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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Norflox 400 Tablet is used to treat bacterial infections. It contains Norfloxacin and Lactic acid bacillus. Norfloxacin belongs to a class of drugs called quinolone antibiotics. It is bactericidal (kills bacteria) and works by inhibiting bacterial DNA gyrase, an enzyme required for DNA replication, transcription, and repair. Lactic acid bacillus is a probiotic (live bacteria with health benefits) that restores good bacteria in the gut.

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Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Norflox 400 Tablet

Norflox 400 Tablet belongs to the class of 'antibiotics', primarily used to treat bacterial infections. Bacterial infection occurs when harmful bacteria grow in the body and causes illness. It can infect any part of the body and multiply very quickly. Norflox 400 Tablet is not recommended to treat viral infections, such as the common cold and flu.

Norflox 400 Tablet contains Norfloxacin and Lactic acid bacillus. Norfloxacin belongs to a class of drugs called quinolone antibiotics. It is bactericidal (kills bacteria) and works by inhibiting bacterial DNA gyrase, an enzyme required for DNA replication, transcription, and repair. Lactic acid bacillus is a probiotic (live bacteria with health benefits) that restores good bacteria in the gut.

Take Norflox 400 Tablet as advised by a doctor. Norflox 400 Tablet may cause side effects, although not everybody gets them. Common side effects include nausea, heartburn, diarrhoea, dizziness, headache, and trouble sleeping. Most of these side effects do not require medical attention and gradually resolve over time. If these side effects persist longer, please consult your doctor.

Let your doctor know if you have liver/kidney diseases, heart rhythm disorders, tendon problems, fits, diabetes, hypokalaemia/low potassium levels or muscle/nerve disorders. Norflox 400 Tablet should be used only with a doctor's advice during pregnancy and breastfeeding. Avoid consuming alcohol while being treated with this medicine, as it can make you dizzy. Do not drive or operate machinery since it can make you dizzy and interfere with your driving ability. The safety and efficacy of Norflox 400 Tablet have not been established in children; for more information, please seek medical advice.

Uses of Norflox 400 Tablet

Norflox 400 Tablet is used in the treatment of Bacterial infections. The detailed uses of Norflox 400 Tablet are as follows:

  • Urinary Tract Infections (UTIs): Norflox 400 Tablet treats urinary tract infections such as pyelonephritis, cystitis, and urethritis caused by bacteria.
  • Prostatitis: Norflox 400 Tablet treats bacterial prostatitis by reducing inflammation and infection in the prostate gland.
  • Treatment of Gonococcal Infections: Norflox 400 Tablet effectively treats gonococcal infections by eliminating the bacteria and relieving symptoms.
  • Gastrointestinal Infections: Norflox 400 Tablet may be employed in managing certain gastrointestinal infections, particularly those caused by specific types of bacteria, providing relief from symptoms such as diarrhoea and stomach pain.
  • Respiratory Tract Infections: Norflox 400 Tablet treats mild to moderate respiratory tract infections caused by susceptible bacteria, promoting recovery and symptom relief.
  • Anthrax Exposure: Norflox 400 Tablet is used as a preventive treatment for potential anthrax exposure, protecting against the serious bacterial infection caused by Bacillus anthracis.

Directions for Use

  • Norflox 400 Tablet can be taken with or without food as advised by the doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Norflox 400 Tablet as a whole with a glass of water.
  • Do not chew, crush or break it.

Medicinal Benefits

Norflox 400 Tablet contains Norfloxacin and Lactic acid bacillus. Norfloxacin is bactericidal and works by inhibiting bacterial DNA gyrase, an enzyme required for DNA replication, transcription, and repair. Lactic acid bacillus is a probiotic and a lactic acid-producing bacteria. It supports the growth of friendly bacteria in the intestine and maintains a healthy microflora balance in the gut environment.

How Norflox 400 Tablet Works

Norflox 400 Tablet contains Norfloxacin and Lactic acid bacillus. Norfloxacin belongs to a class of drugs called quinolone antibiotics. It is bactericidal (kills bacteria) and works by inhibiting bacterial DNA gyrase, an enzyme required for DNA replication, transcription, and repair. Lactic acid bacillus is a probiotic (live bacteria with health benefits) that restores good bacteria in the gut.

Storage

• Store in a cool and dry place away from sunlight.• Keep out of sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Norflox 400 Tablet
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Always wear loose-fitting clothes which are suitable for your activity.
  • Include the diet containing fruits like watermelon, grapes, bananas and green leafy vegetables.
  • Drink plenty of water stay hydrated.
  • Avoid moving more and staying in hot sun.

What if I have taken an overdose of Norflox 400 Tablet

Do not take more than the prescribed dose. If you accidentally take more than the prescribed dose, please go to the emergency department of the closest hospital or nursing home. No specific side effects have been reported under these circumstances.

Drug Warnings

Do not use Norflox 400 Tablet if you are allergic to antibiotics. Let your doctor know if you have any liver/kidney diseases, heart rhythm disorders, tendon problems, fits, diabetes, hypokalaemia/low potassium levels or muscle/nerve disorders before using this medicine. Pregnant and breastfeeding women should consult their doctor before taking Norflox 400 Tablet . Avoid or limit consuming alcohol while being treated, as it can make you dizzy. Do not drive or operate machinery since it can make you dizzy and interfere with your driving ability. The safety and efficacy of Norflox 400 Tablet have not been established in children; for more information, please seek medical advice.

Drug-Drug Interactions

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NorfloxacinBepridil
Critical

Drug-Drug Interactions

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NorfloxacinBepridil
Critical
How does the drug interact with Norflox 400 Tablet:
Using bepridil together with Norflox 400 Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Norflox 400 Tablet with Bepridil is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, or a fast or pounding heartbeat. Do not stop using any medications without talking to a doctor.
How does the drug interact with Norflox 400 Tablet:
Coadministration of Norflox 400 Tablet with Disopyramide can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Norflox 400 Tablet with Disopyramide together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Norflox 400 Tablet:
Coadministration of Norflox 400 Tablet with Cisapride can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Norflox 400 Tablet with Cisapride together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Norflox 400 Tablet:
Coadministration of Norflox 400 Tablet with Sotalol can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Norflox 400 Tablet with Sotalol together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
NorfloxacinMesoridazine
Critical
How does the drug interact with Norflox 400 Tablet:
Using Mesoridazine together with Norflox 400 Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Mesoridazine with Norflox 400 Tablet is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
How does the drug interact with Norflox 400 Tablet:
The combination of Amiodarone and Norflox 400 Tablet may significantly raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Despite the fact that Amiodarone and Norflox 400 Tablet interact, it can be taken if prescribed by a doctor. If you get dizziness, lightheadedness, fainting, or fast or racing heartbeats, consult a doctor. Do not stop taking any medications without visiting a doctor.
NorfloxacinMetrizamide
Severe
How does the drug interact with Norflox 400 Tablet:
Coadministration of Norflox 400 Tablet with Metrizamide may cause seizures (sudden, violent, uncontrollable contraction of a group of muscles).

How to manage the interaction:
Although there is a possible interaction between Norflox 400 Tablet and Metrizamide, you can take these medicines together if prescribed by your doctor. If you have seizures or a head injury, it's important to contact a doctor right away. Don't hesitate to reach out if you're experiencing any of these symptoms. Do not stop using any medications without talking to a doctor.
How does the drug interact with Norflox 400 Tablet:
Coadministration of Bupropion with Norflox 400 Tablet may enhance the risk or severity seizure (fits).

How to manage the interaction:
Co-administration of bupropion along with Norflox 400 Tablet can lead to an interaction, it can be taken if recommended by a doctor. While taking these medications, you should avoid tasks that need mental attention, such as driving or operating dangerous machinery. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Norflox 400 Tablet:
Co-administration of Norflox 400 Tablet with Methylprednisolone can increase the risk or severity of tendinitis (inflammation of the tendons attached to the muscle and bones).

How to manage the interaction:
Taking Norflox 400 Tablet with Methylprednisolone together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience any symptoms such as Stiff joints or difficulty moving your joints, joint pains, Swelling, or skin discoloration, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Norflox 400 Tablet:
Coadministration of Norflox 400 Tablet with Citalopram can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Norflox 400 Tablet with Citalopram together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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NORFLOXACIN-400MGCaffeine containing foods/drinks, Fruit juices
Moderate

Drug-Food Interactions

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NORFLOXACIN-400MGCaffeine containing foods/drinks, Fruit juices
Moderate
Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu, Orange Juice

How to manage the interaction:
Consuming dairy products, cereal, or orange juice with Norflox 400 Tablet can interfere with its absorption and reduce its levels in the blood and urinary tract. Using caffeine together with Norflox 400 Tablet may increase the effects of caffeine. Norflox 400 Tablet dose should be taken at least one hour before or two hours after consuming dairy products, cereal, or orange juice. Avoid taking caffeine with Norflox 400 Tablet. Contact a doctor if you experience headaches, tremors, restlessness, nervousness, insomnia, and increased blood pressure or heart rate.

Diet & Lifestyle Advise

  • Wash your hands often to maintain cleanliness. Avoid sharing personal items like shaving razors.
  • Include whole-grain foods like multigrain bread and brown rice in your diet. 
  • Taking probiotics with antibiotics reduces the risk of antibiotic-associated diarrhoea. 
  • Try taking yoghurt, cheese, sauerkraut, and kimchi that help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet that is easily digested by your gut bacteria. Fibre foods may also help restore healthy gut bacteria after a course of antibiotics. 
  • Avoid intake of alcoholic beverages as they can make you dehydrated and affect your sleep. 
  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep. 

Habit Forming

No

Therapeutic Class

ANTIBIOTICS
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Alcohol

Caution

It is advised to avoid alcohol consumption while using Norflox 400 Tablet . Alcohol consumption may cause increased dizziness while being treated with Norflox 400 Tablet . Please consult your doctor for more information.

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Pregnancy

Consult your doctor

It is not known whether this medicine can harm your unborn baby. Please consult your doctor before taking Norflox 400 Tablet if you are pregnant or planning pregnancy.

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Breast Feeding

Consult your doctor

There is limited information on how this medicine affects breastfed infants. Please consult your doctor before taking Norflox 400 Tablet if you are breastfeeding.

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Driving

Caution

Norflox 400 Tablet may make you feel dizzy or drowsy. Do not drive if you are not mentally alert or experience any symptoms that affect your ability to drive or operate machinery.

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Liver

Consult your doctor

If you pre-existing or a history of liver disease, inform your doctor before taking Norflox 400 Tablet . Your doctor will weigh the benefits and potential risks before prescribing Norflox 400 Tablet .

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Kidney

Consult your doctor

If you pre-existing or a history of kidney disease, inform your doctor before taking Norflox 400 Tablet . Your doctor will weigh the benefits and potential risks before prescribing Norflox 400 Tablet . Dose adjustment may be required.

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Children

Caution

The safety and efficacy of Norflox 400 Tablet have not been established in children; for more information, please seek medical advice.

Have a query?

FAQs

Norflox 400 Tablet is used to treat bacterial infections.

Norflox 400 Tablet is an antibiotic that treats bacterial infections. It inhibits the bacterial DNA gyrase enzyme required for DNA replication, transcription, and repair.

Norflox 400 Tablet can affect the live vaccines like typhoid and decrease effectiveness. Please ask your doctor if you can take Norflox 400 Tablet in case you are supposed to undergo any vaccinations.

It is recommended to complete the course even if you feel better as it is an antibiotic, and stopping it midway may lead to recurring infections. Hence, please continue taking Norflox 400 Tablet for as long as your doctor has prescribed.

Diarrhoea can be a side effect of Norflox 400 Tablet . Drink enough fluids and eat fibre-rich food if you experience diarrhoea. If you find blood in your stools (tarry stools) or experience excess diarrhoea, consult your doctor. Do not take anti-diarrhoeal medicine on your own.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - NOR0008

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