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Nazomac-AF Nasal Spray 12 ml, Pack of 1 Nasal Spray
Nazomac-AF Nasal Spray 12 ml, Pack of 1 Nasal Spray
Nazomac-AF Nasal Spray 12 ml, Pack of 1 Nasal Spray
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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Nazomac-AF Nasal Spray 12 ml is used to treat allergic symptoms like sneezing, runny nose, congestion, stuffy nose or watery eyes. It contains Fluticasone and Azelastine, which work by acting inside the nasal lining cells and stopping the release of certain chemicals in the body that cause inflammatory reactions, thereby relieving sneezing, runny or blocked nose, and sinus discomfort. Also, it blocks histamine, a substance responsible for causing allergic reactions. Some people may experience side effects such as headaches, taste changes or nose bleeds. Before using this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

AZELASTINE-140MCG + FLUTICASONE-50MCG

Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

NASAL

Return Policy :

Not Returnable

Expires on or after :

About Nazomac-AF Nasal Spray 12 ml

Nazomac-AF Nasal Spray 12 ml is used to treat allergic symptoms like sneezing, runny nose, congestion, stuffy nose or watery eyes. An allergy is a condition that occurs when the immune system reacts to a foreign substance. These foreign substances are known as 'allergens.' Allergic condition varies from person to person. Some might be allergic to certain foods and seasonal allergies like hay fever, pollen or pet dander. One of the main symptoms of allergy is cough, which acts as a reflex action in the throat when there is any mucus or foreign irritant entering the respiratory system.

Nazomac-AF Nasal Spray 12 ml is a combination of two drugs: Fluticasone (corticosteroid) and Azelastine (antihistamine/antiallergic). Fluticasone belongs to the class of corticosteroids that works by acting inside the nasal lining cells and stopping the release of certain chemicals in the body that cause inflammatory reactions, thereby relieving sneezing, runny or blocked nose, and sinus discomfort. On the other hand, Azelastine belongs to the class of antihistamines (antiallergic drugs) that works by blocking histamine, a substance responsible for causing allergic reactions. It helps relieve allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion, or stiffness. Together, both of them effectively treat allergic symptoms.

Take Nazomac-AF Nasal Spray 12 ml as advised by your doctor by spraying towards the sides of nostrils. Your doctor will recommend how often you take Nazomac-AF Nasal Spray 12 ml based on your medical condition. Some people may experience headaches, taste changes or nose bleeds. Most of these side effects of Nazomac-AF Nasal Spray 12 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Inform your doctor if you are allergic to Nazomac-AF Nasal Spray 12 ml or any other medicines, are pregnant or breastfeeding before using Nazomac-AF Nasal Spray 12 ml. Nazomac-AF Nasal Spray 12 ml is not recommended for children below six years of age. If you experience vision changes, tiredness, nausea, vomiting, light-headedness, chills, fever, body pains, sores, redness or white patches in the mouth or throat, runny nose, severe nosebleeds, or increased drowsiness, stop taking Nazomac-AF Nasal Spray 12 ml and consult a doctor immediately. Avoid contact with people who have infections or are sick, as the Nazomac-AF Nasal Spray 12 ml may weaken the immune system, causing infections easily. If you have chickenpox, measles, tuberculosis, surgery or injury on the nose, glaucoma, cataracts, herpes infection of eyes, ulcers, or sores inside the nose, inform your doctor before taking Nazomac-AF Nasal Spray 12 ml.

Uses of Nazomac-AF Nasal Spray 12 ml

Treatment of Allergic symptoms like sneezing, runny nose, congestion, stuffy nose or watery eyes.

Directions for Use

• Nazomac-AF Nasal Spray 12 ml is for nasal use only.• It is recommended to spray Nazomac-AF Nasal Spray 12 ml twice daily into each nostril, or as prescribed by your doctor.• Check the label for directions before using Nazomac-AF Nasal Spray 12 ml.• Shake the nasal spray bottle gently before each use.• Blow your nose and remove the protective cap. Before the first use, press the pump a few times until an even spray is released. • Insert the tip of the bottle into a nostril while closing the other nostril and spray the medicine into your nose. Keep your head straight and breathe gently. Repeat the same process for the other nostril.• If Nazomac-AF Nasal Spray 12 ml accidentally gets sprayed into your mouth or eyes, rinse with water thoroughly.

Medicinal Benefits

Nazomac-AF Nasal Spray 12 ml is primarily used to treat allergic symptoms like sneezing, runny nose, congestion, stuffy nose or watery eyes. It combines two drugs: Fluticasone (corticosteroid) and Azelastine (antihistamine/antiallergic). Fluticasone belongs to the class of corticosteroids that works by acting inside the nasal lining cells and stopping the release of certain chemicals in the body that cause inflammatory reactions, thereby relieving sneezing, runny or blocked nose and sinus discomfort. On the other hand, Azelastine belongs to the antihistamines class (antiallergic drugs), which works by blocking histamine, a substance responsible for causing allergic reactions. It helps relieve allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion or stiffness. Together, both of them effectively treat allergic symptoms.

How Nazomac-AF Nasal Spray 12 ml Works

Nazomac-AF Nasal Spray 12 ml is a combination of two drugs: Fluticasone (corticosteroid) and Azelastine (antihistamine/antiallergic). Fluticasone belongs to the class of corticosteroids that works by acting inside the nasal lining cells and stopping the release of certain chemicals in the body that cause inflammatory reactions, thereby relieving sneezing, runny or blocked nose, and sinus discomfort. On the other hand, Azelastine belongs to the class of antihistamines (antiallergic drugs) that works by blocking histamine, a substance responsible for causing allergic reactions. It helps relieve allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion, or stiffness. Together, both of them effectively treat allergic symptoms.

Storage

Keep Nazomac-AF Nasal Spray 12 ml out of the sight and reach of children.

What if I have taken an overdose of Nazomac-AF Nasal Spray 12 ml

Do not use Nazomac-AF Nasal Spray 12 ml in more doses or more often than prescribed. If you have any unusual signs or symptoms, please consult a doctor immediately.

Drug Warnings

Please inform your doctor if you are allergic to Nazomac-AF Nasal Spray 12 ml or any other medicines. Do not use the Nazomac-AF Nasal Spray 12 ml if you are pregnant or breastfeeding without consulting the doctor. Nazomac-AF Nasal Spray 12 ml is not recommended for children below six years of age. If you experience vision changes, tiredness, nausea, vomiting, light-headedness, chills, fever, body pains, sores, redness or white patches in the mouth or throat, runny nose, severe nosebleeds, or increased drowsiness, stop taking Nazomac-AF Nasal Spray 12 ml and consult a doctor immediately. Avoid contact with people who have infections or are sick as Nazomac-AF Nasal Spray 12 ml may weaken the immune system, causing infections easily. If you have chickenpox, measles, tuberculosis, surgery or injury on the nose, glaucoma, cataracts, herpes infection of eyes, ulcers, or sores inside the nose, inform your doctor before taking Nazomac-AF Nasal Spray 12 ml.

Drug-Drug Interactions

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FluticasoneMifepristone
Critical
FluticasoneClarithromycin
Severe

Drug-Drug Interactions

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FluticasoneMifepristone
Critical
How does the drug interact with Nazomac-AF Nasal Spray 12 ml:
Co-administration of Nazomac-AF Nasal Spray 12 ml with Mifepristone may make Nazomac-AF Nasal Spray 12 ml less effective as a therapy.

How to manage the interaction:
Taking Nazomac-AF Nasal Spray 12 ml with Mifepristone is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
FluticasoneClarithromycin
Severe
How does the drug interact with Nazomac-AF Nasal Spray 12 ml:
Co-administration of Nazomac-AF Nasal Spray 12 ml with Clarithromycin may significantly increase the absorption of Nazomac-AF Nasal Spray 12 ml into the blood stream.

How to manage the interaction:
Co-administration of Clarithromycin and Nazomac-AF Nasal Spray 12 ml can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like swelling, weight gain, high blood pressure, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
FluticasoneTelaprevir
Severe
How does the drug interact with Nazomac-AF Nasal Spray 12 ml:
Co-administration of Telaprevir may significantly increase the absorption of Nazomac-AF Nasal Spray 12 ml into the bloodstream.

How to manage the interaction:
Taking Nazomac-AF Nasal Spray 12 ml with Telaprevir together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms - swelling, weight gain, high blood pressure, high blood sugar, weak muscles, feeling down, acne, thinning skin, easy bruising, irregular periods, too much facial or body hair, unusual fat distribution, infection, or a bad asthma attack - make sure to call a doctor right away. Do not stop using any medications without a doctor's advice.
FluticasoneDinutuximab
Severe
How does the drug interact with Nazomac-AF Nasal Spray 12 ml:
Co-administration of Dinutuximab and Nazomac-AF Nasal Spray 12 ml may increase the risk of serious and potentially infections.

How to manage the interaction:
Co-administration of Dinutuximab and Nazomac-AF Nasal Spray 12 ml can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
FluticasoneDesmopressin
Severe
How does the drug interact with Nazomac-AF Nasal Spray 12 ml:
Co-administration of Desmopressin with Nazomac-AF Nasal Spray 12 ml may increase the risk of hyponatremia (low levels of salt in the blood).

How to manage the interaction:
If you have to use Desmopressin and Nazomac-AF Nasal Spray 12 ml together, a doctor may adjust the dose or monitor you more frequently to safely use both medications. However, if you experience loss of appetite, headache, nausea, vomiting, lethargy (very tired), irritability, difficulty concentrating, weakness, unsteadiness, memory impairment, confusion, muscle spasm, decreased urination, and/or sudden weight gain, contact a doctor immediately as these may be symptoms of water intoxication (water poisoning) and hyponatremia (low levels of salt in the blood). Do not discontinue the medication without consulting a doctor.
FluticasoneIndinavir
Severe
How does the drug interact with Nazomac-AF Nasal Spray 12 ml:
Indinavir may increase the absorption of Nazomac-AF Nasal Spray 12 ml into the bloodstream and increase the risk of side effects.

How to manage the interaction:
If you are supposed to take Nazomac-AF Nasal Spray 12 ml and Indinavir together, your doctor may adjust the dose or monitor you more frequently to use both medications safely. However, if you experience side effects such as weight gain, high blood pressure, swelling, muscle weakness, acne, depression, thinning skin, easy bruising, stretch marks, bone density loss, cataracts, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, contact your doctor.
FluticasoneItraconazole
Severe
How does the drug interact with Nazomac-AF Nasal Spray 12 ml:
Coadministration of Itraconazole and Nazomac-AF Nasal Spray 12 ml may significantly increase the absorption of Nazomac-AF Nasal Spray 12 ml into the bloodstream.

How to manage the interaction:
Nazomac-AF Nasal Spray 12 ml and itraconazole may interact, but if a doctor prescribes them, you can still use them. Swelling, high blood pressure, high blood sugar, muscle weakness, depression, acne, stretch marks, easy bruising, bone density loss, cataracts, irregular menstruation, and excessive face or body hair growth are all signs that you need to consult a doctor. Never discontinue taking a medication without consulting a doctor.
FluticasoneTelithromycin
Severe
How does the drug interact with Nazomac-AF Nasal Spray 12 ml:
When Nazomac-AF Nasal Spray 12 ml is taken with Telithromycin, it can lower the rate at which Telithromycin is broken down in the body.

How to manage the interaction:
Although there is a possible interaction between Nazomac-AF Nasal Spray 12 ml and Telithromycin, you can take these medicines together if prescribed by a doctor. If you notice any of these symptoms - swelling, weight gain, high blood pressure, high blood sugar, weak muscles, feeling down, acne, thinning skin, easy bruising, irregular periods, too much facial or body hair, strange fat distribution, bruising, infection, or a bad asthma attack - make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
FluticasoneAmprenavir
Severe
How does the drug interact with Nazomac-AF Nasal Spray 12 ml:
Co-administration of Amprenavir and Nazomac-AF Nasal Spray 12 ml may significantly increase the absorption of Nazomac-AF Nasal Spray 12 ml into the blood stream.

How to manage the interaction:
Co-administration of Amprenavir and Nazomac-AF Nasal Spray 12 ml can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like swelling, weight gain, high blood pressure, muscle weakness, depression, acne, thinning skin, stretch marks, easy bruising, bone density loss, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
FluticasoneSaquinavir
Severe
How does the drug interact with Nazomac-AF Nasal Spray 12 ml:
Co-administration of Saquinavir may increase the absorption of Nazomac-AF Nasal Spray 12 ml into the bloodstream and increase the risk of side effects.

How to manage the interaction:
If you are supposed to take Nazomac-AF Nasal Spray 12 ml and Saquinavir together, a doctor may adjust the dose or monitor you more frequently to use both medications safely. However, if you experience side effects such as weight gain, high blood pressure, swelling, high blood sugar, muscle weakness, acne, depression, thinning skin, easy bruising, stretch marks, bone density loss, cataracts, menstrual irregularities, excessive growth of facial or body hair, and abnormal distribution of body fat, especially in the face, neck, back, and waist, contact a doctor. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Add ginger to foods or tea as it contains some anti-inflammatory compounds that can relax membranes in the airways and reduce cough, irritation and swelling in nasal passages.
  • Staying hydrated is vital for those with a cough or cold. Drink liquids at room temperature to relieve a runny nose, cough, and sneezing.
  • Stress affects the immune system and raises the risk of illness. To relieve stress, meditate, deepen breathing, and engage in regular exercise. You can also try progressive muscle relaxation techniques.
  • It is advised to avoid contact with known allergens (allergy-causing agents) such as pollen, dust, etc. Certain food items are known to cause allergies to you.
  • Maintain personal hygiene and keep your surroundings clean.

Habit Forming

No

Therapeutic Class

ANTIALLERGIC

Nazomac-AF Nasal Spray 12 ml Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

It is unknown whether it is safe to consume alcohol with Nazomac-AF Nasal Spray 12 ml. However, as a precautionary measure, it is advisable not to take or limit alcohol.

bannner image

Pregnancy

Caution

The safety of Nazomac-AF Nasal Spray 12 ml in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

bannner image

Breast Feeding

Caution

It is unknown whether Nazomac-AF Nasal Spray 12 ml is excreted in human milk. It is given to breastfeeding mothers only if the doctor thinks the benefits are greater than the risks.

bannner image

Driving

Caution

Nazomac-AF Nasal Spray 12 ml may cause drowsiness in some people. Therefore, drive only if you are alert after taking Nazomac-AF Nasal Spray 12 ml.

bannner image

Liver

Safe if prescribed

Inform your doctor before prescribing the Nazomac-AF Nasal Spray 12 ml if you have a history of liver impairment/disorder. Your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Kidney

Safe if prescribed

Inform your doctor before receiving the Nazomac-AF Nasal Spray 12 ml if you have had a kidney impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Children

Caution

Nazomac-AF Nasal Spray 12 ml is not recommended for children below six years as the safety and effectiveness were not established.

Have a query?

FAQs

Nazomac-AF Nasal Spray 12 ml is used to treat allergic symptoms like sneezing, runny nose, congestion, stuffy nose or watery eyes.

Nazomac-AF Nasal Spray 12 ml is a combination of two drugs: Fluticasone (corticosteroid) and Azelastine (antihistamine/antiallergic). Fluticasone belongs to the class of corticosteroids that works by acting inside the nasal lining cells and stopping the release of certain chemicals in the body that cause inflammatory reactions, thereby relieving sneezing, runny or blocked nose and sinus discomfort. On the other hand, Azelastine belongs to the class of antihistamines (antiallergic drugs) that works by blocking histamine, a substance responsible for causing allergic reactions. It helps relieve allergy symptoms such as sneezing, runny nose, watery eyes, itching, swelling, congestion, or stiffness. Together, both of them effectively treat allergic symptoms.

It is recommended that you avoid taking grapefruit juice with Nazomac-AF Nasal Spray 12 ml as it may lead to adrenal insufficiency and Cushing’s syndrome (increased cortisol hormone in the body).

Your rhinitis symptoms may improve over several days of regular use. Call your healthcare provider if your symptoms do not improve or worsen.

You are not recommended to take more than the prescribed dose of Nazomac-AF Nasal Spray 12 ml or for a prolonged time as it may cause adverse effects such as changes in body fat (especially in the back, waist, neck, and face), easy bruising, skin thinning, increased facial hair or acne, loss of interest in sex, impotence or menstrual problems. However, if you experience any of these symptoms while taking Nazomac-AF Nasal Spray 12 ml, please consult a doctor immediately.

No, you are recommended not to use Nazomac-AF Nasal Spray 12 ml if you have a recent nose operation or have any nose infections as it may lead to nose bleeding and excessive pain in the nose, leading to further worsening of your condition. Consult your doctor and do as advised for the best results.

No, Nazomac-AF Nasal Spray 12 ml is not used to treat asthma attacks. It is used to prevent allergic symptoms that can cause asthma. Therefore, it is recommended to always carry a rescue inhaler to treat asthma attacks.

Nazomac-AF Nasal Spray 12 ml contains Fluticasone which belongs to the class of corticosteroids, and it may result in the development of glaucoma and/or cataracts. Therefore, close monitoring is warranted in patients with a change in vision or a history of increased intraocular pressure, glaucoma, and/or cataracts.

Use Nazomac-AF Nasal Spray 12 ml as advised by your doctor. Place the tip of the bottle into one nostril while closing the other nostril. Spray towards the side of your nostril, keeping your head upright and breathing in softly.

Store in a cool and dry place at room temperatures. Protect from light. Keep it out of reach of children. Do not refrigerate. Follow the local guidelines for disposal of Nazomac-AF Nasal Spray 12 ml.

Nazomac-AF Nasal Spray 12 ml causes side effects as headache, nose bleeds, and taste change. These side effects do not require any medical treatment. They will reduce by time.

Country of origin

India

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.
Other Info - NAZ0012

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:39 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/202236s008lbl.pdf
  2. https://www.medicines.org.uk/emc/files/pil.9450.pdf
  3. https://www.drugs.com/cdi/azelastine-and-fluticasone.html

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