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Composition :
METHOTREXATE-20MG
Manufacturer/Marketer :
Azista Industries Pvt Ltd
Consume Type :
PARENTERAL
Return Policy :
Not Returnable
Expires on or after :
Drug-Drug Interactions
MethotrexateEtretinate
Critical
Severe
Drug-Drug Interactions
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MethotrexateEtretinate
Critical
How does the drug interact with Methorapfs 20 Injection 0.4 ml:
Co-administration of Etretinate with Methorapfs 20 Injection 0.4 ml may increase the risk or severity of liver problems.
How to manage the interaction:
Taking Etretinate with Methorapfs 20 Injection 0.4 ml is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
Co-administration of Etretinate with Methorapfs 20 Injection 0.4 ml may increase the risk or severity of liver problems.
How to manage the interaction:
Taking Etretinate with Methorapfs 20 Injection 0.4 ml is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Methorapfs 20 Injection 0.4 ml:
Coadministration of omeprazole with Methorapfs 20 Injection 0.4 ml may increase the levels and side effects of omeprazole.
How to manage the interaction:
Although there is a possible interaction between omeprazole and Methorapfs 20 Injection 0.4 ml, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without consulting to a doctor.
Coadministration of omeprazole with Methorapfs 20 Injection 0.4 ml may increase the levels and side effects of omeprazole.
How to manage the interaction:
Although there is a possible interaction between omeprazole and Methorapfs 20 Injection 0.4 ml, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without consulting to a doctor.
Severe
How does the drug interact with Methorapfs 20 Injection 0.4 ml:
Using thalidomide together with Methorapfs 20 Injection 0.4 ml can increase the risk of developing blood clots.
How to manage the interaction:
Although there is a possible interaction between thalidoamide and Methorapfs 20 Injection 0.4 ml, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as chest pain, difficulty breathing, coughing up blood, sudden loss of vision, and/or pain, redness or swelling in an arm or leg, consult your doctor. Do not stop using any medications without consulting to a doctor.
Using thalidomide together with Methorapfs 20 Injection 0.4 ml can increase the risk of developing blood clots.
How to manage the interaction:
Although there is a possible interaction between thalidoamide and Methorapfs 20 Injection 0.4 ml, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as chest pain, difficulty breathing, coughing up blood, sudden loss of vision, and/or pain, redness or swelling in an arm or leg, consult your doctor. Do not stop using any medications without consulting to a doctor.
Severe
How does the drug interact with Methorapfs 20 Injection 0.4 ml:
Coadministration of Methorapfs 20 Injection 0.4 ml with tofacitinib can increase the risk of developing serious infections.
How to manage the interaction:
Although there is a possible interaction between tofacitinib and Methorapfs 20 Injection 0.4 ml, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin and pain or burning during urination, consult a doctor. Do not stop using any medications without consulting to a doctor.
Coadministration of Methorapfs 20 Injection 0.4 ml with tofacitinib can increase the risk of developing serious infections.
How to manage the interaction:
Although there is a possible interaction between tofacitinib and Methorapfs 20 Injection 0.4 ml, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin and pain or burning during urination, consult a doctor. Do not stop using any medications without consulting to a doctor.
Severe
How does the drug interact with Methorapfs 20 Injection 0.4 ml:
Coadministration of Everolimus with Methorapfs 20 Injection 0.4 ml can increase the risk or severity of kidney disorders.
How to manage the interaction:
Taking Everolimus with Methorapfs 20 Injection 0.4 ml together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not stop using any medications without talking to a doctor.
Coadministration of Everolimus with Methorapfs 20 Injection 0.4 ml can increase the risk or severity of kidney disorders.
How to manage the interaction:
Taking Everolimus with Methorapfs 20 Injection 0.4 ml together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Methorapfs 20 Injection 0.4 ml:
Coadministration of leflunomide with Methorapfs 20 Injection 0.4 ml may increase the risk or severity of liver problems.
How to manage the interaction:
Although there is an interaction between leflunomide and Methorapfs 20 Injection 0.4 ml, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Coadministration of leflunomide with Methorapfs 20 Injection 0.4 ml may increase the risk or severity of liver problems.
How to manage the interaction:
Although there is an interaction between leflunomide and Methorapfs 20 Injection 0.4 ml, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Methorapfs 20 Injection 0.4 ml:
Coadministration of trimethoprim with Methorapfs 20 Injection 0.4 ml can increase the risk or severity of blood disorders.
How to manage the interaction:
Although there is a possible interaction between trimethoprim and Methorapfs 20 Injection 0.4 ml, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as pale skin, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not stop using any medications without consulting to a doctor.
Coadministration of trimethoprim with Methorapfs 20 Injection 0.4 ml can increase the risk or severity of blood disorders.
How to manage the interaction:
Although there is a possible interaction between trimethoprim and Methorapfs 20 Injection 0.4 ml, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as pale skin, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not stop using any medications without consulting to a doctor.
Severe
How does the drug interact with Methorapfs 20 Injection 0.4 ml:
Co-administration of Methorapfs 20 Injection 0.4 ml with pantoprazole can increase the levels and side effects of Methorapfs 20 Injection 0.4 ml.
How to manage the interaction:
Although there is a possible interaction between pantoprazole and Methorapfs 20 Injection 0.4 ml, you can take these medicines together if prescribed by a doctor. However, if you experience any symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, tiredness, weakness, or dizziness, consult a doctor. Do not stop using any medications without consulting a doctor.
Co-administration of Methorapfs 20 Injection 0.4 ml with pantoprazole can increase the levels and side effects of Methorapfs 20 Injection 0.4 ml.
How to manage the interaction:
Although there is a possible interaction between pantoprazole and Methorapfs 20 Injection 0.4 ml, you can take these medicines together if prescribed by a doctor. However, if you experience any symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, tiredness, weakness, or dizziness, consult a doctor. Do not stop using any medications without consulting a doctor.
MethotrexatePhenylbutazone
Severe
How does the drug interact with Methorapfs 20 Injection 0.4 ml:
Coadministration of phenylbutazone with Methorapfs 20 Injection 0.4 ml may increase the levels and side effects of phenylbutazone.
How to manage the interaction:
Although there is a possible interaction between phenylbutazone and Methorapfs 20 Injection 0.4 ml, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as mouth ulcers or sores, vomiting, fever, chills, body aches, sore throat, muscle weakness, diarrhea, rash, loss of appetite, joint pain or swelling, yellow discoloration of skin and eyes, dark urine, breathing difficulty, dry cough, paleness, dizziness or fainting, unusual bruising or bleeding, seizures(fits), Consult a doctor. Do not stop using any medications without consulting a doctor.
Coadministration of phenylbutazone with Methorapfs 20 Injection 0.4 ml may increase the levels and side effects of phenylbutazone.
How to manage the interaction:
Although there is a possible interaction between phenylbutazone and Methorapfs 20 Injection 0.4 ml, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as mouth ulcers or sores, vomiting, fever, chills, body aches, sore throat, muscle weakness, diarrhea, rash, loss of appetite, joint pain or swelling, yellow discoloration of skin and eyes, dark urine, breathing difficulty, dry cough, paleness, dizziness or fainting, unusual bruising or bleeding, seizures(fits), Consult a doctor. Do not stop using any medications without consulting a doctor.
Severe
How does the drug interact with Methorapfs 20 Injection 0.4 ml:
Co-administration of Sirolimus with Methorapfs 20 Injection 0.4 ml can increase the risk or severity of kidney damage.
How to manage the interaction:
Although there is a possible interaction between sirolimus and Methorapfs 20 Injection 0.4 ml, you can take these medicines together if prescribed by a doctor. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
Co-administration of Sirolimus with Methorapfs 20 Injection 0.4 ml can increase the risk or severity of kidney damage.
How to manage the interaction:
Although there is a possible interaction between sirolimus and Methorapfs 20 Injection 0.4 ml, you can take these medicines together if prescribed by a doctor. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
Drug-Food Interactions
METHOTREXATE-20MGCaffeine containing foods/drinks
Moderate
Drug-Food Interactions
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METHOTREXATE-20MGCaffeine containing foods/drinks
Moderate
Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu
How to manage the interaction:
Caffeine may reduce the effectiveness of Methorapfs 20 Injection 0.4 ml. Avoid taking caffeine while taking Methorapfs 20 Injection 0.4 ml. This can increase the risk or severity of side effects.
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu
How to manage the interaction:
Caffeine may reduce the effectiveness of Methorapfs 20 Injection 0.4 ml. Avoid taking caffeine while taking Methorapfs 20 Injection 0.4 ml. This can increase the risk or severity of side effects.
Methorapfs 20 Injection 0.4 ml Substitute
Product Substitutes
Alcohol
Unsafe
You are recommended to avoid alcohol consumption while taking Methorapfs 20 Injection 0.4 ml.
Pregnancy
Unsafe
Methorapfs 20 Injection 0.4 ml may cause serious birth defects. It is not recommended to take Methorapfs 20 Injection 0.4 ml while you are pregnant.
Breast Feeding
Unsafe
Methorapfs 20 Injection 0.4 ml passes into breast milk. Avoid breastfeeding whilst on treatment with Methorapfs 20 Injection 0.4 ml and for at least 1 week after the last dose.
Driving
Caution
Methorapfs 20 Injection 0.4 ml may cause dizziness and tiredness; do not drive or operate heavy machinery until you know how Methorapfs 20 Injection 0.4 ml affects you.
Liver
Caution
Please consult your doctor if you have liver impairment before taking Methorapfs 20 Injection 0.4 ml.
Kidney
Caution
Please consult your doctor if you have kidney impairment before taking Methorapfs 20 Injection 0.4 ml.
Children
Caution
The efficacy and safety of Methorapfs 20 Injection 0.4 ml in children have been established in polyarticular-course juvenile rheumatoid arthritis and cancer chemotherapy. Please consult your doctor if you have any concerns regarding the usage of Methorapfs 20 Injection 0.4 ml in children.
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