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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Metrogyl ER Tablet is used to treat and prevent bacterial and parasitic infections, including blood, brain, bone, lung, stomach lining, pelvic area and genital infections, amoebiasis, gum and teeth infections, infected leg ulcers or pressure sores, stomach ulcers caused by Helicobacter pylori, urinary or genital infections caused by the Trichomonas parasite. Furthermore, it can also be used to treat infections that occur after childbirth or wound infections following surgery. It contains Metronidazole, which stops the growth of infection-causing bacteria or parasites. It may cause common side effects such as nausea, vomiting, upset stomach, loss of appetite, dry mouth, and a metallic taste. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and any pre-existing medical conditions.

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Whats That

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Composition :

METRONIDAZOLE-600MG

Manufacturer/Marketer :

Lekar Pharma Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Metrogyl ER Tablet

Metrogyl ER Tablet belongs to a group of medicines called Antimicrobials,' used to treat bacterial infections of the blood, brain, lung, bone, pelvic area, stomach lining, intestines, gum, teeth, following childbirth, or wound infection following an operation. It is also used to treat infected leg ulcers, pressure sores, stomach ulcers caused by Helicobacter pylori, urinary or genital infections caused by the Trichomonas parasite, amoebiasis (parasitic infection of the colon), and to prevent infections after surgery.

Metrogyl ER Tablet contains metronidazole, which works by preventing the production of proteins required by the harmful microorganisms for their survival. Thereby, Metrogyl ER Tablet treats bacterial and parasitic infections.

Your doctor will decide the dose and duration depending on the type of infection. Some common side effects of Metrogyl ER Tablet are nausea, vomiting, upset stomach, loss of appetite, dry mouth, and a metallic taste. Most of these side effects do not require medical attention and typically resolve on their own over time. However, if the side effects persist or worsen, please consult your doctor.

Do not take Metrogyl ER Tablet if you are allergic to any of its components. Metrogyl ER Tablet should not be used during pregnancy, especially during the first trimester and while breastfeeding. Do not drive or operate heavy machinery after taking Metrogyl ER Tablet , as it may cause dizziness and drowsiness. Avoid consumption of alcohol while on treatment with Metrogyl ER Tablet and for 48 hours after completing the course, as it may cause unpleasant side effects. Keep your doctor informed about your health condition and any medications you are taking to help rule out any potential side effects.

Uses of Metrogyl ER Tablet

Metrogyl ER Tablet is used to treat bacterial and protozoal infections. The detailed uses of Metrogyl ER Tablet are as follows:<br/> • Bacterial infections: Metrogyl ER Tablet is widely used to treat infections caused by anaerobic bacteria, including those affecting the lungs, throat, bone and joints, skin and soft tissues, blood, brain, pelvic area, stomach lining, and intestines.<br/> • Protozoal infections: Metrogyl ER Tablet is effective against protozoa such as Entamoeba histolytica (linked to amoebic dysentery); it inhibits protozoal reproduction. It is also used to treat urinary or genital infections caused by the Trichomonas parasite.<br/> • Dental infections: Metrogyl ER Tablet is often prescribed in dentistry to address gum and oral cavity infections, particularly those caused by anaerobic bacteria. It may be used in combination with other antibiotics for enhanced effectiveness.<br/> • Helicobacter Pylori Eradication: Metrogyl ER Tablet is used as part of a combination therapy to eradicate Helicobacter pylori, a bacterium associated with peptic ulcers. It is typically used alongside other antibiotics and proton pump inhibitors.<br/> • Further Applications: Metrogyl ER Tablet is also used to treat bacterial infections following childbirth or wound infections after surgery.<br/>

Directions for Use

  • Metrogyl ER Tablet can be taken with or without food. However, if it causes stomach discomfort, taking it with food may help.
  • Take it exactly as prescribed by your doctor, who will determine the appropriate dose and timing based on the severity of your infection.
  • Swallow it whole with a glass of water.
  • Do not crush, chew, or break it.

Medicinal Benefits

Metrogyl ER Tablet contains metronidazole used to treat and prevent bacterial and parasitic infections, including blood, brain, bone, lung, stomach lining, pelvic area and genital infections, amoebiasis, gum and teeth infections, infected leg ulcers or pressure sores, stomach ulcers caused by Helicobacter pylori, urinary or genital infections caused by Trichomonas parasite. Furthermore, it can also be used to treat infections that occur after childbirth or wound infections that follow surgery. It works by preventing the production of proteins required by the harmful microorganisms for their survival. Thereby, Metrogyl ER Tablet helps treat bacterial and parasitic infections.

How Metrogyl ER Tablet Works

Metrogyl ER Tablet contains metronidazole, which works by preventing the production of proteins required by the harmful microorganisms for their survival. Thereby, Metrogyl ER Tablet treats bacterial and parasitic infections.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Metrogyl ER Tablet

Do not take more than the prescribed dose of Metrogyl ER Tablet , as it may cause an overdose. The symptoms of an overdose include nausea, vomiting, seizures (fits), loss of muscle coordination, and numbness, burning, pain, or tingling in the hands or feet. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Metrogyl ER Tablet if you are allergic to any of its components. Metrogyl ER Tablet should not be used during pregnancy, especially during the first trimester. Please inform your doctor if you are pregnant or planning to become pregnant. Avoid breastfeeding while taking Metrogyl ER Tablet and for 12-24 hours after completing the course. Do not drive or operate heavy machinery after taking Metrogyl ER Tablet , as it may cause dizziness and drowsiness. Inform your doctor before taking Metrogyl ER Tablet if you have any medical conditions, such as Clostridium difficile-associated diarrhoea, bone marrow depression/low blood count, CNS disorder, epilepsy, porphyria (blood disorder), peripheral neuropathy, or heart, liver, or kidney problems.

Drug-Drug Interactions

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MetronidazoleAmprenavir
Critical
Critical

Drug-Drug Interactions

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MetronidazoleAmprenavir
Critical
How does the drug interact with Metrogyl ER Tablet:
Co-administration of Amprenavir with Metrogyl ER Tablet can increase the risk or severity of side effects.

How to manage the interaction:
Taking Metrogyl ER Tablet with Amprenavir is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience throbbing in the head and neck, throbbing headache, difficulty breathing, nausea, vomiting, sweating, thirst, chest pain, rapid heartbeat, palpitation, low blood pressure, dizziness, lightheadedness, blurred vision, and confusion, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Critical
How does the drug interact with Metrogyl ER Tablet:
Drinking alcohol while taking Metrogyl ER Tablet can increase the risk or severity of side effects.

How to manage the interaction:
Taking Metrogyl ER Tablet with Ethanol is avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience flushing, throbbing in head and neck, throbbing headache, difficulty breathing, nausea, vomiting, sweating, thirst, chest pain, rapid heartbeat, palpitation, low blood pressure, dizziness, lightheadedness, blurred vision, and confusion, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Metrogyl ER Tablet:
Coadministration of Disulfiram with Metrogyl ER Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Metrogyl ER Tablet and Disulfiram together is generally avoided as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, confusion, weakness, shortness of breath, or palpitations, contact your doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Metrogyl ER Tablet:
Coadministration of Busulfan and Metrogyl ER Tablet may increase the risk of side effects.

How to manage the interaction:
Taking Metrogyl ER Tablet and Busulfan together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience unusual bruising or bleeding, fever, diarrhea, sore throat, muscle aches, shortness of breath, or burning during urination, contact a doctor immediately. Do not discontinue the medication without a doctor's advice.
How does the drug interact with Metrogyl ER Tablet:
Coadministration of Metrogyl ER Tablet with warfarin can increase the risk of bleeding.

How to manage the interaction:
There is a possible interaction between Metrogyl ER Tablet and warfarin, but they can be taken together if a doctor has prescribed them. Consult a doctor if experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not stop using any medications without talking to a doctor.
How does the drug interact with Metrogyl ER Tablet:
Coadministration of Metrogyl ER Tablet with mebendazole may increase the risk or severity of side effects.

How to manage the interaction:
Although there is a possible interaction between Metrogyl ER Tablet and mebendazole, they can be taken together if your doctor has prescribed them. However, if you experience any unusual symptoms like fever, body ache, painful red rash, cough, peeling of the skin, or Drooling, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Metrogyl ER Tablet:
Co-administration of Fluconazole together with Metrogyl ER Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
-Taking Metrogyl ER Tablet with Fluconazole together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • It would be best to take probiotics after taking the full course of Metrogyl ER Tablet to restore healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods, such as yoghurt, cheese, sauerkraut, and kimchi, can help restore the intestines' good bacteria.
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria, which helps stimulate their growth. Whole grains, such as whole-grain bread and brown rice, should be included in the diet.
  • Avoid intake of alcoholic beverages with Metrogyl ER Tablet as it can make you dehydrated and affect your sleep. This can make it harder for your body to help Metrogyl ER Tablet fight off infections.
  • If you have diarrhoea, drink appropriate amounts of fluids to avoid dehydration.

Habit Forming

No

Therapeutic Class

ANTIMICROBIALS
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Alcohol

Unsafe

You are recommended not to consume alcohol while on treatment with Metrogyl ER Tablet and for 48 hours after completing the course to avoid unpleasant side effects such as nausea, vomiting, stomach pain, palpitations, headache, and hot flushes.

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Pregnancy

Unsafe

Metrogyl ER Tablet should not be used during pregnancy, especially during the first trimester. Inform your doctor if you are pregnant or planning to become pregnant.

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Breast Feeding

Unsafe

Metrogyl ER Tablet may pass into breast milk. Avoid breastfeeding while taking Metrogyl ER Tablet and for 12-24 hours after completing the course.

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Driving

Caution

Metrogyl ER Tablet may cause dizziness and drowsiness; therefore, avoid driving or operating machinery unless you are alert.

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Liver

Caution

Metrogyl ER Tablet should be taken with caution, especially if you have a history of liver diseases/conditions. Your doctor may adjust your dose depending on your liver condition.

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Kidney

Caution

Metrogyl ER Tablet should be taken with caution, especially if you have a history of kidney diseases/conditions. Your doctor may adjust your dose depending on your kidney condition.

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Children

Safe if prescribed

Metrogyl ER Tablet should be given to children only if prescribed by a doctor. Your doctor may adjust the dose as per the age of your child.

Have a query?

FAQs

Metrogyl ER Tablet is used to treat and prevent bacterial and parasitic infections, including blood, brain, bone, lung, stomach lining, pelvic area and genital infections, amoebiasis, gum and teeth infections, infected leg ulcers or pressure sores, stomach ulcers caused by Helicobacter pylori, urinary or genital infections caused by the Trichomonas parasite. Furthermore, it can also be used to treat infections that occur after childbirth or wound infections following surgery.

Metrogyl ER Tablet works by preventing the production of proteins required by harmful microorganisms for their survival. Thereby, Metrogyl ER Tablet helps treat and prevent bacterial and parasitic infections.

No. You should complete the full course of Metrogyl ER Tablet as prescribed by your doctor. Consult your doctor if you experience any difficulty while taking Metrogyl ER Tablet .

No. Metrogyl ER Tablet is an antimicrobial medicine that acts only against bacterial infections, not against viral infections such as the common cold and flu.

If you miss a dose of Metrogyl ER Tablet , take it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and follow your regular schedule. Never take a double dose to make up for the missed one.

Metrogyl ER Tablet may cause jaundice in a rare case. Please consult your doctor immediately if you notice yellowing of the skin and eyes.

No. Do not stop taking Metrogyl ER Tablet until the course is completed, as prescribed by the doctor. If you stop taking it, your problem may reoccur. If you experience any difficulty or adverse events that persist while taking it, report them to your doctor and seek appropriate treatment.

Metrogyl ER Tablet may also be used with other medications to treat certain stomach/intestinal ulcers caused by a bacteria (H. pylori). Even so, it can only be used if advised by a doctor.

Do not take more than the prescribed dose of Metrogyl ER Tablet , as it may cause an overdose. The symptoms of an overdose include nausea, vomiting, seizures (fits), loss of muscle coordination, and numbness, burning, pain, or tingling in the hands or feet. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

If the symptoms do not improve within a few days after starting this medicine or if they worsen, consult your doctor. They will reassess the condition and provide guidance on appropriate treatment.

Metrogyl ER Tablet may interact with certain medications. So, do not use any other medications with Metrogyl ER Tablet unless recommended by the doctor. Your doctor will check for potential interactions and prescribe you if necessary.

Antibiotics like Metrogyl ER Tablet may reduce the vaccine's activity. To ensure an adequate vaccine response, vaccination should be administered at least 14 days after completing treatment with Metrogyl ER Tablet or 10 days before starting therapy with Metrogyl ER Tablet . Talk to your doctor if you have any questions or concerns.

Let your doctor know about your child’s medical history and ongoing medications before prescribing Metrogyl ER Tablet .

Yes, it is normal. Metrogyl ER Tablet can cause urine discolouration. This is harmless and should resolve on its own once your child stops taking the medication.

Metrogyl ER Tablet may interfere with some drugs. Always check with a doctor before giving any medication, especially if your child is feverish. The doctor will advise the best course of treatment for your child.

To ensure the medication's effectiveness and progress of the medical condition, the doctor may perform certain lab tests, such as a complete blood count (CBC), liver function test (LFT), and kidney function test (KFT) if necessary.

Common side effects of Metrogyl ER Tablet may include nausea, vomiting, upset stomach, loss of appetite, dry mouth, and a metallic taste. Most of these side effects do not require medical attention and will gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

SHETH GOVINDRAO SMRITI 83 B&CDR A B ROAD WORLI MUMBAI MH 400018 INDIA
Other Info - MET1616

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