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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Tamoxifen is primarily used to treat and prevent breast cancer. In order to lower the chance of cancer recurrence following surgery, chemotherapy, or radiation therapy, it is frequently administered for both early and advanced stages of breast cancer.

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Composition :

TAMOXIFEN-20MG

Consume Type :

Oral

Expires on or after :

Return Policy :

Not Returnable

About Nolvatam 20 mg Tablet

Nolvatam 20 mg Tablet is primarily used to treat breast cancer. It is also used to treat infertility caused by a failure in the ovulation (produce and release) process in women. Breast cancer is a type of cancer in the breast cells stimulated by a female sex hormone called estrogen.

Nolvatam 20 mg Tablet contains Tamoxifen, which blocks the effects of this estrogen, thus helping in treating breast cancer.

The common side effects of Nolvatam 20 mg Tablet include hot flashes, headache, muscle aches, leg cramps, tiredness, nausea, thinning of hair and numbness or tingling sensation. If you notice any side effects that are not manageable, please consult your doctor.

Do not take or stop this medicine unless the doctor advised you to do so. Nolvatam 20 mg Tablet is not indicated for use in pregnant and breastfeeding women. Nolvatam 20 mg Tablet may make you feel tired; hence, drive when you are alert only. Nolvatam 20 mg Tablet is not recommended for children below two years of age.

Uses of Nolvatam 20 mg Tablet

Nolvatam 20 mg Tablet is used in the treatment of breast cancer. The detailed uses of Nolvatam 20 mg Tablet are as follows:

  • Treats Breast Cancer: Nolvatam 20 mg Tablet is primarily used to treat breast cancer by blocking the effects of oestrogen (a hormone).
  • Treats Female Infertility Due to Ovulation Disorders: Nolvatam 20 mg Tablet is used to stimulate the release of eggs (ovulation) in women experiencing infertility caused by ovulation disorders.

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Directions for Use

  • Nolvatam 20 mg Tablet can be taken with or without food at regular intervals as prescribed by the doctor.
  • It is usually taken once or twice a day; however, follow the dosage and timing advised by the doctor.
  • Swallow Nolvatam 20 mg Tablet as a whole with a glass of water.
  • Do not chew, crush, or break it.

Key Benefits

  • Hormone-positive breast cancer is treated by slowing or stopping the proliferation of cancer cells that are dependent on estrogen.
  • Minimises the likelihood that breast cancer may return following radiation, chemotherapy, or surgery.
  • Applied to women who have other risk factors or a significant family history of the disease.
  • Patients with breast cancer may have higher survival rates after long-term use.
  • Effective for women of all ages, both premenopausal and postmenopausal.
  • Reduces symptoms and slows the progression of advanced or metastatic breast cancer.
  • Reduces breast growth brought on by hormonal imbalance in men with gynecomastia.
  • In certain infertility conditions, it may be used to induce ovulation.

How Nolvatam 20 mg Tablet Works

Nolvatam 20 mg Tablet contains Tamoxifen, which belongs to the class of 'anti oestrogens. Some types of breast cancers need oestrogen (female sex hormone) to grow. Nolvatam 20 mg Tablet blocks the effects of this oestrogen, thus helping in treating breast cancer. Nolvatam 20 mg Tablet is also used to reduce the risk of occurrence of breast cancer in women due to age and personal and family medical history.

Storage

Store in a cool and dry place away from sunlight
Side effects of Nolvatam 20 mg Tablet

What if I have taken an overdose of Nolvatam 20 mg Tablet

Take Nolvatam 20 mg Tablet only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include dizziness, unsteadiness, and uncontrolled shaking of a part of the body. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

  • Inform your doctor if you have any allergic reactions to Nolvatam 20 mg Tablet or other medications.
  • Before starting Nolvatam 20 mg Tablet , let your doctor know if you have any medical history of liver or kidney diseases, heart diseases, high cholesterol levels, high blood pressure, diabetes, history of stroke or blood clot, receiving chemotherapy, and cataracts.
  • Nolvatam 20 mg Tablet can affect the unborn baby when used in pregnancy. It may also have harmful effects on the breastfed infant when used by a lactating mother. Hence, Nolvatam 20 mg Tablet is not indicated for use in pregnancy and breastfeeding women.
  • If you are using Nolvatam 20 mg Tablet , make sure to use reliable contraception forms to prevent pregnancy during the course.
  • Nolvatam 20 mg Tablet can make you feel tired and affects your mental ability to drive.
  • Do not drive or operate machinery if you are not mentally alert and focused.
  • Avoid alcohol consumption while being treated with Nolvatam 20 mg Tablet .
  • Nolvatam 20 mg Tablet is not recommended for children younger than two years of age.

Drug-Drug Interactions

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TamoxifenSaquinavir
Critical

Drug-Drug Interactions

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TamoxifenSaquinavir
Critical
How does the drug interact with Nolvatam 20 mg Tablet:
Taking Nolvatam 20 mg Tablet with saquinavir may increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Nolvatam 20 mg Tablet with Saquinavir is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not stop using any medications without consulting doctor.
How does the drug interact with Nolvatam 20 mg Tablet:
Taking Nolvatam 20 mg Tablet with Pimozide can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Pimozide with Nolvatam 20 mg Tablet is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Nolvatam 20 mg Tablet:
Taking Nolvatam 20 mg Tablet with sparfloxacin can increase the risk of irregular heart rhythm

How to manage the interaction:
Taking Nolvatam 20 mg Tablet with Sparfloxacin is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not stop using any medications without consulting doctor.
How does the drug interact with Nolvatam 20 mg Tablet:
Taking Nolvatam 20 mg Tablet with warfarin can increase the risk of bleeding.

How to manage the interaction:
Taking Nolvatam 20 mg Tablet with Warfarin is not recommended but can be taken together if prescribed by a doctor. However, consult a doctor if you experience bleeding, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Nolvatam 20 mg Tablet:
Co-administration of Nolvatam 20 mg Tablet with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Nolvatam 20 mg Tablet with Ziprasidone together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Nolvatam 20 mg Tablet:
Taking Nolvatam 20 mg Tablet with thioridazine can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Nolvatam 20 mg Tablet with Thioridazine is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
TamoxifenDicoumarol
Critical
How does the drug interact with Nolvatam 20 mg Tablet:
Taking Nolvatam 20 mg Tablet with dicoumarol can increase the risk of bleeding.

How to manage the interaction:
Taking Nolvatam 20 mg Tablet with Dicoumarol is not recommended, but can be taken together if prescribed by a doctor. However, if you experience bleeding, vomiting, blood in your urine or stools, headache, dizziness, or weakness contact your doctor immediately. Do not discontinue any medication without consulting a doctor.
TamoxifenEdoxaban
Severe
How does the drug interact with Nolvatam 20 mg Tablet:
Taking Nolvatam 20 mg Tablet with edoxaban may increase the blood levels of edoxaban which can increase the risk of bleeding tendencies.

How to manage the interaction:
Although taking Nolvatam 20 mg Tablet and edoxaban together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Nolvatam 20 mg Tablet:
Taking mifepristone together with Nolvatam 20 mg Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although taking Nolvatam 20 mg Tablet and mifepristone together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, shortness of breath. Do not stop using any medications without consulting doctor.
How does the drug interact with Nolvatam 20 mg Tablet:
Taking efavirenz together with Nolvatam 20 mg Tablet can increase the risk of an irregular heart rhythm and other side effects.

How to manage the interaction:
Although taking Nolvatam 20 mg Tablet and efavirenz together can result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Diet changes:

  • To promote general health and recuperation throughout treatment, consume lots of fruits, vegetables, healthy grains, and lean protein.
  • Reduce your consumption of processed meals, red meat, and fried foods because they may raise your risk of heart disease and weight gain.
  • To promote bone health, eat ragi, almonds, cheese, milk, curd, and green leafy vegetables.
  • Avoid soy products and supplements in excess as they may disrupt the balance of hormones when undergoing treatment.

Lifestyle changes:

  • To keep your weight in check, boost your energy levels, and lower your chance of cancer returning, try yoga, walking, or mild exercise.
  • Excessive alcohol consumption and smoking can lower overall therapeutic benefits and raise the risk of problems.

 

Habit Forming

No

Therapeutic Class

[ANTINEOPLASTIC]

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Alcohol

Consult your doctor

It is unsafe to consume alcohol while using Nolvatam 20 mg Tablet . Please consult your doctor for more information.

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Pregnancy

Unsafe

Nolvatam 20 mg Tablet is a pregnancy category D drug. It is unsafe to use Nolvatam 20 mg Tablet in pregnancy and can have harmful effects on the unborn baby. Use reliable forms of contraception to prevent pregnancy while using Nolvatam 20 mg Tablet .

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Breast Feeding

Unsafe

Nolvatam 20 mg Tablet is not recommended to use during breastfeeding since it may be unsafe for the breastfed infant. Please seek medical advice if you are a nursing mother before starting Nolvatam 20 mg Tablet .

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Driving

Unsafe

Nolvatam 20 mg Tablet causes tiredness and may affect your ability to drive. Do not drive or operate machinery if you experience any unmanageable side effects with Nolvatam 20 mg Tablet .

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Liver

Consult your doctor

Please let your doctor know if you have any history of liver diseases or hepatic impairment before starting Nolvatam 20 mg Tablet .

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Kidney

Consult your doctor

Please let your doctor know if you have any history of kidney diseases before starting Nolvatam 20 mg Tablet .

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Children

Consult your doctor

Nolvatam 20 mg Tablet is not recommended in children younger than two years of age.

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Heart

Consult your doctor

Nolvatam 20 mg Tablet should be used with caution in patients with heart problems. Inform your doctor about any heart-related conditions before taking Nolvatam 20 mg Tablet .

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Geriatrics

Caution

Nolvatam 20 mg Tablet should be given with caution in elderly patients due to an increased risk of side effects. Seek medical advice before using Nolvatam 20 mg Tablet .

FAQs

Nolvatam 20 mg Tablet is primarily used to treat breast cancer. It is also used to treat infertility caused by a failure in the ovulation (produce and release) process in women.

Nolvatam 20 mg Tablet contains Tamoxifen, an antineoplastic agent. It blocks the effects of the female sex hormone called oestrogen. This process of inhibiting the hormone's action can decrease cancer cells' growth in breast cancer.

Nolvatam 20 mg Tablet should be used with caution and under doctor's supervision only if you have any medical history of liver or kidney diseases, heart diseases, high cholesterol levels, high blood pressure, diabetes, history of stroke or blood clot, receiving chemotherapy, and cataracts. Let your doctor know if you have any other medical concerns before using Nolvatam 20 mg Tablet .

During treatment with Nolvatam 20 mg Tablet , it is essential to look for any signs of a stroke (slurred speech, sudden weakness or numbness, severe headache), signs of a blood clot in the lung (chest pain, sudden coughing, wheezing, rapid breathing, coughing up blood), and signs of a blood clot in one or both legs (pain, swelling, warmth, redness). If you further notice any symptoms that are not manageable or unusual, please seek prompt medical advice.

Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule. Do not double the dose.

Swallow the medicine as a whole with a glass of water. You can take it with or without food at regular intervals, as prescribed by the doctor. Do not crush, chew or break it. The dose of Nolvatam 20 mg Tablet will be suggested by your doctor based on your condition.

Take the missed dose as soon as you remember. If it's almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for the missed one. If you are unsure about what to do, consult your pharmacist for guidance.

Do not stop taking Nolvatam 20 mg Tablet as it may increase the risk or progression of the cancer. It is advised to complete the course prescribed by your doctor. However, if you face any difficulty while taking Nolvatam 20 mg Tablet consult your doctor immediately.

The common side effects of Nolvatam 20 mg Tablet include hot flashes, headache, muscle aches, leg cramps, tiredness, nausea, thinning of hair and numbness or tingling sensation. Not everyone experiences these side effects, and they can vary from person to person. If the side effects persist or worsen, please consult your doctor.

Country of origin

India
Other Info - NOL0040

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