablet.

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Children

Caution

Mepan 40mg Tablet is not be prescribed for children under 5 years of age. It is generally prescribed from 5-16 years of children for the treatment of gastroesophageal reflux disease (GERD).

Have a query?

FAQs

Mepan 40mg Tablet is used to treat Hyperacidity, Heartburn, and Peptic ulcer.

Mepan 40mg Tablet prevents the release of stomach acid and relieves symptoms of food pipe lining inflammation (esophagitis), gastroesophageal reflux disease (GERD), or heartburn.

No. Gas and acidity are two different common discomforts. Acidity is caused when the improper functioning of the valve (sphincter) is located at the junction of the stomach and the food pipe. As a result, stomach acid backs up and enters the upper part of the oesophagus, causing heartburn. On the other hand, gas is a byproduct of digestion, eliminating gases like carbon dioxide, hydrogen, nitrogen, and methane from the body.

Yes. Mepan 40mg Tablet can alter specific medical tests, such as neuroendocrine tumour (secretin stimulation test) and urine screening tests for tetrahydrocannabinol (THC). So, before undergoing such tests, contact your doctor.

Prolonged intake of Mepan 40mg Tablet may weaken your bone and lower your haemoglobin level. Your doctor may prescribe you Vitamin B12 for enhancing haemoglobin and calcium/vitamin D/magnesium supplements for bone health.

No. Mepan 40mg Tablet prevents the excessive production of stomach acid, which can cause acid reflux and heartburn. If blood is present in your stool or mucus, contact your doctor immediately.

Prolonged intake of Mepan 40mg Tablet may lead to atrophic gastritis (inflammation of stomach cells), Vitamin B12 deficiency and weakening of bones or osteoporosis (loss of calcium, magnesium and vitamin D). Your doctor may prescribe calcium, vitamin D or haemoglobin-enhancing medications to cope with long-term side effects.

No. Mepan 40mg Tablet is not prescribed for stomach cancer. Do not take Mepan 40mg Tablet until your doctor has prescribed it to you. Mepan 40mg Tablet is only indicated for the treatment of hyperacidity, acid reflux symptoms (GERD), heartburn and Zollinger-Ellison syndrome.

You should start to feel better in 2-3 days of starting Mepan 40mg Tablet. However, it might take up to 4 weeks for Mepan 40mg Tablet to work properly. Consult a doctor if you don't feel better or if your condition doesn't improve.

A single dose of Mepan 40mg Tablet may not be sufficient. To treat your condition properly, take Mepan 40mg Tablet in the dose and for the duration prescribed by your doctor.

Yes, it is safe to take Mepan 40mg Tablet if your doctor prescribes it. It is a well-tolerated medicine.

Mepan 40mg Tablet is usually prescribed for a short term. However, in some cases, it may be indicated in the long-term management of reflux oesophagitis. If you take Mepan 40mg Tablet on a long-term basis (longer than 1 year), your doctor will advise regular monitoring.

It is best to take Mepan 40mg Tablet 30 minutes to one hour before a meal.

Mepan 40mg Tablet should not be discontinued without a doctor’s consultation. To treat your condition effectively, take Mepan 40mg Tablet for as long as it has been prescribed. Talk to the doctor if you have any concerns.

Mepan 40mg Tablet may cause weight changes as a side effect. Consult the doctor if you notice any weight changes that bother you.

Avoid alcohol consumption as it might make your stomach produce more acid than usual. This can irritate the stomach lining and make your symptoms worse.

Antacids can be taken with Mepan 40mg Tablet if prescribed by the doctor. However, maintain a 2-hour gap between Mepan 40mg Tablet and antacid medicines.

Eat smaller and more frequent meals. Avoid foods that trigger acidity, such as fatty and fried foods, spicy foods, carbonated drinks, and alcohol. Include non-citrus fruits, vegetables, lean meat, oatmeal, whole-grain bread, and rice in your diet. Do not lie down immediately after eating, and avoid vigorous exercise for at least a couple of hours afterwards.

Yes, it is safe to take painkillers along with Mepan 40mg Tablet if advised by the doctor. To prevent stomach upset, painkillers can be taken with or just after a meal.

Mepan 40mg Tablet should be swallowed as a whole with water; do not crush, break or chew it. Mepan 40mg Tablet should be taken 30-60 minutes before meal.

Take the missed dose as soon as you remember, unless it is time for the scheduled dose. Do not take a double dose to make up for the forgotten dose. Take your next regular dose at the usual time.

In some people, Mepan 40mg Tablet may cause side effects such as headaches, diarrhoea, nausea, abdominal pain, vomiting, flatulence, dizziness, and arthralgia (joint pain). Most of these side effects are temporary and usually resolve over time. However, if any side effects persist or worsen, contact your doctor.

Country of origin

India
Other Info - ME78585

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Author Details

Praneetha AkunuriDoctor badge

Reviewed By

Praneetha Akunuri

M.Pharmacy

Last Updated

Jul 9, 2025 | 11:33 AM IST

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Reference

  1. https://www.drugs.com/tips/pantoprazole-patient-tips
  2. https://www.nhs.uk/medicines/pantoprazole/
  3. https://www.medicines.org.uk/emc/product/484/pil#gref
  4. https://www.drugs.com/pro/pantoprazole-granules.html#s-34068-7
  5. https://mms.mckesson.com/product/1002689/Pfizer-00008084402
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