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compositionComposition:CEFTRIAXONE-1000MG
prescription
Prescription Medicine
info
Nanocef 1 gm Injection

Nanocef 1 gm Injection is used to treat bacterial infections of the brain, lungs, middle ear, abdomen, urinary tract, kidneys, bones, joints, skin, soft tissues, blood, heart, chest, Lyme disease (caused by tick bites), and gonorrhoea (sexually transmitted disease). It contains Ceftriaxone, which kills the bacteria and helps in treating bacterial infection. In some cases, it may cause side effects such as diarrhoea, rashes, changes in results of blood and liver tests, and abnormalities (increase/decrease) in the number of white blood cells and platelets. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CEFTRIAXONE-1000MG

Manufacturer/Marketer :

Clariant Pharmaceuticals Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

NPPA :

Regulated

About Nanocef 1 gm Injection

Nanocef 1 gm Injection is a prescription injection antibiotic used to treat a wide variety of severe bacterial infections. It is commonly prescribed for serious conditions such as lung infections, meningitis, and infections of the skin, bones, or blood. This medication works by targeting and destroying the bacteria responsible for your illness, helping your body recover.

For this medication to work effectively, it must be injected consistently at the exact times prescribed by your healthcare provider. Because it is given as an injection, food intake does not affect how well it works, meaning it can be injected on an empty or full stomach. Incorporating plenty of rest and staying well-hydrated during your treatment course will significantly support your recovery.

While using Nanocef 1 gm Injection, you may experience mild side effects such as temporary pain at the injection site, mild nausea, or loose stools. However, you should contact your doctor immediately if you develop severe watery diarrhoea, a widespread skin rash, or yellowing of your skin and eyes.

Before starting treatment, it is vital to discuss your medical history with your doctor, especially if you have liver disease, kidney problems, or gallbladder issues. This medication must not be used in premature infants, newborns who require calcium-containing fluids through an intravenous line, or anyone with a known severe allergy to cephalosporin antibiotics.

Inform your healthcare provider about all medications you take, as this injection can interact with blood thinners and certain intravenous fluids. It is also wise to avoid alcohol during treatment, and special care should be taken if you are pregnant, breastfeeding, or an elderly patient. Talk to your doctor or pharmacist for personalised advice.

Uses of Nanocef 1 gm Injection

Nanocef 1 gm Injection is a broad-spectrum antibiotic used to treat a variety of serious bacterial infections and to prevent infections in certain surgical procedures.

  • Severe bacterial infections: Nanocef 1 gm Injection is used to treat serious infections affecting the bloodstream, bones, joints, abdomen, and other parts of the body by eliminating susceptible bacteria.
  • Bacterial meningitis: It helps treat infections of the membranes surrounding the brain and spinal cord by reaching effective concentrations within the central nervous system.
  • Community-acquired pneumonia: Nanocef 1 gm Injection is used to treat bacterial lung infections, helping clear the infection and improve breathing.
  • Urinary tract infections (UTIs): It is effective against many bacteria responsible for complicated infections of the bladder, urinary tract, and kidneys.
  • Surgical infection prevention: The medication may be given before certain surgical procedures to reduce the risk of postoperative bacterial infections.
  • Gonorrhoea: Nanocef 1 gm Injection is commonly used as an effective treatment for uncomplicated gonorrhoea caused by susceptible strains of bacteria.

Key Benefits

Nanocef 1 gm Injection provides effective treatment for serious bacterial infections and helps promote faster recovery when used as prescribed.

  • Provides rapid antibacterial action: Because it is administered by injection, Nanocef 1 gm Injection enters the bloodstream directly and begins fighting susceptible bacteria quickly.
  • Helps treat severe infections effectively: It is often used when infections are serious, widespread, or unlikely to respond adequately to oral antibiotics.
  • Offers convenient once-daily dosing for many infections: Its long duration of action often allows treatment with a single daily dose, improving convenience and treatment adherence.
  • Provides broad-spectrum bacterial coverage: Nanocef 1 gm Injection is active against a wide range of bacteria, making it useful for treating various types of infections.
  • Supports recovery and symptom relief: By eliminating the bacteria causing the infection, it helps reduce symptoms such as fever, pain, inflammation, and discomfort.
  • Helps prevent surgical site infections: When used before surgery, it can reduce the likelihood of bacterial infections developing after the procedure.
  • Remains effective against many resistant bacteria: Nanocef 1 gm Injection is stable against certain bacterial resistance mechanisms, making it a reliable treatment option for many difficult-to-treat infections.
Side effects of Nanocef 1 gm Injection
Managing Medication-Triggered Thrombophlebitis (Inflammation of a vein): A Step-by-Step Guide:
  • If you have symptoms such as pain, swelling, redness, or warmth in your veins after taking medication, contact your doctor right once. Share information about your symptoms, medication regimen, and medical history.
  • Your doctor will then assess your medication regimen to determine if it's contributing to the thrombophlebitis. This assessment will help identify the best course of action to manage your condition and prevent further complications.
  • Your doctor may suggest certain diet and lifestyle changes to help manage your condition. This may include increasing your intake of foods rich in omega-3 fatty acids, staying hydrated, exercising regularly, and maintaining a healthy weight. Your doctor may also advise medications to reduce inflammation, prevent blood clots, or manage pain if necessary.
  • If your condition does not improve or persists, consult your doctor and report your condition. Your doctor will assess your progress, adjust your treatment plan if necessary, and provide appropriate advice to ensure the best possible outcome.
  • If you notice swelling, pain, redness, or pus at the injection site, contact your doctor for advice and appropriate care.
  • Use ice packs on the injection site for at least 20 minutes multiple times a day.
  • Rest the affected area and elevate it to reduce inflammation if possible.
  • Avoid intense physical activity that could worsen the injection site.
  • If you need regular injections, try using different spots to avoid severe inflammation in one place.
  • Consider using medications like ibuprofen or paracetamol to relieve pain, and hydrocortisone cream or anti-itch lotion to ease swelling and discomfort.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
  • Eat foods rich in vitamins C and E, and healthy fats.
  • Consider soft foods like smoothies, soups, and scrambled eggs.
  • Take supplements like vitamins C and E, zinc, and omega-3 fatty acids under medical supervision.
  • Include anti-inflammatory foods like omega-3 rich foods, berries, leafy greens, and spices.
  • Avoid allergens and consider an elimination diet.
  • Practice gentle skin care with non-irritating cleansers and moisturizers.
  • Keep skin well-moisturized with fragrance-free products.
  • Monitor for complications like infection and temperature regulation.
  • Let your doctor know if there are unsual symptoms after taking the medication, such as red patches on your skin.
  • Your doctor may change your medication, lower the dose, or stop the treatment to help manage the symptoms.
  • Avoid heavy physical activity and get plenty of rest to prevent further worsening of the symptoms.
  • Apply cold packs to the affected areas for relief.
  • Keep yourself hydrated or take supplements to get enough vitamins.
  • Over-the-counter pain relievers can help with discomfort.

Directions for Use

To ensure the best treatment outcomes, Nanocef 1 gm Injection should be administered exactly as prescribed by your healthcare provider.

  • Nanocef 1 gm Injection is given as an injection, either into a muscle (intramuscularly) or into a vein (intravenously), usually by a trained healthcare professional.
  • The medication may be administered in a hospital, clinic, or home-care setting, depending on your treatment plan.
  • If you have been instructed to administer Nanocef 1 gm Injection at home, ensure you receive proper training on preparation, handling, and injection techniques before use.
  • Check the prepared solution before administration. It should generally appear clear and free from visible particles. Do not use the medication if it appears cloudy, discoloured, or contains particles.
  • Administer the medication at the times recommended by your doctor to maintain effective levels in the body.
  • Complete the full course of treatment exactly as prescribed, even if you start feeling better before the treatment is finished.
  • Do not skip doses or stop treatment early unless instructed by your healthcare provider, as this may reduce treatment effectiveness and increase the risk of antibiotic resistance.

How Nanocef 1 gm Injection Works

Nanocef 1 gm Injection belongs to a group of medicines known as cephalosporin antibiotics. It works by interfering with the formation of the bacterial cell wall. Bacteria require a strong, fully formed cell wall to protect themselves from their environment and to survive. By blocking the chemical processes needed to build these walls, the medication causes the bacterial cells to develop leaks and rupture. This directly kills the bacteria causing the illness, allowing your body's natural immune system to easily clear the remaining infection.
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Alcohol

Caution

Avoid consuming alcohol while taking Nanocef 1 gm Injection to prevent unpleasant side-effects.

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Pregnancy

Caution

Please consult your doctor if you are pregnant; your doctor will prescribe Nanocef 1 gm Injection only if the benefits outweigh the risks.

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Breast Feeding

Caution

Please consult your doctor if you are breastfeeding; your doctor will prescribe Nanocef 1 gm Injection only if the benefits outweigh the risks.

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Driving

Caution

Nanocef 1 gm Injection may cause dizziness, do not drive or operate heavy machinery if you feel dizzy.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or if you have liver impairment/liver disease.

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Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease.

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Children

Safe if prescribed

Nanocef 1 gm Injection is safe for children if prescribed by a doctor. Nanocef 1 gm Injection is not recommended for a premature baby, or a newborn baby who has jaundice (yellowing of the skin or eyes).

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Heart

Consult your doctor

Please consult your doctor before receiving Nanocef 1 gm Injection if you have pre-existing heart problems. Your doctor will administer Nanocef 1 gm Injection if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Please consult a doctor before administering Nanocef 1 gm Injection to geriatric patients. Your doctor will prescribe Nanocef 1 gm Injection if the benefits outweigh the risks.

What if I have taken an overdose of Nanocef 1 gm Injection

The overdose of Nanocef 1 gm Injection is unlikely as it is administered by a doctor. However, if you suspect any adverse reactions or unusual symptoms while on treatment with Nanocef 1 gm Injection, please inform your doctor immediately.

Diet & Lifestyle Advise

  • Stay Well-Hydrated: Drink plenty of water throughout the day to help your kidneys process and safely eliminate the medication from your body.
  • Support Gut Health: Eat probiotic-rich foods (such as yoghurt or kefir) or take a probiotic supplement a few hours after your injection to help maintain healthy gut bacteria and minimise stomach upset.
  • Get Adequate Rest: Prioritise rest and avoid strenuous physical activities to give your immune system the energy it needs to fight off the infection.
  • Avoid Alcohol: Avoid drinking alcohol during your treatment, as it can strain your digestive system and liver while your body is recovering.

Have a query?

How Soon It Starts Working

The time required for Nanocef 1 gm Injection to start to work: Nanocef 1 gm Injection ideally shows its action within 1 to 2 hours after administration. The time for which the effects of Nanocef 1 gm Injection last: The effect of Nanocef 1 gm Injection lasts for 48 hours.

What if you forget to take Nanocef 1 gm Injection

As this medication will be administered in a hospital by your healthcare professional, the chances of missing a dose are less. However, if you have any concerns, contact your doctor.

Storage

• Store unmixed (dry powder) Nanocef 1 gm Injection vials at room temperature, typically between 20°C and 25°C (68°F and 77°F). • Keep the vials in their original packaging to protect them from light and moisture.

Drug Warnings

  • Inspect the Solution Before Use: Always check the liquid solution before injecting. Do not use it if it appears cloudy, contains floating particles, or has changed to a dark colour.
  • Avoid Mixing With Calcium-Containing Fluids: Never mix Nanocef 1 gm Injection with any fluids containing calcium in the same intravenous line, as this can cause dangerous solid particles to form.
  • Rotate Injection Sites: If you are receiving intramuscular injections, rotate your injection sites regularly to help prevent muscle soreness and tissue hardening.
  • Monitor for Injection Site Reactions: Watch the injection site closely and contact your doctor if you notice worsening redness, warmth, throbbing pain, swelling, or pus.
  • Inform Healthcare Providers: Tell all of your healthcare providers, including your dentist, that you are being treated with Nanocef 1 gm Injection before undergoing any medical tests, procedures, or surgeries.

Drug-Drug Interactions

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Drug-Drug Interactions

Nanocef 1 gm Injection may interact with certain medications, requiring additional monitoring or precautions during treatment.

  • Calcium-containing intravenous solutions: Nanocef 1 gm Injection should not be mixed or administered simultaneously with calcium-containing intravenous products through the same infusion line, particularly in newborns, as this can result in the formation of precipitates that may cause serious complications.
  • Blood thinners (such as warfarin): Using Nanocef 1 gm Injection together with anticoagulants may increase the risk of bleeding and may require monitoring of blood clotting parameters.
  • Aminoglycosides and certain other antibiotics: Concurrent use may increase the risk of kidney-related side effects, particularly in patients with existing kidney impairment.


Drug-Disease Interactions

Certain medical conditions may require closer monitoring while receiving Nanocef 1 gm Injection.

  • Gallbladder disease: Nanocef 1 gm Injection may cause biliary sludge or calcium-containing deposits in the gallbladder, which can mimic gallstones or worsen existing gallbladder conditions.
  • History of colitis or gastrointestinal disease: Antibiotic treatment can increase the risk of severe diarrhoea, including antibiotic-associated colitis, particularly in susceptible individuals.
  • Severe kidney and liver impairment: Patients with significant impairment of both kidney and liver function may require dose adjustments and careful monitoring during treatment.
CeftazidimeBCG vaccine
Critical
CeftazidimeCholera, live attenuated
Severe

Drug-Drug Interactions

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CeftazidimeBCG vaccine
Critical
How does the drug interact with Nanocef 1 gm Injection:
When BCG vaccine is used with Nanocef 1 gm Injection, its effectiveness may be reduced.

How to manage the interaction:
Taking Nanocef 1 gm Injection with BCG vaccine is not recommended, but can be taken together if prescribed by a doctor. In case you experience any unusual side effects, consult a doctor. Do not discontinue any medications without consulting a doctor.
CeftazidimeCholera, live attenuated
Severe
How does the drug interact with Nanocef 1 gm Injection:
Taking the cholera vaccine after or along with Nanocef 1 gm Injection may reduce the activity of the vaccine.

How to manage the interaction:
Although taking Nanocef 1 gm Injection with Cholera, live attenuated can possibly result in an interaction, but it can be taken if your doctor has advised it. You should wait at least 14 days after finishing your antibiotic treatment before receiving the cholera vaccine in order to ensure an appropriate immune response. Do not stop using any medications without a doctor's advice.
CeftazidimeCholera vaccines
Severe
How does the drug interact with Nanocef 1 gm Injection:
Taking the cholera vaccine after or along with Nanocef 1 gm Injection may reduce the activity of the vaccine.

How to manage the interaction:
Although there is a possible interaction between Nanocef 1 gm Injection and Cholera vaccines, you can take these medicines together if prescribed by your doctor. You should wait at least 14 days after finishing your antibiotic treatment before receiving the cholera vaccine in order to ensure an appropriate immune response. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]

FAQs

Nanocef 1 gm Injection is used to treat bacterial infections of the brain, lungs, middle ear, abdomen, urinary tract, kidneys, bones, joints, skin, soft tissues, blood, heart, chest, lime disease (caused by tick bites), and gonorrhoea (sexually transmitted disease).
Nanocef 1 gm Injection works by preventing the formation of bacterial cell covering, which is necessary for their survival. Thereby, kills the bacteria and helps in treating and preventing the spread of infections.
Nanocef 1 gm Injection may cause dizziness, so drive only if you are alert and omit driving and operating machinery if you experience dizziness.
Nanocef 1 gm Injection may affect the results of urine tests for sugar and blood test known as coomb’s test (antiglobulin test). Inform the person performing the tests that you are taking Nanocef 1 gm Injection.
Do not take antacids along with Nanocef 1 gm Injection; maintain a gap of 2-3 hours between both. However, consult your doctor before taking other medicines while on treatment with Nanocef 1 gm Injection.
Yes, Nanocef 1 gm Injection is generally considered safe when taken in the recommended dose and duration as directed by your doctor. However, sometimes it may cause side effects or allergic reactions in some individuals. Please let your doctor know if any of the side effects bother you.
Nanocef 1 gm Injection usually starts working within a few hours after administration. However, Nanocef 1 gm Injection may take a few days to show its full effect, depending on the infection being treated. If your symptoms do not improve or get worse, please consult your doctor.
Nanocef 1 gm Injection should not be used by individuals who are allergic to its components or other cephalosporin antibiotics. It is also not recommended for use in newborns, especially those with jaundice (yellowing of the skin or eyes).
If you do not feel better after using Nanocef 1 gm Injection, it could mean that the infection isn't responding to the antibiotic, or you might have a different type of infection that needs a different treatment. Please consult your doctor for further evaluation and to discuss possible changes to your treatment plan.
Yes, Nanocef 1 gm Injection is effective against a wide range of bacterial infections, including respiratory, urinary tract, skin, and bloodstream infections.
Nanocef 1 gm Injection will be administered either intravenously (IV) or intramuscularly (IM), depending on the condition being treated, by your healthcare provider. Please do not self-administer.
No, you should complete the full course of treatment with Nanocef 1 gm Injection as prescribed by your doctor, even if you feel better. Please consult your doctor before stopping the medication early, as your infection may not be completely treated and the bacteria may become resistant to the antibiotics.
If you are allergic to Cefuroxime, there is a possible risk of an allergic reaction to Nanocef 1 gm Injection, since both are in the same group of antibiotics (cephalosporins). Please consult your healthcare provider before taking Nanocef 1 gm Injection or any other cephalosporin antibiotics to ensure safety.
Before starting Nanocef 1 gm Injection, you should inform your doctor if you have recently received calcium-containing products, have had diarrhoea after taking antibiotics, or have a history of colitis (inflammation of the large intestine), malnutrition (inability to consume or digest essential nutrients), problems with vitamin K levels, or kidney or liver disease.
No, Nanocef 1 gm Injection should only be administered by a healthcare professional, as it requires proper injection technique and monitoring for potential side effects. Please do not administer Nanocef 1 gm Injection at home.
No, Nanocef 1 gm Injection belongs to the cephalosporin class of antibiotics. However, because they are chemically related to penicillins, you must tell your doctor if you have ever had a severe allergic reaction to penicillin. Talk to your doctor or pharmacist.
Intramuscular injections can cause temporary stinging or aching because of the volume of the medicine entering the muscle. Healthcare providers often mix the powder with a local numbing medicine (like lidocaine) to make the injection much more comfortable. Talk to your doctor or pharmacist.
Yes, for certain infections like uncomplicated gonorrhoea, a single intramuscular injection of Nanocef 1 gm Injection is often highly effective and sufficient to cure the infection. For other severe infections, a multi-day course is required. Talk to your doctor or pharmacist.
This medicine is long-acting, which is why it is usually given only once a day. It can take several days after your last dose for the active medication to be completely cleared from your body. Talk to your doctor or pharmacist.
No, Nanocef 1 gm Injection is an antibiotic that only kills bacteria. It will not work against viral infections like the common cold, flu, or COVID-19. Talk to your doctor or pharmacist.
Contact your healthcare provider immediately to reschedule your dose. Keeping steady levels of the medication in your body is critical to successfully curing the bacterial infection. Talk to your doctor or pharmacist.
Yes, diarrhoea is a possible side effect of Nanocef 1 gm Injection. Drink plenty of fluids and eat simple, non-spicy foods. If the diarrhoea becomes severe, watery, or bloody, do not take anti-diarrhoeal medicines without medical advice and contact your doctor immediately, as this may indicate a serious bowel infection.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. U.S. Food and Drug Administration (FDA). 0550585S063Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026] Check here
  2. Drugs.com Clinical Review Team. Ceftriaxone Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  3. National Center for Biotechnology Information (NCBI). Ceftriaxone Scientific Research Publication. Bethesda, MD: NLM; 2025. [Accessed on 02 Jun. 2026] Check here
  4. Ceftriaxone Ceftriaxone. 2013. [Accessed on 07 Feb. 2019] Check here
  5. Ceftriaxone Ceftriaxone. [Accessed on 19 Mar. 2025] Check here
  6. Rocephin 1g Powder for Solution for Injection or Infusion [Internet]. Accessdata.fda.gov. 2021 [Accessed on 18 November 2025] Check here
  7. CEFBACT Injection [Internet]. CiplaMed. 2021 [Accessed on 18 November 2025]Check here

Country of origin

India

Manufacturer/Marketer address

Tinsukia, Assam
Other Info - NAN0172

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