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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Mofilet-S 360 Tablet is used to prevent organ transplant rejection. It contains Mycophenolate sodium which works by weakening the immune system and preventing it from rejecting the transplanted organ. In some cases, this medicine may cause side effects such as diarrhoea, cough, muscle pain, low blood pressure, fever and respiratory infections. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer :

Emcure Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Mofilet-S 360 Tablet

Mofilet-S 360 Tablet is used to prevent the body from rejecting a transplanted organ such as a kidney, heart or liver. Transplant rejection occurs when the recipient’s immune system identifies the transplanted organ as a ‘foreign object’ and attacks it. If it is not treated promptly, it may cause irreversible damage.

Mofilet-S 360 Tablet contains ‘Mycophenolate sodium’ used in the treatment of organ transplant rejection along with another immunosuppressant and anti-inflammatory agent. It inhibits T and B lymphocytes (white blood cells that attack foreign cells) and suppresses antibodies' production (identify and kill foreign cells). These effects suppress the immune system so that the transplanted graft is not rejected.

Take Mofilet-S 360 Tablet as long as your doctor has prescribed it for you. In some cases, you may experience certain common side effects, such as diarrhoea, cough, muscle pain, low blood pressure, fever and respiratory infections. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually, continue taking Mofilet-S 360 Tablet for as long as your doctor has prescribed. To avoid recurring symptoms, do not stop it midway. Do not take Mofilet-S 360 Tablet if you are pregnant or planning for pregnancy. Mofilet-S 360 Tablet should not be taken by breastfeeding mothers as it passes into breast milk. Mofilet-S 360 Tablet should not be given to children as safety and efficacy have not been established. Mofilet-S 360 Tablet may make you more susceptible to infections, so consult your doctor if you develop fever, sore throat, breathlessness, jaundice, unexplained bleeding, or bruising. Avoid excessive exposure to sunlight, wear protective clothing, and use protective sunscreen with a high protection factor while using Mofilet-S 360 Tablet . Do not contact anyone who has shingles, chickenpox, or measles. Do not take Mofilet-S 360 Tablet if you are not using effective contraception.

Uses of Mofilet-S 360 Tablet

Treatment of Prevent Organ Transplant Rejection.

Directions for Use

Take it as advised by the doctor. Swallow it as a whole with a glass of water. Do not break, crush or chew it.

Medicinal Benefits

Mofilet-S 360 Tablet contains ‘Mycophenolate sodium’, which belongs to the class of ‘immunosuppressants’. It is used to prevent organ transplant rejection. It reduces the activity of the immune system by inhibiting the action of white blood cells (responsible for immune reactions) in the body.

How Mofilet-S 360 Tablet Works

Mofilet-S 360 Tablet contains ‘Mycophenolate sodium’ used in the treatment of organ transplant rejection along with another immunosuppressant and anti-inflammatory agent. It inhibits T and B lymphocytes (white blood cells that attack foreign cells) and suppresses antibodies' production (identify and kill foreign cells). These effects suppress the immune system so that the transplanted graft is not rejected.

Storage

Store in a cool and dry place away from sunlight
Side effects of Mofilet-S 360 Tablet
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in the white blood cells that may lead to impaired immunity.
Managing Medication-Triggered Hypocalcemia (Calcium deficiency or Low Calcium Levels In Blood): A Step-by-Step Guide:
  • Consult Your Doctor: If you experience symptoms such as muscle cramps, tingling, numbness, weakness, or spasms, which may indicate low calcium levels (hypocalcemia), consult your doctor to determine if your medication is the cause.
  • Your doctor will assess your medication regimen and adjust it if necessary to minimize the risk of hypocalcemia.
  • Your doctor may order blood tests to check your calcium levels and monitor for any changes.
  • To manage hypocalcemia, your doctor recommends dietary and lifestyle modifications. This may include increasing your intake of calcium-rich foods to support bone health and calcium levels. If necessary, your doctor may also prescribe calcium and vitamin D supplements to help stabilize your calcium levels.
  • If your condition does not improve or worsens, consult your doctor immediately for further evaluation and treatment.
Managing Medication-Triggered Anxiety: A Comprehensive Approach:
  • Inform your doctor about your anxiety symptoms so that you doctor may explore potential drug interactions and alter your treatment plan.
  • Work with your doctor to adjust your medication regimen or dosage to minimize anxiety symptoms.
  • Reduce anxiety symptoms by practicing relaxation techniques like meditation, deep breathing, or yoga.
  • Regular self-care activities, such as exercise, healthy food, and adequate sleep, can assist control anxiety.
  • Surround yourself with a supportive network of friends, family, or a support group to help manage anxiety and stay motivated.
  • Regularly track anxiety symptoms and report any changes to your doctor to ensure your treatment plan is effective and adjusted as needed.
  • Keep your skin clean by gently washing your face two times daily and after sweating. Choose a mild and non-abrasive cleanser.
  • Use gentle alcohol-free skin care products. Avoid products that might irritate your skin such as exfoliants, astringents and toners.
  • Acne may also occur due to oil in the hair. Thus, if you have oily hair, shampoo more frequently than you do now and keep your hair away from face.
  • Keep your hands off your face as touching face throughout the day might worsen acne. Also, do not pick, squeeze or pop acne as it will prolong the healing process and increase the risk of dark spots and scarring.
  • Avoid tanning by applying a broad spectrum sunscreen and wearing sun-protective clothing when outdoors.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.

What if I have taken an overdose of Mofilet-S 360 Tablet

Take Mofilet-S 360 Tablet only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include nausea, vomiting, stomach pain, diarrhoea, heartburn, and signs of infection (fever, chills, cough, sore throat). If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take Mofilet-S 360 Tablet if you are allergic to any immunosuppressant medicines or mycophenolate sodium. Let your doctor know before using Mofilet-S 360 Tablet if you have liver or kidney problems, severe digestive issues, cancer, liver disease (such as hepatitis B, hepatitis C), current/past infections, rare genetic disorders (such as Lesch-Nyhan or Kelley-Seegmiller syndromes). Do not take Mofilet-S 360 Tablet if you are pregnant or planning for pregnancy as Mofilet-S 360 Tablet is a Pregnancy category risk D medicine which can cause serious congenital disabilities to the unborn baby. Mofilet-S 360 Tablet should not be taken by breastfeeding mothers as it passes into breast milk. Pregnant women should use reliable forms of birth control while on treatment and for six weeks after stopping treatment with Mofilet-S 360 Tablet . While taking Mofilet-S 360 Tablet , do not contact anyone who has shingles, chickenpox, or measles. Mofilet-S 360 Tablet causes dizziness and drowsiness, so drive with caution. Mofilet-S 360 Tablet should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol along with Mofilet-S 360 Tablet as it could lead to increased dizziness. Your doctor may advise you to undergo regular blood tests, kidney and liver tests to monitor your condition. Avoid excessive exposure to sunlight, wear protective clothing, and use protective sunscreen with a high protection factor while using Mofilet-S 360 Tablet .

Drug-Drug Interactions

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Mycophenolic acidColestipol
Critical
Mycophenolic acidNorethisterone
Severe

Drug-Drug Interactions

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Mycophenolic acidColestipol
Critical
How does the drug interact with Mofilet-S 360 Tablet:
Coadministration of Colestipol with Mofilet-S 360 Tablet can reduce its absorption and action in the body. This can lead to low treatment results.

How to manage the interaction:
Taking Mofilet-S 360 Tablet with Colestipol is not recommended as it can result in an interaction, it can be taken if your doctor has advised it.
Mycophenolic acidNorethisterone
Severe
How does the drug interact with Mofilet-S 360 Tablet:
Coadministration of Norethisterone and Mofilet-S 360 Tablet can decrease the levels and effects of Norethisterone.

How to manage the interaction:
There could be a possible interaction between Mofilet-S 360 Tablet and Norethisterone, but they can be taken together if your doctor has prescribed them. However, if you experience hot flashes, vaginal dryness, or abnormal bleeding consult a doctor. Do not discontinue any medications without a doctor's advice.
Mycophenolic acidFerrous sulfate
Severe
How does the drug interact with Mofilet-S 360 Tablet:
Co-administration of Ferrous sulfate with Mofilet-S 360 Tablet decreases levels of Mycophenolate by reducing its absorption.

How to manage the interaction:
There could be a possible interaction between Mofilet-S 360 Tablet and Ferrous sulfate, but they can be taken together if a doctor has prescribed them. However, if you experience upset stomach, nausea, vomiting, diarrhea, constipation sleep problems, fatigue, headache, painful urination, high blood pressure, or swelling of the lower legs, ankles, or feet, joint pain, cough, or shortness of breath consult a doctor. Do not discontinue any medications without a doctor's advice.
Mycophenolic acidColesevelam
Severe
How does the drug interact with Mofilet-S 360 Tablet:
Coadministration of Mofilet-S 360 Tablet and Colesevelam can decrease the levels and effects of Mofilet-S 360 Tablet. This can lead to low treatment outcomes.

How to manage the interaction:
There could be a possible interaction between Mofilet-S 360 Tablet and Colesevelam, but they can be taken together if your doctor has prescribed them. However, if you experience upset stomach, nausea, vomiting, diarrhea, constipation, pain in the stomach area, low blood cell counts, infections, sleep problems, fatigue, headache, painful urination, high blood pressure, or swelling of the lower legs, ankles, consult a doctor. Do not discontinue any medications without a doctor's advice.
Mycophenolic acidDienogest
Severe
How does the drug interact with Mofilet-S 360 Tablet:
Co-administration of Dienogest with Mofilet-S 360 Tablet may decrease the levels and action of Dienogest.

How to manage the interaction:
There could be a possible interaction between Mofilet-S 360 Tablet and Dienogest, but they can be taken together if a doctor has prescribed them. Do not discontinue any medications without a doctor's advice.
Mycophenolic acidNafcillin
Severe
How does the drug interact with Mofilet-S 360 Tablet:
Combine use of Nafcillin and Mofilet-S 360 Tablet may reduce the blood levels and effects of Mofilet-S 360 Tablet.

How to manage the interaction:
There could be a possible interaction between Mofilet-S 360 Tablet and Nafcillin, but they can be taken together if your doctor has prescribed them. However, if you experience upset stomach, nausea, vomiting, diarrhoea, constipation sleep problems, fatigue, headache, painful urination, high blood pressure, or swelling of the lower legs, ankles, or feet, joint pain, cough, or shortness of breath, consult a doctor. Do not discontinue any medications without a doctor's advice.
Mycophenolic acidMedicinal charcoal
Severe
How does the drug interact with Mofilet-S 360 Tablet:
Coadministration of Mofilet-S 360 Tablet and Medicinal charcoal may decrease the levels and effects of Mofilet-S 360 Tablet.

How to manage the interaction:
There could be a possible interaction between Mofilet-S 360 Tablet and charcoal, but they can be taken together if your doctor has prescribed them. However, if you experience any unusual symptoms, consult a doctor. Do not discontinue any medications without a doctor's advice.
Mycophenolic acidDesogestrel
Severe
How does the drug interact with Mofilet-S 360 Tablet:
Coadministration of Mofilet-S 360 Tablet and Desogestrel can decrease the levels and action of Desogestrel.

How to manage the interaction:
Co-administration of Desogestrel with Mofilet-S 360 Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms: abnormal menstruation, dryness of the vagina, or increased hot flushes or if you're looking for other birth control options, consult a doctor. Do not discontinue any medications without consulting a doctor.
Mycophenolic acidAdalimumab
Severe
How does the drug interact with Mofilet-S 360 Tablet:
Taking Mofilet-S 360 Tablet and Adalimumab can lead to or increase the risk or severity of developing serious infections.

How to manage the interaction:
Taking Mofilet-S 360 Tablet and Adalimumab together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms of fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, or burning urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Mycophenolic acidColestyramine
Severe
How does the drug interact with Mofilet-S 360 Tablet:
Coadministration of Mofilet-S 360 Tablet and Colestyramine can decrease the effect of Mofilet-S 360 Tablet.

How to manage the interaction:
There could be a possible interaction between Mofilet-S 360 Tablet and Cholestyramine, it can be taken together if your doctor has prescribed them. However, if you experience fever, diarrhea, sore throat, muscle aches, shortness of breath, inflamed skin, body pain, or burning during urination consult a doctor. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.

  • Performing yoga may also help in improving joint flexibility and pain management.

  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.

  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.

  • Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.

  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listen to soothing music.

  • Acupuncture, massage and physical therapy may also be helpful.

  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.

  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes, and green tea.

Habit Forming

No

Therapeutic Class

IMMUNOSUPPRESSANTS

Mofilet-S 360 Tablet Substitute

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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Mofilet-S 360 Tablet . It could lead to increased dizziness and drowsiness.

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Pregnancy

Unsafe

Mofilet-S 360 Tablet may cause birth defects and miscarriage if taken during pregnancy. Follow contraception advice given by your doctor if you are a woman who could become pregnant. Also, undergo a pregnancy test before starting treatment with Mofilet-S 360 Tablet .

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Breast Feeding

Unsafe

It is not recommended to take Mofilet-S 360 Tablet while you are breastfeeding. Mofilet-S 360 Tablet passes into breast milk.

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Driving

Caution

Mofilet-S 360 Tablet may cause dizziness, tiredness, do not drive or operate heavy machinery if you feel dizzy.

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Liver

Caution

Take Mofilet-S 360 Tablet only after the doctor's prescription, especially if you have liver diseases/conditions as your doctor may adjust the dose as required.

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Kidney

Caution

Please consult your doctor if you have kidney impairment before taking Mofilet-S 360 Tablet as your doctor may adjust the dose as required.

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Children

Unsafe

Mofilet-S 360 Tablet should not be used by children below 18 years of age, as the efficacy and safety have not been established.

FAQs

Mofilet-S 360 Tablet is used to prevent the body from rejecting a transplanted organ such as a kidney, heart or liver.

Mofilet-S 360 Tablet belongs to the group of medications called ‘immunosuppressants’. It works by weakening the immune system by inhibiting the production of cells or antibodies that attack foreign cells. This effect helps in stopping the immune system from targeting and rejecting the transplanted organ.

Mofilet-S 360 Tablet causes leukopenia (decreased number of white blood cells) and hence may make you more susceptible to infections. Consult your doctor if you develop any signs of infections such as fever, sore throat, breathlessness, jaundice, unexplained bleeding or bruising.

Diarrhoea might be a side-effect of Mofilet-S 360 Tablet . Drink lots of fluids and eat food rich in fibre if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience prolonged diarrhoea consult your doctor. Do not take anti-diarrheal medicine on your own.

Mofilet-S 360 Tablet can suppress the immune system and can increase the risk of skin cancer. So, it would be best if you avoid prolonged exposure to sunlight. Also, wear protective clothing covering your head, neck, arms and legs, and use a sunscreen lotion with a high SPF (sun protection factor).

Mofilet-S 360 Tablet can suppress the immune system. You should not donate blood while using Mofilet-S 360 Tablet and at least 60 days after stopping treatment as it makes you more prone to infections. Besides, men should not donate sperm while using Mofilet-S 360 Tablet for at least 90 days after stopping the treatment.

Some medicines might absorb mycophenolate sodium delayed or absorbed fast if taken concomitantly such as antacids containing aluminium or magnesium, colestipol, cholestyramine or calcium-free phosphate binders. Before taking Mofilet-S 360 Tablet , speak with your doctor about your ongoing medication list. Your doctor will decide whether they should be taken along with Mofilet-S 360 Tablet or not.

The live vaccine may not work while on treatment with Mofilet-S 360 Tablet . Do not have immunizations/vaccinations without talking to your doctor first. Also, avoid contact with people who recently had immunizations /vaccinations.

Mofilet-S 360 Tablet may cause side effects such as diarrhoea, cough, muscle pain, low blood pressure, fever and respiratory infections. Talk to your doctor if you experience these side effects persistently.

Mofilet-S 360 Tablet should be swallowed as a whole with water; do not crush or chew it. Mofilet-S 360 Tablet should be taken on an empty stomach (1 hour before or 2 hours after eating or drinking) or as advised by the doctor.

Avoid prolonged or unnecessary exposure to sunlight (sunlamps, tanning beds) and light therapy and wear protective clothing, sunscreen, and sunglasses. This will help lower your risk of developing skin cancer.

Your doctor has prescribed Mofilet-S 360 Tablet to suppress the immunity and prevent the rejection of the transplanted kidney.

Mofilet-S 360 Tablet may increase the risk of skin cancer as it reduces the body’s defences. Limit the amount of sunlight and UV light, wear protective clothing and use sunscreen with high SPF.

Mofilet-S 360 Tablet is not a steroid or chemotherapy medicine. It is an immunosuppressant used to prevent organ rejection after a transplant.

Mofilet-S 360 Tablet may cause skin problems such as hair loss. Talk to the doctor if you have any concerns.

The doctor may recommend regular blood tests to check for signs of infection and blood count. Women of childbearing potential must provide a negative pregnancy test before the start of treatment.

As Mofilet-S 360 Tablet reduces the body’s defences, you may be at a higher risk of developing infections. Therefore, your doctor has asked you to stay away from a person who has chickenpox or shingles.

Mofilet-S 360 Tablet causes a high frequency of miscarriage and birth defects. Therefore, before the start of treatment, women of childbearing potential must provide a negative pregnancy test. Also, women who can become pregnant should use effective contraception during treatment and for 6 months after stopping Mofilet-S 360 Tablet . Two forms of contraception are preferable as this will reduce the risk of unintended pregnancy. Contact the doctor about the effective methods of contraception.

As a precaution, the male or his female partner must use reliable contraception during treatment and for 90 days after stopping Mofilet-S 360 Tablet .

Country of origin

India

Manufacturer/Marketer address

255/2, Hinjawadi, Pune - 411057, India
Other Info - MOF0002

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