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Nirmacom Tablet Kit (2+1) is used to treat COVID-19 (coronavirus). It contains Nirmatrelvir and Ritonavir which works by preventing the virus from replicating within the cells, which helps to stop its spread in the body. In some cases, this medicine may cause side effects such as headache, diarrhoea, nausea, vomiting, dysgeusia (change in taste) and muscle pain. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By ,
Reviewed By Praneetha Akunuri , M.Pharmacy
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More about the Product

Manufacturer/Marketer :

Hetero Healthcare Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Nirmacom Tablet Kit (2+1)

Nirmacom Tablet Kit (2+1) is primarily used to treat COVID-19, an infectious disease mainly affecting the respiratory system. COVID-19 (Coronavirus), also known as SARS-CoV-2 (Severe Acute Respiratory Syndrome Corona Virus 2), is an infectious disease caused by the coronavirus.

Nirmacom Tablet Kit (2+1) contains Nirmatrelvir and Ritonavir. These drugs belong to the protease inhibitor class. They work by inhibiting the virus's ability to replicate inside cells, preventing the spread of new viruses. As a result, Nirmacom Tablet Kit (2+1) reduces the viral presence in the body, helping to manage and treat the infection.

Take Nirmacom Tablet Kit (2+1) as prescribed by your doctor. You are advised to take Nirmacom Tablet Kit (2+1) for as long as your doctor has prescribed it for you based on your medical condition. In some cases, Nirmacom Tablet Kit (2+1) may cause diarrhoea, nausea, vomiting, abdominal pain and dysgeusia (change in taste). Most of these side effects of Nirmacom Tablet Kit (2+1) do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Please do not take Nirmacom Tablet Kit (2+1) if you are allergic to any of its ingredients. Seek medical advice before taking Nirmacom Tablet Kit (2+1) if you are pregnant or breastfeeding. Nirmacom Tablet Kit (2+1) is not recommended for children and teenagers below 18 years as safety and effectiveness have not been established. Keep your doctor informed about your health condition and medicines to rule out any side effects/interactions.

Uses of Nirmacom Tablet Kit (2+1)

Nirmacom Tablet Kit (2+1) is used in the treatment of COVID-19 (coronavirus). The detailed use of Nirmacom Tablet Kit (2+1) is as follows:

  • Treatment of COVID-19:Nirmacom Tablet Kit (2+1) is utilized to treat mild to moderate COVID-19 in patients at high risk of progressing to severe illness. This helps to reduce the risk of hospitalization and death from COVID-19.

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Directions for Use

  • Nirmacom Tablet Kit (2+1) can be taken with or without food, as food does not affect its absorption or effectiveness.
  • Nirmacom Tablet Kit (2+1) is usually taken twice a day, or as prescribed by your doctor.
  • Swallow Nirmacom Tablet Kit (2+1) as a whole with a glass of water.
  • Do not break, chew or crush Nirmacom Tablet Kit (2+1).

Key Benefits

Nirmacom Tablet Kit (2+1) belongs to a class of drugs called antiviral medications primarily used to treat COVID-19 (coronavirus). Nirmacom Tablet Kit (2+1) works by preventing the virus from replicating within the cells, which helps to stop its replication in the body. As a result, Nirmacom Tablet Kit (2+1) lowers the viral infection in the body.

How Nirmacom Tablet Kit (2+1) Works

Nirmacom Tablet Kit (2+1) is a combination of Nirmatrelvir and Ritonavir. Nirmatrelvir works by inhibiting an enzyme (SARS-CoV-2-3CL protease) essential for the coronavirus replication process. Thereby it prevents the production of the new virus. Ritonavir improves the efficacy of nirmatrelvir by decreasing its metabolism, allowing it to stay in the body for longer and at higher levels. Together, they help to treat coronavirus.

Storage

Store in a cool and dry place away from sunlight
Side effects of Nirmacom Tablet Kit (2+1)
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.

What if I have taken an overdose of Nirmacom Tablet Kit (2+1)

Take Nirmacom Tablet Kit (2+1) only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Please do not take Nirmacom Tablet Kit (2+1) if you are allergic to any of its ingredients or if you have severe liver disease. Inform your doctor if you have kidney disease, haemophilia, hepatotoxicity, hyperglycemia, hyperlipidemia, liver problems, heart problems, or if you are taking any other medicines. Consult your doctor before taking Nirmacom Tablet Kit (2+1) if you are pregnant and breastfeeding; your doctor will prescribe only if the benefits outweigh the risks. Nirmacom Tablet Kit (2+1) can reduce the effectiveness of medications used to manage HIV. Nirmacom Tablet Kit (2+1) should not be given to children below 18 years old as safety and effectiveness have not been established. Tell your doctor about your health condition and medicines to avoid side effects.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Nirmacom Tablet Kit (2+1):
Taking Phenobarbital with Nirmacom Tablet Kit (2+1) may significantly reduce the blood levels of Nirmacom Tablet Kit (2+1).

How to manage the interaction:
Taking Phenobarbital with Nirmacom Tablet Kit (2+1) is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. If you notice any unusual symptoms consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Nirmacom Tablet Kit (2+1):
Co-administration of Eplerenone and Nirmacom Tablet Kit (2+1) may significantly increase the blood levels of Eplerenone.

How to manage the interaction:
Taking Nirmacom Tablet Kit (2+1) and Eplerenone together is not recommended as it can lead to an interaction. However, it can be taken if a doctor advises it. If you experience any unusual symptoms like headaches, irritation, confusion, edema (swelling caused by too much fluid accumulation), weakness, palpitations, or constipation, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Nirmacom Tablet Kit (2+1):
Taking Nirmacom Tablet Kit (2+1) and Tolvaptan may significantly increase the blood levels of tolvaptan.

How to manage the interaction:
Taking Tolvaptan with Nirmacom Tablet Kit (2+1) is not recommended as it can possibly result in an interaction, it can be taken if a doctor has advised it. If you notice any of these symptoms like difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, fits, contact a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Nirmacom Tablet Kit (2+1):
Coadministration of Silodosin with Nirmacom Tablet Kit (2+1) can significantly increase the blood levels and effects of Silodosin, and this may cause low blood pressure and increase heart rate, especially when you rise from a sitting or lying position.

How to manage the interaction:
Taking Nirmacom Tablet Kit (2+1) and Silodosin together is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, heart palpitation-call a doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Nirmacom Tablet Kit (2+1):
When Voriconazole is taken with Nirmacom Tablet Kit (2+1), the amount of Voriconazole in the blood may decrease.

How to manage the interaction:
Taking Voriconazole with Nirmacom Tablet Kit (2+1) is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Nirmacom Tablet Kit (2+1):
Taking Methylergometrine with Nirmacom Tablet Kit (2+1) can significantly increase the blood levels and effects of methylergometrine.

How to manage the interaction:
Taking Methylergometrine with Nirmacom Tablet Kit (2+1) is not recommended, but can be taken together if prescribed by a doctor. In case you experience any side effects like severe abdominal discomfort, nausea, vomiting, tingling or numbness, weakness or pain in the muscles, pale skin, blue or purple discoloration on fingers or toes, tightness or pain in the chest, irregular heartbeat, intense headache, breathing difficulties, confusion, or slurred speech, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Nirmacom Tablet Kit (2+1):
Coadministration of Nirmacom Tablet Kit (2+1) and Sildenafil may significantly increase the blood levels of sildenafil.

How to manage the interaction:
Taking Sildenafil with Nirmacom Tablet Kit (2+1) together is generally avoided as it can possibly result in an interaction, it can be taken only if your doctor has advised it. If you notice any of these symptoms like nausea, shortness of breath, dizziness, lightheadedness, fainting, visual disturbances, ringing in the ears, vision or hearing loss, chest pain or tightness, irregular heartbeat, and/or priapism (prolonged and painful erection unrelated to sexual activity), contact a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Nirmacom Tablet Kit (2+1):
Taking Ticagrelor with Nirmacom Tablet Kit (2+1) may significantly increase the blood levels of Ticagrelor.

How to manage the interaction:
Taking Ticagrelor with Nirmacom Tablet Kit (2+1) is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Nirmacom Tablet Kit (2+1):
When Lovastatin is taken with Nirmacom Tablet Kit (2+1), it may increase the risk of side effects such as liver damage.

How to manage the interaction:
Taking Nirmacom Tablet Kit (2+1) and Lovastatin not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. If you notice any of these symptoms like muscle pain, tenderness, or weakness fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes contact a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Nirmacom Tablet Kit (2+1):
The combination of Amiodarone and Nirmacom Tablet Kit (2+1) may significantly increase the blood levels of Amiodarone.

How to manage the interaction:
Despite the fact that Amiodarone and Nirmacom Tablet Kit (2+1) interact, it can be taken if prescribed by a doctor. If you get dizziness, shortness of breath, weakness, or chest tightness, consult a doctor. Do not stop taking any medications without visiting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Drink plenty of fluids, such as water, herbal teas, and beverages, to stay hydrated and loosen mucus.
  • Include a balanced diet with fruits, vegetables, lean proteins, and whole grains to support immune function.
  • Always remember to wear a mask when you're around other people. Masks help prevent the spread of illness.
  • Keep a social distance and avoid social gatherings.
  • Do not touch your eyes, nose or mouth if your hands are not clean.
  • Hands should be washed with soap and water or an alcohol-based sanitiser on a regular basis.
  • Gargling with salt water and inhaling steam would be beneficial.

Habit Forming

No

Therapeutic Class

[ANTIVIRALS]

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Alcohol

Caution

The interaction of Nirmacom Tablet Kit (2+1) with alcohol is unknown. Please consult a doctor before consuming alcohol while using Nirmacom Tablet Kit (2+1).

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Pregnancy

Caution

If you are pregnant or planning to become pregnant, please seek medical advice. Pregnant women are only given Nirmacom Tablet Kit (2+1) if their doctor believes the benefits outweigh the risks.

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Breast Feeding

Caution

If Nirmacom Tablet Kit (2+1) is prescribed during breastfeeding, the doctor may advise you to stop breastfeeding as this medicine can pass into breast milk.

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Driving

Caution

Limited information is available about using Nirmacom Tablet Kit (2+1) while driving, so please consult a doctor if you have any concerns.

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Liver

Caution

Nirmacom Tablet Kit (2+1) should be used with caution, especially if you have a history of liver disease or condition. Please seek medical advice. Avoid taking Nirmacom Tablet Kit (2+1) if you have severe liver problems.

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Kidney

Caution

Take Nirmacom Tablet Kit (2+1) with caution, especially if you have a history of kidney diseases/conditions. The dose may be adjusted by your doctor as required. Avoid taking Nirmacom Tablet Kit (2+1) if you have severe kidney problems.

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Children

Caution

Nirmacom Tablet Kit (2+1) is not recommended for children and adolescents below 18 years as safety and effectiveness have not been established.

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Heart

Please inform your doctor if you have heart problems before taking Nirmacom Tablet Kit (2+1), as there is limited information available on its safety in such cases.

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Geriatrics

Caution

Please inform your doctor if you are geriatric before taking Nirmacom Tablet Kit (2+1), as there is limited information available on its safety in this age group.

FAQs

Nirmacom Tablet Kit (2+1) belongs to a class of drugs called antiviral medications, which are primarily used to treat COVID-19. SARS-CoV-2 is the virus that causes COVID-19, a respiratory disease that can produce mild to severe symptoms.

Nirmacom Tablet Kit (2+1) works by preventing the virus from replicating within the cells, which helps to stop its spread in the body. Thereby it prevents the production of the new virus.

If you miss a dose within 8 hours of your usual time, take it as soon as you remember. If more than 8 hours have passed, skip the missed dose and continue with your regular dosing schedule. Do not take two doses simultaneously to make up for a missed dose.

Inform your doctor if you are taking Atorvastatin. Combining these drugs may elevate atorvastatin levels in the blood. This increases the chance of side effects such as liver damage and rhabdomyolysis, an uncommon but deadly illness characterised by the breakdown of skeletal muscle tissue.

You are recommended to inform your doctor before taking any other medicines with Nirmacom Tablet Kit (2+1). Your doctor will notify you regarding medicines that should not be taken along with Nirmacom Tablet Kit (2+1).

Nirmacom Tablet Kit (2+1) is used with Ritonavir to help it remain in your body longer and work more effectively. It slows the breakdown of ritonavir, allowing you to experience a stronger effect from the medication. This combination helps better manage COVID-19 and improve your treatment results.

Do not stop taking Nirmacom Tablet Kit (2+1) without consulting your doctor, as it may reduce the medication’s effectiveness. To treat your condition effectively, continue taking Nirmacom Tablet Kit (2+1) for as long as prescribed by your doctor. If you experience any difficulty taking Nirmacom Tablet Kit (2+1), do not hesitate to speak with your doctor.

The side effects of Nirmacom Tablet Kit (2+1) include diarrhoea, nausea, vomiting, abdominal pain and dysgeusia (change in taste). Consult the doctor if any of these side effects persist or worsen

Country of origin

India

Manufacturer/Marketer address

2Nd Floor, 8-3-166/7/1 Erragadda, Hyderabad-500018
Other Info - NIR0141

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