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  3. Merofic-SB 1.5 gm Injection 1's

Merofic-SB 1.5 gm Injection 1's, Pack of 1
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
Merofic-SB 1.5 gm Injection is an anti-infective medicine used in treating bacterial infections. This medicine stops the growth of bacteria and thereby helps reduce various bacterial infections. It helps by inhibiting the bacterial cell synthesis and thereby helps fight infection-causing bacteria. This medicine is not effective for treating viral infections. Common side effects include swelling, pain, itching, nausea, vomiting, diarrhoea, headache, and rash.
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Composition :

MEROPENEM-1000MG + SULBACTAM-500MG

Manufacturer/Marketer :

Gufic Bioscience Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Merofic-SB 1.5 gm Injection

Merofic-SB 1.5 gm Injection belongs to the group of medications called anti-infectives used to treat bacterial infections. Bacterial infections are caused by the multiplication of harmful bacteria inside or on the body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. Symptoms of bacterial infection vary depending on the organ affected by bacteria.

Merofic-SB 1.5 gm Injection contains Meropenem and Sulbactam. Meropenem is a type of antibiotic. It works by preventing the formation of the bacterial protective covering, which is required for bacterial survival. Sulbactam is a beta-lactamase inhibitor that reduces resistance and improves Meropenem antibacterial activity.

Merofic-SB 1.5 gm Injection should only be administered under the supervision of a healthcare professional. The dose depends on the type of infection you have, where the infection is in the body, and how severe the infection is. Your doctor will decide on the dose that you need. The common side-effects of Merofic-SB 1.5 gm Injection may include injection site reactions that may occur, including swelling, pain, itching, nausea, vomiting, diarrhoea, headache, and rash. These side effects are usually mild and temporary. However, if any of these side effects persist or get worse, inform your doctor immediately.

To treat your condition effectually, continue using Merofic-SB 1.5 gm Injection for as long as your doctor has prescribed it. Do not use Merofic-SB 1.5 gm Injection without a doctor's advice if you had a skin reaction or irritation to any medicine. Consult your doctor before using Merofic-SB 1.5 gm Injection if you are pregnant or breastfeeding. Do not use Merofic-SB 1.5 gm Injection in more than prescribed doses or longer duration as it may cause adverse effects. Do not discontinue or abruptly stop the medication as it may lead to antibiotic resistance, a condition in which bacteria become resistant to antibiotics. Keep your doctor informed about your health condition and all the medicines you take before taking Merofic-SB 1.5 gm Injection to rule out any side effects. It is not known whether Merofic-SB 1.5 gm Injection can interact with alcohol or may affect your ability to drive. So, please discuss with your doctor the possible risks and benefits before taking this medicine.

Uses of Merofic-SB 1.5 gm Injection

Treatment of Bacterial infections

Directions for Use

• Follow your doctor's instructions on the dosage and timing of Merofic-SB 1.5 gm Injection. Typically, it is administered every 6 to 8 hours.• Merofic-SB 1.5 gm Injection will be administered by a doctor or nurse in a hospital setting.• Do not self-administer this medication.

Medicinal Benefits

Merofic-SB 1.5 gm Injection contains Meropenem and Sulbactam. Meropenem is an antibiotic that treats the infection by killing the bacteria. Sulbactam is a beta-lactamase (an enzyme produced by bacteria that can destroy antibiotics) inhibitor and prevents the destruction of Meropenem from the bacteria. Merofic-SB 1.5 gm Injection has broad-spectrum activity and is effective against both gram-positive and gram-negative bacteria. It is used to treat bacterial infections such as skin infections, gynecological infections, and intra-abdominal infections.

How Merofic-SB 1.5 gm Injection Works

Merofic-SB 1.5 gm Injection contains Meropenem and Sulbactam. Meropenem is a type of antibiotic. It works by preventing the formation of the bacterial protective covering, which is required for bacterial survival. Sulbactam is a beta-lactamase inhibitor that reduces resistance and improves Meropenem antibacterial activity.

Storage

Keep Merofic-SB 1.5 gm Injection out of reach and sight of children.

What if I have taken an overdose of Merofic-SB 1.5 gm Injection

Since Merofic-SB 1.5 gm Injection is administered by a healthcare professional, an overdose is unlikely to occur. However, seek medical attention if you experience any unusual symptoms.

Drug Warnings

It is not recommended to take Merofic-SB 1.5 gm Injection if you are allergic to other antibiotics or this medicine's contents. Merofic-SB 1.5 gm Injection is not recommended for people with infectious mononucleosis (viral infection with sore throat and fever) and colitis (intestine inflammation). Merofic-SB 1.5 gm Injection should be used with caution in patients with kidney impairment. Do not discontinue or abruptly stop the medication as it may lead to antibiotic resistance, a condition in which bacteria become resistant to antibiotics. Should use Merofic-SB 1.5 gm Injection with caution in children, pregnant women, breastfeeding mothers and older people. It is not known whether Merofic-SB 1.5 gm Injection can interact with alcohol or may affect your ability to drive. So, please discuss with your doctor the possible risks and benefits before taking this medicine.

Drug-Drug Interactions

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MeropenemTramadol
Severe
MeropenemIomeprol
Severe

Drug-Drug Interactions

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MeropenemTramadol
Severe
How does the drug interact with Merofic-SB 1.5 gm Injection:
Taking Tramadol with Merofic-SB 1.5 gm Injection together may cause higher levels of Merofic-SB 1.5 gm Injection in the blood.

How to manage the interaction:
Taking Merofic-SB 1.5 gm Injection with Tramadol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms such as confusion, hallucination, seizure, increased heart rate, blurred vision, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MeropenemIomeprol
Severe
How does the drug interact with Merofic-SB 1.5 gm Injection:
Co-administration of Iomeprol and Merofic-SB 1.5 gm Injection together can increase the risk of causing seizures.

How to manage the interaction:
Taking Merofic-SB 1.5 gm Injection with Iomeprol together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these signs - close monitoring, seizures, or head injury - contact a doctor right away." Do not stop using any medications without talking to a doctor.
MeropenemBCG vaccine
Severe
How does the drug interact with Merofic-SB 1.5 gm Injection:
When BCG vaccine is used with Merofic-SB 1.5 gm Injection, its effectiveness may be reduced.

How to manage the interaction:
Taking Merofic-SB 1.5 gm Injection with the BCG vaccine together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
MeropenemSodium Valproate
Severe
How does the drug interact with Merofic-SB 1.5 gm Injection:
Co-administration of Meropenam and Sodium valproate together can reduce the effect of Sodium valproate.

How to manage the interaction:
Co-administration of Meropenam and Sodium valproate can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any unusual symptoms, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
MeropenemDivalproex
Severe
How does the drug interact with Merofic-SB 1.5 gm Injection:
Co-administration of Divalproex and Merofic-SB 1.5 gm Injection can reduce the blood levels of Divalproex sodium.

How to manage the interaction:
Co-administration of Divalproex with Merofic-SB 1.5 gm Injection can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without a doctor's advice.
MeropenemMetrizamide
Severe
How does the drug interact with Merofic-SB 1.5 gm Injection:
Co-administration of Metrizamide and Merofic-SB 1.5 gm Injection together can increase the risk of seizures.

How to manage the interaction:
Taking Merofic-SB 1.5 gm Injection with Metrizamide together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these signs - being closely monitored by your doctor, having seizures, or having a condition or head injury - contact a doctor right away. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Probiotics should be taken after taking an entire course of Merofic-SB 1.5 gm Injection to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut, kombucha, and kimchi can help restore the intestine's good bacteria.
  • Include more fibre enriched food in your diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fibre rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains like whole-grain bread, brown rice should be included in your diet.
  • Avoid alcoholic beverages with Merofic-SB 1.5 gm Injection as it can make you dehydrated and may affect your sleep. This can make it harder for your body to aid the Merofic-SB 1.5 gm Injection in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTI- INFECTIVES

Merofic-SB 1.5 gm Injection Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Alcohol may increase the side effects of Merofic-SB 1.5 gm Injection. Hence, it is advised to limit the intake of alcohol while using Merofic-SB 1.5 gm Injection.

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Pregnancy

Caution

Merofic-SB 1.5 gm Injection should be used in pregnant women only if clinically needed when the benefits outweigh the risks. Your doctor will weigh the benefits and any potential risks before prescribing Merofic-SB 1.5 gm Injection.

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Breast Feeding

Caution

Consult your doctor as there is no substantial research yet on the use of Merofic-SB 1.5 gm Injection in breastfeeding/nursing mothers.

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Driving

Caution

It is not known whether Merofic-SB 1.5 gm Injection alters the ability to drive. Do not drive or operate machinery if you experience any symptoms that affect your ability to concentrate and react. Seek medical attention if the symptoms persist longer.

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Liver

Caution

Merofic-SB 1.5 gm Injection should be used with caution in patients with liver diseases as it may affect liver function. The dose may have to be adjusted by your doctor. Please consult the doctor.

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Kidney

Caution

Merofic-SB 1.5 gm Injection should be used with caution in patients with kidney diseases. Your doctor will weigh the benefits and any potential risks before prescribing Merofic-SB 1.5 gm Injection.

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Children

Caution

Merofic-SB 1.5 gm Injection should be used in children only if clinically needed. The doctor may have to adjust the dose based on age, body weight and medical history.

Have a query?

FAQs

Merofic-SB 1.5 gm Injection belongs to the group of medications called anti-infectives used to treat bacterial infections.

Merofic-SB 1.5 gm Injection is used to treat bacterial infections. It contains Meropenem and Sulbactam. Meropenem reduces the infection by inhibiting bacterial growth. It disrupts the cell wall formation (outer layer), which is essential for bacteria's survival. Sulbactam inhibits the action of beta-lactamase, an enzyme produced by the bacteria to destroy antibiotics (Meropenem).

Take the missed dose as soon as possible. However, skip the missed dose and return to your regular dosing schedule if it is time for the next dose. Do not take a double dose to make up for the dose that you missed.

Do not stop using Merofic-SB 1.5 gm Injection even if you feel better. It should be strictly used as advised by your doctor to avoid the recurrence of symptoms and to worsening of the disease.

Merofic-SB 1.5 gm Injection should not be given to the people with infectious mononucleosis (viral infection with sore throat and fever) and colitis (inflammation of the intestine) as Merofic-SB 1.5 gm Injection worsen these conditions.

Country of origin

India

Manufacturer/Marketer address

37,1St Floor, Kamala Bhavan Ii, Swami Nityanand Road, Andheri (East), Mumbai - 400 069. (India)
Other Info - MER0506

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Veda MaddalaDoctor badge

Reviewed By

Veda Maddala

M Pharmacy

Last Updated

Jul 18, 2025 | 6:55 AM IST

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Reference

  1. https://pubmed.ncbi.nlm.nih.gov/18707240/
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/050706s032s034lbl.pdf
  3. https://www.medicines.org.uk/emc/files/pil.9074.pdf

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