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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Neopam 1Gm Injection is used to treat poisoning caused by organic phosphorus pesticides or chemicals. It is also used to treat an overdose of drugs that treat myasthenia gravis. It contains Pralidoxime, a cholinesterase reactivator. It works by reactivating the enzyme cholinesterase (mainly outside the central nervous system), which has been inactivated by phosphorylation due to an organophosphate pesticide or related compound.

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Whats That

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Composition :

PRALIDOXIME-500MG

Manufacturer/Marketer :

Troikaa Pharmaceuticals Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Neopam 1Gm Injection

Neopam 1Gm Injection belongs to the oxime class of drugs. Pralidoxime is used alone or together with atropine to treat poisoning caused by organic phosphorus pesticides or chemicals. It is also used to treat an overdose of drugs that treat myasthenia gravis.

Neopam 1Gm Injection contains Pralidoxime, a cholinesterase reactivator. It works by reactivating the enzyme cholinesterase (mainly outside the central nervous system), which has been inactivated by phosphorylation due to an organophosphate pesticide or related compound.

A qualified healthcare professional will administer Neopam 1Gm Injection. You may experience mild to moderate pain at the site of injection, blurred vision, diplopia (double vision), impaired accommodation, dizziness, headache, drowsiness, nausea, tachycardia (fast heartbeat), increased systolic and diastolic blood pressure, hyperventilation (rapid or deep breathing), and muscular weakness. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, inform your doctor.

Before taking Neopam 1Gm Injection, let your doctor know about all your medical conditions, sensitivities, and ongoing medications. Also, inform your doctor if you are pregnant, planning pregnancy, or breastfeeding. Neopam 1Gm Injection may cause blurred vision and diplopia (double vision); it impacts your ability to drive or operate machinery.

Uses of Neopam 1Gm Injection

Treatment of Organophosphate poisoning

Directions for Use

A qualified healthcare professional will administer Neopam 1Gm Injection.

Medicinal Benefits

Neopam 1Gm Injection contains Pralidoxime, a cholinesterase reactivator that belongs to the oxime class of drugs. Pralidoxime is together with another medicine called atropine to treat poisoning caused by organic phosphorus pesticides (such as diazinon, malathion, sarin and parathion). Pralidoxime injection is also used to treat an overdose of medicines (such as neostigmine, ambenonium, and pyridostigmine) that treat myasthenia gravis. It works by reactivating the enzymes (cholinesterase) blocked by many pesticides or medicines. Poisoning with these substances or drugs weakens your muscles, including those that let you breathe. Pralidoxime is used to help you regain muscle strength.

How Neopam 1Gm Injection Works

Neopam 1Gm Injection contains Pralidoxime, a cholinesterase reactivator. It works by reactivating the enzyme cholinesterase (mainly outside the central nervous system), which has been inactivated by phosphorylation due to an organophosphate pesticide or related compound.

Storage

Store in a cool and dry place away from sunlight
Side effects of Neopam 1Gm Injection
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

What if I have taken an overdose of Neopam 1Gm Injection

As Neopam 1Gm Injection is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away.

Drug Warnings

Neopam 1Gm Injection is not recommended as an antidote for carbamate pesticide overdose since it may enhance carbaryl toxicity or known hypersensitivity to the drug. Before taking Neopam 1Gm Injection, inform your doctor of all your medical problems, sensitivities, and medicines. Also, let your doctor know if you are pregnant, want to become pregnant, or are breastfeeding. Do not drive or operate machinery because Neopam 1Gm Injection may cause diplopia (double vision), decreased accommodation, and dizziness.

Drug-Drug Interactions

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PralidoximePramlintide
Critical

Drug-Drug Interactions

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PralidoximePramlintide
Critical
How does the drug interact with Neopam 1Gm Injection:
Neopam 1Gm Injection and Pramlintide when used together may enhance the effects of the other, which may increase the risk of side effects. .

How to manage the interaction:
Co-administration of Neopam 1Gm Injection with Pramlintide is not recommended as it can possibly result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

ANTIDOTES
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Alcohol

Caution

Avoid consuming alcohol. Consult your doctor for more information.

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Pregnancy

Caution

Inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Neopam 1Gm Injection.

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Breast Feeding

Caution

Caution is advised. Let your doctor know if you are a nursing mother before taking Neopam 1Gm Injection; your doctor may suggest stopping breastfeeding for a certain period.

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Driving

Unsafe

Neopam 1Gm Injection may cause blurred vision and diplopia (double vision). It impacts your ability to drive or operate machinery.

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Liver

Caution

Inform your doctor before receiving Neopam 1Gm Injection if you have had a liver impairment/disorder history. Your doctor will weigh the benefits and potential risks before prescribing Neopam 1Gm Injection.

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Kidney

Caution

Caution should be exercised. Inform your doctor before receiving Neopam 1Gm Injection if you have had a kidney impairment/disorder history. Your doctor will weigh the benefits and potential risks before prescribing Neopam 1Gm Injection.

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Children

Consult your doctor

Please consult your doctor. The doctor will decide the dose based on your child's age and condition.

Have a query?

FAQs

Neopam 1Gm Injection is used treat Organophosphate poisoning.

Neopam 1Gm Injection contains Pralidoxime, a cholinesterase reactivator. It works by reactivating the enzyme cholinesterase (mainly outside the central nervous system), which has been inactivated by phosphorylation due to an organophosphate pesticide or related compounds and medicines.

Neopam 1Gm Injection is an antidote Antidote for organophosphorus nerve agent poisoning, including chlorosarin, cyclosarin (GF), R-VX, tabun (GA), sarin (GB), VX, soman (GD), chlorosoman and organophosphorus pesticides.

Pralidoxime injection is also used to treat an overdose of medicines (such as neostigmine, ambenonium, and pyridostigmine) that treat myasthenia gravis.

The common side effects of Neopam 1Gm Injection may include mild to moderate pain at the site of injection, blurred vision, diplopia (double vision), impaired accommodation, dizziness, headache, drowsiness, nausea, tachycardia (fast heartbeat), increased systolic and diastolic blood pressure, hyperventilation (rapid or deep breathing), and muscular weakness. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, inform your doctor.

Neopam 1Gm Injection is a cholinesterase reactivator that belongs to the oxime class of drugs. It is used to treat poisoning caused by organic phosphorus pesticides or chemicals, often in combination with atropine.

Neopam 1Gm Injection is typically administered intravenously (through a vein) or intramuscularly (into a muscle). It is usually given in a hospital setting by a healthcare professional. The administration route and dosage may vary depending on the specific situation and medical guidance.

Country of origin

India

Manufacturer/Marketer address

Troikaa Pharmaceuticals Ltd., Registered Office: , 'Commerce House - 1', Satya Marg, Bodakdev, Ahmedabad-380 054. Gujarat, India.
Other Info - NEO0249

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