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  3. NORFLOXACIN 400MG TABLET

NORFLOXACIN 400MG TABLET, Pack of 10 TABLETS
NORFLOXACIN 400MG TABLET, Pack of 10 TABLETS

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Composition :

NORFLOXACIN-400MG

Manufacturer/Marketer :

Cadila Healthcare Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About NORFLOXACIN 400MG TABLET

NORFLOXACIN 400MG TABLET belongs to the group of quinolones antibiotics used to treat bacterial infections caused by susceptible bacteria. It is indicated in the treatment of urinary tract infections, prostatitis (prostate inflammation) and gonorrhoea (sexually transmitted disease). Additionally, NORFLOXACIN 400MG TABLET is used to treat infections of the stomach and intestine like traveller’s diarrhoea. 

NORFLOXACIN 400MG TABLET contains Norfloxacin which inhibits the synthesis of an enzyme called DNA gyrase. Thereby kills the bacteria and treats bacterial infections. NORFLOXACIN 400MG TABLET has a broad spectrum antibacterial activity against gram-positive and gram-negative aerobic bacteria.

Take NORFLOXACIN 400MG TABLET as prescribed. In some cases, NORFLOXACIN 400MG TABLET may cause common side-effects such as abdominal cramps, nausea, headache, and dizziness. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side-effects persist or worsen.

Inform your doctor if you experience pain in tendons, swelling, or inflammation as NORFLOXACIN 400MG TABLET is associated with an increased risk of tendon rupture and tendonitis; this risk is higher in patients older than 60years, in people taking steroids, or who have had kidney, heart or lung transplant. NORFLOXACIN 400MG TABLET may cause dizziness and light-headedness, so drive only if you are alert. Avoid alcohol consumption while taking NORFLOXACIN 400MG TABLET as it may cause increased dizziness.

Uses of NORFLOXACIN 400MG TABLET

NORFLOXACIN 400MG TABLET is used for the treatment of Bacterial infections, Traveller's diarrhoea. The detailed uses of NORFLOXACIN 400MG TABLET are as follows:
• Urinary Tract Infections (UTIs): NORFLOXACIN 400MG TABLET is an antibiotic used to treat urinary tract infections (UTIs) caused by certain bacteria.
• Gastrointestinal Infections: NORFLOXACIN 400MG TABLET can be used to treat certain types of gastrointestinal infections, including diarrhea caused by specific bacteria.
• Prostatitis: NORFLOXACIN 400MG TABLET is also indicated for the treatment of prostatitis, an inflammation of the prostate gland often caused by bacterial infection.
• Gynecological Infections: NORFLOXACIN 400MG TABLET treats certain bacterial gynecological infections, especially those affecting the lower reproductive system.

Directions for Use

Swallow it as a whole with water; do not crush or chew the medication.

Key Benefits

NORFLOXACIN 400MG TABLET belongs to the group of medicines called quinolones antibiotics used to treat bacterial infections of the prostate, urinary tract and gonorrhoea (sexually transmitted disease). Additionally, NORFLOXACIN 400MG TABLET is also used to treat traveller’s diarrhoea. NORFLOXACIN 400MG TABLET is bactericidal in nature. It works by inhibiting the synthesis of bacterial DNA gyrase; this prevents the bacteria from repairing and multiplying. Thereby, kills the bacteria and treats infections. NORFLOXACIN 400MG TABLET is a broad-spectrum antibiotic effective against a wide range of gram-positive and gram-negative bacteria.

How NORFLOXACIN 400MG TABLET Works

NORFLOXACIN 400MG TABLET contains Norfloxacin which inhibits the synthesis of an enzyme called DNA gyrase. Thereby kills the bacteria and treats bacterial infections. NORFLOXACIN 400MG TABLET has a broad spectrum antibacterial activity against gram-positive and gram-negative aerobic bacteria.

Storage

Store in a cool and dry place away from sunlight
Side effects of Norfloxacin 400mg Tablet
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Always wear loose-fitting clothes which are suitable for your activity.
  • Include the diet containing fruits like watermelon, grapes, bananas and green leafy vegetables.
  • Drink plenty of water stay hydrated.
  • Avoid moving more and staying in hot sun.

What if I have taken an overdose of NORFLOXACIN 400MG TABLET

Do not take more than the prescribed dose of NORFLOXACIN 400MG TABLET as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take NORFLOXACIN 400MG TABLET if you are allergic to any of its contents; if you had swelling or tearing of tendons while taking quinolone antibiotics. NORFLOXACIN 400MG TABLET is associated with an increased risk of tendon rupture and tendonitis in all age groups; this risk is higher in patients older than 60 years, people taking corticosteroids, who have had kidney, heart or lung transplants. Consult your doctor immediately if you experience tendon pain, swelling or inflammation while taking NORFLOXACIN 400MG TABLET. Do not take NORFLOXACIN 400MG TABLET if you have myasthenia gravis, as it may cause increased muscle weakness. Talk to your doctor if you have epilepsy, low levels of potassium, nervous or muscle problems, head injury or brain tumour, diabetes,  rheumatoid arthritis, heart, kidney or liver problems. Consult your doctor if you are pregnant or breastfeeding. Avoid alcohol consumption while taking NORFLOXACIN 400MG TABLET as it may cause increased dizziness. NORFLOXACIN 400MG TABLET may cause dizziness and vision problems, so be cautious while driving.

Drug-Drug Interactions

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NorfloxacinSotalol
Critical
NorfloxacinCisapride
Critical

Drug-Drug Interactions

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NorfloxacinSotalol
Critical
How does the drug interact with Norfloxacin 400mg Tablet 400mg Tablet:
Coadministration of Norfloxacin 400mg Tablet with Sotalol can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Norfloxacin 400mg Tablet with Sotalol together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
NorfloxacinCisapride
Critical
How does the drug interact with Norfloxacin 400mg Tablet 400mg Tablet:
Coadministration of Norfloxacin 400mg Tablet with Cisapride can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Norfloxacin 400mg Tablet with Cisapride together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
NorfloxacinAmiodarone
Critical
How does the drug interact with Norfloxacin 400mg Tablet 400mg Tablet:
The combination of Amiodarone and Norfloxacin 400mg Tablet may significantly raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Despite the fact that Amiodarone and Norfloxacin 400mg Tablet interact, it can be taken if prescribed by a doctor. If you get dizziness, lightheadedness, fainting, or fast or racing heartbeats, consult a doctor. Do not stop taking any medications without visiting a doctor.
NorfloxacinBepridil
Critical
How does the drug interact with Norfloxacin 400mg Tablet 400mg Tablet:
Using bepridil together with Norfloxacin 400mg Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Norfloxacin 400mg Tablet with Bepridil is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, or a fast or pounding heartbeat. Do not stop using any medications without talking to a doctor.
NorfloxacinDisopyramide
Critical
How does the drug interact with Norfloxacin 400mg Tablet 400mg Tablet:
Coadministration of Norfloxacin 400mg Tablet with Disopyramide can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Norfloxacin 400mg Tablet with Disopyramide together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
NorfloxacinMesoridazine
Critical
How does the drug interact with Norfloxacin 400mg Tablet 400mg Tablet:
Using Mesoridazine together with Norfloxacin 400mg Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Mesoridazine with Norfloxacin 400mg Tablet is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
NorfloxacinCeritinib
Severe
How does the drug interact with Norfloxacin 400mg Tablet 400mg Tablet:
Coadministration of Norfloxacin 400mg Tablet with ceritinib can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Norfloxacin 400mg Tablet with Ceritinib together can result in an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
NorfloxacinDeflazacort
Severe
How does the drug interact with Norfloxacin 400mg Tablet 400mg Tablet:
Norfloxacin 400mg Tablet can cause tendinitis (inflammation of the thick fibrous cords that attach muscle to bone) and tendon rupture (injury to the soft tissue that connect muscle to bone), and the risk may be increased when combined with other drugs such as deflazacort.

How to manage the interaction:
Although there is an interaction, Norfloxacin 400mg Tablet can be taken with deflazacort if prescribed by the doctor. However, if you experience pain, or swelling at the back of the ankle, biceps, shoulder, hand, or thumb, consult a doctor immediately. Avoid exercise or use of the affected area until further instruction from your doctor. Do not stop using any medications without talking to a doctor.
NorfloxacinHydroxychloroquine
Severe
How does the drug interact with Norfloxacin 400mg Tablet 400mg Tablet:
Coadministration of Norfloxacin 400mg Tablet with Hydroxychloroquine can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Norfloxacin 400mg Tablet with Hydroxychloroquine together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NorfloxacinInsulin detemir
Severe
How does the drug interact with Norfloxacin 400mg Tablet 400mg Tablet:
Co-administration of Norfloxacin 400mg Tablet and Insulin detemir can have an impact on blood sugar levels. There have been reports of both hyperglycemia (high blood sugar) and, less frequently, hypoglycemia (low blood sugar).

How to manage the interaction:
Although taking Norfloxacin 400mg Tablet and Insulin detemir together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor, if you experience headaches, dizziness, sleepiness, anxiety, disorientation, tremors, nausea, hunger, weakness, sweat, palpitations, and rapid heartbeat, increased-hunger, thirst, and urine. It is recommended to maintain blood glucose levels. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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NORFLOXACIN-400MGCaffeine containing foods/drinks, Fruit juices
Moderate

Drug-Food Interactions

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NORFLOXACIN-400MGCaffeine containing foods/drinks, Fruit juices
Moderate
Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu, Orange Juice

How to manage the interaction:
Consuming dairy products, cereal, or orange juice with Norfloxacin 400mg Tablet can interfere with its absorption and reduce its levels in the blood and urinary tract. Using caffeine together with Norfloxacin 400mg Tablet may increase the effects of caffeine. Norfloxacin 400mg Tablet dose should be taken at least one hour before or two hours after consuming dairy products, cereal, or orange juice. Avoid taking caffeine with Norfloxacin 400mg Tablet. Contact a doctor if you experience headaches, tremors, restlessness, nervousness, insomnia, and increased blood pressure or heart rate.

Diet & Lifestyle Advise

  • Antibiotics can alter the useful bacteria in the stomach, which help in digestion. Therefore, you are advised to take foods rich in probiotics, such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.

  • Eat fibre-rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.

  • Avoid foods rich in calcium, grapefruit and grapefruit juice, as they might hinder the absorption of antibiotics.

  • Avoid consumption of alcohol and usage of tobacco.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

NORFLOXACIN 400MG TABLET Substitute

Substitutes safety advice

  • Norflox 400 Tablet 10's

    by Others

    ₹8.46per tablet

  • Norflokem 400Mg Tablet

    by AYUR

    ₹4.63per tablet

  • Norcin 400 mg Tablet 10's

    by Others

    ₹4.23per tablet

  • Actiflox 400mg Tablet

    by Others

    ₹2.79per tablet

  • Emnorcin 400mg Tablet

    by Others

    ₹1.72per tablet

Product Substitutes

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Alcohol

Unsafe

Avoid consuming alcohol while taking NORFLOXACIN 400MG TABLET as it may cause increased dizziness.

bannner image

Pregnancy

Caution

NORFLOXACIN 400MG TABLET belongs to pregnancy category C. Please consult your doctor if you are pregnant, your doctor will prescribe NORFLOXACIN 400MG TABLET only if the benefits outweigh the risks.

bannner image

Breast Feeding

Caution

It is unknown if NORFLOXACIN 400MG TABLET passes into breastmilk. Consult your doctor if you are breastfeeding.

bannner image

Driving

Caution

NORFLOXACIN 400MG TABLET may cause dizziness and light-headedness. So, drive only if you are alert.

bannner image

Liver

Caution

Dose adjustment may be needed. Please consult your doctor if you have liver impairment/liver disease.

bannner image

Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease.

bannner image

Children

Unsafe

NORFLOXACIN 400MG TABLET is not recommended for children below 18 years as safety and effectiveness have not been established.

Have a query?

FAQs

NORFLOXACIN 400MG TABLET is used to treat bacterial infections caused by susceptible bacteria. It is indicated in the treatment of urinary tract infections, prostatitis (prostate inflammation) and gonorrhoea (sexually transmitted disease). Additionally, NORFLOXACIN 400MG TABLET is used to treat infections of the stomach and intestine like traveller’s diarrhoea.

NORFLOXACIN 400MG TABLET works by inhibiting the synthesis of bacterial DNA gyrase; this prevents the bacteria from repairing and multiplying. Thereby, helps in treating the infections.

NORFLOXACIN 400MG TABLET may cause photosensitivity (sensitivity to sunlight) and can make you sunburn easily. Avoid prolonged exposure to sunlight or tanning beds. Always wear protective clothing and sunscreen with SPF 30 or higher before going out.

It is recommended to complete the course of NORFLOXACIN 400MG TABLET even if you feel better as it is an antibiotic, and leaving it in between may lead to even severe infection. To treat your condition effectually, continue taking NORFLOXACIN 400MG TABLET for as long as your doctor has prescribed it.

Avoid consuming dairy products such as milk and yoghurt along with NORFLOXACIN 400MG TABLET as they may decrease the effectiveness of NORFLOXACIN 400MG TABLET.

Do not take NORFLOXACIN 400MG TABLET on your own, as self-medication may lead to antibiotic-resistance in which antibiotics fail to act against specific bacterial infections.

Maintain a minimum gap of two hours between NORFLOXACIN 400MG TABLET and antacid, anti-ulcer (sucralfate), anti-HIV (didanosine), vitamin and mineral medicines. However, consult your doctor before taking other medicines with NORFLOXACIN 400MG TABLET.

Consult your doctor before taking NORFLOXACIN 400MG TABLET if you have diabetes, as NORFLOXACIN 400MG TABLET may cause hypoglycaemia (low blood sugar levels). Regularly monitor blood sugar levels while taking NORFLOXACIN 400MG TABLET to avoid hypoglycaemic events.

NORFLOXACIN 400MG TABLET may cause changes in liver function tests and prothrombin time (time taken for blood clotting). Inform the person doing the tests that you are taking NORFLOXACIN 400MG TABLET.

If you're feeling better, don't stop taking the medicine! Instead, report your progress to your doctor and follow their advice. Remember, finishing the entire course of therapy is crucial to ensuring the infection is fully gone and doesn't come back. Your doctor will guide you on what to do next, so check in with them.

Common side-effects of NORFLOXACIN 400MG TABLET may include abdominal cramps, nausea, headache, and dizziness. Most of these side-effects do not require medical attention and will resolve gradually. However, you are advised to talk to your doctor if the side-effects persist or worsen.

I am a pregnant woman. Is it safe to use NORFLOXACIN 400MG TABLET?

Country of origin

India

Manufacturer/Marketer address

Sarkhej-Dholka Road, Bhat, Ahmedabad-382 210, INDIA.
Other Info - NOR0054

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

May 13, 2025 | 11:23 AM IST

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Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/019384s066lbl.pdf
  2. https://www.drugs.com/mtm/norfloxacin.html
  3. https://www.medsafe.govt.nz/consumers/cmi/a/arrow-norfloxacin.pdf
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