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  3. Multaq 400Mg Tablet

Multaq 400Mg Tablet, Pack of 10 TabletS
Multaq 400Mg Tablet, Pack of 10 TabletS
Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Multaq 400Mg Tablet is used to treat arrhythmia (irregular heartbeat). It contains Dronedarone which works by blocking abnormal electrical signals in the heart and restoring normal heart rhythm. In some cases, this medicine may cause side effects such as slow heartbeat, diarrhoea, nausea and vomiting. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

DRONEDARONE-400MG

Manufacturer/Marketer :

Aventis Pharma

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Multaq 400Mg Tablet

Multaq 400Mg Tablet belongs to a group of medications known as 'anti-arrhythmic' primarily used to treat arrhythmia (irregular heartbeat) in patients with paroxysmal (sudden attack) or persistent atrial fibrillation (irregular heartbeat due to poor blood flow). Besides this, Multaq 400Mg Tablet is also used to treat 'cardioversion' which is a medical procedure that changes the abnormal heartbeat to a normal rhythm. Arrhythmia is a problem associated with the rate of rhythm at which the heartbeats.

Multaq 400Mg Tablet contains 'Dronedarone' a Class III anti-arrhythmic drug that restores normal heart rhythm and reduces heart rate in atrial fibrillation. Multaq 400Mg Tablet blocks abnormal electrical signals in the heart. Also, it prevents ventricular fibrillation (a rapid contraction of heart muscle) and ventricular tachycardia (lower chambers of the heart ventricles that beat quickly than normal).

Take Multaq 400Mg Tablet as prescribed by your doctor. Your dose and duration of Multaq 400Mg Tablet will be advised by your doctor, depending upon your medical condition. In some cases, you may experience slow heartbeat, diarrhoea, nausea and vomiting. Most of these side effects of Multaq 400Mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.  

Please inform your doctor if you are using any prescription, non-prescription drugs, including vitamins and herbal products. Let your doctor know if you have any allergic reactions to Multaq 400Mg Tablet or any other medicines, before starting Multaq 400Mg Tablet. Inform your doctor if you have heart, kidney or liver problems and electrolyte imbalance. It is advised to consult a doctor if you are a pregnant or breastfeeding mother. Multaq 400Mg Tablet is not recommended for use during pregnancy. Do not stop taking Multaq 400Mg Tablet without consulting your doctor since it may worsen your condition and increase the risk of future heart problems. 

Uses of Multaq 400Mg Tablet

Treatment of Arrhythmia (irregular heartbeat).

Directions for Use

Tablet: Take it with or without food at regular intervals, as prescribed by the doctor. Do not crush, chew or break it.

Medicinal Benefits

Multaq 400Mg Tablet contains Dronedarone, a class III anti-arrhythmic drug. It treats arrhythmia (irregular heartbeat) in patients with paroxysmal (sudden attack) or persistent atrial fibrillation (irregular heartbeat due to poor blood flow). It blocks abnormal electrical signals in the heart and works by restoring normal heart rhythm. It also prevents ventricular fibrillation (a rapid contraction of heart muscle) and ventricular tachycardia (lower chambers of the heart (ventricles) beat quickly than normal). Multaq 400Mg Tablet is used in cardioversion, a medical procedure that changes the abnormal heartbeat to a normal rhythm.

How Multaq 400Mg Tablet Works

Multaq 400Mg Tablet contains 'Dronedarone' a Class III anti-arrhythmic drug that restores normal heart rhythm and reduces heart rate in atrial fibrillation. Multaq 400Mg Tablet blocks abnormal electrical signals in the heart. Also, it prevents ventricular fibrillation (a rapid contraction of heart muscle) and ventricular tachycardia (lower chambers of the heart ventricles that beat quickly than normal).

Storage

Store in a cool and dry place away from sunlight
Side effects of Multaq 400Mg Tablet
  • Heart failure needs immediate medical attention. To manage this effect, the doctor's instructions must be followed strictly.
  • Take care of change in your weight as there can be sudden changes.
  • Rest and refrain from physical activity, and restart after a few days.
  • Reduce your salt intake and control your diet with the help of a dietician.
  • Track your symptoms and keep your follow-up appointments to manage severe side effects.
  • Increased creatinine levels must be corrected immediately with the help of a doctor.
  • Reduce strenuous activities that can lead to muscle breakdown and production of creatinine.
  • Sleep for 7-8 hours per night to assist your body in repairing and rebuilding tissue.
  • Manage your blood pressure by implementing changes in lifestyle like losing weight, reducing stress and exercising regularly.
  • Avoid smoking and drinking alcohol.
  • Exercising regularly helps lower the risk of heart problems.
  • Maintain a healthy diet, including vegetables and fruits.
  • Rest well; get enough sleep.
  • Manage stress with yoga and meditation.
  • Limit alcohol and smoking.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

What if I have taken an overdose of Multaq 400Mg Tablet

Avoid exceeding the recommended dose as it might cause an overdose. Seek immediate medical attention if you experience any unusual symptoms.

Drug Warnings

Brief your medical history to the doctor if you have any heart problems liver, kidney diseases and electrolyte imbalance (low potassium and magnesium) before starting Multaq 400Mg Tablet. Multaq 400Mg Tablet may affect QT prolongation (heart muscle takes longer than usual to recharge between beats) that can cause serious fast/irregular heartbeat. Hence it is advised to inform your doctor if you have heart-related problems like heart failure, slow heartbeat and a family history of heart diseases. Multaq 400Mg Tablet is contraindicated during pregnancy since it has harmful effects on the foetus. Consult your doctor before using Multaq 400Mg Tablet if you are a breastfeeding mother. Do not drive or operate machinery if you experience any side effects that affect your ability to concentrate and drive. Avoid consumption of alcohol with Multaq 400Mg Tablet as it may decrease the efficacy of Multaq 400Mg Tablet. Multaq 400Mg Tablet is not recommended in patients younger than 18 years of age.

Drug-Drug Interactions

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DronedaronePrimaquine
Critical
DronedaroneAlfuzosin
Critical

Drug-Drug Interactions

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DronedaronePrimaquine
Critical
How does the drug interact with Multaq 400Mg Tablet:
When Primaquine is taken with Multaq 400Mg Tablet, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Primaquine with Multaq 400Mg Tablet is not advised generally as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
DronedaroneAlfuzosin
Critical
How does the drug interact with Multaq 400Mg Tablet:
Coadministration of Multaq 400Mg Tablet with Alfuzosin can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Multaq 400Mg Tablet with Alfuzosin together is not recommended, as it leads to an interaction, it can be taken if your doctor has advised it. However, if you experience dizziness, shortness of breath, chest discomfort, or palpitations, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
DronedaroneClarithromycin
Critical
How does the drug interact with Multaq 400Mg Tablet:
When Multaq 400Mg Tablet is taken with Clarithromycin, can increase the blood levels of Multaq 400Mg Tablet and cause an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Clarithromycin with Multaq 400Mg Tablet can result in an interaction, it should be taken only if a doctor has advised it. However, if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitation, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DronedaroneMoxifloxacin
Critical
How does the drug interact with Multaq 400Mg Tablet:
Using Multaq 400Mg Tablet together with Moxifloxacin can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Moxifloxacin with Multaq 400Mg Tablet is not recommended as it can lead to an interaction; it can be taken if advised by your doctor. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations.
DronedaroneChlorpromazine
Critical
How does the drug interact with Multaq 400Mg Tablet:
Taking Chlorpromazine with Multaq 400Mg Tablet can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Chlorpromazine with Multaq 400Mg Tablet is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
DronedaroneGranisetron
Critical
How does the drug interact with Multaq 400Mg Tablet:
Taking Granisetron with Multaq 400Mg Tablet can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Granisetron with Multaq 400Mg Tablet is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
DronedaroneHaloperidol
Critical
How does the drug interact with Multaq 400Mg Tablet:
Coadministration of Multaq 400Mg Tablet and Haloperidol can increase the risk or severity of irregular heart rhythms which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Multaq 400Mg Tablet and Haloperidol together is generally avoided as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
DronedaroneClomipramine
Critical
How does the drug interact with Multaq 400Mg Tablet:
When Clomipramine is taken with Multaq 400Mg Tablet, can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
There may be a possibility of interaction between Clomipramine and Multaq 400Mg Tablet, but it can be taken if prescribed by a doctor. If you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.
DronedaroneTizanidine
Critical
How does the drug interact with Multaq 400Mg Tablet:
Coadministration of Tizanidine with Multaq 400Mg Tablet can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Tizanidine with Multaq 400Mg Tablet is generally avoided as it can result in an interaction, it can be taken when prescribed by a doctor. If you experience sudden dizziness, shortness of breath, palpitations, or chest pain, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
DronedaroneHydroxyzine
Critical
How does the drug interact with Multaq 400Mg Tablet:
Taking Multaq 400Mg Tablet with Hydroxyzine can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Hydroxyzine with Multaq 400Mg Tablet is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Keep your weight under control with BMI 19.5-24.9.
  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.
  • Limit sodium chloride intake (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.
  • If you are taking alcohol, then only one serving for women and two servings for men is advisable.
  • Quitting smoking is the best strategy to lower the risk of heart disease.
  • Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress and practice mindfulness techniques.
  • Try to include heart-healthy omega 3 fatty acid containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil and coconut oil to lower your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTIARRHYTHMICS

Multaq 400Mg Tablet Substitute

Substitutes safety advice

  • Dilsave 400 mg Tablet 10's

    by Others

    ₹62.10per tablet

Product Substitutes

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Alcohol

Caution

It is advised to limit alcohol intake when you are being treated with Multaq 400Mg Tablet.

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Pregnancy

Unsafe

Multaq 400Mg Tablet is a pregnancy category X drug, so it is not recommended and unsafe in pregnancy. It can affect and harm the developing baby. Please seek medical advice for more information.

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Breast Feeding

Caution

It is not known if Multaq 400Mg Tablet is excreted into the breast milk. Due to possible effects on the breastfed infant, Multaq 400Mg Tablet is not recommended for use if you are a nursing mother. Please consult your doctor for more information before taking Multaq 400Mg Tablet.

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Driving

Caution

Multaq 400Mg Tablet is possibly safe and does not affect your ability to drive. However, if you experience any symptoms that may affect your mental focus and ability to drive, do not drive or operate machinery until you feel better.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before taking Multaq 400Mg Tablet. Your doctor will weigh the benefits and any potential risks before prescribing Multaq 400Mg Tablet.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases before taking Multaq 400Mg Tablet. Your doctor will weigh the benefits and any potential risks before prescribing Multaq 400Mg Tablet.

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Children

Unsafe

Safety and effectiveness of Multaq 400Mg Tablet have not been established in patients below 18 years of age.

Have a query?

FAQs

Multaq 400Mg Tablet is used to treat arrhythmia (irregular heartbeat) in patients with paroxysmal (sudden attack) or persistent atrial fibrillation (irregular heartbeat due to poor blood flow).

Multaq 400Mg Tablet contains Dronedarone that works as an antiarrhythmic by blocking abnormal electrical signals in the heart. Thus Multaq 400Mg Tablet helps to treat the uneven heartbeats and helps in normalising the heart rhythm.

Do not stop using Multaq 400Mg Tablet even if you feel better. It should be strictly used as advised by your doctor to avoid the recurrence of symptoms like irregular heartbeat and worsening of the disease.

Multaq 400Mg Tablet should be used with caution in cases of any allergic reactions, heart problems like heart failure, slow heartbeat, QT prolongation (heart muscle takes longer than usual to recharge between beats) in the ECG (electrocardiogram), liver, kidney diseases and electrolyte imbalance (low levels of potassium and magnesium).

Store Multaq 400Mg Tablet away from direct sunlight and at a temperature not exceeding 30°C. Keep this medicine out of sight and reach of children.

If you missed a dose, take Multaq 400Mg Tablet as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule. Do not double the dose.

Multaq 400Mg Tablet is used to treat arrhythmia (irregular heartbeat) in patients with paroxysmal (sudden onset) or persistent atrial fibrillation (irregular heartbeat caused by poor blood flow). Additionally, it is used in ‘cardioversion,' a medical procedure that restores an abnormal heartbeat to a normal rhythm.

Yes, Multaq 400Mg Tablet is safe if taken in dose and duration exactly as prescribed by the doctor.

Warning signals of liver toxicity caused by Multaq 400Mg Tablet may include dark urine, yellowing of the skin or eyes (jaundice), light-coloured stools, loss of appetite, nausea, vomiting, unusual tiredness, and pain in the upper right side of the abdomen. If you notice any of these symptoms, consult the doctor immediately.

Multaq 400Mg Tablet may cause optic neuropathy, the symptoms of optic neuropathy may include blurred vision, sudden vision loss, loss of peripheral vision, difficulty seeing in low light, and pain when moving the eye. If you experience any of these symptoms, consult the doctor immediately.

Multaq 400Mg Tablet should be taken orally with or without food at regular intervals. Swallow it as a whole with a glass of water. Do not chew, crush or break it.

The side effects of Multaq 400Mg Tablet include diarrhoea, slow heartbeat, nausea and vomiting. Consult the doctor if any of these side effects persist or worsen.

Country of origin

India

Manufacturer/Marketer address

Behind HDFC Bank, Sai Nagar, Devendra Nagar Road, Raipur, Chhattisgarh (492001) - India
Other Info - MUL0153

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jan 1, 2025 | 2:48 PM IST

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Reference

  1. https://www.webmd.com/drugs/2/drug-152652/dronedarone-oral/details
  2. https://www.medicines.org.uk/emc/files/pil.10924.pdf
  3. https://www.drugs.com/pregnancy/dronedarone.html
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