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  3. Metrogyl 400 Tablet 15's

Metrogyl 400 Tablet 15's, Pack of 15 TABLETS
Metrogyl 400 Tablet 15's, Pack of 15 TABLETS
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Metrogyl 400 Tablet is used to treat and prevent bacterial and parasitic infections, including blood, brain, bone, lung, stomach lining, pelvic area and genital infections, amoebiasis, gum and teeth infections, infected leg ulcers or pressure sores, stomach ulcers caused by Helicobacter pylori, urinary or genital infections caused by the Trichomonas parasite. Furthermore, it can also be used to treat infections that occur after childbirth or wound infections following surgery. It contains Metronidazole, which stops the growth of infection-causing bacteria or parasites. It may cause common side effects such as nausea, vomiting, upset stomach, loss of appetite, dry mouth, and a metallic taste. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and any pre-existing medical conditions.

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Composition :

METRONIDAZOLE-400MG

Manufacturer/Marketer :

J B Chemicals & Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Metrogyl 400 Tablet

Metrogyl 400 Tablet belongs to a group of medicines called Antimicrobials,' used to treat bacterial infections of the blood, brain, lung, bone, pelvic area, stomach lining, intestines, gum, teeth, following childbirth, or wound infection following an operation. It is also used to treat infected leg ulcers, pressure sores, stomach ulcers caused by Helicobacter pylori, urinary or genital infections caused by the Trichomonas parasite, amoebiasis (parasitic infection of the colon), and to prevent infections after surgery.

Metrogyl 400 Tablet contains metronidazole, which works by preventing the production of proteins required by the harmful microorganisms for their survival. Thereby, Metrogyl 400 Tablet treats bacterial and parasitic infections.

Your doctor will decide the dose and duration depending on the type of infection. Some common side effects of Metrogyl 400 Tablet are nausea, vomiting, upset stomach, loss of appetite, dry mouth, and a metallic taste. Most of these side effects do not require medical attention and typically resolve on their own over time. However, if the side effects persist or worsen, please consult your doctor.

Do not take Metrogyl 400 Tablet if you are allergic to any of its components. Metrogyl 400 Tablet should not be used during pregnancy, especially during the first trimester and while breastfeeding. Do not drive or operate heavy machinery after taking Metrogyl 400 Tablet , as it may cause dizziness and drowsiness. Avoid consumption of alcohol while on treatment with Metrogyl 400 Tablet and for 48 hours after completing the course, as it may cause unpleasant side effects. Keep your doctor informed about your health condition and any medications you are taking to help rule out any potential side effects.

Uses of Metrogyl 400 Tablet

Metrogyl 400 Tablet is used to treat bacterial and protozoal infections. The detailed uses of Metrogyl 400 Tablet are as follows:<br/> • Bacterial infections: Metrogyl 400 Tablet is widely used to treat infections caused by anaerobic bacteria, including those affecting the lungs, throat, bone and joints, skin and soft tissues, blood, brain, pelvic area, stomach lining, and intestines.<br/> • Protozoal infections: Metrogyl 400 Tablet is effective against protozoa such as Entamoeba histolytica (linked to amoebic dysentery); it inhibits protozoal reproduction. It is also used to treat urinary or genital infections caused by the Trichomonas parasite.<br/> • Dental infections: Metrogyl 400 Tablet is often prescribed in dentistry to address gum and oral cavity infections, particularly those caused by anaerobic bacteria. It may be used in combination with other antibiotics for enhanced effectiveness.<br/> • Helicobacter Pylori Eradication: Metrogyl 400 Tablet is used as part of a combination therapy to eradicate Helicobacter pylori, a bacterium associated with peptic ulcers. It is typically used alongside other antibiotics and proton pump inhibitors.<br/> • Further Applications: Metrogyl 400 Tablet is also used to treat bacterial infections following childbirth or wound infections after surgery.<br/>

Directions for Use

  • Metrogyl 400 Tablet can be taken with or without food. However, if it causes stomach discomfort, taking it with food may help.
  • Take it exactly as prescribed by your doctor, who will determine the appropriate dose and timing based on the severity of your infection.
  • Swallow it whole with a glass of water.
  • Do not crush, chew, or break it.

Medicinal Benefits

Metrogyl 400 Tablet contains metronidazole used to treat and prevent bacterial and parasitic infections, including blood, brain, bone, lung, stomach lining, pelvic area and genital infections, amoebiasis, gum and teeth infections, infected leg ulcers or pressure sores, stomach ulcers caused by Helicobacter pylori, urinary or genital infections caused by Trichomonas parasite. Furthermore, it can also be used to treat infections that occur after childbirth or wound infections that follow surgery. It works by preventing the production of proteins required by the harmful microorganisms for their survival. Thereby, Metrogyl 400 Tablet helps treat bacterial and parasitic infections.

How Metrogyl 400 Tablet Works

Metrogyl 400 Tablet contains metronidazole, which works by preventing the production of proteins required by the harmful microorganisms for their survival. Thereby, Metrogyl 400 Tablet treats bacterial and parasitic infections.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Metrogyl 400 Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Manage stress by practising deep breathing, yoga or meditation.
  • Participating in activities you enjoy, or exercising may also help manage agitation.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Exercise regularly. Try physical activities like walking, running, or dancing.
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.
  • Eat a balanced diet rich in fruits, vegetables, and whole grains to support overall health.
  • Include foods high in omega-3 fatty acids, like salmon and walnuts, to support eye health.
  • Stay hydrated by drinking plenty of water.
  • Engage in regular physical activity, like walking or yoga, to improve mobility and balance.
  • Practice stress-reducing techniques, like meditation or deep breathing, to manage emotional challenges.
  • Establish a daily routine to maintain independence and organization.
  • Consider learning Braille or using assistive technologies to enhance daily life.
Managing depression as a side effect of medication: a comprehensive guide.
  • Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
  • Tell your doctor about your depression symptoms to adjust medication.
  • Consult a therapist or counsel for emotional support.
  • Engage in regular exercise to release endorphins (neurotransmitters).
  • Practice stress-reducing techniques like meditation and deep breathing.
  • Build a support network of friends, family, and support groups.
  • Establish a consistent sleep schedule.
  • Eat a nutritious diet rich in fruits, vegetables, and whole grains.
  • Limit or avoid alcohol and recreational substances.
  • Keep a mood journal to track symptoms and progress.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.

What if I have taken an overdose of Metrogyl 400 Tablet

Do not take more than the prescribed dose of Metrogyl 400 Tablet , as it may cause an overdose. The symptoms of an overdose include nausea, vomiting, seizures (fits), loss of muscle coordination, and numbness, burning, pain, or tingling in the hands or feet. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Metrogyl 400 Tablet if you are allergic to any of its components. Metrogyl 400 Tablet should not be used during pregnancy, especially during the first trimester. Please inform your doctor if you are pregnant or planning to become pregnant. Avoid breastfeeding while taking Metrogyl 400 Tablet and for 12-24 hours after completing the course. Do not drive or operate heavy machinery after taking Metrogyl 400 Tablet , as it may cause dizziness and drowsiness. Inform your doctor before taking Metrogyl 400 Tablet if you have any medical conditions, such as Clostridium difficile-associated diarrhoea, bone marrow depression/low blood count, CNS disorder, epilepsy, porphyria (blood disorder), peripheral neuropathy, or heart, liver, or kidney problems.

Drug-Drug Interactions

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MetronidazoleEthanol
Critical
MetronidazoleDisulfiram
Critical

Drug-Drug Interactions

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MetronidazoleEthanol
Critical
How does the drug interact with Metrogyl 400 Tablet:
Drinking alcohol while taking Metrogyl 400 Tablet can increase the risk or severity of side effects.

How to manage the interaction:
Taking Metrogyl 400 Tablet with Ethanol is avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience flushing, throbbing in head and neck, throbbing headache, difficulty breathing, nausea, vomiting, sweating, thirst, chest pain, rapid heartbeat, palpitation, low blood pressure, dizziness, lightheadedness, blurred vision, and confusion, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MetronidazoleDisulfiram
Critical
How does the drug interact with Metrogyl 400 Tablet:
Coadministration of Disulfiram with Metrogyl 400 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Metrogyl 400 Tablet and Disulfiram together is generally avoided as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, confusion, weakness, shortness of breath, or palpitations, contact your doctor. Do not discontinue any medications without consulting a doctor.
MetronidazoleAmprenavir
Critical
How does the drug interact with Metrogyl 400 Tablet:
Co-administration of Amprenavir with Metrogyl 400 Tablet can increase the risk or severity of side effects.

How to manage the interaction:
Taking Metrogyl 400 Tablet with Amprenavir is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience throbbing in the head and neck, throbbing headache, difficulty breathing, nausea, vomiting, sweating, thirst, chest pain, rapid heartbeat, palpitation, low blood pressure, dizziness, lightheadedness, blurred vision, and confusion, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MetronidazoleBusulfan
Severe
How does the drug interact with Metrogyl 400 Tablet:
Coadministration of Busulfan and Metrogyl 400 Tablet may increase the risk of side effects.

How to manage the interaction:
Taking Metrogyl 400 Tablet and Busulfan together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience unusual bruising or bleeding, fever, diarrhea, sore throat, muscle aches, shortness of breath, or burning during urination, contact a doctor immediately. Do not discontinue the medication without a doctor's advice.
MetronidazoleMebendazole
Severe
How does the drug interact with Metrogyl 400 Tablet:
Coadministration of Metrogyl 400 Tablet with mebendazole may increase the risk or severity of side effects.

How to manage the interaction:
Although there is a possible interaction between Metrogyl 400 Tablet and mebendazole, they can be taken together if your doctor has prescribed them. However, if you experience any unusual symptoms like fever, body ache, painful red rash, cough, peeling of the skin, or Drooling, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
MetronidazoleWarfarin
Severe
How does the drug interact with Metrogyl 400 Tablet:
Coadministration of Metrogyl 400 Tablet with warfarin can increase the risk of bleeding.

How to manage the interaction:
There is a possible interaction between Metrogyl 400 Tablet and warfarin, but they can be taken together if a doctor has prescribed them. Consult a doctor if experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not stop using any medications without talking to a doctor.
MetronidazoleFluconazole
Moderate
How does the drug interact with Metrogyl 400 Tablet:
Co-administration of Fluconazole together with Metrogyl 400 Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
-Taking Metrogyl 400 Tablet with Fluconazole together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • It would be best to take probiotics after taking the full course of Metrogyl 400 Tablet to restore healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods, such as yoghurt, cheese, sauerkraut, and kimchi, can help restore the intestines' good bacteria.
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria, which helps stimulate their growth. Whole grains, such as whole-grain bread and brown rice, should be included in the diet.
  • Avoid intake of alcoholic beverages with Metrogyl 400 Tablet as it can make you dehydrated and affect your sleep. This can make it harder for your body to help Metrogyl 400 Tablet fight off infections.
  • If you have diarrhoea, drink appropriate amounts of fluids to avoid dehydration.

Habit Forming

No

Therapeutic Class

ANTIMICROBIALS

Metrogyl 400 Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

You are recommended not to consume alcohol while on treatment with Metrogyl 400 Tablet and for 48 hours after completing the course to avoid unpleasant side effects such as nausea, vomiting, stomach pain, palpitations, headache, and hot flushes.

bannner image

Pregnancy

Unsafe

Metrogyl 400 Tablet should not be used during pregnancy, especially during the first trimester. Inform your doctor if you are pregnant or planning to become pregnant.

bannner image

Breast Feeding

Unsafe

Metrogyl 400 Tablet may pass into breast milk. Avoid breastfeeding while taking Metrogyl 400 Tablet and for 12-24 hours after completing the course.

bannner image

Driving

Caution

Metrogyl 400 Tablet may cause dizziness and drowsiness; therefore, avoid driving or operating machinery unless you are alert.

bannner image

Liver

Caution

Metrogyl 400 Tablet should be taken with caution, especially if you have a history of liver diseases/conditions. Your doctor may adjust your dose depending on your liver condition.

bannner image

Kidney

Caution

Metrogyl 400 Tablet should be taken with caution, especially if you have a history of kidney diseases/conditions. Your doctor may adjust your dose depending on your kidney condition.

bannner image

Children

Safe if prescribed

Metrogyl 400 Tablet should be given to children only if prescribed by a doctor. Your doctor may adjust the dose as per the age of your child.

Have a query?

FAQs

Metrogyl 400 Tablet is used to treat and prevent bacterial and parasitic infections, including blood, brain, bone, lung, stomach lining, pelvic area and genital infections, amoebiasis, gum and teeth infections, infected leg ulcers or pressure sores, stomach ulcers caused by Helicobacter pylori, urinary or genital infections caused by the Trichomonas parasite. Furthermore, it can also be used to treat infections that occur after childbirth or wound infections following surgery.

Metrogyl 400 Tablet works by preventing the production of proteins required by harmful microorganisms for their survival. Thereby, Metrogyl 400 Tablet helps treat and prevent bacterial and parasitic infections.

No. You should complete the full course of Metrogyl 400 Tablet as prescribed by your doctor. Consult your doctor if you experience any difficulty while taking Metrogyl 400 Tablet .

No. Metrogyl 400 Tablet is an antimicrobial medicine that acts only against bacterial infections, not against viral infections such as the common cold and flu.

If you miss a dose of Metrogyl 400 Tablet , take it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and follow your regular schedule. Never take a double dose to make up for the missed one.

Metrogyl 400 Tablet may cause jaundice in a rare case. Please consult your doctor immediately if you notice yellowing of the skin and eyes.

No. Do not stop taking Metrogyl 400 Tablet until the course is completed, as prescribed by the doctor. If you stop taking it, your problem may reoccur. If you experience any difficulty or adverse events that persist while taking it, report them to your doctor and seek appropriate treatment.

Metrogyl 400 Tablet may also be used with other medications to treat certain stomach/intestinal ulcers caused by a bacteria (H. pylori). Even so, it can only be used if advised by a doctor.

Do not take more than the prescribed dose of Metrogyl 400 Tablet , as it may cause an overdose. The symptoms of an overdose include nausea, vomiting, seizures (fits), loss of muscle coordination, and numbness, burning, pain, or tingling in the hands or feet. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

If the symptoms do not improve within a few days after starting this medicine or if they worsen, consult your doctor. They will reassess the condition and provide guidance on appropriate treatment.

Metrogyl 400 Tablet may interact with certain medications. So, do not use any other medications with Metrogyl 400 Tablet unless recommended by the doctor. Your doctor will check for potential interactions and prescribe you if necessary.

Antibiotics like Metrogyl 400 Tablet may reduce the vaccine's activity. To ensure an adequate vaccine response, vaccination should be administered at least 14 days after completing treatment with Metrogyl 400 Tablet or 10 days before starting therapy with Metrogyl 400 Tablet . Talk to your doctor if you have any questions or concerns.

Let your doctor know about your child’s medical history and ongoing medications before prescribing Metrogyl 400 Tablet .

Yes, it is normal. Metrogyl 400 Tablet can cause urine discolouration. This is harmless and should resolve on its own once your child stops taking the medication.

Metrogyl 400 Tablet may interfere with some drugs. Always check with a doctor before giving any medication, especially if your child is feverish. The doctor will advise the best course of treatment for your child.

To ensure the medication's effectiveness and progress of the medical condition, the doctor may perform certain lab tests, such as a complete blood count (CBC), liver function test (LFT), and kidney function test (KFT) if necessary.

Common side effects of Metrogyl 400 Tablet may include nausea, vomiting, upset stomach, loss of appetite, dry mouth, and a metallic taste. Most of these side effects do not require medical attention and will gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Cnergy IT Park, 3rd floor Appa Saheb Marathe Marg, Prabhadevi, Mumbai 400025
Other Info - MET0053

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 23, 2025 | 7:28 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.drugs.com/metronidazole.html
  2. https://medlineplus.gov/druginfo/meds/a689011.html
  3. https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=93e4f174-4fe0-4cfd-a0cf-d0963e082107
  4. https://labeling.pfizer.com/showlabeling.aspx?id=570
  5. https://www.medsafe.govt.nz/Consumers/cmi/m/Metrogyl.pdf
  6. https://webmedpharmacy.co.uk/media/pil/sti/PIL_metronidazole_400mg_tabs.pdf
  7. https://www.nhs.uk/medicines/metronidazole/about-metronidazole/
  8. https://www.medicines.org.uk/emc/files/pil.5882.pdf
  9. https://www.drugs.com/drug-interactions/metronidazole-index.html?filter=3

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