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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy

Nicip Plus Tablet is used to relieve pain in conditions like osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and dysmenorrhea. Besides this, it is also useful for dental pain, muscle pain, back pain, ear pain, and throat pain. It contains Nimesulide and Paracetamol, which works by blocking the effect of prostaglandins, a chemical responsible for inducing pain and inflammation in the body. It also lowers the elevated body temperature by promoting heat loss (through sweating), which helps reset the hypothalamic thermostat. Thus, it helps relieve pain. It may cause common side effects such as loss of appetite (in case of liver condition), nausea, vomiting, abdominal pain, persistent tiredness or dark/discoloured urine.

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Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Nicip Plus Tablet

Nicip Plus Tablet belongs to a class of painkillers called non-steroidal anti-inflammatory drugs (NSAIDs) used to relieve pain in conditions like osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and dysmenorrhea. Besides this, it is also useful for dental pain, muscle pain, back pain, ear pain, and throat pain. 

Nicip Plus Tablet is composed of two medicines: Nimesulide and Paracetamol. Nicip Plus Tablet works by blocking the effect of prostaglandins, a chemical responsible for inducing pain and inflammation in the body. It also lowers the elevated body temperature by promoting heat loss (through sweating), which helps reset the hypothalamic thermostat. Together, Nicip Plus Tablet helps relieve pain.

Take Nicip Plus Tablet exactly as directed by your doctor. The most common side effects of Nicip Plus Tablet are loss of appetite (in case of liver condition), nausea, vomiting, abdominal pain, persistent tiredness or dark/discoloured urine. It is not necessary for everyone to experience the above side effects. In case of any discomfort, speak with your doctor.

Do not take Nicip Plus Tablet if you are allergic to painkillers like aspirin, ibuprofen, naproxen or diclofenac. It is not recommended for use in children, people with liver disease, heart disease or gastric ulcers/bleeding problems. Nicip Plus Tablet may be associated with a small increase in heart attack risk (myocardial infarction). Avoid alcohol consumption as it may damage your liver and cause increased side effects on taking this medicine. Consult your doctor if your pain, inflammation and fever symptoms do not disappear even after ten days.

Uses of Nicip Plus Tablet

Nicip Plus Tablet is used to provide pain relief. The detailed uses of Nicip Plus Tablet are as follows:
• Pain Relief: Nicip Plus Tablet relieves mild to moderate pain, such as headaches, muscle aches, and joint pain.
• Fever Reduction: Nicip Plus Tablet helps to reduce fever, relieving discomfort caused by high body temperature.
• Arthritis Management: Nicip Plus Tablet is involved in managing arthritis symptoms by reducing pain and inflammation.
• Post-operative Care: Nicip Plus Tablet helps to manage post-operative pain, making recovery more comfortable after surgery.
• Chronic Pain Conditions: Nicip Plus Tablet provides relief for chronic pain conditions, helping when other treatments may not be enough.
• Respiratory Infection Relief: Nicip Plus Tablet is also used to alleviate pain, fever, and inflammation associated with respiratory infection.

Directions for Use

Swallow the medicine as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Nicip Plus Tablet comprises nimesulide and paracetamol, primarily used to treat mild to moderate pain. Nicip Plus Tablet is prescribed mainly to treat pain and relieve discomfort caused by conditions like tooth pain, arthritis, period pain and other types of short-term pains. It helps treat pain by blocking the chemical messenger in the brain responsible for causing fever, pain and inflammation. Nimesulide works by blocking the effect of a chemical known as prostaglandin, responsible for inducing pain and inflammation in our body. On the other hand, Paracetamol lowers the elevated body temperature and mild pain by inhibiting prostaglandin synthesis by promoting heat loss (through sweating) that helps reset the hypothalamic thermostat. Paracetamol has the advantage of producing less gastric irritation than other painkillers like aspirin.

How Nicip Plus Tablet Works

Nicip Plus Tablet is composed of two medicines: Nimesulide and Paracetamol. Nicip Plus Tablet works by blocking the effect of prostaglandins, a chemical responsible for inducing pain and inflammation in the body. It also lowers the elevated body temperature by promoting heat loss (through sweating), which helps reset the hypothalamic thermostat. Together, Nicip Plus Tablet helps relieve pain.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Nicip Plus Tablet

Do not take more than the prescribed dose of Nicip Plus Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Nicip Plus Tablet is contraindicated in patients with a history of hypersensitivity (allergic) reaction to Nicip Plus Tablet , paracetamol, nimesulide, or other pain killers. Please inform your doctor before starting Nicip Plus Tablet if you have an active stomach ulcer, recent gastrointestinal bleeding, asthma, recent by-pass heart surgery or severe kidney/liver impairment. Nimesulide present in Nicip Plus Tablet is known to affect fertility, so if you are planning for pregnancy, contact the doctor. Nicip Plus Tablet should be avoided in both pregnant (especially last trimester of pregnancy) and breastfeeding women, as it may pass the milk affecting the baby. Patients with heart diseases and recent stroke (bleeding in the brain) should not take Nicip Plus Tablet as a substitute for aspirin. It should not be given to children (below 12 years) with symptoms of fever and chills or suffering from influenza (flu) or chickenpox.

Drug-Drug Interactions

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ParacetamolOxazepam
Severe
ParacetamolKetoconazole
Severe

Drug-Drug Interactions

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ParacetamolOxazepam
Severe
How does the drug interact with Nicip Plus Tablet:
Co-administration of Nicip Plus Tablet may decrease the excretion rate of Oxazepam which could result in a higher serum level.

How to manage the interaction:
Although there is a possible interaction between Oxazepam and Nicip Plus Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ParacetamolKetoconazole
Severe
How does the drug interact with Nicip Plus Tablet:
Co-administration of Nicip Plus Tablet and Ketoconazole may increase the risk of liver injury.

How to manage the interaction:
Although there is a possible interaction between Nicip Plus Tablet and Ketoconazole, you can take these medicines together if prescribed by a doctor. However, if you have joint pain or swelling, fever, chills, unusual bleeding or bruising, skin rash, itching, over-tiredness, nausea, vomiting, loss of appetite, stomach pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact a doctor immediately as these may be signs and symptoms of liver damage. Do not discontinue the medication without consulting a doctor.
ParacetamolLomitapide
Severe
How does the drug interact with Nicip Plus Tablet:
Co-administration of Lomitapide and Nicip Plus Tablet may increase the risk of severity of liver injury.

How to manage the interaction:
Although there is a possible interaction between Nicip Plus Tablet and Lomitapide, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ParacetamolMipomersen
Severe
How does the drug interact with Nicip Plus Tablet:
Co-administration of Mipomersen with Nicip Plus Tablet may increase the risk or severity of liver injury.

How to manage the interaction:
There may be a possibility of interaction between Nicip Plus Tablet and Mipomersen, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
ParacetamolValdecoxib
Severe
How does the drug interact with Nicip Plus Tablet:
Co-administration of Nicip Plus Tablet and Valdecoxib may increase the risk or severity of adverse effects.

How to manage the interaction:
Although there is a possible interaction between Nicip Plus Tablet and Valdecoxib, you can take these medicines together if prescribed by a doctor. However, if the side effects worsen, please consult a doctor.
ParacetamolTeriflunomide
Severe
How does the drug interact with Nicip Plus Tablet:
Co-administration of Teriflunomide with Nicip Plus Tablet may increase the risk or severity of Liver problems.

How to manage the interaction:
Taking Nicip Plus Tablet with Teriflunomide together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
ParacetamolLeflunomide
Severe
How does the drug interact with Nicip Plus Tablet:
Co-administration of Nicip Plus Tablet and Leflunomide may increase the risk of liver problems.

How to manage the interaction:
Although there is a possible interaction between Nicip Plus Tablet and Leflunomide, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ParacetamolKetamine
Severe
How does the drug interact with Nicip Plus Tablet:
Co-administration of ketamine and Nicip Plus Tablet may decrease the effectiveness of Ketamine which could result in a higher blood level.

How to manage the interaction:
Although taking Ketamine and Nicip Plus Tablet together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you're feeling very sleepy or having trouble breathing, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include more glucosamine, chondroitin sulphate, vitamin D, and calcium-enriched supplements. Besides this, turmeric and fish oils can help reduce inflammation in the tissue.
  • Please do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching low,, impact aerobic exercises like walking on a treadmill, bike riding and swimming. You can also strengthen your muscles by lifting light weights.
  • In chronic arthritis or joint pain conditions, fish like salmon, trout, tuna and sardines. These fishes are enriched with omega-3 fatty acids that minimize chemical cytokines, which ramp up inflammation.
  • Your sitting posture is important, especially when you have pain and inflammation. Try to sit as little as possible and only for a short time. Long-term immobility is harmful in conditions like arthritis. Use back support like a rolled-up towel to minimise pain at the back of your spine curve. Keep your knees and hips at a right angle. Besides this, you can also use a footrest if required.

Habit Forming

No

Therapeutic Class

ANALGESIC AND ANTIPYRETIC AGENT

Nicip Plus Tablet Substitute

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Alcohol

Caution

Taking Nicip Plus Tablet with alcohol may cause dizziness or drowsiness. Besides this, it can also damage your liver if taken for a longer duration. So, avoid or limit the intake of alcoholic beverages with Nicip Plus Tablet .

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Pregnancy

Unsafe

Use of Nicip Plus Tablet during pregnancy is not recommended as taking this medicine during the last 3 months of pregnancy may harm the unborn baby. Consult your doctor for further advice.

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Breast Feeding

Unsafe

Use of Nicip Plus Tablet during breastfeeding is not recommended as it may pass through the milk and harm the baby. Consult your doctor for further advice.

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Driving

Caution

After taking Nicip Plus Tablet , you may notice dizziness, sleepiness, drowsiness. So, you should stop taking Nicip Plus Tablet and contact your doctor.

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Liver

Caution

Nicip Plus Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Nicip Plus Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Caution

Nicip Plus Tablet is contraindicated in children below 20 kg body weight or younger than 6 years of age. It may cause kidney problems in children and adolescents who are dehydrated.

Have a query?

FAQs

Nicip Plus Tablet is used to relieve pain in conditions like osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and dysmenorrhea. Besides this, it is also useful for dental pain, muscle pain, back pain, ear pain, and throat pain.

Nicip Plus Tablet works by blocking the effect of prostaglandins, a chemical responsible for inducing pain and inflammation in the body. It also lowers the elevated body temperature by promoting heat loss (through sweating), which helps reset the hypothalamic thermostat. Together, Nicip Plus Tablet helps relieve pain.

No, Nicip Plus Tablet is not indicated for stomach pain. If you have stomach pain post-ingestion, it may be a sign of stomach ulcer or gastric bleeding. Do not take Nicip Plus Tablet in this condition. It is better to inform your doctor in case of stomach pain post-ingestion of this medication.

No, Nicip Plus Tablet should not be taken as a long-term medication as it may lead to stomach ulcers/bleeding and kidney problems. For best results, take it in the doses and duration advised by your doctor.

Yes, Nicip Plus Tablet should preferably be taken with food to avoid an upset stomach. If taken on an empty stomach, it may cause stomach irritation and an upset stomach.

You should not take Nicip Plus Tablet if you have a history of peptic ulceration, a history of gastrointestinal haemorrhage, Crohn's disease or ulcerative colitis.

No, Nicip Plus Tablet should not be taken if you plan to get pregnant, as it contains nimesulide, which may cause birth defects. So, before starting Nicip Plus Tablet , please consult your doctor if you are pregnant or planning pregnancy.

Though Nicip Plus Tablet may be used for tooth pain, it should not be used in children unless advised by the doctor. Please consult the doctor before using Nicip Plus Tablet in children; the doctor will prescribe appropriate medicine based on the child’s condition.

Nicip Plus Tablet is a combination medication that belongs to the class of painkillers called non-steroidal anti-inflammatory drugs. It is mainly prescribed to treat pain and relieve discomfort caused by tooth pain, arthritis, period pain, and other types of short-term pain.

As Nicip Plus Tablet is indicated for short-term pain relief, it can be discontinued if the pain is relieved. However, it is advised to take Nicip Plus Tablet for the prescribed duration to treat your condition effectively.

Taking Nicip Plus Tablet may cause nausea and vomiting. If you feel sick, talk to your doctor or pharmacist for help. To cope with nausea and vomiting, take your medicine with food or milk, eat small meals, and stay hydrated. Avoid spicy foods and lying down after taking the medicine. Try ginger products like ginger tea or candies. If your symptoms are severe, ask your doctor for help.

Don't take Nicip Plus Tablet if you're allergic to it or other painkillers, have stomach ulcers or bleeding, asthma, recent heart surgery, severe kidney or liver problems. Consult the doctor if you are pregnant or breastfeeding.

Nicip Plus Tablet can be taken with vitamin B-complex if prescribed by your doctor. Please consult your doctor if you have any concerns.

Nicip Plus Tablet may cause harm to the liver, especially if used for a longer duration or in higher doses. So, do not take a higher dose than the recommended dose of Nicip Plus Tablet .

Taking more than the recommended dose of Nicip Plus Tablet is dangerous. Overuse of Nicip Plus Tablet can harm your liver and kidneys, which can be life-threatening. Always follow the dosage instructions as advised by the doctor.

Nicip Plus Tablet should be stored in a cool and dry place away from the sunlight. Keep away from children and pets.

Though Nicip Plus Tablet may help lower body temperature, it is primarily used in the treatment of pain relief. Consult your doctor before taking Nicip Plus Tablet for fever or if you have any concerns.

Follow your doctor's advice and take the right amount of medicine. Inform your doctor about any health problems, allergies, or other drugs you're taking. Be aware of side effects and take care of yourself. If you're pregnant while on treatment, inform your doctor immediately. Don't take other medications unless instructed by the doctor. Alcohol consumption should be avoided. By following these precautions, you'll benefit most from your medicine and stay safe.

You are recommended to consult your doctor before taking other medications while using Nicip Plus Tablet to avoid drug interactions.

If you suspect an overdose of Nicip Plus Tablet , seek medical help immediately. Quick action can help prevent serious harm, so don’t wait to seek medical attention.

The common side effects of Nicip Plus Tablet include loss of appetite, nausea, vomiting, abdominal pain, persistent tiredness, or dark or discolored urine. Everyone doesn't need to experience the above side effects. In case of any discomfort, speak with your doctor.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - NIC0031

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