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About Methotex 1000 mg Injection
Methotex 1000 mg Injection belongs to the class of medicines called 'anti-metabolites and immunosuppressants' used to treat active rheumatoid arthritis, including polyarticular juvenile rheumatoid arthritis and severe psoriasis. Methotex 1000 mg Injection is also used to treat cancer such as breast cancer, cervical cancer, bladder cancer, ovarian cancer, testicular cancer, lung cancer, head and neck cancer, mycosis fungoides (type of blood cancer), bone cancer, and advanced stage non-Hodgkin's lymphomas (cancer that starts in the lymphatic system).
Methotex 1000 mg Injection contains 'Methotrexate' that works by interrupting the processes of the immune system that cause inflammation in the joint tissues. It reduces pain and inflammation and delays joint damage and disease progression over time. Besides this, Methotex 1000 mg Injection prevents and stops the growth of cancer cells, thereby helps treat cancer. Methotex 1000 mg Injection treats psoriasis by suppressing the overactive immune system that is responsible for causing psoriasis.
Methotex 1000 mg Injection will be administered by a qualified healthcare professional; do not self-administer. In some cases, Methotex 1000 mg Injection may cause side-effects such as nausea, vomiting, diarrhoea, unusual fatigue, dizziness, headache, loss of appetite, lowered resistance to infections, tingling sensation, leukopenia (decreased number of white blood cells), and soreness of mouth and lips. You are advised to talk to your doctor if you experience any of the side effects persistently.
Do not take Methotex 1000 mg Injection if you are pregnant or breastfeeding. Methotex 1000 mg Injection may cause dizziness and fatigue, so avoid driving or operating machinery. Avoid consuming alcohol whilst on treatment with Methotex 1000 mg Injection. If you are due to undergo any surgery, including dental surgery, inform the doctor that you are receiving Methotex 1000 mg Injection. Do not have any vaccinations during treatment with Methotex 1000 mg Injection without consulting your doctor. Inform your doctor about your medications and health condition to rule out any unpleasant side effects.
Uses of Methotex 1000 mg Injection
Directions for Use
Medicinal Benefits
Methotex 1000 mg Injection belongs to the class of medicines called 'anti-metabolites and immunosuppressants' used to treat active rheumatoid arthritis including polyarticular juvenile rheumatoid arthritis (arthritis in children) and severe psoriasis. Methotex 1000 mg Injection helps treat rheumatoid arthritis by interrupting the processes of the immune system that cause inflammation in the joint tissues. It reduces pain and inflammation and delays joint damage and disease progression over time. Methotex 1000 mg Injection treats psoriasis by suppressing the overactive immune system that is responsible for causing psoriasis. Methotex 1000 mg Injection is used to treat breast cancer, lung cancer, head and neck cancer, mycosis fungoides (type of blood cancer), and advanced stage non-Hodgkin's lymphomas (cancer that starts in the lymphatic system). Methotex 1000 mg Injection prevents and stops the growth of cancer cells by interfering with DNA production.
How Methotex 1000 mg Injection Works
Storage
What if I have taken an overdose of Methotex 1000 mg Injection
Drug Warnings
Do not take Methotex 1000 mg Injection if you are allergic to any of its contents; if you are pregnant or breastfeeding. Inform your doctor if you have immunodeficiency conditions, bone marrow problems, low white blood cell count, low platelet count, serious anaemia, liver problems due to alcohol abuse, liver, lung or kidney problems, ulceration in the stomach or bowels, poor general condition, received any vaccinations or if are due to have any, diabetes, ascites (fluid in the stomach area), lung problems or fluid in the lungs. Methotex 1000 mg Injection may cause a serious, life-threatening reaction. If you experience symptoms such as rash, itching, hives, throat tightness, trouble swallowing, swelling of the face, throat, lips, or tongue; runny or stuffy nose, lightheadedness or dizziness, chest pain, difficulty breathing, wheezing, or feeling faint, consult your doctor immediately. Inform your doctor if you are undergoing radiation therapy; if you receive Methotex 1000 mg Injection while you are being treated with radiation therapy for cancer, it may cause damage to the skin, bones, or other parts of the body.
Drug-Drug Interactions
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Drug-Food Interactions
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Diet & Lifestyle Advise
Arthritis:
Psoriasis:
Cancer:
Habit Forming
Therapeutic Class
Product Substitutes
Alcohol
Unsafe
You are recommended to avoid alcohol consumption while taking Methotex 1000 mg Injection.
Pregnancy
Unsafe
Methotex 1000 mg Injection may cause serious birth defects. It is not recommended to take Methotex 1000 mg Injection while you are pregnant.
Breast Feeding
Unsafe
Methotex 1000 mg Injection passes into breast milk. Avoid breastfeeding whilst on treatment with Methotex 1000 mg Injection and for at least 1 week after the last dose.
Driving
Caution
Methotex 1000 mg Injection may cause dizziness and tiredness; do not drive or operate heavy machinery until you know how Methotex 1000 mg Injection affects you.
Liver
Caution
Please consult your doctor if you have liver impairment before taking Methotex 1000 mg Injection.
Kidney
Caution
Please consult your doctor if you have kidney impairment before taking Methotex 1000 mg Injection.
Children
Caution
The efficacy and safety of Methotex 1000 mg Injection in children have been established in polyarticular-course juvenile rheumatoid arthritis and cancer chemotherapy. Please consult your doctor if you have any concerns regarding the usage of Methotex 1000 mg Injection in children.
Have a query?
Methotex 1000 mg Injection acts as an immunosuppressant, which helps in reducing inflammation and prevents joint stiffness, thereby providing relief from rheumatoid arthritis.
Methotex 1000 mg Injection works by suppressing the overactive immune system that is responsible for causing psoriasis. Methotex 1000 mg Injection interferes with the synthesis of genetic material (DNA) and the growth of cells that multiply faster than usual, thereby helping in treating psoriasis.
Methotex 1000 mg Injection may affect fertility in men and women. Consult your doctor if you have any concerns regarding this.
Methotex 1000 mg Injection causes leukopenia (decreased number of white blood cells) and hence may make you more susceptible to infections. Consult your doctor if you develop any signs of infections such as fever, sore throat, breathlessness, jaundice, unexplained bleeding or bruising.
Methotex 1000 mg Injection may make your skin sensitive to sunlight. Therefore, avoid prolonged or unnecessary exposure to sunlight or ultraviolet light such as tanning beds and sunlamps. Wear protective clothing, sunglasses, and sunscreen while going out.
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