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Metaglez Forte Tablet is used to treat type 2 diabetes mellitus. It helps maintain stable blood sugar levels and lowers the risk of diabetes-related complications when used along with a healthy diet and regular exercise.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Aristo Pharmaceuticals Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Metaglez Forte Tablet

Metaglez Forte Tablet belongs to the class of anti-diabetic drugs. It is used in the treatment of type 2 diabetes mellitus. Diabetes mellitus is a metabolic disease that causes high blood sugar levels.

Metaglez Forte Tablet contains Glipizide and Metformin. Glipizide promotes insulin secretion from the beta cells of the pancreas and reduces the glucose output from the liver. Metformin reduces serum glucose levels without increasing insulin secretion.

Take Metaglez Forte Tablet as prescribed by your doctor. The common side effects of Metaglez Forte Tablet include low blood sugar, nausea, diarrhoea, indigestion, headache, dizziness and blurred vision. Although not everyone experiences these side effects, if they occur, seek medical attention.

Before starting Metaglez Forte Tablet , let your doctor know if you have any medical history of low haemoglobin levels, seizures (fits), heart, kidney, and liver diseases. Consult your doctor if you are pregnant or breastfeeding.

Uses of Metaglez Forte Tablet

Metaglez Forte Tablet is used in the treatment of Type 2 Diabetes mellitus. The detailed uses of Metaglez Forte Tablet are as follows:

  • Management of Type 2 Diabetes: Metaglez Forte Tablet is primarily used to help control blood sugar levels in individuals with type 2 diabetes mellitus.
  • Weight Management: In some cases, Metaglez Forte Tablet may assist with weight management in diabetic patients by helping to regulate blood sugar levels and reduce hunger cravings.

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Directions for Use

  • Take Metaglez Forte Tablet with meals or as advised by your doctor.
  • Follow your doctor’s recommendation regarding the dosage and duration.
  • Swallow Metaglez Forte Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it.

Key Benefits

  • Metaglez Forte Tablet helps effectively control blood sugar levels in patients with type 2 diabetes mellitus.
  • It improves insulin sensitivity in muscle, fat, and liver cells, helping to better glucose utilisation.
  • Metaglez Forte Tablet helps maintain stable blood glucose levels throughout the day.
  • It helps reduce the risk of long-term diabetes complications such as nerve damage, eye problems, and kidney disease.
  • Metaglez Forte Tablet supports overall metabolic health when used along with a proper diet and regular exercise.

How Metaglez Forte Tablet Works

Metaglez Forte Tablet is composed of two medicines, namely Glipizide and Metformin. • Glipizide belongs to the class of sulfonylureas. It promotes insulin secretion from the beta cells of the pancreas and reduces the glucose output from the liver. • Metformin belongs to the class of biguanides. It exhibits a non-pancreatic effect to reduce serum glucose levels without increasing insulin secretion. It is also known as an insulin sensitiser as it increases the effects of insulin.

Storage

Store in a cool and dry place away from sunlight
Side effects of Metaglez Forte Tablet
  • If you experience low blood sugar levels, inform your doctor. They will assess the severity and make recommendations for the next actions.
  • Your doctor will assess your symptoms, blood sugar levels, and overall health before recommending the best course of action, which may include treatment, lifestyle modifications, or prescription adjustments.
  • Follow your doctor's instructions carefully to manage the episode and adjust your treatment plan.
  • Make medication adjustments as recommended by your doctor to prevent future episodes.
  • Implement diet and lifestyle modifications as your doctor advises to manage low blood sugar levels.
  • Monitor your blood sugar levels closely for patterns and changes.
  • Track your progress by recording your blood sugar levels, food intake, and physical activity.
  • Seek further guidance from your doctor if symptoms persist or worsen so that your treatment plan can be revised.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.

What if I have taken an overdose of Metaglez Forte Tablet

An overdose of Metaglez Forte Tablet may result in lactic acidosis or severe low blood sugar. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

  • Do not take Metaglez Forte Tablet if you are allergic to any of its components.
  • Consult your doctor if you are pregnant or breastfeeding.
  • Inform your doctor if you have liver, kidney or heart problems.
  • Avoid alcohol consumption as it may increase the risk of low blood glucose.
  • Metaglez Forte Tablet has an increased risk of lactic acidosis (lactic acidosis is caused by a buildup of lactic acid in the blood). Seek medical attention if you experience weakness, unusual muscle pain, trouble breathing, unusual or unexpected stomach discomfort, feeling cold, feeling dizzy or lightheaded, or suddenly developing a slow or irregular heartbeat.

Drug-Drug Interactions

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MetforminIotroxic acid
Critical
MetforminIoglycamic acid
Critical

Drug-Drug Interactions

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MetforminIotroxic acid
Critical
How does the drug interact with Metaglez Forte Tablet:
Co-administration of Iotroxic acid with Metaglez Forte Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Metaglez Forte Tablet with Iotroxic acid is not recommended, please consult your doctor before taking it.
MetforminIoglycamic acid
Critical
How does the drug interact with Metaglez Forte Tablet:
Co-administration of Ioglycamic acid with Metaglez Forte Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Metaglez Forte Tablet with Ioglycamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIomeprol
Critical
How does the drug interact with Metaglez Forte Tablet:
Co-administration of Iomeprol with Metaglez Forte Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Metaglez Forte Tablet with Iomeprol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIopamidol
Critical
How does the drug interact with Metaglez Forte Tablet:
Co-administration of Iopamidol with Metaglez Forte Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Metaglez Forte Tablet with Iopamidol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIocarmic acid
Critical
How does the drug interact with Metaglez Forte Tablet:
Co-administration of Metaglez Forte Tablet and Iocarmic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Metaglez Forte Tablet with Iocarmic acid is generally avoided as it can result in an interaction. please consult your doctor before taking it.
MetforminIobitridol
Critical
How does the drug interact with Metaglez Forte Tablet:
Co-administration of Metaglez Forte Tablet and Iobitridol can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Metaglez Forte Tablet with Iobitridol is generally avoided as it can result in an interaction. Please consult your doctor before taking it.
MetforminIocetamic acid
Critical
How does the drug interact with Metaglez Forte Tablet:
Co-administration of Metaglez Forte Tablet and Iocetamic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Metaglez Forte Tablet with Iocetamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIodamide
Critical
How does the drug interact with Metaglez Forte Tablet:
Co-administration of Metaglez Forte Tablet and Iodamide can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Metaglez Forte Tablet with Iodamide is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIodixanol
Critical
How does the drug interact with Metaglez Forte Tablet:
Co-administration of Iodixanol with Metaglez Forte Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Metaglez Forte Tablet with Iodixanol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIofendylate
Critical
How does the drug interact with Metaglez Forte Tablet:
Co-administration of Iofendylate with Metaglez Forte Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Metaglez Forte Tablet with Iofendylate is generally avoided as it can result in an interaction, please consult your doctor before taking it.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Healthy Eating Habits:

  • Follow a balanced diet that includes whole grains, vegetables, lean proteins, and healthy fats.
  • Limit intake of sugary foods, sweets, and sweetened beverages to maintain blood glucose control.
  • Eat meals at regular intervals to prevent sudden fluctuations in blood sugar levels.
  • Choose foods with a low glycaemic index whenever possible.

Physical Activity and Weight Management:

  • Engage in regular physical activity such as walking, yoga, or light exercise.
  • Maintain a healthy body weight to improve insulin sensitivity.

Lifestyle and Daily Care:

  • Maintain a regular sleep schedule and manage stress effectively.
  • Avoid smoking and limit alcohol consumption.

Habit Forming

No

Therapeutic Class

[ANTIDIABETICS]

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Alcohol

Caution

You are recommended to avoid consumption of alcohol with Metaglez Forte Tablet as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body).

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Pregnancy

Caution

Metaglez Forte Tablet may affect the fetus during pregnancy. Please consult your doctor before starting Metaglez Forte Tablet .

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Breast Feeding

Caution

There is no sufficient data on how Metaglez Forte Tablet affects breastfeeding. It is safe to seek medical advice before you start Metaglez Forte Tablet if you are lactating.

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Driving

Caution

Your driving may be affected if your blood sugar levels are too high or too low. Do not drive or operate machinery if you may experience dizziness or drowsiness.

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Liver

Caution

Let your doctor know if you have any history of liver diseases or hepatic impairment when you are prescribed Metaglez Forte Tablet .

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases when you are prescribed Metaglez Forte Tablet .

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Children

Caution

Please seek advice from a doctor before giving Metaglez Forte Tablet to a child.

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Heart

Consult your doctor

Metaglez Forte Tablet should be used with caution if you have any cardiac problems. This medicine is contraindicated in patients with severe heart failure.

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Geriatrics

Caution

Caution should be exercised in geriatric patients while taking Metaglez Forte Tablet .

FAQs

Metaglez Forte Tablet is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

Metaglez Forte Tablet promotes insulin secretion from the beta cells of the pancreas and reduces the glucose output from the liver. It works by reducing the sugar production by cells in the liver and delaying sugar absorption from the intestines.

You are not recommended to stop taking Metaglez Forte Tablet on your own, as discontinuing Metaglez Forte Tablet suddenly may cause recurring symptoms or worsen the condition. However, if you experience any difficulty while taking Metaglez Forte Tablet , please consult your doctor so that alternative medicine may be prescribed.

In type 1 diabetes, the body does not produce insulin as the islet cells (insulin-producing cells) in the pancreas are destroyed completely. In type 2 diabetes, though islet cells are working, the body does not respond to insulin as the body becomes resistant to insulin.

Metaglez Forte Tablet may increase the risk of low blood sugar levels, especially with alcohol intake, exercise more than usual, and delay or miss snacks or meals. However, if you experience any signs of low blood pressure, such as dizziness, nausea, light-headedness, dehydration or fainting, please consult a doctor.

Take Metaglez Forte Tablet as advised by your doctor. Swallow it as a whole with a glass of water. Do not break, crush or chew it.

Metaglez Forte Tablet should be taken preferably with a meal, as it lowers the blood sugar levels and causes gastrointestinal side effects. Follow your doctor’s instructions.

Metaglez Forte Tablet contains two anti-diabetic drugs, namely Glipizide and Metformin, as its active ingredients.

Metaglez Forte Tablet may cause side effects such as low blood sugar, nausea, indigestion, headache, diarrhoea, stomach pain, or blurred vision. If these side effects persist or worsen, please consult your doctor.

Yes, the use of Metaglez Forte Tablet can cause hypoglycemia (low blood sugar). Symptoms of hypoglycemia include hunger, dizziness, sweating, headache, nausea, irritability, fast heart rate and feeling anxious or shaky. It occurs more frequently if you miss or delay meals, over-exercise, drink alcohol, or take other antidiabetic medication along with it. Therefore, it is important to regularly monitor blood sugar levels. Always carry some fruit juice, honey or glucose tablets with you.

Yes, the use of Metaglez Forte Tablet can cause lactic acidosis. It is a medical emergency which occurs due to increased levels of lactic acid in the blood. It is also known as MALA (Metformin associated lactic acidosis). It is a rare side effect associated with the metformin and thus, it is contraindicated in patients with underlying kidney disease, elderly patients or who consume large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, feeling of cold in arms and legs, dizziness, tiredness, difficulty in breathing, stomach pain, nausea, vomiting or slow heart rate. If you experience these symptoms, stop taking Metaglez Forte Tablet and consult your doctor immediately.

Yes, long term use of Metaglez Forte Tablet can cause Vitamin B12 deficiency. It interferes with absorption of Vitamin B12 in the stomach. If untreated, it may cause nerve problems and anemia and the patient may feel numbness and tingling sensation in the hands and feet, urinary problems, weakness, change in mental status and difficulty in maintaining balance (ataxia). To prevent such problems, some researchers recommend an intake of Vitamin B12 from external sources at least once a year.

Metaglez Forte Tablet is contraindicated in patients with known allergy to any of its components or excipients. Also, it should be avoided in patients with moderate to severe kidney disease and in patients with underlying metabolic acidosis including diabetic ketoacidosis.

No, you are recommended to avoid alcohol consumption while taking Metaglez Forte Tablet , as it may lower blood sugar levels (hypoglycemia) and increase the risk of lactic acidosis.

Store Metaglez Forte Tablet at room temperature protected from moisture. Keep it out of reach of children.

It is recommended to take a doctor’s advice if you are pregnant or planning pregnancy before taking Metaglez Forte Tablet .

Metaglez Forte Tablet overdose can result in serious complications such as hypoglycaemia (low blood sugar) or lactic acidosis. Hence, if you suspect an overdose, seek medical attention immediately.

No, do not split or crush Metaglez Forte Tablet . Swallow it as whole with a glass of water.

Country of origin

India

Manufacturer/Marketer address

Mercantile Chamber, 3rd Floor, 12, J.N. Heredia Marg, Ballard Estate, Mumbai – 400 001, India.
Other Info - MET0082

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