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compositionComposition:CANAGLIFLOZIN-300MG
prescription
Prescription Medicine
info
Motivyst 300 Tablet 10's
Motivyst 300 Tablet 10's
Motivyst 300 Tablet 10's
Motivyst 300 Tablet 10's
Motivyst 300 Tablet 10's

Motivyst 300 Tablet is used to treat type 2 diabetes in people whose sugar levels are too high and cannot be controlled by diet and exercise alone. It contains Canagliflozin, which works by inhibiting the reabsorption of glucose in the body, resulting in an increase in glucose excretion through urine. The removal of excessive glucose helps to lower the blood sugar level. Additionally, it also lowers high blood pressure due to increased diuretic effect (water loss) and reduced body weight due to a reduction in glucose availability. In some cases, you may experience urinary tract infections, changes in urination (urinating more frequently or in larger amounts, urgent need to urinate, need to urinate at night), constipation, feeling thirsty, nausea, dizziness, and nausea. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

CANAGLIFLOZIN-300MG

Manufacturer/Marketer :

Johnson & Johnson Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Motivyst 300 Tablet

Motivyst 300 Tablet is an oral prescription medication used to lower blood sugar levels in adults with type 2 diabetes. As a treatment that helps manage glucose levels, its primary medical purpose is to prevent serious complications associated with diabetes. It is also prescribed to reduce the risk of major cardiovascular events like heart attacks and to protect kidney health in certain individuals.

To achieve the best results, you should take Motivyst 300 Tablet consistently once daily, preferably before your first meal of the day. It is taken orally and can be taken with or without food, but taking it before breakfast is highly recommended to manage blood sugar spikes after eating. To maximise its effectiveness, you should combine this treatment with a balanced diet, reduced sugar intake, and a regular exercise routine.

While using Motivyst 300 Tablet , you may experience common side effects like increased urination, mild thirst, or genital yeast infections. While these are usually manageable, you must consult your doctor immediately if you face serious side effects such as severe stomach pain, persistent vomiting, or extreme dizziness, which can point to a serious metabolic issue.

Talk to your doctor before starting this medicine if you have a history of kidney disease, liver damage, low blood pressure, or a history of leg or foot amputations. Do not take this if you have type 1 diabetes, severe kidney failure, are on dialysis, or have had a severe allergic reaction to this medication in the past.

This medication can interact with other drugs like insulin, water pills, or blood pressure medicines, which may increase your risk of low blood sugar or dehydration. It is also important to limit alcohol intake and avoid smoking to protect your cardiovascular and metabolic health while on this treatment. If you are pregnant, breastfeeding, or are an older adult, you should consult your healthcare provider before taking this medicine.

Uses of Motivyst 300 Tablet

Motivyst 300 Tablet is used to treat type 2 diabetes mellitus and reduce cardiovascular risk. The detailed uses of Motivyst 300 Tablet are as follows:

  • Type 2 diabetes mellitus: Motivyst 300 Tablet helps lower blood sugar levels in adults by helping the kidneys remove excess sugar through urine.
  • Heart disease risk reduction: It helps decrease the risk of major cardiovascular events, such as heart attacks, strokes, or death, in adults who have both type 2 diabetes and established heart conditions.
  • Diabetic kidney disease: It helps slow the progression of kidney damage and reduces the risk of hospitalisation for heart failure in adults with type 2 diabetes.

Key Benefits

Motivyst 300 Tablet helps manage blood sugar levels while providing additional protection for the heart and kidneys. By improving glucose control and supporting the health of vital organs, it contributes to better overall wellbeing and may help reduce the risk of long-term diabetes-related complications.

  • Helps Control Blood Sugar Levels: By reducing rises in blood sugar after meals, Motivyst 300 Tablet helps maintain more stable glucose levels throughout the day. This supports effective diabetes management and may help lower the risk of complications associated with uncontrolled blood sugar.
  • Supports Heart Health: Motivyst 300 Tablet helps reduce the risk of hospitalisation due to heart failure and supports better cardiovascular health. This may contribute to improved stamina, reduced shortness of breath, and greater comfort during everyday activities.
  • Helps Protect Kidney Function: In addition to managing blood sugar, Motivyst 300 Tablet supports kidney health and may help slow the progression of diabetes-related kidney damage, promoting better long-term kidney function and overall health outcomes.
Side effects of Motivyst 300 Tablet
  • Inflammation of Vagina needs immediate attention and cannot be ignored.
  • Get a physical examination and prevent wearing clothes that can hold heat and moisture.
  • Avoid using vaginal sprays or perfumed soaps that increase itching and irritation.
  • Follow your doctor's instructions, and rest well with proper medication.
  • Take a balanced diet and get regular screenings to reduce inflammation.
  • If you experience low blood sugar levels, inform your doctor. They will assess the severity and make recommendations for the next actions.
  • Your doctor will assess your symptoms, blood sugar levels, and overall health before recommending the best course of action, which may include treatment, lifestyle modifications, or prescription adjustments.
  • Follow your doctor's instructions carefully to manage the episode and adjust your treatment plan.
  • Make medication adjustments as recommended by your doctor to prevent future episodes.
  • Implement diet and lifestyle modifications as your doctor advises to manage low blood sugar levels.
  • Monitor your blood sugar levels closely for patterns and changes.
  • Track your progress by recording your blood sugar levels, food intake, and physical activity.
  • Seek further guidance from your doctor if symptoms persist or worsen so that your treatment plan can be revised.
  • Talk to your healthcare professional and explain the symptoms you are experiencing and get appropriate medications.
  • Avoid products that irritate the vulva, such as perfumed soaps, detergents, and feminine products.
  • Wear loose-fitting, breathable cotton underwear.
  • Change into clean, dry clothes after exercising or swimming.
  • Use mild, unscented soaps and warm water to clean the genitals.
  • Use ointments recommended to reduce irritation and itchiness.
  • Take sitz baths in warm water without soap.
  • Use cold compresses or topical numbing agents to relieve itching, burning, or discomfort.
  • Seek medical advice immediately if you're experiencing new, unusual, or severe symptoms.
  • Limit fruit intake to two servings a day, choose a low-potassium options like apples and strawberries.
  • Restrict starchy vegetables like potatoes and pumpkin to half a cup daily.
  • Avoid or limit foods like tomato products, high-bran cereals, and salty or sugary snacks.
  • Limit dairy products to 200g of yoghurt or 300ml of milk per day.
Managing Medication-Triggered Moniliasis (a yeast infection): A Step-by-Step Guide:
  • If you experience symptoms like itching, burning, redness, or discharge after taking medication, consult your doctor immediately and share your symptoms, medication regimen, and medical history.
  • Your doctor will assess your medication regimen to determine if it's contributing to the moniliasis and identify the best course of action to manage your condition.
  • Your doctor may prescribe antifungal medications or recommend other treatments to help clear up the infection. They may also suggest self-care measures to help manage symptoms and prevent future infections.
  • If your condition doesn't improve or persists, consult your doctor and report it. Your doctor will assess your progress, adjust your treatment plan, and provide advice to ensure the best outcome.
  • Stay hydrated by drinking plenty of water to help eliminate toxins.
  • Incorporate probiotic-rich foods like yogurt or kefir into your diet to support gut health.
  • Maintain good genital hygiene and keep the area clean and dry.
  • Refrain from intercourse until your treatment is complete.
  • Wear breathable, cotton underwear to minimize moisture buildup.
  • Apply coconut oil or diluted tea tree oil to the affected area for antifungal benefits.
  • Consider using probiotic suppositories to promote vaginal health.
  • Consult a healthcare provider if you suspect a vaginal infection.
  • Finish taking all prescribed medication as directed by your healthcare provider to get optimal treatment results.
  • Attend follow-up appointments to confirm the infection has cleared.

Directions for Use

  • Motivyst 300 Tablet can be taken with or without food, but it is best to take it before the first meal of the day.
  • It is usually taken once daily or as prescribed by your doctor.
  • Swallow Motivyst 300 Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Motivyst 300 Tablet Works

Motivyst 300 Tablet contains canagliflozin. This medication works in a unique way that does not rely entirely on your body's insulin. Under normal conditions, the kidneys filter glucose and then reabsorb much of it back into the bloodstream through a protein called sodium-glucose co-transporter 2 (SGLT2). Canagliflozin works by blocking SGLT2 in the kidney tubules, reducing the reabsorption of glucose. As a result, excess glucose is removed from the body through the urine, helping lower blood sugar levels independently of insulin. This unique pathway helps lower your blood sugar levels independently of insulin, providing a steady and reliable way to manage diabetes.
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Alcohol

Unsafe

You should avoid consuming alcohol with Motivyst 300 Tablet as it may alter your blood sugar levels or lead to serious side effects.

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Pregnancy

Consult your doctor

Motivyst 300 Tablet is not recommended during pregnancy. However, your doctor may prescribe it for you during pregnancy if he/she feels the benefit outweighs the risk. You should not take Motivyst 300 Tablet without a doctor's advice.

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Breast Feeding

Consult your doctor

There is no sufficient data on how Motivyst 300 Tablet affects breastfeeding. It is safe to seek medical advice before you start Motivyst 300 Tablet if you are breastfeeding.

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Driving

Caution

Motivyst 300 Tablet should not affect your ability to drive or operate machinery/tools.

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Liver

Caution

Motivyst 300 Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Motivyst 300 Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor depending on your renal functions. Motivyst 300 Tablet is not recommended in severe kidney disease. Regular monitoring of kidney function tests is therefore important if you're taking Motivyst 300 Tablet .

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Children

Caution

Motivyst 300 Tablet is not recommended for children below 18 years of age, as the safety and effectiveness were not established.

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Heart

Consult your doctor

Motivyst 300 Tablet is not contraindicated in heart patients. It is often prescribed to reduce the risk of cardiovascular death and hospitalisation for heart failure in adults with type 2 diabetes and established cardiovascular disease.

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Geriatrics

Consult your doctor

While Motivyst 300 Tablet is safe to be taken by older patients, it is critical to exercise caution and monitor for potential adverse effects, such as dehydration, low blood pressure, and urinary tract infections, which are more common in older adults. Before starting dapagliflozin, it is recommended that you consult with a doctor, particularly if you are 75 or older.

What if I have taken an overdose of Motivyst 300 Tablet

If you suspect an overdose or experience severe symptoms after taking too much of this medication, seek immediate medical attention or contact a poison control centre right away.

Diet & Lifestyle Advise

  • Drink plenty of water throughout the day to stay well-hydrated, as this medicine naturally increases fluid loss through urination.
  • Follow a balanced meal plan focusing on vegetables, lean proteins, and fibre-rich carbohydrates to help maintain stable blood sugar levels.
  • Engage in regular physical activity, such as walking, swimming, or cycling, as recommended by your doctor to help your body use insulin more effectively.
  • Take extra care of your feet by checking them daily for cuts, sores, or redness, and wear comfortable, protective footwear.

Have a query?

How Soon It Starts Working

The time required for Motivyst 300 Tablet to start to work: Motivyst 300 Tablet ideally shows its action within 1 to 2 hoursafter administration. The time for which the effects of Motivyst 300 Tablet last: The effect of Motivyst 300 Tablet lasts for 24 hours.

What if you forget to take Motivyst 300 Tablet

If you miss a dose, take it as soon as you remember on that day. If you do not remember until the next day, skip the missed dose and resume your regular daily schedule. Do not take two doses at the same time to make up for a missed one.

Storage

•Store Motivyst 300 Tablet tablets at room temperature, safely between 20°C and 25°C (68°F to 77°F). •Keep the tablets in their original packaging to protect them from light and moisture.

Drug Warnings

  • Monitor your fluid intake carefully, especially during hot weather or physical exercise, to avoid severe dehydration.
  • Check your blood sugar levels regularly as directed by your healthcare team, especially during periods of stress, illness, or changes in your diet.
  • Pay close attention to genital hygiene to help reduce the risk of yeast or urinary tract infections.
  • Inform your surgeon or dentist that you are taking this medication well in advance of any scheduled surgeries, as you may need to pause treatment.
  • Always keep a quick source of sugar, like fruit juice or glucose tablets, nearby in case you experience sudden low blood sugar.
  • Do not take Motivyst 300 Tablet unless specifically advised by your healthcare provider if you have type 1 diabetes, severe kidney failure or are receiving dialysis or had a serious allergic reaction to canagliflozin or any of its ingredients or are in the second or third trimester of pregnancy, unless your doctor determines otherwise
  • Canagliflozin has been associated with an increased risk of lower-limb amputations, particularly involving the toes, feet, or legs. Inform your doctor if you have a history of amputation, peripheral vascular disease, diabetic foot ulcers, or neuropathy. Seek medical attention promptly if you develop new foot pain, sores, ulcers, tenderness, infection, or changes in skin colour. 

Drug-Drug Interactions

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Drug-Drug Interactions

  • Diuretics (water pills): Taking these alongside Motivyst 300 Tablet can significantly increase your risk of dehydration and low blood pressure.
  • Insulin or sulfonylureas: Combining these medications with Motivyst 300 Tablet may lower your blood sugar too much, increasing the risk of hypoglycaemia.

Drug-Food Interactions

  • Taking this medication before your first meal of the day is recommended to help control the rise in blood sugar that occurs after eating.

Drug-Disease Interactions

  • Severe kidney disease: This medicine is not effective and should not be used if you have severe kidney failure or are on dialysis.
  • Low blood pressure (hypotension): This medication can lower blood pressure further due to increased fluid loss.
  • History of diabetic ketoacidosis: Individuals with a history of this serious condition may have an increased risk of developing it again.
CanagliflozinGatifloxacin
Critical
CanagliflozinMorphine
Severe

Drug-Drug Interactions

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CanagliflozinGatifloxacin
Critical
How does the drug interact with Motivyst 300 Tablet:
Co-administration of Motivyst 300 Tablet with Gatifloxacin may affect blood glucose levels. Both low blood glucose and, less frequently, high blood glucose have been reported.

How to manage the interaction:
Although there is a possible interaction, Motivyst 300 Tablet can be taken with Gatifloxacin if prescribed by the doctor. Consult the prescriber if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not discontinue the medication without consulting a doctor.
CanagliflozinMorphine
Severe
How does the drug interact with Motivyst 300 Tablet:
Co-administration of Morphine with Motivyst 300 Tablet may increase the blood levels and side effects of morphine.

How to manage the interaction:
Co-administration of Morphine with Motivyst 300 Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like trouble breathing, feeling tired, or having a cough, dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination, make sure to contact a doctor immediately. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

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CANAGLIFLOZIN-300MGHerbal products/medicines
Moderate

Drug-Food Interactions

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CANAGLIFLOZIN-300MGHerbal products/medicines
Moderate
Common Foods to Avoid:
St. John’S Wort

How to manage the interaction:
Concomitant use of Motivyst 300 Tablet with St. John's Wort may decrease the serum concentration of Motivyst 300 Tablet. Consult the prescriber, the doctor may adjust the dose of Motivyst 300 Tablet if you are taking St.John's wort.

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FAQs

Motivyst 300 Tablet is used to treat type 2 diabetes, also called 'non-insulin-dependent diabetes.
Motivyst 300 Tablet is a type of medicine known as a sodium-glucose cotransporter-2 (SGLT2) inhibitor used for the treatment of type -2 diabetes. It lowers blood sugar levels by blocking the action of SGLT-2 in the kidney and removing excess sugar from your body through urination.
Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule.
Do not stop taking Motivyst 300 Tablet until your prescribed course is finished, even if you feel better.
Once blood sugar goes below the normal range (70mg/dl), it is called hypoglycemia or low blood sugar. If you feel your sugar level is going down and feel weak, immediately eat sugar candies. It will help to balance the blood sugar level in your body. So, it is advisable to keep sugar candies with you if you have diabetes.
Type 2 diabetes mellitus is a chronic (long-lasting) condition that keeps the body away from properly utilizing insulin. Hence, people affected with type 2 diabetes either do not produce enough insulin, or there is resistance to the action of insulin. Middle-aged or older are most likely to suffer from type 2 diabetes, so it is also known as adult-onset diabetes. The symptoms include frequent urination at night, increased thirst, slow wound healing, increased hunger, fatigue, and blurred vision.
During the treatment with Motivyst 300 Tablet , maintain a healthy diet and do regular exercise to control blood sugar levels. Avoid skipping any dose of Motivyst 300 Tablet , as it may cause fluctuations in your blood sugar levels. Tell your doctor about all of your medical conditions and any other medications that you are taking.
No, Invokana tablet and metformin are not the same. Though, both the medicines are used to treat Type 2 diabetes mellitus, their mechanisms of action are different.
Take Motivyst 300 Tablet with or without food as prescribed by your doctor. Try to take it at the same time every day. Swallow it as whole with a glass of water. Do not crush, break or chew it.
Record your blood sugar levels, either daily or on a regular basis so that you can show them to your doctor on your next visit. Your doctor will examine these reports and let you know whether Motivyst 300 Tablet is working or not.
Patients with a history of amputation are more prone to lower limb amputation. Patients with foot ulcers or sores, as well as those who have or had heart disease, are also at high risk. Additionally, patients who have or have suffered from neuropathy (nerve damage that causes numbness, tingling, and pain, usually in your hands and feet) and peripheral vascular disease (narrowing of blood vessels in feet, legs, or arms causing numbness, pain, or coldness) are also at high risk of lower limb amputation.
Motivyst 300 Tablet usually causes loss of fat mass which typically results in weight loss. However, this may differ from person to person depending upon the doses and whether it is being used alone or with other diabetes medications.
The serious side effects of Motivyst 300 Tablet are sudden kidney impairment, ketoacidosis (increased ketones in your blood or urine), low blood sugar, some allergic reaction, and serious urinary tract infections. Although it is rare, Motivyst 300 Tablet may also cause a severe bacterial infection that may damage the tissue beneath the skin in the perineum (area between and around the anus and genitals). Motivyst 300 Tablet may weaken your bones, increasing the risk of fractures, especially in the wrists, upper arms, or hands.
No, Motivyst 300 Tablet is only approved to treat type 2 diabetes and should not be used by individuals with type 1 diabetes. Talk to your doctor.
It is best to avoid or limit alcohol, as it can increase your risk of dehydration and a dangerous medical condition called diabetic ketoacidosis. Talk to your doctor.
Because this medication increases sugar in your urine, genital yeast infections can occur. Mild cases can often be treated easily, but you should seek guidance on how to manage them. Talk to your doctor.
Yes, you may need to temporarily stop taking this medication several days before a scheduled surgery to lower the risk of ketoacidosis. Talk to your doctor.
This medication is generally not recommended during the second and third trimesters of pregnancy because it may affect the developing kidneys of the unborn child. Talk to your doctor.
Canagliflozin works in the kidney tubules by blocking the SGLT2 transporter, which helps remove excess glucose through the urine. Because its effectiveness depends on adequate kidney function, your doctor will check your kidney function using tests such as eGFR before starting treatment and during follow-up visits. Dose adjustments or treatment restrictions may be necessary if kidney function declines. Talk to your doctor.

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While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

Italy

Manufacturer/Marketer address

Johnson & Johnson Private Limited., 501 Arena Space, Behind Majas Bus Depot, Off Jogeshwari Vikhroli Link Road, Jogeshwari (E), Mumbai 400 060
Other Info - MOT0070

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