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  3. Methergin Tablet 10's

Methergin Tablet 10's, Pack of 10 TABLETS
Methergin Tablet 10's, Pack of 10 TABLETS
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Methergin Tablet is used to prevent and control postpartum haemorrhage. This medicine contains methylergometrine, which increases the uterus's smooth muscle contractions and thereby controls bleeding after delivery. Some of the side effects include seizures and/or headache, nausea, and vomiting.
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Composition :

METHYLERGOMETRINE-0.125MG

Manufacturer/Marketer :

Novartis India Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Methergin Tablet

Methergin Tablet is used to prevent and control postpartum haemorrhage. It is used after delivery for the routine management of uterine atony, subinvolution of the uterus, and haemorrhage.

Methergin Tablet contains Methylergometrine, which works by increasing the smooth muscle contractions of the uterus. This helps compress the blood vessels and controls bleeding after delivery.

Take Methergin Tablet exactly as prescribed by the doctor. In some cases, Methergin Tablet may cause high blood pressure associated with seizures and/or headache, nausea, and vomiting. If the side effects persist or worsen, consult your doctor.

Do not take Methergin Tablet if you are pregnant. Consult your doctor if you are breastfeeding. Methergin Tablet is not recommended for children as safety and effectiveness have not been established. Keep your doctor informed about your health condition and medications to rule out any interactions/side effects.

Uses of Methergin Tablet

Treatment of Postpartum haemorrhage

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Directions for Use

• Methergin Tablet can be taken with or without food.• Your healthcare provider will decide the correct dosage and frequency based on your condition.• Take it exactly as prescribed, usually with a full glass of water.• Do not crush, chew, or break the tablet. Swallow it whole as directed.• Do not change the dose or stop taking the medication without first consulting your doctor.

Medicinal Benefits

Methergin Tablet is indicated in the prevention and control of postpartum haemorrhage. It is used following delivery of the placenta for the routine management of uterine atony (soft and weak uterus after childbirth), subinvolution of the uterus, and haemorrhage. Methergin Tablet contains Methylergometrine, a semi-synthetic ergot alkaloid which works by increasing the smooth muscle contractions of the uterus. This helps compress the blood vessels and controls bleeding after delivery.

How Methergin Tablet Works

Methergin Tablet contains Methylergometrine, which works by increasing the smooth muscle contractions of the uterus. This helps compress the blood vessels and controls bleeding after delivery.

Storage

• Store in a cool and dry place away from sunlight.
• Keep Methergin Tablet out of reach and sight of children.
• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Methergin Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

What if I have taken an overdose of Methergin Tablet

Avoid taking more than the prescribed dose of Methergin Tablet as it can cause serious side effects. Overdose of Methergin Tablet include severe headache, severe dizziness, seizures, slow/shallow breathing. Seek immediate medical attention if you observe any of these side effects.

Drug Warnings

Do not take Methergin Tablet if you are allergic to any of its components, if you have high blood pressure, toxaemia (a complication of pregnancy characterised by high blood pressure), or if you are pregnant. Inform your doctor if you have coronary artery disease, sepsis, vascular disease, or liver or kidney impairment. Consult your doctor if you are breastfeeding. The safety and effectiveness of Methergin Tablet in children have not been established. Let your doctor know if you are taking prescription/non-prescription medicines, including herbal products and supplements.

Drug-Drug Interactions

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MethylergometrineGlyceryl trinitrate
Critical
MethylergometrineKetoconazole
Critical

Drug-Drug Interactions

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MethylergometrineGlyceryl trinitrate
Critical
How does the drug interact with Methergin Tablet:
Coadministration of Methergin Tablet with Glyceryl trinitrate can increase the levels and side effects of Methergin Tablet.

How to manage the interaction:
Taking Methergin Tablet with Glyceryl trinitrate is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, headache, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor. Do not discontinue any medications without first consulting your doctor.
MethylergometrineKetoconazole
Critical
How does the drug interact with Methergin Tablet:
Using Ketoconazole with Methergin Tablet can increase the concentration of Methergin Tablet, which may lead to side effects.

How to manage the interaction:
Taking Ketoconazole with Methergin Tablet is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. Do not discontinue any medication without consulting a doctor.
MethylergometrineClarithromycin
Critical
How does the drug interact with Methergin Tablet:
When Methergin Tablet is taken with Clarithromycin, the amount of Methergin Tablet in the blood can go up. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Clarithromycin with Methergin Tablet is generally avoided as it can lead to an interaction, it can be taken only when advised by a doctor. Do not stop using any medications without a doctor's advice.
MethylergometrineRitonavir
Critical
How does the drug interact with Methergin Tablet:
Taking Methergin Tablet with Ritonavir can significantly increase the blood levels and effects of Methergin Tablet.

How to manage the interaction:
Taking Methergin Tablet with Ritonavir is not recommended, but can be taken together if prescribed by a doctor. In case you experience any side effects like severe abdominal discomfort, nausea, vomiting, tingling or numbness, weakness or pain in the muscles, pale skin, blue or purple discoloration on fingers or toes, tightness or pain in the chest, irregular heartbeat, intense headache, breathing difficulties, confusion, or slurred speech, consult a doctor. Do not discontinue any medications without consulting a doctor.
MethylergometrineItraconazole
Critical
How does the drug interact with Methergin Tablet:
Co-administration of Methergin Tablet and Itraconazole may increase the blood levels of Methergin Tablet.

How to manage the interaction:
Methergin Tablet and itraconazole may interact, but if prescribed by a doctor, they can be used together. Do not discontinue any medications without first consulting your doctor.
MethylergometrineSumatriptan
Critical
How does the drug interact with Methergin Tablet:
Coadministration of Sumatriptan with Methergin Tablet can reduce the blood flow and increase the risk of high blood pressure or heart-related problems.

How to manage the interaction:
Taking Sumatriptan with Methergin Tablet together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
MethylergometrineVoriconazole
Critical
How does the drug interact with Methergin Tablet:
Coadministration of Methergin Tablet with Voriconazole may increase the blood level of Methergin Tablet.

How to manage the interaction:
Although Methergin Tablet with Voriconazole can cause an interaction, they can be taken if prescribed by a doctor. Do not discontinue any medication without consulting a doctor.
MethylergometrineEphedrine
Severe
How does the drug interact with Methergin Tablet:
Taking Ephedrine with Methergin Tablet may lead to an increase in the risk of high blood pressure.

How to manage the interaction:
Although taking Ephedrine with Methergin Tablet may lead to an interaction, it can be taken if prescribed by the doctor. It is advised to maintain your blood pressure. Do not discontinue any medications without a doctor's advice.
MethylergometrinePhenylephrine
Severe
How does the drug interact with Methergin Tablet:
Taking Phenylephrine with Methergin Tablet can led to side effects like increased blood pressure.

How to manage the interaction:
Taking Phenylephrine with Methergin Tablet can lead to an interaction but can be taken if prescribed by the doctor. It is advised to monitor your blood pressure regularly. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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METHYLERGOMETRINE-0.125MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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METHYLERGOMETRINE-0.125MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consumption of Methergin Tablet with Grapefruit and Grapefruit may lead to an increase in the effectiveness of Methergin Tablet. Avoid or limit grapefruit and grapefruit juice consumption with Methergin Tablet. This can increase the risk or severity of side effects.

Diet & Lifestyle Advise

  • Include high-fibre foods such as fruits and whole grains.
  • Drink plenty of fluids such as water, fruit juices, and milk.
  • Limit processed/packaged foods, high salt/sugary foods and saturated fats.
  • Get plenty of rest.
  • Eat healthy meals and exercise appropriately.

Habit Forming

No

Therapeutic Class

MISCELLANEOUS

Methergin Tablet Substitute

Substitutes safety advice
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Alcohol

Caution

It is not known if alcohol affects Methergin Tablet . Please consult your doctor.

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Pregnancy

Unsafe

Methergin Tablet is not recommended for use during pregnancy.

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Breast Feeding

Caution

Methergin Tablet passes into breastmilk. Avoid breastfeeding during treatment with Methergin Tablet and for 12 hours after the last dose. Please consult your doctor if you have any concerns.

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Driving

Caution

It is not known if Methergin Tablet affects your ability to drive.

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Liver

Caution

Caution should be exercised while using Methergin Tablet in patients with liver impairment. Please consult your doctor if you have liver problems or any concerns regarding this.

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Kidney

Caution

Caution should be exercised while using Methergin Tablet in patients with kidney impairment. Please consult your doctor if you have kidney problems or any concerns regarding this.

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Children

Unsafe

Methergin Tablet is not recommended for children as safety and effectiveness have not been established.

FAQs

Methergin Tablet is used to prevent and control postpartum haemorrhage. It is used after delivery for the routine management of uterine atony, subinvolution of the uterus, and haemorrhage.

Methergin Tablet works by increasing the smooth muscle contractions of the uterus. This helps compress the blood vessels and controls bleeding after delivery.

Methergin Tablet is not recommended for use in people with high blood pressure. Consult your doctor if you have hypertension.

Methergin Tablet may cause nausea or vomiting as a side effect. It is not necessary for everyone taking Methergin Tablet to experience this side effect. However, if the condition persists or worsens, consult your doctor.

Methergin Tablet may be indicated in the management of uterine atony. Uterine atony refers to a weak and soft uterus after childbirth.

Yes, Methergin Tablet may cause decreased milk production if taken by lactating mothers after childbirth. It is recommended to avoid breastfeeding while taking Methergin Tablet for at least 12 hours after your last dose. Consult the doctor if you have any concerns.

Methergin Tablet should not be used to stop uterine bleeding after child birth if the patient has high blood pressure as it may worsen hypertension. Consult the doctor if you have any concerns.

No, Methergin Tablet should not be used to stop menstrual bleeding as it is used to manage and prevent excessive bleeding after childbirth (postpartum haemorrhage).

Methergin Tablet should be taken with or without food as advised by the doctor based on your medical condition.

You should not take Methergin Tablet if you are allergic to any of its ingredients. It should not be taken by individuals with high blood pressure (hypertension), or toxaemia (an abnormal condition associated with the presence of toxic substances in the bloodstream) during pregnancy.

No, breastfeeding should be avoided during treatment with Methergin Tablet and for at least 12 hours after the final dose. Consult the doctor if you have any concerns.

Yes, Methergin Tablet may cause an increase in blood pressure as a common side effect. Consult the doctor before taking Methergin Tablet if you have high blood pressure.

Patients with heart disease may have an increased risk of myocardial ischemia and infarction due to methylergonovine-induced vasospasm. Consult the doctor if you have any heart problems.

The side effects of Methergin Tablet include nausea, vomiting, headache, and hypertension (increased blood pressure) associated with seizures. Consult the doctor if any of these symptoms persist or worsen.

Country of origin

India

Manufacturer/Marketer address

Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India
Other Info - MET0067

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 9:23 AM IST

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Reference

  1. https://www.drugs.com/pro/methylergonovine-maleate-tablets.html
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/006035s075lbl.pdf

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