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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Norflox 400 Tablet is used to treat bacterial infections caused by susceptible bacteria. It is indicated in the treatment of urinary tract infections, prostatitis (prostate inflammation) and gonorrhoea (sexually transmitted disease). Additionally, it is used to treat infections of the stomach and intestine like traveller's diarrhoea. It contains Norfloxacin, which kills the bacteria and treats bacterial infections. In some cases, it may cause common side effects such as abdominal cramps, nausea, headache, and dizziness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

NORFLOXACIN-400MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Norflox 400 Tablet

Norflox 400 Tablet belongs to the group of quinolones antibiotics used to treat bacterial infections caused by susceptible bacteria. It is indicated in the treatment of urinary tract infections, prostatitis (prostate inflammation) and gonorrhoea (sexually transmitted disease). Additionally, Norflox 400 Tablet is used to treat infections of the stomach and intestine like traveller’s diarrhoea. 

Norflox 400 Tablet contains Norfloxacin which inhibits the synthesis of an enzyme called DNA gyrase. Thereby kills the bacteria and treats bacterial infections. Norflox 400 Tablet has a broad spectrum antibacterial activity against gram-positive and gram-negative aerobic bacteria.

Take Norflox 400 Tablet as prescribed. In some cases, Norflox 400 Tablet may cause common side-effects such as abdominal cramps, nausea, headache, and dizziness. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side-effects persist or worsen.

Inform your doctor if you experience pain in tendons, swelling, or inflammation as Norflox 400 Tablet is associated with an increased risk of tendon rupture and tendonitis; this risk is higher in patients older than 60years, in people taking steroids, or who have had kidney, heart or lung transplant. Norflox 400 Tablet may cause dizziness and light-headedness, so drive only if you are alert. Avoid alcohol consumption while taking Norflox 400 Tablet as it may cause increased dizziness.

Uses of Norflox 400 Tablet

Norflox 400 Tablet is used for the treatment of Bacterial infections, Traveller's diarrhoea. The detailed uses of Norflox 400 Tablet are as follows:
• Urinary Tract Infections (UTIs): Norflox 400 Tablet is an antibiotic used to treat urinary tract infections (UTIs) caused by certain bacteria.
• Gastrointestinal Infections: Norflox 400 Tablet can be used to treat certain types of gastrointestinal infections, including diarrhea caused by specific bacteria.
• Prostatitis: Norflox 400 Tablet is also indicated for the treatment of prostatitis, an inflammation of the prostate gland often caused by bacterial infection.
• Gynecological Infections: Norflox 400 Tablet treats certain bacterial gynecological infections, especially those affecting the lower reproductive system.

Directions for Use

Swallow it as a whole with water; do not crush or chew the medication.

Medicinal Benefits

Norflox 400 Tablet belongs to the group of medicines called quinolones antibiotics used to treat bacterial infections of the prostate, urinary tract and gonorrhoea (sexually transmitted disease). Additionally, Norflox 400 Tablet is also used to treat traveller’s diarrhoea. Norflox 400 Tablet is bactericidal in nature. It works by inhibiting the synthesis of bacterial DNA gyrase; this prevents the bacteria from repairing and multiplying. Thereby, kills the bacteria and treats infections. Norflox 400 Tablet is a broad-spectrum antibiotic effective against a wide range of gram-positive and gram-negative bacteria.

How Norflox 400 Tablet Works

Norflox 400 Tablet contains Norfloxacin which inhibits the synthesis of an enzyme called DNA gyrase. Thereby kills the bacteria and treats bacterial infections. Norflox 400 Tablet has a broad spectrum antibacterial activity against gram-positive and gram-negative aerobic bacteria.

Storage

Store in a cool and dry place away from sunlight
Side effects of Norflox 400 Tablet
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Always wear loose-fitting clothes which are suitable for your activity.
  • Include the diet containing fruits like watermelon, grapes, bananas and green leafy vegetables.
  • Drink plenty of water stay hydrated.
  • Avoid moving more and staying in hot sun.

What if I have taken an overdose of Norflox 400 Tablet

Do not take more than the prescribed dose of Norflox 400 Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Norflox 400 Tablet if you are allergic to any of its contents; if you had swelling or tearing of tendons while taking quinolone antibiotics. Norflox 400 Tablet is associated with an increased risk of tendon rupture and tendonitis in all age groups; this risk is higher in patients older than 60 years, people taking corticosteroids, who have had kidney, heart or lung transplants. Consult your doctor immediately if you experience tendon pain, swelling or inflammation while taking Norflox 400 Tablet . Do not take Norflox 400 Tablet if you have myasthenia gravis, as it may cause increased muscle weakness. Talk to your doctor if you have epilepsy, low levels of potassium, nervous or muscle problems, head injury or brain tumour, diabetes,  rheumatoid arthritis, heart, kidney or liver problems. Consult your doctor if you are pregnant or breastfeeding. Avoid alcohol consumption while taking Norflox 400 Tablet as it may cause increased dizziness. Norflox 400 Tablet may cause dizziness and vision problems, so be cautious while driving.

Drug-Drug Interactions

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NorfloxacinDisopyramide
Critical
NorfloxacinMesoridazine
Critical

Drug-Drug Interactions

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NorfloxacinDisopyramide
Critical
How does the drug interact with Norflox 400 Tablet:
Coadministration of Norflox 400 Tablet with Disopyramide can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Norflox 400 Tablet with Disopyramide together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
NorfloxacinMesoridazine
Critical
How does the drug interact with Norflox 400 Tablet:
Using Mesoridazine together with Norflox 400 Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Mesoridazine with Norflox 400 Tablet is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
NorfloxacinAmiodarone
Critical
How does the drug interact with Norflox 400 Tablet:
The combination of Amiodarone and Norflox 400 Tablet may significantly raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Despite the fact that Amiodarone and Norflox 400 Tablet interact, it can be taken if prescribed by a doctor. If you get dizziness, lightheadedness, fainting, or fast or racing heartbeats, consult a doctor. Do not stop taking any medications without visiting a doctor.
NorfloxacinSotalol
Critical
How does the drug interact with Norflox 400 Tablet:
Coadministration of Norflox 400 Tablet with Sotalol can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Norflox 400 Tablet with Sotalol together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
NorfloxacinBepridil
Critical
How does the drug interact with Norflox 400 Tablet:
Using bepridil together with Norflox 400 Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Norflox 400 Tablet with Bepridil is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, or a fast or pounding heartbeat. Do not stop using any medications without talking to a doctor.
NorfloxacinCisapride
Critical
How does the drug interact with Norflox 400 Tablet:
Coadministration of Norflox 400 Tablet with Cisapride can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Norflox 400 Tablet with Cisapride together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
NorfloxacinCeritinib
Severe
How does the drug interact with Norflox 400 Tablet:
Coadministration of Norflox 400 Tablet with ceritinib can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Norflox 400 Tablet with Ceritinib together can result in an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
NorfloxacinInsulin aspart
Severe
How does the drug interact with Norflox 400 Tablet:
Taking insulin aspart with Norflox 400 Tablet affects blood glucose levels. Both hyperglycemia (high blood glucose) and, less frequently, hypoglycemia have been reported.

How to manage the interaction:
There could be a possible interaction between insulin aspart and Norflox 400 Tablet but can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms such as headache, dizziness, drowsiness, nervousness, confusion, tremors, nausea, hunger, weakness, sweating, palpitation, rapid heartbeat, increased thirst, increased hunger, and increased urination. Do not stop using any medications without talking to a doctor.
NorfloxacinTramadol
Severe
How does the drug interact with Norflox 400 Tablet:
Coadministration of Norflox 400 Tablet with Tramadol may cause seizures (sudden, violent, uncontrollable contraction of a group of muscles).

How to manage the interaction:
Taking Norflox 400 Tablet with tramadol together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms such as confusion, hallucination, seizure, increased heart rate, blurred vision, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NorfloxacinCabozantinib
Severe
How does the drug interact with Norflox 400 Tablet:
Coadministration of Norflox 400 Tablet with Cabozantinib can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Norflox 400 Tablet with Cabozantinib together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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NORFLOXACIN-400MGCaffeine containing foods/drinks, Fruit juices
Moderate

Drug-Food Interactions

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NORFLOXACIN-400MGCaffeine containing foods/drinks, Fruit juices
Moderate
Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu, Orange Juice

How to manage the interaction:
Consuming dairy products, cereal, or orange juice with Norflox 400 Tablet can interfere with its absorption and reduce its levels in the blood and urinary tract. Using caffeine together with Norflox 400 Tablet may increase the effects of caffeine. Norflox 400 Tablet dose should be taken at least one hour before or two hours after consuming dairy products, cereal, or orange juice. Avoid taking caffeine with Norflox 400 Tablet. Contact a doctor if you experience headaches, tremors, restlessness, nervousness, insomnia, and increased blood pressure or heart rate.

Diet & Lifestyle Advise

  • Antibiotics can alter the useful bacteria in the stomach, which help in digestion. Therefore, you are advised to take foods rich in probiotics, such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.

  • Eat fibre-rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.

  • Avoid foods rich in calcium, grapefruit and grapefruit juice, as they might hinder the absorption of antibiotics.

  • Avoid consumption of alcohol and usage of tobacco.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Norflox 400 Tablet Substitute

Substitutes safety advice
  • Norflokem 400Mg Tablet

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    3.06per tablet
  • Anquin 400mg Tablet

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  • Alflox-400 Tablet 10's

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    7.70per tablet
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Alcohol

Unsafe

Avoid consuming alcohol while taking Norflox 400 Tablet as it may cause increased dizziness.

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Pregnancy

Caution

Norflox 400 Tablet belongs to pregnancy category C. Please consult your doctor if you are pregnant, your doctor will prescribe Norflox 400 Tablet only if the benefits outweigh the risks.

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Breast Feeding

Caution

It is unknown if Norflox 400 Tablet passes into breastmilk. Consult your doctor if you are breastfeeding.

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Driving

Caution

Norflox 400 Tablet may cause dizziness and light-headedness. So, drive only if you are alert.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor if you have liver impairment/liver disease.

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Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease.

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Children

Unsafe

Norflox 400 Tablet is not recommended for children below 18 years as safety and effectiveness have not been established.

Have a query?

FAQs

Norflox 400 Tablet is used to treat bacterial infections caused by susceptible bacteria. It is indicated in the treatment of urinary tract infections, prostatitis (prostate inflammation) and gonorrhoea (sexually transmitted disease). Additionally, Norflox 400 Tablet is used to treat infections of the stomach and intestine like traveller’s diarrhoea.

Norflox 400 Tablet works by inhibiting the synthesis of bacterial DNA gyrase; this prevents the bacteria from repairing and multiplying. Thereby, helps in treating the infections.

Norflox 400 Tablet may cause photosensitivity (sensitivity to sunlight) and can make you sunburn easily. Avoid prolonged exposure to sunlight or tanning beds. Always wear protective clothing and sunscreen with SPF 30 or higher before going out.

It is recommended to complete the course of Norflox 400 Tablet even if you feel better as it is an antibiotic, and leaving it in between may lead to even severe infection. To treat your condition effectually, continue taking Norflox 400 Tablet for as long as your doctor has prescribed it.

Avoid consuming dairy products such as milk and yoghurt along with Norflox 400 Tablet as they may decrease the effectiveness of Norflox 400 Tablet .

Do not take Norflox 400 Tablet on your own, as self-medication may lead to antibiotic-resistance in which antibiotics fail to act against specific bacterial infections.

Maintain a minimum gap of two hours between Norflox 400 Tablet and antacid, anti-ulcer (sucralfate), anti-HIV (didanosine), vitamin and mineral medicines. However, consult your doctor before taking other medicines with Norflox 400 Tablet .

Consult your doctor before taking Norflox 400 Tablet if you have diabetes, as Norflox 400 Tablet may cause hypoglycaemia (low blood sugar levels). Regularly monitor blood sugar levels while taking Norflox 400 Tablet to avoid hypoglycaemic events.

Norflox 400 Tablet may cause changes in liver function tests and prothrombin time (time taken for blood clotting). Inform the person doing the tests that you are taking Norflox 400 Tablet .

If you're feeling better, don't stop taking the medicine! Instead, report your progress to your doctor and follow their advice. Remember, finishing the entire course of therapy is crucial to ensuring the infection is fully gone and doesn't come back. Your doctor will guide you on what to do next, so check in with them.

Common side-effects of Norflox 400 Tablet may include abdominal cramps, nausea, headache, and dizziness. Most of these side-effects do not require medical attention and will resolve gradually. However, you are advised to talk to your doctor if the side-effects persist or worsen.

I am a pregnant woman. Is it safe to use Norflox 400 Tablet ?

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - NOR0008

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