Do not take Nifty-SR Tablet 10's if you are allergic or have had a severe reaction to Nifty-SR Tablet 10's or any other medicines in the past, or inherited conditions such as porphyria (a blood disorder), glucose-6-phosphate dehydrogenase (G6PD) deficiency,  severe kidney disease, diabetes, or any illness-causing severe weakness, anaemia or vitamin B deficiency. Inform your doctor if you have or have ever had a kidney, heart, or lung transplant, a joint or tendon disorder such as rheumatoid arthritis (an autoimmune disorder of joints causing pain, swelling, and loss of function), seizures (fits), epilepsy or if you participate in regular physical activity. Taking Nifty-SR Tablet 10's may worsen muscle weakness in people with myasthenia gravis (a nervous system disorder that causes muscle weakness) and cause severe difficulty breathing or death. Grapefruit, a calcium-rich food, should be avoided along with Nifty-SR Tablet 10's. And also, exposure to sunlight should be avoided while taking Nifty-SR Tablet 10's as it may cause increased phototoxicity or photosensitivity. Patients with epilepsy and irregular heartbeat (QT prolongation) should tell their doctor before taking Nifty-SR Tablet 10's.

Drug-Drug interactions: Nifty-SR Tablet 10's may have an interaction with Vaccines [such as Bacillus Calmette-Guerin (BCG),  cholera vaccine, live, typhoid vaccine, live], a medicine used to treat relapsing forms of multiple sclerosis (teriflunomide), medications to treat rheumatoid arthritis (leflunomide), cholesterol-lowering medications (lomitapide), cholesterol-lowering pills (mipomersen), medication is used to treat a certain type of tumour (pexidartinib), a topical anaesthetic (prilocaine), and medicine used to treat relapsing forms of multiple sclerosis (teriflunomide).

Drug-Food Interactions:  Nifty-SR Tablet 10's interacts with grapefruit, foods rich in calcium, and a large volume of alcohol. Grapefruit contains compounds known as furanocoumarins, which interfere with how the liver and intestines break down the medicine and filter out toxins.

Drug-Disease Interactions: Inform your doctor if you have or have ever had colitis (a chronic digestive disease characterized by inflammation of the inner lining of the colon), G-6-PD deficiency (hemolytic anaemia), hepatotoxicity (Liver Disease), Renal Dysfunction (kidney disease), peripheral neuropathy (weakness, numbness and pain from nerve damage), and respiratory disorders.

• It would be best to take probiotics after taking the full course of Nifty-SR Tablet 10's to restore some healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
• Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria which helps stimulate their growth. Thus fibre foods may help restore healthy gut bacteria after taking a course of antibiotics. Whole grains like whole-grain bread, and brown rice, should be included in your diet.
• Avoid taking too much calcium enriched foods and drinks as it might affect the working of Nifty-SR Tablet 10's.
• Avoid intake of alcoholic beverages with Nifty-SR Tablet 10's as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the Nifty-SR Tablet 10's in fighting off infections.