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  3. Noroxin 400mg Tablet

Noroxin 400mg Tablet, Pack of 1 Tablet
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Noroxin 400mg Tablet is used to treat bacterial infections caused by susceptible bacteria. It is indicated in the treatment of urinary tract infections, prostatitis (prostate inflammation), and gonorrhoea (a sexually transmitted disease). Additionally, it is used to treat infections of the stomach and intestine, such as traveller's diarrhoea. It contains Norfloxacin, which kills the bacteria and treats bacterial infections. In some cases, it may cause common side effects such as abdominal cramps, nausea, diarrhoea, heartburn, headache, and dizziness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and any pre-existing medical conditions.

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Composition :

NORFLOXACIN-400MG

Consume Type :

ORAL

Return Policy :

Not Returnable

About Noroxin 400mg Tablet

Noroxin 400mg Tablet is used to treat bacterial infections such as urinary tract infections, prostatitis (prostate inflammation), and gonorrhoea (a sexually transmitted disease). Additionally, Noroxin 400mg Tablet is used to treat infections of the stomach and intestine, such as traveler’s diarrhoea.

Noroxin 400mg Tablet contains norfloxacin, which works by inhibiting the bacterial enzyme DNA gyrase, thereby preventing bacterial DNA replication and leading to the death of the bacteria.

Take Noroxin 400mg Tablet as prescribed. In some cases, Noroxin 400mg Tablet may cause common side effects such as abdominal cramps, nausea, diarrhoea, heartburn, headache, and dizziness. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.

Take Noroxin 400mg Tablet as prescribed. It can be taken 1 hour before food or 2 hours after food. Swallow the medicine as a whole with a glass of water. The dose and duration of medicine will be decided by the physician.

Before taking Noroxin 400mg Tablet, inform your doctor if you are allergic to any of its ingredients or other fluoroquinolone antibiotics. Also, let your doctor know if you experience pain in tendons, swelling, or inflammation, as Noroxin 400mg Tablet is associated with an increased risk of tendon rupture and tendonitis in those who have had a kidney, heart, or lung transplant.

Uses of Noroxin 400mg Tablet

Noroxin 400mg Tablet is used for the treatment of bacterial infections. The detailed uses of Noroxin 400mg Tablet are as follows:

  • Urinary Tract Infections (UTIs): Noroxin 400mg Tablet is an antibiotic used to treat complicated and uncomplicated urinary tract infections (UTIs) caused by certain bacteria.
  • Gastrointestinal Infections: Noroxin 400mg Tablet can be used to treat infections of the stomach and intestine, such as traveller's diarrhoea.
  • Prostatitis: Noroxin 400mg Tablet is also indicated for the treatment of prostatitis, an inflammation of the prostate gland often caused by bacterial infection.
  • Gynecological Infections: Noroxin 400mg Tablet treats certain bacterial gynecological infections, especially those affecting the lower reproductive system, such as cervical and urethral gonorrhea caused by the bacteria Neisseria gonorrhoeae.

Directions for Use

  • Noroxin 400mg Tablet should be taken at least 1 hour before or 2 hours after a meal.
  • It is usually taken twice daily or as prescribed by your doctor.
  • Swallow Noroxin 400mg Tablet as a whole with a glass of water.
  • Do not crush, chew, break, or open it.

Medicinal Benefits

  • Noroxin 400mg Tablet belongs to the group of medicines called quinolone antibiotics, used to treat bacterial infections.
  • Additionally, Noroxin 400mg Tablet is also used to treat traveller’s diarrhoea.
  • Noroxin 400mg Tablet is bactericidal in nature. It works by inhibiting the synthesis of bacterial DNA gyrase, thereby preventing the bacteria from repairing and multiplying, and ultimately killing them and treating infections.
  • Noroxin 400mg Tablet is a broad-spectrum antibiotic effective against a wide range of gram-positive and gram-negative bacteria.

How Noroxin 400mg Tablet Works

Noroxin 400mg Tablet contains Norfloxacin, which inhibits the synthesis of an enzyme called DNA gyrase, thereby killing the bacteria and treating bacterial infections. Noroxin 400mg Tablet has broad-spectrum antibacterial activity against both Gram-positive and Gram-negative bacteria.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Noroxin 400mg Tablet
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Always wear loose-fitting clothes which are suitable for your activity.
  • Include the diet containing fruits like watermelon, grapes, bananas and green leafy vegetables.
  • Drink plenty of water stay hydrated.
  • Avoid moving more and staying in hot sun.

What if I have taken an overdose of Noroxin 400mg Tablet

Do not take more than the prescribed dose of Noroxin 400mg Tablet, as it may cause serious side effects. If you suspect you have taken an overdose, please consult a doctor immediately.

Drug Warnings

  • Do not take Noroxin 400mg Tablet if you are allergic to any of its ingredients
  • Also, inform your doctor if you have experienced swelling or tendon tearing while taking quinolone antibiotics.
  • Noroxin 400mg Tablet is associated with an increased risk of tendonitis and tendon rupture in all age groups; this risk is higher in patients over 60 years old, those taking corticosteroids, or those who have had kidney, heart, or lung transplants.
  • Consult your doctor immediately if you experience tendon pain, swelling, or inflammation while taking Noroxin 400mg Tablet.
  • Do not take Noroxin 400mg Tablet if you have myasthenia gravis, as it may cause increased muscle weakness.
  • Talk to your doctor if you have epilepsy, low potassium levels, nervous or muscle disorders, head injury or brain tumour, diabetes, rheumatoid arthritis, or heart, kidney, or liver problems.
  • Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding before taking Noroxin 400mg Tablet.
  • Avoid alcohol consumption while taking Noroxin 400mg Tablet, as it may increase dizziness.
  • Noroxin 400mg Tablet may cause dizziness and vision problems, so avoid driving or operating machinery until you are fully alert.

Drug-Drug Interactions

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NorfloxacinBepridil
Critical
NorfloxacinDisopyramide
Critical

Drug-Drug Interactions

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NorfloxacinBepridil
Critical
How does the drug interact with Noroxin 400mg Tablet:
Using bepridil together with Noroxin 400mg Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Noroxin 400mg Tablet with Bepridil is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, or a fast or pounding heartbeat. Do not stop using any medications without talking to a doctor.
NorfloxacinDisopyramide
Critical
How does the drug interact with Noroxin 400mg Tablet:
Coadministration of Noroxin 400mg Tablet with Disopyramide can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Noroxin 400mg Tablet with Disopyramide together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
NorfloxacinAmiodarone
Critical
How does the drug interact with Noroxin 400mg Tablet:
The combination of Amiodarone and Noroxin 400mg Tablet may significantly raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Despite the fact that Amiodarone and Noroxin 400mg Tablet interact, it can be taken if prescribed by a doctor. If you get dizziness, lightheadedness, fainting, or fast or racing heartbeats, consult a doctor. Do not stop taking any medications without visiting a doctor.
NorfloxacinSotalol
Critical
How does the drug interact with Noroxin 400mg Tablet:
Coadministration of Noroxin 400mg Tablet with Sotalol can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Noroxin 400mg Tablet with Sotalol together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
NorfloxacinMesoridazine
Critical
How does the drug interact with Noroxin 400mg Tablet:
Using Mesoridazine together with Noroxin 400mg Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Mesoridazine with Noroxin 400mg Tablet is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
NorfloxacinCisapride
Critical
How does the drug interact with Noroxin 400mg Tablet:
Coadministration of Noroxin 400mg Tablet with Cisapride can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Noroxin 400mg Tablet with Cisapride together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
NorfloxacinIloperidone
Severe
How does the drug interact with Noroxin 400mg Tablet:
Coadministration of Noroxin 400mg Tablet with Iloperidone can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Noroxin 400mg Tablet with Iloperidone together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
NorfloxacinMetrizamide
Severe
How does the drug interact with Noroxin 400mg Tablet:
Coadministration of Noroxin 400mg Tablet with Metrizamide may cause seizures (sudden, violent, uncontrollable contraction of a group of muscles).

How to manage the interaction:
Although there is a possible interaction between Noroxin 400mg Tablet and Metrizamide, you can take these medicines together if prescribed by your doctor. If you have seizures or a head injury, it's important to contact a doctor right away. Don't hesitate to reach out if you're experiencing any of these symptoms. Do not stop using any medications without talking to a doctor.
NorfloxacinBetamethasone
Severe
How does the drug interact with Noroxin 400mg Tablet:
Co-administration of Noroxin 400mg Tablet may cause tendinitis (inflammation of the muscle to bone) and tendon rupture (injuries to the soft tissues that connect muscles and joints), and the risk may be increased when combined with Betamethasone.

How to manage the interaction:
Taking Noroxin 400mg Tablet with Betamethasone together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience Stiff joints or difficulty moving your joints, joint pains, Swelling, or skin discoloration, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NorfloxacinTolazamide
Severe
How does the drug interact with Noroxin 400mg Tablet:
Using Tolazamide and Noroxin 400mg Tablet together can make Tolazamide more effective in treating certain conditions.

How to manage the interaction:
Co-administration of Noroxin 400mg Tablet with Tolazamide can result in an interaction, but it can be taken if your doctor has advised it. If you experience symptoms like high or low blood sugar, severe infections, or other concerning symptoms, it's important to contact a doctor right away. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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NORFLOXACIN-400MGCaffeine containing foods/drinks, Fruit juices
Moderate

Drug-Food Interactions

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NORFLOXACIN-400MGCaffeine containing foods/drinks, Fruit juices
Moderate
Common Foods to Avoid:
Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu, Orange Juice

How to manage the interaction:
Consuming dairy products, cereal, or orange juice with Noroxin 400mg Tablet can interfere with its absorption and reduce its levels in the blood and urinary tract. Using caffeine together with Noroxin 400mg Tablet may increase the effects of caffeine. Noroxin 400mg Tablet dose should be taken at least one hour before or two hours after consuming dairy products, cereal, or orange juice. Avoid taking caffeine with Noroxin 400mg Tablet. Contact a doctor if you experience headaches, tremors, restlessness, nervousness, insomnia, and increased blood pressure or heart rate.

Diet & Lifestyle Advise

  • Antibiotics can alter the beneficial bacteria in the stomach, which help in digestion. Therefore, you are advised to take foods rich in probiotics, such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.
  • Eat fiber-rich food like whole grains, beans, lentils, berries, broccoli, peas, and bananas.
  • Avoid foods rich in calcium, such as dairy products and grapefruit and grapefruit juice, as they may hinder the absorption of antibiotics.
  • Avoid consumption of alcohol and usage of tobacco.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Noroxin 400mg Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid consuming alcohol while taking Noroxin 400mg Tablet, as it may cause increased dizziness.

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Pregnancy

Caution

Noroxin 400mg Tablet belongs to pregnancy category C. Please consult your doctor if you are pregnant or planning to become pregnant. Your doctor will prescribe Noroxin 400mg Tablet only if the benefits outweigh the risks.

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Breast Feeding

Caution

It is unknown if Noroxin 400mg Tablet passes into breastmilk. Consult your doctor if you are breastfeeding before taking Noroxin 400mg Tablet.

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Driving

Unsafe

Noroxin 400mg Tablet may cause dizziness and light-headedness. So, drive only if you are alert.

bannner image

Liver

Caution

Dose adjustment may be needed. Please consult your doctor if you have liver impairment/liver disease.

bannner image

Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have kidney impairment/kidney disease.

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Children

Unsafe

Noroxin 400mg Tablet is not recommended for children below 18 years, as its safety and effectiveness have not been established in this age group.

Have a query?

FAQs

Noroxin 400mg Tablet is used to treat bacterial infections caused by susceptible bacteria. It is indicated in the treatment of urinary tract infections‚ prostatitis (prostate inflammation), and gonorrhoea (a sexually transmitted disease). Additionally, Noroxin 400mg Tablet is used to treat infections of the stomach and intestine, such as traveller's diarrhoea.

Noroxin 400mg Tablet contains Norfloxacin, which works by inhibiting the synthesis of an enzyme called DNA gyrase. Thereby, it kills the bacteria and treats bacterial infections.

Noroxin 400mg Tablet may cause photosensitivity (sensitivity to sunlight) and increase your risk of sunburn. Avoid prolonged exposure to sunlight or tanning beds. Always wear protective clothing and sunscreen with an SPF of 30 or higher before going outdoors.

It is recommended to complete the course of Noroxin 400mg Tablet, even if you feel better, as it is an antibiotic, and leaving it incomplete may lead to a more severe infection. To treat your condition effectually, continue taking Noroxin 400mg Tablet for as long as your doctor has prescribed it.

Avoid consuming dairy products, such as milk and yoghurt, along with Noroxin 400mg Tablet, as they may decrease the effectiveness of Noroxin 400mg Tablet.

Do not take Noroxin 400mg Tablet on your own, as self-medication may lead to antibiotic resistance, in which antibiotics fail to act against specific bacterial infections.

Maintain a minimum gap of two hours between Noroxin 400mg Tablet and antacids, anti-ulcer medications (such as sucralfate), anti-HIV medications (like didanosine), and vitamin and mineral supplements. However, consult your doctor before taking other medicines with Noroxin 400mg Tablet.

Consult your doctor before taking Noroxin 400mg Tablet if you have diabetes, as Noroxin 400mg Tablet may cause hypoglycaemia (low blood sugar levels). Regularly monitor blood sugar levels while taking Noroxin 400mg Tablet to avoid hypoglycaemic events.

Noroxin 400mg Tablet may cause changes in liver function tests and prothrombin time (time taken for blood clotting). Inform the person doing the tests that you are taking Noroxin 400mg Tablet.

If you start feeling better, do not stop taking the medicine on your own. Instead, please inform your doctor about your progress and follow their advice. Completing the entire course of therapy is crucial to ensure the infection is fully treated and does not return. Your doctor will guide you on the next steps, so be sure to check in with them.

Common side effects of Noroxin 400mg Tablet may include abdominal cramps, nausea, headache, and dizziness. Most of these side effects do not require medical attention and will resolve gradually. However, you are advised to talk to your doctor if the side effects persist or worsen.

Country of origin

India

Manufacturer/Marketer address

Sco-96, Basement, Sector-5, Panchkula (Haryana) India
Other Info - NO49690

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Aug 5, 2025 | 11:37 AM IST

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Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/019384s066lbl.pdf
  2. https://www.drugs.com/mtm/norfloxacin.html
  3. https://www.medsafe.govt.nz/consumers/cmi/a/arrow-norfloxacin.pdf
  4. https://www.nps.org.au/assets/medicines/79780e54-983f-4464-89f5-a53300feeb23-reduced.pdf
  5. https://www.efda.gov.et/wp-content/uploads/2023/08/Norfloxacin_Norfloxacin-Tablets_medicamen-Biotech-Ltd.pdf
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