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  3. Mistabron Respirator Solution 3 ml

Mistabron Respirator Solution 3 ml, Pack of 1 SOLUTION
Mistabron Respirator Solution 3 ml, Pack of 1 SOLUTION
Mistabron Respirator Solution 3 ml, Pack of 1 SOLUTION
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Composition :

MESNA-200MG

Manufacturer/Marketer :

Dr Reddy's Laboratories Ltd

Consume Type :

INHALATION

Return Policy :

Not Returnable

Expires on or after :

About Mistabron Respirator Solution 3 ml

Mistabron Respirator Solution 3 ml belongs to a class of medication known as 'cytoprotectant' primarily used to prevent Hemorrhagic cystitis (a condition that causes bleeding in the urine due to the effect of anticancer agents (Ifosfamide). Our body breaks down the anticancer agent (Ifosfamide) to form a chemical (acrolein) that can harm and irritate the bladder. Mistabron Respirator Solution 3 ml reduces the risk of inflammation and bleeding in the bladder due to other anti-cancer medications. 

Mistabron Respirator Solution 3 ml contains 'Mesna', a chemo-protectant medicine. It works by altering the breakdown of anti-cancer agents (Ifosfamide) found in urine, making it less toxic. In addition, it binds to other urotoxic metabolites and inhibits their effects on the bladder.

Mistabron Respirator Solution 3 ml should be used as advised by your physician. Avoid using more than the recommended dose. The dose of medicine will be advised by your doctor based on your health condition. In some cases, this medicine may cause certain side effects such as nausea, vomiting, headache, flushing (sense of warmth in the face, ears, neck, and trunk), lethargy, rash, diarrhea, light-headedness, abdominal pain, flu-like symptoms and fever. Most of these side effects of Mistabron Respirator Solution 3 ml do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Mistabron Respirator Solution 3 ml is not recommended if you are allergic to it or any of its ingredients. Women of childbearing age should use an effective birth control method to prevent getting pregnant. While utilising Mistabron Respirator Solution 3 ml to track your CBC, your doctor could advise routine urine and blood tests (blood cell count). Because of various underlying clinical disorders, including thrombocytopenia, Mistabron Respirator Solution 3 ml is contraindicated for usage in hematuria. While using Mistabron Respirator Solution 3 ml, it is advisable to consume at least 1-2 litres of liquids every day. Due to significant adverse effects, this medication should not be used in pregnant or nursing women; thus, consult your doctor before beginning treatment with Mistabron Respirator Solution 3 ml.

Uses of Mistabron Respirator Solution 3 ml

Treatment of Ifosfamide-induced hemorrhagic cystitis

Directions for Use

• Mistabron Respirator Solution 3 ml is typically used as prescribed by your doctor to prevent or reduce the side effects of certain chemotherapy drugs.• Mistabron Respirator Solution 3 ml is intended for inhalation or instillation (tracheopulmonary use) only and must not be injected. Before using, carefully read the instruction leaflet. Use the medication exactly as prescribed by your doctor. • Typically, the solution is administered through a nebuliser or inhalation device. Ensure the device is properly set up according to the manufacturer's instructions. After inhalation, rinse your mouth with water to minimise any irritation. • Do not adjust the dosage or frequency without consulting your healthcare provider.

Medicinal Benefits

Mistabron Respirator Solution 3 ml is a member of the 'chemoprotectant' class of drugs, which are principally used to stop urine bleeding caused by the anticancer drug ifosfamide (ifosfamide-induced hemorrhagic cystitis). Additionally, it lessens the chance that anti-cancer medications would induce bladder irritation and bleeding. It includes Mesna, which detoxifies the urotoxic ifosfamide (anti-cancer medication) metabolites by chemically interacting with them. Additionally, it binds to other urotoxic metabolites and prevents their bladder-damaging effects.

How Mistabron Respirator Solution 3 ml Works

Mistabron Respirator Solution 3 ml contains 'Mesna', a chemo-protectant medicine. It works by altering the breakdown of anti-cancer agents (Ifosfamide) found in urine, making it less toxic. In addition, it binds to other urotoxic metabolites and inhibits their effects on the bladder.

Storage

Store in a cool and dry place away from sunlight
Side effects of Mistabron Respirator Solution 3 ml
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Eat a balanced diet high in nutrients and low in sugar.
  • Include fruits, vegetables, and leafy greens rich in vitamins C and K.
  • Brush and floss regularly twice a day with fluoride toothpaste and once a day with floss.
  • Use a soft or extra-soft toothbrush.
  • Reduce stress to minimize inflammation and gum bleeding.
  • Avoid tobacco products as smoking can worsen gum disease.
  • Stay hydrated by drinking water to flush bacteria and food particles.
  • Consider vitamin supplements if deficient to support gum health.
  • Use an antimicrobial mouthwash to reduce bacteria and prevent bleeding.
  • Swish with coconut oil for its antibacterial properties to reduce plaque.
  • Drink green tea rich in catechin to reduce inflammation from oral bacteria.
  • Consult your dentist if gums bleed consistently.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.

What if I have taken an overdose of Mistabron Respirator Solution 3 ml

Do not take more than the prescribed dose. Using more medication will not improve your symptoms; instead, they may cause serious side effects or poisoning. If you suspect that you may have overdosed of Mistabron Respirator Solution 3 ml or observe any side effects, please go to the emergency department of the closest hospital or nursing home. No specific side effects have been reported under these circumstances.

Drug Warnings

Do not use Mistabron Respirator Solution 3 ml if you are allergic to it or any of its ingredients. Mistabron Respirator Solution 3 ml should be used under the supervision of a doctor only. An effective birth control method should be used to avoid pregnancy in women of childbearing age. Maintain a 6-month gap between your last dose of name and your next pregnancy. Regular urine and blood test should be done while using this medicine to monitor your CBC (blood cell count). It is not indicated for use in hematuria due to other underlying pathological conditions like thrombocytopenia. It is important to drink at least 1 litre of fluid daily while using Mistabron Respirator Solution 3 ml. This medicine is known to cause blurry vision and dizziness, so do not drive or operate machinery.

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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Diet & Lifestyle Advise

  • Empty your bladder frequently in the first 24 hours of chemotherapy (cancer treatment). If any pain occurs during urination, let your doctor know it.
  • Nausea can occur as a side effect of chemotherapy. Eat small and frequent meals to avoid it, or you can take any anti-nausea medicine.
  • Sleep at least 8 hours a day and take plenty of rest.
  • Maintain good nutrition. Eat home-cooked and freshly prepared food. Avoid junk, oily and spicy food.

Habit Forming

No

Therapeutic Class

MISCELLANEOUS
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Alcohol

Caution

Consumption of alcohol while using Mistabron Respirator Solution 3 ml may increase the risk of drowsiness. Hence, avoid alcohol intake.

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Pregnancy

Unsafe

Mistabron Respirator Solution 3 ml is not recommended for use in pregnancy as it may harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before using Mistabron Respirator Solution 3 ml. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Unsafe

If you are nursing, you should not use Mistabron Respirator Solution 3 ml since it is known to pass through the breast milk and damage the infant. Keep a week gap between ceasing Mistabron Respirator Solution 3 ml and nursing.

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Driving

Unsafe

Mistabron Respirator Solution 3 ml is known to cause blurred vision and drowsiness. So, do not drive or operate machinery which requires your concentration.

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Liver

Caution

Let your doctor know if you have a history of liver disease before using Mistabron Respirator Solution 3 ml. If necessary, your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Kidney

Caution

Let your doctor know if you have a history of kidney diseases before using Mistabron Respirator Solution 3 ml. If necessary, your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Children

Consult your doctor

Use is not recommended as the safety and efficacy of Mistabron Respirator Solution 3 ml have not been established in children. Moreover, Mistabron Respirator Solution 3 ml contains benzyl alcohol, which is known to cause a gasping syndrome in children.

Have a query?

FAQs

Mistabron Respirator Solution 3 ml is used to treat Ifosfamide-induced hemorrhagic cystitis.

Our body breaks down anticancer agents like ifosfamide or cyclophosphamide to form a chemical known as acrolein, which can harm and irritate the bladder. Mistabron Respirator Solution 3 ml works by making this natural chemical less harmful or toxic. However, Mistabron Respirator Solution 3 ml does not change ifosfamide's anti-cancer effects.

An autoimmune disease is a condition where the immune system targets the body's healthy tissues, leading to discomfort, edema, and damage. Nephritis, systemic lupus erythematosus, and rheumatoid arthritis are a few examples of autoimmune diseases.

No, Mistabron Respirator Solution 3 ml should not be taken along with anti-coagulant like warfarin, heparin or coumarin as it might increase the risk of bleeding and lead to serious complications.

In addition to bladder bleeding in hemorrhagic cystitis, an individual might also experience bladder wall scarring, decreased bladder size (atrophy), severe systemic infection (urosepsis), and urinary obstruction.

Country of origin

India

Manufacturer/Marketer address

504, Peninsula Towers, Peninsula Corporate Park, Ganpatrao Kadam Marg, Lower Parel, IND - Mumbai 400 013
Other Info - MIS0007

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 9:23 AM IST

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Reference

  1. https://www.medindia.net/drug-price/mesna/mistabron-600mg-3ml.htm

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