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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Nirhes Injection belongs to the group of medications called plasma volume expanders. It is used to treat hypovolemia (low blood volume). It draws water into the bloodstream, increasing plasma volume and improving circulation. It helps replace lost blood volume, improving blood flow and pressure. It supports vital organ function and stability during operations or injury, reducing the risk of shock and fluid loss. The common side effects of Nirhes Injection may include itching, reduced plasma proteins, decreased hematocrit, and increased serum amylase.

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Manufacturer/Marketer :

Aculife Healthcare Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Nirhes Injection

Nirhes Injection is used to treat low blood volume (hypovolemia). Hypovolemia is a condition in which the body has low blood volume, usually due to excessive fluid loss from bleeding, dehydration, or severe burns. If untreated, it can lead to low blood pressure, poor organ oxygen delivery, and potential shock. The treatment involves fluid replacement with crystalloids or colloids to restore circulation.

Nirhes Injection contains Hydroxyethyl starch. It draws water into the bloodstream, increasing plasma volume and improving circulation. In cases of low blood volume (hypovolemia), it helps maintain blood pressure and organ perfusion. Its effects are temporary and depend on dose, molecular weight, and infusion rate.

The dose and duration of treatment with Nirhes Injection may vary depending on your medical condition. Common side effects include itching, reduced plasma proteins, decreased hematocrit, and increased serum amylase. Most of these side effects gradually resolve on their own. However, please consult the doctor if they persist or worsen.

Inform your doctor if you are pregnant or breastfeeding before receiving Nirhes Injection. It is unknown whether Nirhes Injection interacts with alcohol or not. However, as a precautionary measure, it is best to avoid alcohol to prevent potential risks. Inform your doctor if you have heart, kidney, or liver problems or any pre-existing health conditions and about all the medicines you are taking to minimize the risk of potential side effects.

Uses of Nirhes Injection

Nirhes Injection is used to treat hypovolemia (low blood volume). The detailed use of Nirhes Injection is as follows:<br/>• Treats hypovolemia (low blood volume): Nirhes Injection efficiently restores blood volume, improves circulation, and aids in blood pressure regulation. This is necessary in cases involving surgery, trauma, or extreme blood loss.<br/>

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.• Nirhes Injection should be administered by a nurse or doctor to ensure proper dosage, technique, and monitoring for any potential side effects or complications.• Do not self-administer.

Medicinal Benefits

Nirhes Injection belongs to the group of medications called plasma volume expanders and is used to treat hypovolemia. It helps replace lost blood volume, improving blood flow and pressure. It supports vital organ function and stability during operations or injury, reducing the risk of shock and fluid loss.

How Nirhes Injection Works

Nirhes Injection contains Hydroxyethyl starch. It works by drawing water into the bloodstream, increasing plasma volume, and improving circulation. It helps maintain blood pressure and organ perfusion in cases of hypovolemia (low blood volume).

Storage

• Store in a cool and dry place away from sunlight.
• Keep Nirhes Injection out of the sight and reach of children.
• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Nirhes Injection

Since Nirhes Injection will be administered by the doctor or nurse, the risk of overdose is minimal or low. However, in cases of accidental overdose, immediate medical attention is necessary. Overdose may cause circulatory system overload, leading to complications such as pulmonary oedema, high blood pressure, and fluid retention. Close monitoring and prompt treatment are essential to prevent serious adverse effects.

Drug Warnings

Inform your doctor if you have cardiac insufficiency, severe kidney dysfunction, or electrolyte imbalances, as the fluid overload risk is higher. Fluid status and infusion rates should be carefully monitored. In severe dehydration, a crystalloid should be given first. Patients undergoing open-heart surgery should be closely observed, as Nirhes Injection may increase bleeding risk. Coagulation status should be monitored, and use should be discontinued if coagulopathy occurs. High doses of Nirhes Injection may affect blood clotting, haematocrit, and plasma proteins. Liver function should be checked due to potential amylase elevation. If you experience hypersensitivity reactions, including anaphylaxis, stop using Nirhes Injection immediately. Avoid using Nirhes Injection in patients with pre-existing renal dysfunction and discontinue immediately if renal injury occurs. Monitor kidney function for at least 90 days, as kidney replacement therapy may be required. Prolonged use of Nirhes Injection may cause severe and persistent itching. Its use in children is limited and should only be under strict medical supervision, with individualized dosage for newborns and premature infants. Inform your doctor if you are pregnant, breastfeeding, or taking other medications to prevent potential interactions.

Diet & Lifestyle Advise

  • Drink plenty of water and electrolyte-rich fluids to stay hydrated.
  • Consume electrolyte-rich foods like bananas (potassium), avocados (potassium), and nuts (magnesium).
  • Avoid excessive intake of caffeine.
  • Watch for rapid heartbeat, dizziness, or low blood pressure and seek medical help.
  • Rest and refrain from strenuous activities.
  • Get enough sleep and practice stress-reducing techniques like meditation or deep breathing.

Habit Forming

No

Therapeutic Class

BLOOD SUBSTITUTES AND PLASMA EXPANDERS
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Alcohol

Consult your doctor

It is unknown whether alcohol interacts with Nirhes Injection. However, avoid alcohol consumption while treatment with Nirhes Injection as a precautionary measure to prevent unpleasant side effects.

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Pregnancy

Consult your doctor

There are no adequate and well-controlled studies in pregnant women. Please, inform your doctor before using this medication during pregnancy.

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Breast Feeding

Consult your doctor

It is unknown whether Nirhes Injection passes into breastmilk. Please consult your doctor if you are breastfeeding to evaluate the potential risks and benefits.

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Driving

Consult your doctor

Nirhes Injection is not known to cause dizziness. However, please consult your doctor if you experience dizziness for further evaluation and guidance.

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Liver

Caution

Nirhes Injection is not recommended in patients with severe liver diseases. Please consult your doctor if you have any concerns.

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Kidney

Caution

Nirhes Injection is not recommended in patients with renal impairment experiencing oliguria or anuria unless caused by hypovolemia. Please consult your doctor if you have any concerns.

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Children

Caution

There is limited information on its use in children, and it should only be administered under close medical supervision. Dosage will be individualized, especially for newborns and premature infants. Please consult the doctor for guidance.

Have a query?

FAQs

Nirhes Injection belongs to the group of medications called plasma volume expanders used to treat hypovolemia (low blood volume).

Nirhes Injection contains Hydroxyethyl starch. It works by drawing water into the bloodstream, increasing plasma volume and improving circulation. It helps maintain blood pressure and organ perfusion in cases of hypovolemia (low blood volume). Its effects are temporary and depend on dose, molecular weight, and infusion rate.

Contact your doctor if you experience allergic reactions such as headache, fever, abnormal heartbeat, or breathing issues. Seek medical attention for unusual bruising or bleeding, as these may indicate serious side effects. Additionally, report any other unexpected symptoms to your doctor.

The common side effects of Nirhes Injection include itching, reduced plasma proteins, decreased haematocrit, and increased serum amylase. Most of these side effects gradually resolve on their own over time. However, please consult the doctor if these side effects persist or worsen.

Store Nirhes Injection at 15°C–25°C and do not freeze. Keep it out of sight and reach of children.

Country of origin

India
Other Info - NI44852

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