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  3. Nflox-B 400 mg Tablet 10's

Prescription drug
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Nflox-B 400 mg Tablet 10's, Pack of 10 TabletS
Nflox-B 400 mg Tablet 10's, Pack of 10 TabletS
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Synonym :

BETA CYCLODEXTRAN+NORFLOXACIN

Composition :

BETADEX-10MG + NORFLOXACIN-400MG

Manufacturer/Marketer :

Laborate Pharmaceuticals India Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Nflox-B 400 mg Tablet

Nflox-B 400 mg Tablet is a combination medication used to treat bacterial infections, including urinary tract infections, prostatitis (inflammation of the prostate), and gonorrhea (a sexually transmitted infection). A bacterial infection occurs when harmful bacteria enter the body, multiply, and cause harm to tissues or organs, leading to symptoms like pain, fever, and inflammation.

Nflox-B 400 mg Tablet  contains Betadex (Beta-Cyclodextrin) and Norfloxacin. Beta-cyclodextrin increases the effectiveness of norfloxacin by improving its solubility, allowing it to be absorbed more quickly into the bloodstream and reach adequate levels in the body. Norfloxacin is a fluoroquinolone antibiotic that kills bacteria by inhibiting DNA synthesis.

Take Nflox-B 400 mg Tablet for the duration your doctor prescribes, based on your medical condition. Some common side effects may include abdominal cramps, nausea, headache, diarrhea, and dizziness. These effects are usually temporary and do not require medical attention. However, if they continue or worsen, see your doctor for advice.

Inform your doctor before using Nflox-B 400 mg Tablet if you have a history of heart, liver, or kidney disease. Avoid taking this medication during pregnancy or breastfeeding unless prescribed by your doctor. Keep your doctor updated on your medications and health condition to prevent potential side effects.

Uses of Nflox-B 400 mg Tablet

Nflox-B 400 mg Tablet is used in the treatment of bacterial infections. The detailed uses of Nflox-B 400 mg Tablet are as follows:

  • Treatment of bacterial infections: Nflox-B 400 mg Tablet is used for treating bacterial infections.
  • Effective against infections: Nflox-B 400 mg Tablet is effective against urinary tract infections, prostatitis, and sexually transmitted infections.

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Side effects of Nflox-B 400 mg Tablet
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Directions for Use

  • Nflox-B 400 mg Tablet can be taken with or without food or as advised by your doctor.
  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Swallow it as a whole with a glass of water.
  • Do not break, chew or crush Nflox-B 400 mg Tablet .

Key Benefits

Nflox-B 400 mg Tablet belongs to a group of medicines called quinolone antibiotics, used to treat bacterial infections, including urinary tract infections, prostatitis, and gonorrhea. It is a combination of beta-cyclodextrin and norfloxacin. Beta-cyclodextrin enhances the effectiveness of Norfloxacin. Norfloxacin is a fluoroquinolone antibiotic that kills bacteria by inhibiting DNA synthesis. Together, they provide a potent treatment for many bacterial infections, ensuring better absorption and increased antibacterial action.

How Nflox-B 400 mg Tablet Works

Nflox-B 400 mg Tablet includes Beta-Cyclodextrin and Norfloxacin. The presence of beta-cyclodextrin improves the potency of norfloxacin. Norfloxacin works by blocking the production of the DNA gyrase enzyme, which leads to bacterial death and helps treat infections. Nflox-B 400 mg Tablet exhibits a wide range of antibacterial effects against both gram-positive and gram-negative aerobic bacteria.

Storage

• Store in a cool and dry place away from sunlight.• Keep Nflox-B 400 mg Tablet out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Nflox-B 400 mg Tablet

Take Nflox-B 400 mg Tablet only as advised by the physician. Do not exceed the prescribed dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take Nflox-B 400 mg Tablet if you are allergic to any of its ingredients or if you have experienced tendon swelling or rupture while using quinolone antibiotics. Seek medical attention immediately if you experience pain, swelling, or inflammation in your tendons while using Nflox-B 400 mg Tablet . Inform your doctor if you have epilepsy, low potassium levels, muscle or nerve disorders, a head injury or brain tumor, diabetes, rheumatoid arthritis, or heart, kidney, or liver conditions. Discuss with your doctor if you are pregnant or breastfeeding. Limit alcohol intake while using Nflox-B 400 mg Tablet , as it may increase dizziness. Nflox-B 400 mg Tablet can cause dizziness and vision disturbances, so exercise caution when driving or operating machinery.

 

Drug-Drug Interactions

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NorfloxacinAmiodarone
Critical
NorfloxacinCisapride
Critical

Drug-Drug Interactions

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NorfloxacinAmiodarone
Critical
How does the drug interact with Nflox-B 400 mg Tablet:
The combination of Amiodarone and Nflox-B 400 mg Tablet may significantly raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Despite the fact that Amiodarone and Nflox-B 400 mg Tablet interact, it can be taken if prescribed by a doctor. If you get dizziness, lightheadedness, fainting, or fast or racing heartbeats, consult a doctor. Do not stop taking any medications without visiting a doctor.
NorfloxacinCisapride
Critical
How does the drug interact with Nflox-B 400 mg Tablet:
Coadministration of Nflox-B 400 mg Tablet with Cisapride can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Nflox-B 400 mg Tablet with Cisapride together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
NorfloxacinSotalol
Critical
How does the drug interact with Nflox-B 400 mg Tablet:
Coadministration of Nflox-B 400 mg Tablet with Sotalol can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Nflox-B 400 mg Tablet with Sotalol together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
NorfloxacinMesoridazine
Critical
How does the drug interact with Nflox-B 400 mg Tablet:
Using Mesoridazine together with Nflox-B 400 mg Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Mesoridazine with Nflox-B 400 mg Tablet is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
NorfloxacinDisopyramide
Critical
How does the drug interact with Nflox-B 400 mg Tablet:
Coadministration of Nflox-B 400 mg Tablet with Disopyramide can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Nflox-B 400 mg Tablet with Disopyramide together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
NorfloxacinBepridil
Critical
How does the drug interact with Nflox-B 400 mg Tablet:
Using bepridil together with Nflox-B 400 mg Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Nflox-B 400 mg Tablet with Bepridil is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, or a fast or pounding heartbeat. Do not stop using any medications without talking to a doctor.
NorfloxacinHydrocortisone
Severe
How does the drug interact with Nflox-B 400 mg Tablet:
Coadministration of Nflox-B 400 mg Tablet and hydrocortisone can increase the risk or severity of tendinitis (inflammation of the tendons attached to the muscle and bones).

How to manage the interaction:
co-administration of Nflox-B 400 mg Tablet and hydrocortisone can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like pain, swelling, or inflammation of a tendon area such as the back of the ankle, shoulder, biceps, hand, or thumb, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
NorfloxacinInsulin glulisine
Severe
How does the drug interact with Nflox-B 400 mg Tablet:
Taking insulin glulisine with Nflox-B 400 mg Tablet affects blood glucose levels, which may cause hyperglycemia (high blood sugar) and hypoglycemia (low blood sugar) less frequently.

How to manage the interaction:
Although taking Nflox-B 400 mg Tablet and Insulin glulisine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience hypoglycemia or hyperglycemia. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, shaking, nausea, loss of hunger, weakness, sweating, palpitations, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without first talking to your doctor.
NorfloxacinOsimertinib
Severe
How does the drug interact with Nflox-B 400 mg Tablet:
Coadministration of Nflox-B 400 mg Tablet with Osimertinib can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Nflox-B 400 mg Tablet with Osimertinib together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
NorfloxacinTolbutamide
Severe
How does the drug interact with Nflox-B 400 mg Tablet:
Coadministration of Nflox-B 400 mg Tablet with Tolbutamide may sometimes affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.

How to manage the interaction:
Although there is a possible interaction, Nflox-B 400 mg Tablet can be taken with Tolbutamide if prescribed by the doctor. Consult the prescriber if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised.

Drug-Food Interactions

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BETADEX-10MG+NORFLOXACIN-400MGCaffeine containing foods/drinks, Fruit juices
Moderate

Drug-Food Interactions

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BETADEX-10MG+NORFLOXACIN-400MGCaffeine containing foods/drinks, Fruit juices
Moderate
Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu, Orange Juice

How to manage the interaction:
Consuming dairy products, cereal, or orange juice with Nflox-B 400 mg Tablet can interfere with its absorption and reduce its levels in the blood and urinary tract. Using caffeine together with Nflox-B 400 mg Tablet may increase the effects of caffeine. Nflox-B 400 mg Tablet dose should be taken at least one hour before or two hours after consuming dairy products, cereal, or orange juice. Avoid taking caffeine with Nflox-B 400 mg Tablet. Contact a doctor if you experience headaches, tremors, restlessness, nervousness, insomnia, and increased blood pressure or heart rate.

Diet & Lifestyle Advise

  • Drink plenty of water to stay hydrated.
  • Consume a well-balanced diet that includes fruits, vegetables, whole grains, and lean protein.
  • Engage in mild physical activity rather than intense exercise.
  • Limit dairy products (milk, cheese, yogurt) as they can interfere with absorption.
  • Avoid alcohol to reduce the risk of side effects.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS
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Alcohol

Unsafe

Avoid consumption of alcohol with Nflox-B 400 mg Tablet as it may increase drowsiness. Please consult a doctor before consuming alcohol with Nflox-B 400 mg Tablet .

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Pregnancy

Consult your doctor

Please consult a doctor if you are pregnant or planning for pregnancy. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

There is limited information on how Nflox-B 400 mg Tablet affects breastfeeding. Please consult your doctor before taking Nflox-B 400 mg Tablet if you are a breastfeeding mother.

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Driving

Unsafe

Nflox-B 400 mg Tablet may cause dizziness. Therefore, avoid driving if you feel dizzy after taking Nflox-B 400 mg Tablet .

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Liver

Consult your doctor

Consult your doctor before taking Nflox-B 400 mg Tablet if you have a liver impairment or any concerns regarding this.

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Kidney

Consult your doctor

Consult your doctor before taking Nflox-B 400 mg Tablet if you have a kidney problem or any concerns regarding this.

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Children

Consult your doctor

Nflox-B 400 mg Tablet should not be given to children as safety and effectiveness were not established. Please consult your doctor before giving Nflox-B 400 mg Tablet to your child.

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Heart

Please inform your doctor if you have any pre-existing heart problems before using Nflox-B 400 mg Tablet . Your doctor will prescribe Nflox-B 400 mg Tablet if the benefits outweigh the risk.

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Geriatrics

Consult your doctor

Please consult your doctor before giving Nflox-B 400 mg Tablet to elderly people. Your doctor will prescribe Nflox-B 400 mg Tablet if the benefits outweigh the risk.

FAQs

Nflox-B 400 mg Tablet is used to treat bacterial infections, including urinary tract infections, prostatitis (inflammation of the prostate), and gonorrhea (a sexually transmitted infection).

Nflox-B 400 mg Tablet is a combination of Betadex (Beta-Cyclodextrin) and Norfloxacin. The presence of beta-cyclodextrin improves the potency of norfloxacin. Norfloxacin works by blocking the production of the DNA gyrase enzyme, which leads to bacterial death and helps treat infections.

No, avoid dairy products, calcium-rich foods, and antacids, as they can reduce the effectiveness of norfloxacin.

If your condition does not improve after completing the full course of Nflox-B 400 mg Tablet inform your doctor. Also, notify them if your symptoms worsen during treatment. Your doctor may examine your condition, recommend further tests, or adjust your treatment if needed.

The duration of treatment varies according to the type of infection. Follow your doctor’s instructions and finish the full course to prevent the infection from coming back or becoming resistant.

Common side effects include abdominal cramps, nausea, headache, diarrhea, and dizziness. These side effects are generally mild and typically go away on their own over time. However, if they persist or become worse, consult your doctor for further guidance.

Country of origin

India

Manufacturer/Marketer address

E-11, Industrial Area, Panipat, Haryana-132103
Other Info - NFL0006

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Reference

  1. https://pmc.ncbi.nlm.nih.gov/articles/PMC4444636/#
  2. https://www.webmd.com/drugs/2/drug-11054/norfloxacin-oral/details
  3. https://www.mayoclinic.org/drugs-supplements/norfloxacin-oral-route/description/drg-20072239
  4. https://www.drugs.com/mtm/norfloxacin.html

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