Metronidazole Injection 100ml
MRP ₹12
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About Metronidazole Injection
Metronidazole Injection belongs to a group of medicines known as antibacterial agents used to treat severe bacterial infections of the bone, skin and skin structure, blood, joint, abdomen, central nervous system, respiratory, and gynaecological systems, meningitis (infection of the membranes that surround the brain and spinal cord), and endocarditis (infection of the heart lining and valves).
Metronidazole Injection contains Metronidazole, which suppresses protein synthesis by interacting with DNA and causing helical DNA structure loss and strand breakage. As a result, it induces cell death in susceptible organisms. Thus, Metronidazole Injection treats bacterial infections.
Metronidazole Injection will be administered by a healthcare professional; do not self-administer. Some common side effects of Metronidazole Injection are nausea, vomiting, diarrhoea, constipation, and injection site reaction. These side effects are temporary and may resolve after some time. However, if any of the side effects persist or worsen, contact the doctor.
Let your doctor know if you are allergic to metronidazole. Consult your doctor if you are pregnant, planning to get pregnant, or if you are breastfeeding. Do not operate heavy machinery or drive after taking Metronidazole Injection as it may cause dizziness and drowsiness. Avoid consumption of alcohol while on treatment with Metronidazole Injection as it may cause unpleasant side effects.
Uses of Metronidazole Injection
Metronidazole Injection used in the treatment of bacterial infections. The detailed uses of Metronidazole Injection are as follows:
- Treatment of Infections: Metronidazole Injection effectively treats various infections, including intra-abdominal, skin, gynecologic, septicemia, bone and joint, CNS, respiratory tract, and endocarditis, by eliminating anaerobic bacteria and parasites, stopping their growth, and alleviating symptoms.
- Surgical Prophylaxis: Metronidazole Injection is used as a surgical prophylaxis to prevent postoperative infections, particularly for surgeries involving the gastrointestinal tract.
- Management of Clostridium Difficile Infection: Metronidazole Injection is used to manage severe Clostridium difficile infections, especially when oral medication is not possible.
- Amoebic Dysentery Treatment: Metronidazole Injection is used to treat amoebic dysentery, a severe intestinal infection caused by the Entamoeba histolytica parasite.
- Combination Therapy: Metronidazole Injection is often used in combination with other antibiotics to treat serious infections, offering a broad spectrum of action and enhancing treatment effectiveness.
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Directions for Use
- Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
- Metronidazole Injection will be administered by the doctor or healthcare professional.
- Do not self-administer.
Key Benefits
Metronidazole Injection belongs to a group of medicines known as anti-bacterial agents used to treat severe bacterial infections of the bone, skin and skin structure, blood, joint, abdomen, central nervous system, gynecologic, respiratory infections, meningitis (infection of the membranes that surround the brain and spinal cord), and endocarditis (infection of the heart lining and valves). Metronidazole Injection contains Metronidazole, which suppresses protein synthesis by interacting with DNA and causes helical DNA structure loss and strand breakage. As a result, it induces cell death in susceptible organisms. Thereby, Metronidazole Injection treats bacterial infections.
How Metronidazole Injection Works
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- Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
- Tell your doctor about your depression symptoms to adjust medication.
- Consult a therapist or counsel for emotional support.
- Engage in regular exercise to release endorphins (neurotransmitters).
- Practice stress-reducing techniques like meditation and deep breathing.
- Build a support network of friends, family, and support groups.
- Establish a consistent sleep schedule.
- Eat a nutritious diet rich in fruits, vegetables, and whole grains.
- Limit or avoid alcohol and recreational substances.
- Keep a mood journal to track symptoms and progress.
- Manage stress by practising deep breathing, yoga or meditation.
- Participating in activities you enjoy, or exercising may also help manage agitation.
- Get enough sleep. Maintain a regular sleep cycle.
- Exercise regularly. Try physical activities like walking, running, or dancing.
- Talk to your doctor about your back pain and potential medication substitutes or dose changes.
- Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
- To lessen the tension on your back, sit and stand upright and maintain proper posture.
- To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
- Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
- Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
- To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
- Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
- Back discomfort can worsen by bending, twisting, and heavy lifting.
- Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.
- Eat a balanced diet rich in fruits, vegetables, and whole grains to support overall health.
- Include foods high in omega-3 fatty acids, like salmon and walnuts, to support eye health.
- Stay hydrated by drinking plenty of water.
- Engage in regular physical activity, like walking or yoga, to improve mobility and balance.
- Practice stress-reducing techniques, like meditation or deep breathing, to manage emotional challenges.
- Establish a daily routine to maintain independence and organization.
- Consider learning Braille or using assistive technologies to enhance daily life.
- Get enough sleep. Maintain a regular sleep cycle.
- Eat a healthy diet and exercise regularly.
- Manage stress with yoga or meditation.
- Limit alcohol and caffeine.
- Avoid driving or operating machinery unless you are alert.
- To the affected part, apply warm compresses to get a temporary relief.
- Rinse your eye carefully with clean water and try to blow any dust particle that could have entered.
- Take over the counter medication to lubricate your eye or if there is pain due to allergy to soothe the eye.
- If there is persistent pain in your eye, consult your doctor and follow the medication immediately.
What if I have taken an overdose of Metronidazole Injection
Drug Warnings
Do not take Metronidazole Injection if you are allergic to any of the components. Consult your doctor if you are pregnant, plan to get pregnant or if you are breastfeeding. Do not operate heavy machinery or drive after taking Metronidazole Injection as it may cause dizziness and drowsiness. Inform your doctor if you have bone marrow depression/low blood count, kidney impairment, CNS disorder, liver or heart problems, peripheral neuropathy, epilepsy, Crohn's disease (a condition in which the body attacks the lining of the digestive tract), yeast infection, oedema (swelling), or blood disorders.
Drug-Drug Interactions
Drug-Drug Interactions
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Drinking alcohol while taking Metronidazole Injection 100ml can increase the risk or severity of side effects.
How to manage the interaction:
Taking Metronidazole Injection 100ml with Ethanol is avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience flushing, throbbing in head and neck, throbbing headache, difficulty breathing, nausea, vomiting, sweating, thirst, chest pain, rapid heartbeat, palpitation, low blood pressure, dizziness, lightheadedness, blurred vision, and confusion, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Coadministration of Disulfiram with Metronidazole Injection 100ml can increase the risk of side effects.
How to manage the interaction:
Taking Metronidazole Injection 100ml and Disulfiram together is generally avoided as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, confusion, weakness, shortness of breath, or palpitations, contact your doctor. Do not discontinue any medications without consulting a doctor.
Co-administration of Amprenavir with Metronidazole Injection 100ml can increase the risk or severity of side effects.
How to manage the interaction:
Taking Metronidazole Injection 100ml with Amprenavir is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience throbbing in the head and neck, throbbing headache, difficulty breathing, nausea, vomiting, sweating, thirst, chest pain, rapid heartbeat, palpitation, low blood pressure, dizziness, lightheadedness, blurred vision, and confusion, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Coadministration of Metronidazole Injection 100ml with mebendazole may increase the risk or severity of side effects.
How to manage the interaction:
Although there is a possible interaction between Metronidazole Injection 100ml and mebendazole, they can be taken together if your doctor has prescribed them. However, if you experience any unusual symptoms like fever, body ache, painful red rash, cough, peeling of the skin, or Drooling, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Coadministration of Busulfan and Metronidazole Injection 100ml may increase the risk of side effects.
How to manage the interaction:
Taking Metronidazole Injection 100ml and Busulfan together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience unusual bruising or bleeding, fever, diarrhea, sore throat, muscle aches, shortness of breath, or burning during urination, contact a doctor immediately. Do not discontinue the medication without a doctor's advice.
Coadministration of Metronidazole Injection 100ml with warfarin can increase the risk of bleeding.
How to manage the interaction:
There is a possible interaction between Metronidazole Injection 100ml and warfarin, but they can be taken together if a doctor has prescribed them. Consult a doctor if experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not stop using any medications without talking to a doctor.
Co-administration of Fluconazole together with Metronidazole Injection 100ml can increase the risk of an irregular heart rhythm.
How to manage the interaction:
-Taking Metronidazole Injection 100ml with Fluconazole together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
Drug-Food Interactions
Drug-Food Interactions
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Diet & Lifestyle Advise
- It would be best to take probiotics after taking the full course of Metronidazole Injection to restore healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
- Include more fibre-enriched food in your diet. This food can be easily digested by gut bacteria, which helps stimulate their growth. Whole grains like whole-grain bread and brown rice should also be included in the diet.
- Avoid intake of alcoholic beverages with Metronidazole Injection as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid Metronidazole Injection in fighting off infections.
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Alcohol
Safe if prescribed
You are recommended not to consume alcohol along with Metronidazole Injection to avoid unpleasant side effects such as stomach pain, nausea, vomiting, flushing, and headache.
Pregnancy
Consult your doctor
Please consult your doctor. Metronidazole Injection should be used in pregnant women only if clinically needed, and the benefits outweigh the risks.
Breast Feeding
Consult your doctor
Consult your doctor if you are a nursing mother. Your doctor will weigh the benefits and potential risks before prescribing Metronidazole Injection .
Driving
Safe if prescribed
Metronidazole Injection may cause dizziness and drowsiness; thus, avoid operating machinery or driving vehicles unless you are alert.
Liver
Consult your doctor
Metronidazole Injection to be taken with caution, especially if you have a history of liver diseases/conditions. Your doctor may adjust your dose depending on your liver condition.
Kidney
Consult your doctor
Metronidazole Injection to be taken with extreme caution, especially if you have a history of kidney diseases/conditions. Your doctor may adjust your dose depending on your kidney condition.
Children
Safe if prescribed
Limited information about the use of Metronidazole Injection in paediatric patients. Please seek medical advice. Your doctor will weigh the benefits and risks before prescribing this medicine to your child.
Heart
Metronidazole Injection to be taken with caution, especially if you have a history of heart diseases/conditions. Your doctor may adjust your dose depending on your liver condition.
Geriatrics
Consult your doctor
Metronidazole Injection should be used with caution in elderly patients. Please consult your doctor before use.
FAQs
Metronidazole Injection belongs to a group of medicines known as antibacterial agents used to treat severe bacterial infections of the bone, skin and skin structure, blood, joint, abdomen, central nervous system, respiratory, and gynaecological systems, meningitis (infection of the membranes that surround the brain and spinal cord), and endocarditis (infection of the heart lining and valves).
Metronidazole Injection suppresses protein synthesis by interacting with DNA, causing helical DNA structure loss and strand breakage. As a result, it induces cell death in susceptible organisms, treating bacterial infections.
Caution should be exercised. Metronidazole Injection may enhance the anticoagulant activity of warfarin and other oral anticoagulants by extending prothrombin time. Inform your doctor if you are taking such medications.
No. Metronidazole Injection is an antibacterial medicine that acts only against bacterial infections, not viral infections like the common cold and flu.
Metronidazole Injection should only be used to treat or prevent infections that have been proven or are strongly suspected to be caused by susceptible anaerobic bacteria.
Extreme caution should be exercised while using Metronidazole Injection in patients with severe liver damage, blood formation disorder, brain, spinal cord or nervous disease. So, let your doctor know if you have any of these conditions.
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Reference
- https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=d46870f5-e2b1-46bd-8413-4a0a8bcf3175&type=display
- https://www.medicines.org.uk/emc/files/pil.13293.pdf
- https://www.medicines.org.uk/emc/product/1842/smpc#gref
- https://www.nhs.uk/medicines/metronidazole/about-metronidazole/
- https://www.drugs.com/drug-interactions/metronidazole-index.html?filter=3
